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Application filed by Фейнз Терапьютикс, Инк.filedCriticalФейнз Терапьютикс, Инк.
Priority claimed from PCT/US2020/024432external-prioritypatent/WO2020205331A1/en
Publication of EA202192638A1publicationCriticalpatent/EA202192638A1/en
Medicines Containing Material From Animals Or Micro-Organisms
(AREA)
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Abstract
Описаны химерные антигенные рецепторы (CAR), специфичные к CLDN 18.2, векторы, кодирующие CLDN 18.2 CAR, рекомбинантные клетки-хозяева, содержащие CLDN 18.2 CAR (CAR-T или CAR-NK) и способы применения CAR-T или CAR-NK для лечения заболевания, ассоциированного с экспрессией CLDN 18.2.Chimeric antigen receptors (CARs) specific for CLDN 18.2, vectors encoding CLDN 18.2 CARs, recombinant host cells containing CLDN 18.2 CARs (CAR-T or CAR-NK) and methods of using CAR-T or CAR-NK for treatment are described. disease associated with CLDN expression 18.2.
EA202192638A2019-09-062020-03-24
HUMANIZED ANTI-CLAUDIN 18.2 CHIMERIC ANTIGEN RECEPTORS AND THEIR APPLICATIONS
EA202192638A1
(en)