ECSP17016757A - ANTI-LAG3 ANTIBODIES AND ANTIGEN BINDING FRAGMENTS - Google Patents

ANTI-LAG3 ANTIBODIES AND ANTIGEN BINDING FRAGMENTS

Info

Publication number
ECSP17016757A
ECSP17016757A ECIEPI201716757A ECPI201716757A ECSP17016757A EC SP17016757 A ECSP17016757 A EC SP17016757A EC IEPI201716757 A ECIEPI201716757 A EC IEPI201716757A EC PI201716757 A ECPI201716757 A EC PI201716757A EC SP17016757 A ECSP17016757 A EC SP17016757A
Authority
EC
Ecuador
Prior art keywords
antibodies
fragments
binding fragments
antigen binding
lag3 antibodies
Prior art date
Application number
ECIEPI201716757A
Other languages
Spanish (es)
Inventor
Gopalan Raghunathan
Laurence Fayadat-Dilman
Linda Liang
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of ECSP17016757A publication Critical patent/ECSP17016757A/en

Links

Abstract

La presente invención incluye anticuerpos y fragmentos de unión a antígeno de los mismos que se unen específicamente a LAG3 de ser humano o de mono cinomolgo así como cadenas de inmunoglobulina de los mismos y polinucleótidos que codifican los mismos junto con dispositivos de inyección que comprenden dichos anticuerpos o fragmentos. Las vacunas que incluyen dichos anticuerpos y fragmentos así como las composiciones que comprenden los anticuerpos y fragmentos (por ejemplo, incluyendo anticuerpos anti-PD1) se incluyen en la invención. También se proporcionan métodos para el tratamiento o la prevención de cáncer o infección usando dichas composiciones. Además, los métodos de expresión recombinante de los anticuerpos y fragmentos son parte de la presente invención.The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgus monkey LAG3 as well as immunoglobulin chains thereof and polynucleotides encoding the same together with injection devices comprising such antibodies. or fragments. Vaccines including such antibodies and fragments as well as compositions comprising the antibodies and fragments (eg, including anti-PD1 antibodies) are included in the invention. Methods for treating or preventing cancer or infection using such compositions are also provided. Furthermore, the recombinant expression methods of the antibodies and fragments are part of the present invention.

ECIEPI201716757A 2014-08-19 2017-03-17 ANTI-LAG3 ANTIBODIES AND ANTIGEN BINDING FRAGMENTS ECSP17016757A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462039081P 2014-08-19 2014-08-19

Publications (1)

Publication Number Publication Date
ECSP17016757A true ECSP17016757A (en) 2017-03-31

Family

ID=58951264

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201716757A ECSP17016757A (en) 2014-08-19 2017-03-17 ANTI-LAG3 ANTIBODIES AND ANTIGEN BINDING FRAGMENTS

Country Status (2)

Country Link
AR (1) AR103492A1 (en)
EC (1) ECSP17016757A (en)

Also Published As

Publication number Publication date
AR103492A1 (en) 2017-05-17

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