UY29370A1 - DERIVATIVES OF TIAZOL, COMPOSITIONS THAT CONTAIN IT, PREPARATION PROCEDURES AND APPLICATIONS - Google Patents

DERIVATIVES OF TIAZOL, COMPOSITIONS THAT CONTAIN IT, PREPARATION PROCEDURES AND APPLICATIONS

Info

Publication number
UY29370A1
UY29370A1 UY29370A UY29370A UY29370A1 UY 29370 A1 UY29370 A1 UY 29370A1 UY 29370 A UY29370 A UY 29370A UY 29370 A UY29370 A UY 29370A UY 29370 A1 UY29370 A1 UY 29370A1
Authority
UY
Uruguay
Prior art keywords
tiazol
derivatives
compositions
contain
applications
Prior art date
Application number
UY29370A
Other languages
Spanish (es)
Inventor
Sarah King
Andrew Baxter
Austen Pimm
Chris Luckhurst
Mark Furber
James Reuberson
Ian Millichip
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY29370A1 publication Critical patent/UY29370A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención proporciona compuestos de fórmula (I), o una sal farmacéuticamente aceptable de los mismos, en donde A, R1, R2, y R3, son como se define en la memoria descriptiva; un proceso para su preparación; composiciones farmacéuticas que los contienen; y su uso en terapia.The invention provides compounds of formula (I), or a pharmaceutically acceptable salt thereof, wherein A, R1, R2, and R3, are as defined in the specification; a process for its preparation; pharmaceutical compositions containing them; and its use in therapy.

UY29370A 2005-02-11 2006-02-10 DERIVATIVES OF TIAZOL, COMPOSITIONS THAT CONTAIN IT, PREPARATION PROCEDURES AND APPLICATIONS UY29370A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0500336 2005-02-11

Publications (1)

Publication Number Publication Date
UY29370A1 true UY29370A1 (en) 2006-10-02

Family

ID=36793310

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29370A UY29370A1 (en) 2005-02-11 2006-02-10 DERIVATIVES OF TIAZOL, COMPOSITIONS THAT CONTAIN IT, PREPARATION PROCEDURES AND APPLICATIONS

Country Status (4)

Country Link
AR (1) AR052900A1 (en)
TW (1) TW200639156A (en)
UY (1) UY29370A1 (en)
WO (1) WO2006085815A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014078322A1 (en) * 2012-11-13 2014-05-22 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
MY197094A (en) 2015-02-16 2023-05-24 Univ Queensland Sulfonylureas and related compounds and use of same
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses
WO2019008029A1 (en) 2017-07-07 2019-01-10 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
BR112020000259A2 (en) 2017-07-07 2020-07-14 Inflazome Limited new sulfonamide-carboxamide compounds
RU2020110394A (en) 2017-08-15 2022-01-20 Инфлазоум Лимитед NEW COMPOUNDS OF SULFONAMIDE CARBOXAMIDES
US11518739B2 (en) 2017-08-15 2022-12-06 Inflazome Limited Sulfonamide carboxamide compounds
TW201910317A (en) * 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 Novel compound
UY37845A (en) * 2017-08-15 2020-06-30 Inflazome Ltd SULFONYLUREAS AND SULPHONYLTIOUREAS USEFUL AS INHIBITORS OF NLRP3
EP3668843A1 (en) * 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
BR112020003014A2 (en) 2017-08-15 2020-07-28 Inflazome Limited sulfonylureas and sulfonylthioureas as inhibitors of vnlrp3
US12221434B2 (en) 2017-11-09 2025-02-11 Inflazome Limited Sulfonamide carboxamide compounds
BR112020008981A2 (en) 2017-11-09 2020-11-17 Inflazome Limited new sulfonamide carboxamide compounds
EP3759077A1 (en) 2018-03-02 2021-01-06 Inflazome Limited Novel compounds
CN113056451A (en) * 2018-10-24 2021-06-29 诺华股份有限公司 Compounds and compositions for treating conditions associated with NLRP activity
SG10201909596RA (en) * 2019-10-14 2021-05-28 Esco Aster Pte Ltd Synthesis of Tyrosine Kinase Inhibitors
WO2025163462A1 (en) * 2024-02-02 2025-08-07 삼진제약주식회사 Heterocyclic derivatives as mrgprx2 antagonists and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0885890A1 (en) * 1996-02-26 1998-12-23 Sumitomo Pharmaceuticals Company, Limited Sulfonylureidopyrazole derivatives
EP1441732A2 (en) * 2001-11-08 2004-08-04 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivative and pharmaceutical use thereof
CL2004000545A1 (en) * 2003-03-18 2005-01-28 Pharmacia Corp Sa Organizada B USE OF AN ANTAGONIST OF ALDOSTERONE RECEPTORS AND AN ENDOTHELINE RECEIVER ANTAGONIST FOR THE TREATMENT OR PROFILAXIS OF A PATHOLOGICAL CONDITION RELATED TO HYPERTENSION, RENAL DYSFUNCTION, INSULINOPATHY AND CARDIOVASCUL DISEASES

