EA202190465A2 - NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY NHL AND OTHER TYPES OF CANCER - Google Patents

NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY NHL AND OTHER TYPES OF CANCER

Info

Publication number
EA202190465A2
EA202190465A2 EA202190465A EA202190465A EA202190465A2 EA 202190465 A2 EA202190465 A2 EA 202190465A2 EA 202190465 A EA202190465 A EA 202190465A EA 202190465 A EA202190465 A EA 202190465A EA 202190465 A2 EA202190465 A2 EA 202190465A2
Authority
EA
Eurasian Patent Office
Prior art keywords
peptides
cells
present
tumor
immunotherapy
Prior art date
Application number
EA202190465A
Other languages
Russian (ru)
Other versions
EA202190465A3 (en
Inventor
Оливер Шор
Андреа Мар
Тони Вайншенк
Анита Вибе
Дженс Фрицше
Харприт Сингх
Original Assignee
Имматикс Байотекнолоджиз Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA202190465A2 publication Critical patent/EA202190465A2/en
Publication of EA202190465A3 publication Critical patent/EA202190465A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Abstract

Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам Т-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать Т-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (MHC), или пептиды в отдельности могут быть также мишенями антител, растворимых Т-клеточных рецепторов и других связывающих молекул.The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated peptide epitopes of T cells, alone or in combination with other tumor-associated peptides, which can, for example, serve as active pharmaceutical ingredients in vaccine compositions that stimulate anti-tumor immune responses, or stimulate T cells ex vivo with their transfer to the patient's body. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides alone, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

EA202190465A 2016-02-19 2017-02-17 NEW PEPTIDES AND PEPTIDE COMBINATIONS FOR USE IN NHL IMMUNOTHERAPY AND OTHER CANCER EA202190465A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662297495P 2016-02-19 2016-02-19

Publications (2)

Publication Number Publication Date
EA202190465A2 true EA202190465A2 (en) 2021-06-30
EA202190465A3 EA202190465A3 (en) 2022-01-31

Family

ID=62596942

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202190465A EA202190465A3 (en) 2016-02-19 2017-02-17 NEW PEPTIDES AND PEPTIDE COMBINATIONS FOR USE IN NHL IMMUNOTHERAPY AND OTHER CANCER

Country Status (2)

Country Link
AR (1) AR107663A1 (en)
EA (1) EA202190465A3 (en)

Also Published As

Publication number Publication date
EA202190465A3 (en) 2022-01-31
AR107663A1 (en) 2018-05-23

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