EE200000157A - Asümmeetriliste tsükliliste uureade valmistamine monoatsüülitud diamiini vaheühendi kaudu - Google Patents

Asümmeetriliste tsükliliste uureade valmistamine monoatsüülitud diamiini vaheühendi kaudu

Info

Publication number
EE200000157A
EE200000157A EEP200000157A EEP200000157A EE200000157A EE 200000157 A EE200000157 A EE 200000157A EE P200000157 A EEP200000157 A EE P200000157A EE P200000157 A EEP200000157 A EE P200000157A EE 200000157 A EE200000157 A EE 200000157A
Authority
EE
Estonia
Prior art keywords
preparation
cyclic ureas
diamine intermediate
asymmetric cyclic
monoacylated
Prior art date
Application number
EEP200000157A
Other languages
English (en)
Inventor
Eugene Waltermire Robert
R. P. Stone Benjamin
Anzalone Luigi
M. Fortunak Joseph
D. Harris Gregory
I. Valvis Ioannis
Original Assignee
Dupont Pharmaceuticals Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Pharmaceuticals Company filed Critical Dupont Pharmaceuticals Company
Publication of EE200000157A publication Critical patent/EE200000157A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28Radicals substituted by nitrogen atoms
EEP200000157A 1997-10-06 1998-10-06 Asümmeetriliste tsükliliste uureade valmistamine monoatsüülitud diamiini vaheühendi kaudu EE200000157A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6119597P 1997-10-06 1997-10-06
PCT/US1998/021051 WO1999018085A2 (en) 1997-10-06 1998-10-06 Preparation of asymmetric cyclic ureas through a monoacylated diamine intermediate

Publications (1)

Publication Number Publication Date
EE200000157A true EE200000157A (et) 2001-02-15

Family

ID=22034252

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000157A EE200000157A (et) 1997-10-06 1998-10-06 Asümmeetriliste tsükliliste uureade valmistamine monoatsüülitud diamiini vaheühendi kaudu

Country Status (19)

Country Link
US (2) US6218534B1 (et)
EP (1) EP1025092A2 (et)
JP (1) JP2001519335A (et)
KR (1) KR20010024403A (et)
CN (1) CN1273586A (et)
AR (1) AR017763A1 (et)
AU (1) AU9788198A (et)
BR (1) BR9815400A (et)
CA (1) CA2304513A1 (et)
EE (1) EE200000157A (et)
HR (1) HRP980538A2 (et)
HU (1) HUP0003933A3 (et)
IL (1) IL135470A0 (et)
NO (1) NO20001749L (et)
PL (1) PL340238A1 (et)
SK (1) SK4732000A3 (et)
TW (1) TW505649B (et)
WO (1) WO1999018085A2 (et)
ZA (1) ZA989099B (et)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7449111B2 (en) * 2003-07-30 2008-11-11 Arkema Inc. Resins containing ionic or ionizable groups with small domain sizes and improved conductivity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610294A (en) 1991-10-11 1997-03-11 The Du Pont Merck Pharmaceutical Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
US5530124A (en) 1994-06-30 1996-06-25 The Dupont Merck Pharmaceutical Company Method for preparing cyclic ureas and their use for the synthesis of HIV protease inhibitors
US5532356A (en) 1995-06-06 1996-07-02 The Dupont Merck Pharmaceutical Company Method for preparing N,N'-disubstituted cyclic ureas
US5532357A (en) 1995-06-07 1996-07-02 The Dupont Merck Pharmaceutical Company Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas
US5998614A (en) * 1997-07-07 1999-12-07 Dupont Pharmaceuticals Company Preparation of asymmetric cyclic ureas using an alkali metal in liquid ammonia process

Also Published As

Publication number Publication date
JP2001519335A (ja) 2001-10-23
KR20010024403A (ko) 2001-03-26
SK4732000A3 (en) 2001-03-12
WO1999018085A2 (en) 1999-04-15
WO1999018085A3 (en) 1999-06-24
US20010020093A1 (en) 2001-09-06
EP1025092A2 (en) 2000-08-09
HUP0003933A2 (hu) 2001-10-28
ZA989099B (en) 2000-04-06
CA2304513A1 (en) 1999-04-15
US6452000B2 (en) 2002-09-17
NO20001749L (no) 2000-06-05
NO20001749D0 (no) 2000-04-05
HUP0003933A3 (en) 2001-12-28
CN1273586A (zh) 2000-11-15
US6218534B1 (en) 2001-04-17
IL135470A0 (en) 2001-05-20
HRP980538A2 (en) 1999-10-31
AU9788198A (en) 1999-04-27
AR017763A1 (es) 2001-10-24
BR9815400A (pt) 2001-09-25
PL340238A1 (en) 2001-01-29
TW505649B (en) 2002-10-11

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