Also Published As

Publication number Publication date
AR052900A1 (en) 2007-04-11
TW200639156A (en) 2006-11-16
WO2006085815A1 (en) 2006-08-17

Similar Documents

Publication Publication Date Title
UY29370A1 (en) DERIVATIVES OF TIAZOL, COMPOSITIONS THAT CONTAIN IT, PREPARATION PROCEDURES AND APPLICATIONS
UY29087A1 (en) ADAMANTILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USE
UY29781A1 (en) DIAZASPIRO SUBSTITUTE COMPOUNDS, PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS OR SALTS, PREPARATION METHODS AND USES
UY30976A1 (en) NEW DERIVATIVES OF QUINOLINA, PHARMACCUTIC COMPOSITIONS THAT CONTAIN THEM, PREPARATION PROCESSES AND APPLICATIONS.
GT200600518A (en) PIRIMIDINE DERIVATIVES
UY29795A1 (en) ADENINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PREPARATION PROCESSES AND APPLICATIONS
UY28342A1 (en) NEW COMPOUNDS
UY29562A1 (en) AMINO BENZOIL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PREPARATION PROCEDURES AND APPLICATIONS
UY29199A1 (en) TIAZOL DERIVATIVES, COMPOSITIONS THAT CONTAIN THEM, PREPARATION PROCEDURES AND APPLICATIONS
UY29875A1 (en) CHEMICAL COMPOUNDS
UY30759A1 (en) CHEMICAL COMPOUNDS
ECSP105253A (en) DERIVATIVES OF 5-PHENYLTIAZOL AND USE AS INHIBITORS OF PI3 CINASA
CR11857A (en) PIRAZOLIC COMPOUNDS 436
UY29767A1 (en) BENZOTIAZOLONAS DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND APPLICATIONS
UY30559A1 (en) DERIVATIVES OF MORFOLINO PIRIMIDINA, PREPARATION PROCESSES, COMPOSITIONS CONTAINING THEM AND APPLICATIONS
UY28572A1 (en) NEW COMPOUNDS
UY30819A1 (en) DERIVATIVES OF PIRAZOL, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PREPARATION PROCESSES AND APPLICATIONS
ECSP056194A (en) DERIVATIVES OF PIRAZOLO-QUINAZOLINA, PROCEDURE FOR ITS PREPARATION AND ITS USE AS QUINASA INHIBITORS
UY31069A1 (en) NEW DERIVATIVES OF IMIDAZOQUINOLA, COMPOSITIONS CONTAINING THEM, PREPARATION PROCESS AND APPLICATIONS
GT200600163A (en) NEW THERAPEUTIC COMBINATIONS FOR THE TREATMENT OR PREVENTION OF DEPRESSION
SV2009003281A (en) ESPIRO KETONA ACETIL-COA CARBOXILASA.0 INHIBITORS.
UY30327A1 (en) NEW COMPOUNDS II
UY29732A1 (en) BENZOTIAZOLONAS DERIVATIVES, PREPARATION PROCESSES, COMPOSITIONS AND COMBINATIONS CONTAINING THEM AND APPLICATIONS
UY29234A1 (en) ADAMANTAN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, BOTH PREPARATION PROCEDURES AND APPLICATIONS.
UY30195A1 (en) DERIVATIVES OF PHENETANOLAMINE, PREPARATION PROCEDURE, COMPOSITIONS CONTAINING THEM AND APPLICATIONS

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160808