EA202190898A2 - NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER - Google Patents

NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER

Info

Publication number
EA202190898A2
EA202190898A2 EA202190898A EA202190898A EA202190898A2 EA 202190898 A2 EA202190898 A2 EA 202190898A2 EA 202190898 A EA202190898 A EA 202190898A EA 202190898 A EA202190898 A EA 202190898A EA 202190898 A2 EA202190898 A2 EA 202190898A2
Authority
EA
Eurasian Patent Office
Prior art keywords
peptides
cancer
cells
present
tumor
Prior art date
Application number
EA202190898A
Other languages
Russian (ru)
Other versions
EA202190898A3 (en
Inventor
Тони Вайншенк
Йенс Фритше
Харприт Сингх
Андреа Мар
Мартина Отт
Клаудиа Вагнер
Оливер Шор
Original Assignee
Имматикс Байотекнолоджиз Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA202190898A2 publication Critical patent/EA202190898A2/en
Publication of EA202190898A3 publication Critical patent/EA202190898A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам Т-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать Т-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (MHC), или пептиды в отдельности могут быть также мишенями антител, растворимых Т-клеточных рецепторов и других связывающих молекул.The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated peptide epitopes of T cells, alone or in combination with other tumor-associated peptides, which can, for example, serve as active pharmaceutical ingredients in vaccine compositions that stimulate anti-tumor immune responses, or stimulate T cells ex vivo with their transfer to the patient's body. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides alone, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

EA202190898A 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER EA202190898A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562134253P 2015-03-17 2015-03-17

Publications (2)

Publication Number Publication Date
EA202190898A2 true EA202190898A2 (en) 2021-07-30
EA202190898A3 EA202190898A3 (en) 2021-10-29

Family

ID=59256519

Family Applications (4)

Application Number Title Priority Date Filing Date
EA201990755A EA201990755A1 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR APPLICATION IN THE IMMUNOTHERAPY OF Pancreatic Cancer and Other Cancer Species
EA202190897A EA202190897A3 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER
EA202190898A EA202190898A3 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER
EA202190896A EA202190896A3 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EA201990755A EA201990755A1 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR APPLICATION IN THE IMMUNOTHERAPY OF Pancreatic Cancer and Other Cancer Species
EA202190897A EA202190897A3 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA202190896A EA202190896A3 (en) 2015-03-17 2016-03-17 NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF PANCREAS CANCER AND OTHER TYPES OF CANCER

Country Status (2)

Country Link
AR (2) AR103962A1 (en)
EA (4) EA201990755A1 (en)

Also Published As

Publication number Publication date
EA202190898A3 (en) 2021-10-29
EA201990755A1 (en) 2019-08-30
AR122383A2 (en) 2022-09-07
AR103962A1 (en) 2017-06-14
EA202190896A3 (en) 2021-10-29
EA202190896A2 (en) 2021-07-30
EA202190897A2 (en) 2021-07-30
EA202190897A3 (en) 2021-10-29

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