ECSP10010680A - TEST OF THE CARE POINT FOR THE DETECTION OF EXPOSURE OR IMMUNITY TO THE DENGUE VIRUS - Google Patents

TEST OF THE CARE POINT FOR THE DETECTION OF EXPOSURE OR IMMUNITY TO THE DENGUE VIRUS

Info

Publication number
ECSP10010680A
ECSP10010680A EC2010010680A ECSP10010680A ECSP10010680A EC SP10010680 A ECSP10010680 A EC SP10010680A EC 2010010680 A EC2010010680 A EC 2010010680A EC SP10010680 A ECSP10010680 A EC SP10010680A EC SP10010680 A ECSP10010680 A EC SP10010680A
Authority
EC
Ecuador
Prior art keywords
dengue virus
mandatory
detection
partner
exposure
Prior art date
Application number
EC2010010680A
Other languages
Spanish (es)
Inventor
Kumar Sil Bijon
yun ying Tan
Original Assignee
Mp Biomedicals Asia Pacific Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mp Biomedicals Asia Pacific Pte Ltd filed Critical Mp Biomedicals Asia Pacific Pte Ltd
Publication of ECSP10010680A publication Critical patent/ECSP10010680A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G01N2333/185—Flaviviruses or Group B arboviruses, e.g. yellow fever virus, japanese encephalitis, tick-borne encephalitis, dengue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención proporciona una "prueba del punto de cuidado" (POCT) para la detección de un sujeto que ha tenido la exposición a un virus del dengue o familiares inmunológicos del mismo o que ha alcanzado cierto nivel de inmunidad contra un antígeno del virus del dengue. El método está previsto, en parte, en la detección de un socio obligatorio (en general, los anticuerpos IgA) que es específico para el virus del dengue o familiares inmunológicos del mismo. La POCT comprende poner en contacto una muestra biológica del sujeto con una mezcla de componentes inmunogénicos específicos del virus del dengue, y determinar la presencia de un complejo que se forma entre un socio obligatorio (por ejemplo, anticuerpos IgA) en la muestra biológica y un componente inmunogénico específico del virus del dengue; y caracterizar al socio obligatorio en el complejo con un anticuerpo anti-socio obligatorio (por ejemplo, anti-humano IgA) conjugado con oro coloidal mediante la tecnología de flujo inverso.The present invention provides a "point of care test" (POCT) for the detection of a subject who has had exposure to a dengue virus or immunological relatives thereof or has reached a certain level of immunity against a virus antigen. dengue. The method is provided, in part, for the detection of a mandatory partner (in general, IgA antibodies) that is specific for dengue virus or immunological relatives thereof. POCT comprises contacting a biological sample of the subject with a mixture of specific immunogenic components of dengue virus, and determining the presence of a complex that forms between a mandatory partner (eg, IgA antibodies) in the biological sample and a specific immunogenic component of dengue virus; and characterize the mandatory partner in the complex with a mandatory anti-partner antibody (eg, anti-human IgA) conjugated to colloidal gold by reverse flow technology.

EC2010010680A 2008-05-15 2010-12-15 TEST OF THE CARE POINT FOR THE DETECTION OF EXPOSURE OR IMMUNITY TO THE DENGUE VIRUS ECSP10010680A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG200803904-2A SG157244A1 (en) 2008-05-15 2008-05-15 Point of care test for the detection of exposure or immunity to dengue virus

Publications (1)

Publication Number Publication Date
ECSP10010680A true ECSP10010680A (en) 2011-04-29

Family

ID=41318932

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010680A ECSP10010680A (en) 2008-05-15 2010-12-15 TEST OF THE CARE POINT FOR THE DETECTION OF EXPOSURE OR IMMUNITY TO THE DENGUE VIRUS

Country Status (7)

Country Link
BR (1) BRPI0915291A2 (en)
CO (1) CO6311040A2 (en)
CR (1) CR11836A (en)
EC (1) ECSP10010680A (en)
MX (1) MX2010012363A (en)
SG (1) SG157244A1 (en)
WO (1) WO2009139725A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG165194A1 (en) * 2009-03-20 2010-10-28 Mp Biomedicals Asia Pacific Pte Ltd Point of care test for the detection of exposure to hev immunoglobulin a (iga)
CN102393454A (en) * 2011-08-24 2012-03-28 中国检验检疫科学研究院 Colloidal gold test strip for detecting dengue virus antibody and preparation method and application thereof
PL3539565T3 (en) 2013-03-15 2023-09-25 Takeda Vaccines, Inc. Compositions and methods for dengue virus chimeric constructs in vaccines
SG10201404571PA (en) * 2014-08-01 2016-03-30 Mp Biomedicals Asia Pacific Pte Ltd Method and kit for detecting a dengue virus infection
WO2020051334A1 (en) 2018-09-05 2020-03-12 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
US11464815B2 (en) 2018-09-05 2022-10-11 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
WO2021202992A2 (en) * 2020-04-03 2021-10-07 Lawrence Loomis Rapid point of care assay for the detection of the asymptomatic carrier state of covid-19
WO2021216276A1 (en) * 2020-04-24 2021-10-28 Massachusetts Institute Of Technology Rapid, point of care detection of neutralizing antibodies against a virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03148066A (en) * 1989-11-06 1991-06-24 Nippon Zeon Co Ltd Membrane for diagnosing virus infectious disease and diagnostic method
DE69834041T2 (en) * 1997-07-31 2006-12-14 Hawaii Biotech, Inc., Aiea RECOMBINANT DIMERIC CROP PROTEINS AS A VACCINE AGAINST A FLAVIVAL INFECTION
FR2767324B1 (en) * 1997-08-14 2001-04-06 Pasteur Institut USE OF RECOMBINANT ENVELOPE PROTEINS FOR THE DIAGNOSIS OF DENGUE VIRUS
WO2005014627A1 (en) * 2003-08-07 2005-02-17 International Centre For Genetic Engineering And Biotechnology Recombinant dengue multi epitope proteins as diagnostic intermediates
SG137711A1 (en) * 2006-05-11 2007-12-28 Nat Environment Agency Antigen capture anti-dengue iga elisa (aca-elisa) for the detection of a flavivirus specific antibody

Also Published As

Publication number Publication date
SG157244A1 (en) 2009-12-29
CO6311040A2 (en) 2011-08-22
CR11836A (en) 2011-06-07
BRPI0915291A2 (en) 2016-02-16
WO2009139725A1 (en) 2009-11-19
MX2010012363A (en) 2011-04-11

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