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Application filed by Vertex PharmafiledCriticalVertex Pharma
Publication of ECSP034715ApublicationCriticalpatent/ECSP034715A/en
El invento se refiere a la química medicinal y se refiere a los compuestos de pirazol que son inhibidores de protein quinasa, especialmente inhibidores de ERK, composiciones que contienen dichos compuestos y métodos de uso. Los compuestos son útiles para tratar el cáncer y otras enfermedades que son aliviados por los inhibidores de protein quinasa.The invention relates to medicinal chemistry and refers to pyrazole compounds that are protein kinase inhibitors, especially ERK inhibitors, compositions containing said compounds and methods of use. The compounds are useful for treating cancer and other diseases that are relieved by protein kinase inhibitors.
ECSP0347152001-02-092003-08-07
ERK2 HETEROCICLIC INHIBITORS AND THEIR USES OF THE SAME
ECSP034715A
(en)
Compounds derived from nitrogen heterocycles, antagonists of apoptosis protein inhibitors; its pharmaceutical compositions; and use of said compounds for the treatment of cancer.