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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
33-epicloro-33 desoxiascomicina de la fórmula I: (gráfico), y diferentes formas tautoméricas o solvatadas de la misma, en forma cristalina, tal como la forma A y la forma B. Su preparación involucra convertir apropiadamente el compuesto amorfo de la fórmula 1, o el compuesto de la fórmula I en una forma diferente de la forma A, o el compuesto de la fórmula I en una forma diferente de la forma B, respectivamente, a partir de una solución del mismo, bajo condiciones que induzcan cristalización, o bajo condiciones que induzcan cristalización prefencial de la forma A ó B respectivamente, estos crsitales se indican particularmente para utilizarse en la preparción de formas galénicas locales del compuesto para uso farmacéutico, por ejemplo cremas, emulsiones y uguentos.33-epichloro-33 deoxiascomycin of formula I: (graph), and different tautomeric or solvated forms thereof, in crystalline form, such as form A and form B. Their preparation involves appropriately converting the amorphous compound of the formula 1, or the compound of formula I in a different form than form A, or the compound of formula I in a different form of form B, respectively, from a solution thereof, under conditions that induce crystallization, or under conditions that induce pre-crystallization of form A or B respectively, these crystals are particularly indicated for use in the preparation of local galenic forms of the compound for pharmaceutical use, for example creams, emulsions and ointments.
MACROLIDAS CRISTALINAS, A PROCESS FOR ITS PREPARATION, A PHARMACEUTICAL COMPOSITION AND THE USE OF SUCH COMPOUNDS FOR THE PREPARATION OF A MEDICINAL PRODUCT
Compound, processes for the production of a compound and for the conversion of a crystalline form to a compound, pharmaceutical formulation, use of a compound, and, process for treating a condition where thrombin inhibition is required or desired
CRYSTAL FORMS OF 11BETA - (4 - ACETILFENIL) - 20, 20, 21, 21, 21 - PENTAFLUORO - 17 - HIDROXI - 19 - NOR - 17ALFA - PREGNA - 4, 9 - DIEN - 3 - ONA, METHODS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS THAT CONTAIN THEM FOR EMPLOYMENT IN THE TREATMENT OF MIOMAS AND CANCER OF BREAST.