ECSP982727A - IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K) - Google Patents

IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K)

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Publication number
ECSP982727A
ECSP982727A ECSP982727A ECSP982727A EC SP982727 A ECSP982727 A EC SP982727A EC SP982727 A ECSP982727 A EC SP982727A EC SP982727 A ECSP982727 A EC SP982727A
Authority
EC
Ecuador
Prior art keywords
formula
compound
ilalquilo
hetero
imidazole
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Stuart B Rosenblum
Robert G Aslanian
John J Piwinski
Wayne D Vaccaro
Daniel M Solomon
Ronald L Wolin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982727 priority Critical patent/ECSP982727A/en
Publication of ECSP982727A publication Critical patent/ECSP982727A/en

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Abstract

Se describen compuestos que tienen la fórmula I (gráfico), o sales o solvatos de los mismos farmacéuticamente aceptables. También se describen composiciones farmacéuticamente que comprenden un portador farmacéuticamente aceptable y una cantidad eficaz de un compuesto de fórmula I. Además se describe un método para tratar alergias (por ejemplo asma), inflamación hipotensión, aumento de la presión intraocular (tal como glaucoma)- es decir un método para disminuir la presión intraocular, los desordenes del sueño, los estados de hiper e hipo motilidad, y la secreción ácida del tracto gastrointestinal, la hipo e hiper actividad del sistema nervioso central (por ejemplo agitación y depresión), y otros desórdenes del CNS (tal como enfermedad de Azheimer, esquizofrenia, obesidad y migraña) que comprende administrar una cantidad eficaz de un compuesto de fórmula I a un paciente que necesita dicho tratamiento. También se describen métodos para el tratamiento de las respuestas alérgicas de las vias respiratorias superiores que comprende administrar un compuesto o una sal o solvato del mismo de acuerdo con la fórmula I en combinación o en mezcla con un antagonista receptor de histamina K1Compounds having formula I (graph), or pharmaceutically acceptable salts or solvates thereof are described. Pharmaceutically compositions comprising a pharmaceutically acceptable carrier and an effective amount of a compound of formula I are also described. In addition, a method of treating allergies (eg, asthma), inflammation, hypotension, increased intraocular pressure (such as glaucoma) is described. that is, a method to decrease intraocular pressure, sleep disorders, hyper and hypomotility states, and acid secretion from the gastrointestinal tract, hypo and hyper activity of the central nervous system (for example agitation and depression), and others CNS disorders (such as Azheimer's disease, schizophrenia, obesity, and migraine) comprising administering an effective amount of a compound of formula I to a patient in need of such treatment. Methods for the treatment of allergic responses of the upper respiratory tract are also described which comprises administering a compound or a salt or solvate thereof according to formula I in combination or in admixture with a histamine K1 receptor antagonist.

ECSP982727 1998-11-05 1998-11-05 IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K) ECSP982727A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982727 ECSP982727A (en) 1998-11-05 1998-11-05 IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982727 ECSP982727A (en) 1998-11-05 1998-11-05 IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K)

Publications (1)

Publication Number Publication Date
ECSP982727A true ECSP982727A (en) 1999-05-06

Family

ID=42043645

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982727 ECSP982727A (en) 1998-11-05 1998-11-05 IMIDAZOLE ILALQUILO SUBSTITUTED WITH A HETERO-CYCLE RING OF FIVE, SIX OR SEVEN MEMBERS CONTAINING A NITROGEN ATOM (CASE 0797K)

Country Status (1)

Country Link
EC (1) ECSP982727A (en)

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