ECSP078024A - Inhibidores de la adenilato ciclasa soluble - Google Patents

Inhibidores de la adenilato ciclasa soluble

Info

Publication number
ECSP078024A
ECSP078024A EC2007008024A ECSP078024A ECSP078024A EC SP078024 A ECSP078024 A EC SP078024A EC 2007008024 A EC2007008024 A EC 2007008024A EC SP078024 A ECSP078024 A EC SP078024A EC SP078024 A ECSP078024 A EC SP078024A
Authority
EC
Ecuador
Prior art keywords
adenylate
cycling
inhibitors
soluble
medicament
Prior art date
Application number
EC2007008024A
Other languages
English (en)
Inventor
Duy Nguyen
Bernd Buchmann
Martin Fritsch
Ulf Boemer
Bernd Menzenbach
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of ECSP078024A publication Critical patent/ECSP078024A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

La invención se relaciona con compuestos de la fórmula general (I), y con su preparación y su uso como medicamento.
EC2007008024A 2005-06-08 2007-12-17 Inhibidores de la adenilato ciclasa soluble ECSP078024A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005027274A DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase

Publications (1)

Publication Number Publication Date
ECSP078024A true ECSP078024A (es) 2008-01-23

Family

ID=37398540

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007008024A ECSP078024A (es) 2005-06-08 2007-12-17 Inhibidores de la adenilato ciclasa soluble

Country Status (23)

Country Link
EP (1) EP1888058B1 (es)
JP (1) JP2008542422A (es)
KR (1) KR20080016617A (es)
CN (1) CN101193631A (es)
AR (1) AR054378A1 (es)
AT (1) ATE431736T1 (es)
AU (1) AU2006256857A1 (es)
BR (1) BRPI0610934A2 (es)
CA (1) CA2606692A1 (es)
CR (1) CR9578A (es)
DE (2) DE102005027274A1 (es)
DO (1) DOP2006000130A (es)
EA (1) EA200702590A1 (es)
EC (1) ECSP078024A (es)
GT (1) GT200600244A (es)
IL (1) IL186914A0 (es)
MX (1) MX2007015493A (es)
NO (1) NO20080104L (es)
PE (1) PE20061488A1 (es)
TW (1) TW200716090A (es)
UY (1) UY29583A1 (es)
WO (1) WO2006131398A2 (es)
ZA (1) ZA200800153B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006014319B4 (de) * 2006-03-23 2009-01-08 Bayer Schering Pharma Aktiengesellschaft Inhibitoren der löslichen Adenylatzyklase
EP2036906A1 (de) * 2007-09-05 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Azaindole als Inhibitoren der löslichen Adenylatzyklase
MX2024006739A (es) 2021-12-01 2024-06-19 Pfizer Derivados de acido 3-fenil-1-benzotiofeno-2-carboxilico como inhibidores de alfa cetoacido deshidrogenasa quinasa de cadena ramificada para el tratamiento de diabetes, enfermedad renal, esteatohepatitis no alcoholica (nash) e insuficiencia cardiaca.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (fr) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie Derives amides, procede pour leur fabrication et compositions fongicides les contenant
US20020064849A1 (en) * 2000-09-05 2002-05-30 Herr John C. Human soluble testicular adenylyl cyclase
NZ528752A (en) * 2001-06-28 2006-06-30 Pfizer Prod Inc Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (APO B) secretion
AU2002327627B2 (en) * 2001-09-14 2006-09-14 Methylgene Inc. Inhibitors of histone deacetylase
UA79504C2 (en) * 2002-11-07 2007-06-25 Organon Nv Indols for treating diseases associated with androgen receptors
SI1663242T1 (sl) * 2003-08-07 2011-09-30 Rigel Pharmaceuticals Inc 2,4-pirimidindiaminske spojine in uporabe kot antiproliferativna sredstva
EP1677731A4 (en) * 2003-10-09 2009-05-06 Aton Pharma Inc THIOPHENE AND BENZOTHIOPHENE DERIVATIVES OF HYDROXAMIC ACID
EP1706114B1 (en) * 2004-01-21 2012-12-26 Cornell Research Foundation, Inc. Chemical inhibitors of soluble adenylyl cyclase (sac)
MXPA06010900A (es) * 2004-03-26 2007-02-21 Methylgene Inc Inhibidores de histona desacetilasa.
DE102004047272A1 (de) * 2004-09-24 2006-04-06 Schering Ag Inhibitoren der löslichen Adenylatzyklase

Also Published As

Publication number Publication date
EA200702590A1 (ru) 2008-06-30
DE602006006908D1 (de) 2009-07-02
WO2006131398A2 (en) 2006-12-14
DE102005027274A1 (de) 2006-12-14
NO20080104L (no) 2008-03-03
EP1888058B1 (en) 2009-05-20
AR054378A1 (es) 2007-06-20
BRPI0610934A2 (pt) 2010-08-03
CA2606692A1 (en) 2006-12-14
JP2008542422A (ja) 2008-11-27
WO2006131398A3 (en) 2007-04-19
MX2007015493A (es) 2008-02-22
IL186914A0 (en) 2008-02-09
ZA200800153B (en) 2009-03-25
CN101193631A (zh) 2008-06-04
AU2006256857A1 (en) 2006-12-14
EP1888058A2 (en) 2008-02-20
KR20080016617A (ko) 2008-02-21
CR9578A (es) 2008-03-06
PE20061488A1 (es) 2007-02-03
ATE431736T1 (de) 2009-06-15
DOP2006000130A (es) 2006-11-30
GT200600244A (es) 2007-01-23
TW200716090A (en) 2007-05-01
UY29583A1 (es) 2007-01-31

Similar Documents

Publication Publication Date Title
EA200870193A1 (ru) Цитотоксические агенты, включающие новые производные томаймицина, и их терапевтическое применение
DOP2010000047A (es) Compuestos de pirazol y su uso como inhibidores de raf
NO20090295L (no) Substituerte heteroarylderivater
EA201790678A1 (ru) Бициклические гетероарильные соединения
CR11861A (es) Compuestos organicos
BRPI0915084B8 (pt) composto, e, composição farmacêutica
BR122013025375B8 (pt) compostos orgânicos, seus métodos de preparo e uso, bem como composições farmacêuticas
MY153921A (en) Aminopyrazole derivatives
EA201000614A1 (ru) Производные пурина как лиганды аденозинового рецептора а
EA200870514A1 (ru) Ацетиленовые гетероарильные соединения
EA201170703A1 (ru) Производные адамантилбензамида
MX341849B (es) Nitrilos espirociclicos como inhibidores de proteasa.
EA200870515A1 (ru) Моноциклические гетероарильные соединения
BRPI0513149A (pt) uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituìdas no tratamento de náuseas e vÈmito
NO20081207L (no) Isoquinolines as IGF-1R inhibitors
CR9391A (es) Derivados de indanil-piperazinas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
CR9058A (es) Derivados de indol como inhibidores de la adenilato ciclasa soluble
UY30801A1 (es) Compuestos calciliticos
ATE445593T1 (de) Acetylenderivate
PA8657801A1 (es) Aminalcoholes triciclicos, procedimientos para su preparacion
UY28917A1 (es) Derivados de tetrahidroisoquinolilsulfonamidas composiciones farmaceuticas y su uso terapeutico
ATE417849T1 (de) Pyrazoloä4,3-düpyrimidine
ECSP078024A (es) Inhibidores de la adenilato ciclasa soluble
DE602007005387D1 (de) Ptors
UY30235A1 (es) Inhibidores de la adenilato ciclasa soluble