ECSP066329A - PENTANOL DERIVATIVES HETEROCYCLICLY REPLACED, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY - Google Patents
PENTANOL DERIVATIVES HETEROCYCLICLY REPLACED, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORYInfo
- Publication number
- ECSP066329A ECSP066329A EC2006006329A ECSP066329A ECSP066329A EC SP066329 A ECSP066329 A EC SP066329A EC 2006006329 A EC2006006329 A EC 2006006329A EC SP066329 A ECSP066329 A EC SP066329A EC SP066329 A ECSP066329 A EC SP066329A
- Authority
- EC
- Ecuador
- Prior art keywords
- preparation
- heterocyclicly
- inflammatory
- replaced
- procedure
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
La invención se refiere a derivados de pentanol de la fórmula general (I) sustituidos con quinazolina, quinoxalina, cinolina, indazol, ftalazina, naftiridina, benzotiazol, dihidroindolona, dihidroisoindolona, bencimidazol o indol, a un procedimiento para su preparación y a su uso como antiinflamatorios.The invention relates to pentanol derivatives of the general formula (I) substituted with quinazoline, quinoxaline, cinoline, indazol, phthalazine, naphthyridine, benzothiazole, dihydroindolone, dihydroisoindolone, benzimidazole or indole, a process for its preparation and its use as anti-inflammatories. .
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2003130358 DE10330358A1 (en) | 2003-07-01 | 2003-07-01 | New arylalkanol derivatives used for treating e.g. respiratory diseases, joint diseases, vascular inflammations, skin disorders, kidney and liver diseases and neurological diseases |
DE2003146939 DE10346939A1 (en) | 2003-10-06 | 2003-10-06 | New arylalkanol derivatives used for treating e.g. respiratory diseases, joint diseases, vascular inflammations, skin disorders, kidney and liver diseases and neurological diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP066329A true ECSP066329A (en) | 2006-07-28 |
Family
ID=33566017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2006006329A ECSP066329A (en) | 2003-07-01 | 2006-01-30 | PENTANOL DERIVATIVES HETEROCYCLICLY REPLACED, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1638945A1 (en) |
JP (1) | JP2008529963A (en) |
KR (1) | KR20060027376A (en) |
AU (1) | AU2004254205A1 (en) |
BR (1) | BRPI0412231A (en) |
CA (1) | CA2531060A1 (en) |
EA (1) | EA200600148A1 (en) |
EC (1) | ECSP066329A (en) |
IL (1) | IL172899A0 (en) |
MX (1) | MXPA06000169A (en) |
NO (1) | NO20060534L (en) |
RS (1) | RS20050974A (en) |
WO (1) | WO2005003098A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
DE502004002403D1 (en) | 2003-10-08 | 2007-02-01 | Schering Ag | TETRAHYDRONAPHTHALIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN INFLAMMATORY INHIBITION |
US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
ES2414479T3 (en) | 2005-04-14 | 2013-07-19 | Glaxo Group Limited | Indazoles as glucocorticoid receptor ligands |
DE102005030292A1 (en) * | 2005-06-24 | 2007-01-11 | Schering Ag | Nonsteroidal progesterone receptor modulators |
DE102005030293A1 (en) * | 2005-06-24 | 2007-01-04 | Schering Ag | Use of nonsteroidal progesterone receptor modulators |
GB0522880D0 (en) * | 2005-11-09 | 2005-12-21 | Glaxo Group Ltd | Novel compounds |
EP1834948A1 (en) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiinflammatory drugs |
TW200811111A (en) | 2006-04-20 | 2008-03-01 | Glaxo Group Ltd | Novel compounds |
EP1878717A1 (en) | 2006-07-14 | 2008-01-16 | Bayer Schering Pharma Aktiengesellschaft | Benzyl amines, a process for their production and their use as anti-inflammatory agents |
GB0620385D0 (en) | 2006-10-13 | 2006-11-22 | Glaxo Group Ltd | Novel compounds |
GB0620406D0 (en) * | 2006-10-13 | 2006-11-22 | Glaxo Group Ltd | Novel compounds |
