EE9700207A - Bicyclic amidine derivatives for therapeutic use - Google Patents

Bicyclic amidine derivatives for therapeutic use

Info

Publication number
EE9700207A
EE9700207A EE9700207A EE9700207A EE9700207A EE 9700207 A EE9700207 A EE 9700207A EE 9700207 A EE9700207 A EE 9700207A EE 9700207 A EE9700207 A EE 9700207A EE 9700207 A EE9700207 A EE 9700207A
Authority
EE
Estonia
Prior art keywords
therapeutic use
amidine derivatives
bicyclic amidine
bicyclic
derivatives
Prior art date
Application number
EE9700207A
Other languages
Estonian (et)
Inventor
John Murray Robert
Macdonald James
Shakespeare William
Matz James
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE9700207A publication Critical patent/EE9700207A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9700207A 1995-08-10 1995-08-10 Bicyclic amidine derivatives for therapeutic use EE9700207A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1995/001896 WO1997006158A1 (en) 1995-08-10 1995-08-10 Bicyclic amidine derivatives useful in therapy

Publications (1)

Publication Number Publication Date
EE9700207A true EE9700207A (en) 1998-02-16

Family

ID=10768883

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700207A EE9700207A (en) 1995-08-10 1995-08-10 Bicyclic amidine derivatives for therapeutic use

Country Status (7)

Country Link
KR (1) KR970706272A (en)
BR (1) BR9509297A (en)
CZ (1) CZ287969B6 (en)
EE (1) EE9700207A (en)
IS (1) IS4452A (en)
SK (1) SK281442B6 (en)
WO (1) WO1997006158A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9701682D0 (en) * 1997-05-05 1997-05-05 Astra Ab Compounds
SE9701681D0 (en) * 1997-05-05 1997-05-05 Astra Ab New compounds
DE19844291A1 (en) * 1998-09-18 2000-03-23 Schering Ag New aminoalkylaminoalkyl-substituted benzoxazines or benzothiazines, are nitrogen monoxide synthase inhibitors useful for treating neurodegenerative, inflammatory, autoimmune or cardiovascular disease
US7115557B2 (en) 1998-09-25 2006-10-03 Sciaticon Ab Use of certain drugs for treating nerve root injury
SE9803710L (en) 1998-09-25 2000-03-26 A & Science Invest Ab Use of certain substances for the treatment of nerve root damage
WO2001087834A1 (en) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
MY136316A (en) 2001-02-13 2008-09-30 Sanofi Aventis Deutschland Acylated 6,7,8,9-tetrahydro-5h-benzocycloheptenyl amines and their use as pharmaceutical.
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
TW200403223A (en) 2002-02-15 2004-03-01 Glaxo Group Ltd Novel compounds
EP1388535A1 (en) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylated arylcycloalkylamines and their use as pharmaceuticals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885985A (en) * 1993-03-23 1999-03-23 Astra Aktiebolag Guanidine derivatives useful in therapy
PL180081B1 (en) * 1993-08-12 2000-12-29 Astra Ab Amidine derivatives exhibiting activity of nitrogen oxide synthetase
CA2188680A1 (en) * 1994-05-07 1996-01-25 James Edwin Macdonald Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase

Also Published As

Publication number Publication date
KR970706272A (en) 1997-11-03
BR9509297A (en) 1998-07-07
CZ287969B6 (en) 2001-03-14
SK281442B6 (en) 2001-03-12
CZ108697A3 (en) 1998-04-15
SK39097A3 (en) 1998-08-05
IS4452A (en) 1997-03-25
WO1997006158A1 (en) 1997-02-20

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