ECSP003483A - NEW PHARMACEUTICAL COMBINATIONS FOR HOS INHIBITORS - Google Patents
NEW PHARMACEUTICAL COMBINATIONS FOR HOS INHIBITORSInfo
- Publication number
- ECSP003483A ECSP003483A ECSP003483A ECSP003483A EC SP003483 A ECSP003483 A EC SP003483A EC SP003483 A ECSP003483 A EC SP003483A EC SP003483 A ECSP003483 A EC SP003483A
- Authority
- EC
- Ecuador
- Prior art keywords
- disorders
- sleep
- inhibitors
- disorder
- nos
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a nuevos usos farmacéuticos para compuestos que presentan actividad como inhibidores de la oxido nitrico sintasa (NOS). Específicamente, se refiere al uso de inhibidores de la NOS, particularmente de inhibidores selectivos de la NOS neuronal (nNOS), solos o en combinación con otros agente activo, en particular, en SSRI o un antagonista del receptor NK-1, para el tratamiento de transtornos o afecciones cuyo tratamiento puede realizrse o facilitarse mediante la alteración de los ritmos circadianos. Son ejemplos de tales transtornos y afecciones la ceguera, la obesidad, el transtorno afectivo estacional, el transtorno bipolar, el desfase horario, transtorno de los ritmos circadianos del sueño, privación de sueño, parasomnias, transtornos del sueño REM, hipersomnia, trastornos de los ciclos de suefio-vigila, narcolepsia y trastornos del sueño asociados con el trabajo a turnos con horarios de trabajo irregulares; enuresis nocturna y síndrome de las piernas inquietas.The present invention relates to new pharmaceutical uses for compounds that exhibit activity as inhibitors of nitric oxide synthase (NOS). Specifically, it refers to the use of NOS inhibitors, particularly selective neuronal NOS inhibitors (nNOS), alone or in combination with other active agents, in particular, in SSRI or an NK-1 receptor antagonist, for treatment of disorders or conditions whose treatment can be performed or facilitated by altering circadian rhythms. Examples of such disorders and conditions are blindness, obesity, seasonal affective disorder, bipolar disorder, time lag, disorder of circadian sleep rhythms, sleep deprivation, parasomnias, REM sleep disorders, hypersomnia, disorders of the cycles of sleep-monitoring, narcolepsy and sleep disorders associated with shift work with irregular work schedules; nocturnal enuresis and restless legs syndrome.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003483 ECSP003483A (en) | 2000-05-19 | 2000-05-19 | NEW PHARMACEUTICAL COMBINATIONS FOR HOS INHIBITORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003483 ECSP003483A (en) | 2000-05-19 | 2000-05-19 | NEW PHARMACEUTICAL COMBINATIONS FOR HOS INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003483A true ECSP003483A (en) | 2001-12-28 |
Family
ID=42041109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003483 ECSP003483A (en) | 2000-05-19 | 2000-05-19 | NEW PHARMACEUTICAL COMBINATIONS FOR HOS INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003483A (en) |
-
2000
- 2000-05-19 EC ECSP003483 patent/ECSP003483A/en unknown
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