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Publication of ECSP014053ApublicationCriticalpatent/ECSP014053A/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Nuevos agonista retinoides selectivos de RAR de la fórmula I: en la que los símbolos tienen os significados definidos en la especificación, y las sales farmacéuticamente activas de los ácidos carboxílicos de la fórmula I, además la invención se refiere al uso de tales agonista receptores de ácido retinoico, en particular a agonista selectivos del receptor y de ácido retinoico (RARy) para el tratamiento del enfisema y de enfermedades pulmonares asociadas, así como la terapia y profilaxis de lesiones epiteliales malignas y premalignas, tumores y alteraciones precancerosas de la membrana mucosa de la boca, lengua, laringe, esófago, vejiga, cuello de la matriz y colon.New RAR selective retinoid agonist of the formula I: in which the symbols have defined meanings in the specification, and the pharmaceutically active salts of the carboxylic acids of the formula I, furthermore the invention relates to the use of such agonist receptors of retinoic acid, in particular selective receptor agonist and retinoic acid (RARy) for the treatment of emphysema and associated lung diseases, as well as the therapy and prophylaxis of malignant and premalignant epithelial lesions, tumors and precancerous alterations of the mucous membrane of the mouth, tongue, larynx, esophagus, bladder, cervix and colon.
EC2001004053A2000-05-022001-05-02
NEW GAMMA SELECTIVE RETINOIDS
ECSP014053A
(en)