ECSP003389A - COMPOUNDS AND PROCEDURES FOR THE TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS - Google Patents
COMPOUNDS AND PROCEDURES FOR THE TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERSInfo
- Publication number
- ECSP003389A ECSP003389A ECSP003389A ECSP003389A EC SP003389 A ECSP003389 A EC SP003389A EC SP003389 A ECSP003389 A EC SP003389A EC SP003389 A ECSP003389 A EC SP003389A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- asthma
- substituted
- rhinitis
- allergy
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invnción proporciona compuestos de piperazinas 1,4 sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas. Los compuestos de la invención son moléculas suplentes inhibidoras duales teniendo ambos de inhibición de los leucotrienos, asi como propiedades antihistamínicas. Los compuestos de la invención son útiles para tratar trastornos en los que es posible que se presente un componente histamínico y/o leucotrieno. Estos trastornos incluyen preferiblemente asma, rinitis alérgica estacional y permanente, sinusitis, conjuntivitis, alergia a alimentos, intoxicación escombroide, psoriasis, urticaria, prurito, eccema, artritis reumatoide, enfermedad inflamatoria del intestino, enfermedad pulmonar obstructiva crónica, enfermedad trombótica y otitis media. También se proporcionan procedimientos de tratamiento del asma y la rinitis, administrando a un sujeto que lo necesite una cantidad de los compuestos, eficaz para aliviar el asma y la rinitis.The present invention provides compounds of 1,4-substituted piperazines, 1,4-substituted piperidines and 1-substituted 4-alkylidenylpiperidines. The compounds of the invention are dual inhibitory substitute molecules both having leukotriene inhibition as well as antihistamine properties. The compounds of the invention are useful for treating disorders in which a histamine and / or leukotriene component may be present. These disorders preferably include asthma, seasonal and permanent allergic rhinitis, sinusitis, conjunctivitis, food allergy, scombroid poisoning, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, chronic obstructive pulmonary disease, thrombotic disease, and otitis media. Asthma and rhinitis treatment procedures are also provided, administering to a subject in need an amount of the compounds effective in alleviating asthma and rhinitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003389 ECSP003389A (en) | 2000-03-21 | 2000-03-21 | COMPOUNDS AND PROCEDURES FOR THE TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003389 ECSP003389A (en) | 2000-03-21 | 2000-03-21 | COMPOUNDS AND PROCEDURES FOR THE TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003389A true ECSP003389A (en) | 2000-07-21 |
Family
ID=42041019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003389 ECSP003389A (en) | 2000-03-21 | 2000-03-21 | COMPOUNDS AND PROCEDURES FOR THE TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003389A (en) |
-
2000
- 2000-03-21 EC ECSP003389 patent/ECSP003389A/en unknown
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