EP2089355A2 (en) | 2006-11-01 | 2009-08-19 | Brystol-Myers Squibb Company | Modulators of glucocorticoid receptor, ap-1, and/or nf- kappa b activity and use thereof |
EP1921068A1 (en) * | 2006-11-08 | 2008-05-14 | Bayer Schering Pharma Aktiengesellschaft | Indazole and indole derivatives as anti-inflammatory agents |
WO2008055709A1 (en) * | 2006-11-08 | 2008-05-15 | Bayer Schering Pharma Aktiengesellschaft | Indazole and indole derivatives as anti -inflammatory agents |
EP1921067A1 (en) * | 2006-11-08 | 2008-05-14 | Bayer Schering Pharma Aktiengesellschaft | Indole and indazole derivatives as anti-inflammatory agents |
KR20090077946A (en) * | 2006-11-09 | 2009-07-16 | 보오슈 앤드 롬 인코포레이팃드 | Synthesis of selected stereoisomers of certain substituted alcohols |
UY30805A1 (en) * | 2006-12-21 | 2008-07-31 | Bayer Schering Pharma Ag | NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS |
GB0720556D0 (en) * | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
GB0720544D0 (en) * | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
GB0720549D0 (en) * | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
EP2062880A1 (en) | 2007-11-22 | 2009-05-27 | Bayer Schering Pharma Aktiengesellschaft | 5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents |
WO2009069736A1 (en) * | 2007-11-28 | 2009-06-04 | Kyowa Hakko Kirin Co., Ltd. | Nitrogenated compound |
US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
EA019441B1 (en) | 2008-12-30 | 2014-03-31 | Палмаджен Терепьютикс (Инфлеммейшн) Лимитед | Sulfonamide compounds for the treatment of respiratory disorders |
WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19723722A1 (en) * | 1997-05-30 | 1998-12-10 | Schering Ag | Nonsteroidal progestogens |
DE19856475A1 (en) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nonsteroidal anti-inflammatories |
DE10038639A1 (en) * | 2000-07-28 | 2002-02-21 | Schering Ag | New and known N-aryl 2-hydroxy-omega-arylalkanamide derivatives, useful e.g. for treating inflammatory diseases such as rheumatism |
US6960581B2 (en) * | 2002-01-14 | 2005-11-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof |
DE10215316C1 (en) * | 2002-04-02 | 2003-12-18 | Schering Ag | Quinoline and isoquinoline derivatives, a pharmaceutical agent and their use as anti-inflammatory agents |
-
2004
- 2004-06-22 KR KR1020057025375A patent/KR20060027376A/en not_active Application Discontinuation
- 2004-06-22 EP EP04740190A patent/EP1638945A1/en not_active Withdrawn
- 2004-06-22 BR BRPI0412231-3A patent/BRPI0412231A/en not_active IP Right Cessation
- 2004-06-22 AU AU2004254205A patent/AU2004254205A1/en not_active Abandoned
- 2004-06-22 WO PCT/EP2004/006765 patent/WO2005003098A1/en active Application Filing
- 2004-06-22 JP JP2006516031A patent/JP2008529963A/en not_active Withdrawn
- 2004-06-22 RS YUP-2005/0974A patent/RS20050974A/en unknown
- 2004-06-22 EA EA200600148A patent/EA200600148A1/en unknown
- 2004-06-22 CA CA002531060A patent/CA2531060A1/en not_active Abandoned
- 2004-06-22 MX MXPA06000169A patent/MXPA06000169A/en unknown
-
2005
- 2005-12-29 IL IL172899A patent/IL172899A0/en unknown
-
2006
- 2006-01-30 EC EC2006006329A patent/ECSP066329A/en unknown
- 2006-02-01 NO NO20060534A patent/NO20060534L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20060027376A (en) | 2006-03-27 |
BRPI0412231A (en) | 2006-08-22 |
EA200600148A1 (en) | 2006-08-25 |
MXPA06000169A (en) | 2006-04-27 |
IL172899A0 (en) | 2006-06-11 |
WO2005003098B1 (en) | 2005-03-03 |
CA2531060A1 (en) | 2005-01-13 |
NO20060534L (en) | 2006-04-03 |
EP1638945A1 (en) | 2006-03-29 |
WO2005003098A1 (en) | 2005-01-13 |
AU2004254205A1 (en) | 2005-01-13 |
RS20050974A (en) | 2007-09-21 |
JP2008529963A (en) | 2008-08-07 |
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