EA202090814A1 - Способы и композиции для лечения буллезного эпидермолиза - Google Patents

Способы и композиции для лечения буллезного эпидермолиза

Info

Publication number
EA202090814A1
EA202090814A1 EA202090814A EA202090814A EA202090814A1 EA 202090814 A1 EA202090814 A1 EA 202090814A1 EA 202090814 A EA202090814 A EA 202090814A EA 202090814 A EA202090814 A EA 202090814A EA 202090814 A1 EA202090814 A1 EA 202090814A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
compositions
ballous
epidermolysis
treatment
Prior art date
Application number
EA202090814A
Other languages
English (en)
Inventor
Евангелос В. Бадиавас
Original Assignee
Юниверсити Оф Майами
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/712,294 external-priority patent/US20180104186A1/en
Application filed by Юниверсити Оф Майами filed Critical Юниверсити Оф Майами
Publication of EA202090814A1 publication Critical patent/EA202090814A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Water Treatments (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

В настоящем изобретении предложены композиции и способы для лечения буллезного эпидермолиза.
EA202090814A 2017-09-22 2018-09-21 Способы и композиции для лечения буллезного эпидермолиза EA202090814A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/712,294 US20180104186A1 (en) 2013-03-13 2017-09-22 Methods and compositions for the treatment of epidermolysis bullosa
PCT/US2018/052213 WO2019060719A1 (en) 2017-09-22 2018-09-21 METHODS AND COMPOSITIONS FOR THE TREATMENT OF BULLETIN EPIDERMOLYSIS

Publications (1)

Publication Number Publication Date
EA202090814A1 true EA202090814A1 (ru) 2020-08-07

Family

ID=65810503

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090814A EA202090814A1 (ru) 2017-09-22 2018-09-21 Способы и композиции для лечения буллезного эпидермолиза

Country Status (10)

Country Link
EP (1) EP3684336A4 (ru)
JP (1) JP7525396B2 (ru)
KR (1) KR20200088799A (ru)
CN (1) CN111182890A (ru)
AU (1) AU2018335788B2 (ru)
CA (1) CA3076610A1 (ru)
EA (1) EA202090814A1 (ru)
IL (1) IL273407A (ru)
MX (2) MX2020002777A (ru)
WO (1) WO2019060719A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10640464B2 (en) 2011-01-03 2020-05-05 The William M. Yarbrough Foundation Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases
KR102125567B1 (ko) * 2019-07-02 2020-06-22 한양대학교 에리카산학협력단 식물 엑소좀의 대량 생산 방법
AU2020459825A1 (en) * 2020-07-22 2023-03-16 Osaka University Therapeutic agent for dystrophic epidermolysis bullosa
IL300393A (en) * 2020-08-21 2023-04-01 Univ Miami Preparations and treatment methods using microvesicles from mesenchymal stem cells derived from bone marrow
EP3971440B1 (en) 2020-09-21 2023-12-27 Brembo S.p.A. Braking band of a disc brake disc and disc brake disc
WO2023018891A1 (en) * 2021-08-12 2023-02-16 Onconova Therapeutics, Inc. Methods and compositions for treating cancer
US20230114217A1 (en) * 2021-10-12 2023-04-13 Eliksa Therapeutics, Inc. Methods of treating epidermolysis bullosa with cell-free amniotic fluid compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2972193B1 (en) * 2013-03-13 2019-12-18 University Of Miami Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids
WO2015038075A1 (en) * 2013-09-16 2015-03-19 Agency For Science, Technology And Research Method
WO2015138878A1 (en) * 2014-03-13 2015-09-17 Research Institute At Nationwide Children's Hospital, Inc. Methods of delivering heparin binding epidermal growth factor using stem cell generated exosomes
WO2016172598A1 (en) * 2015-04-22 2016-10-27 The Broad Institute Inc. Exosomes and uses thereof
CN108699519A (zh) * 2016-01-12 2018-10-23 康干细胞生物技术有限公司 干细胞衍生的含有大量生长因子的外来体
EP3922253A1 (en) * 2016-01-15 2021-12-15 Orbsen Therapeutics Limited Sdc-2 exosome compositions and methods of isolation and use

Also Published As

Publication number Publication date
AU2018335788A1 (en) 2020-03-19
EP3684336A4 (en) 2021-06-02
IL273407A (en) 2020-05-31
EP3684336A1 (en) 2020-07-29
MX2022015753A (es) 2023-01-19
KR20200088799A (ko) 2020-07-23
CA3076610A1 (en) 2019-03-28
JP7525396B2 (ja) 2024-07-30
CN111182890A (zh) 2020-05-19
AU2018335788B2 (en) 2024-08-15
JP2020534344A (ja) 2020-11-26
MX2020002777A (es) 2020-09-17
WO2019060719A1 (en) 2019-03-28

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