EA202090091A1 - Соль (ss)-аденозилметионина с гексафосфатом инозитола и способ ее получения - Google Patents

Соль (ss)-аденозилметионина с гексафосфатом инозитола и способ ее получения

Info

Publication number
EA202090091A1
EA202090091A1 EA202090091A EA202090091A EA202090091A1 EA 202090091 A1 EA202090091 A1 EA 202090091A1 EA 202090091 A EA202090091 A EA 202090091A EA 202090091 A EA202090091 A EA 202090091A EA 202090091 A1 EA202090091 A1 EA 202090091A1
Authority
EA
Eurasian Patent Office
Prior art keywords
salt
adenosylmethyonin
production
inositol hexaphosphate
inositol
Prior art date
Application number
EA202090091A
Other languages
English (en)
Inventor
Ауро Роберто Тальяни
Даниэле Грегори
Давиде Бьянки
Марко Берна
Федерика Кольцани
Original Assignee
Гносис С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гносис С.п.А. filed Critical Гносис С.п.А.
Publication of EA202090091A1 publication Critical patent/EA202090091A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение относится к соли (SS)-аденозилметионина с мио-инозитол-1,2,3,4,5,6-гексакисфосфатом и к фармацевтическим, нутрицевтическим или ветеринарным композициям, содержащим ее.
EA202090091A 2017-07-04 2018-07-03 Соль (ss)-аденозилметионина с гексафосфатом инозитола и способ ее получения EA202090091A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102017000074957A IT201700074957A1 (it) 2017-07-04 2017-07-04 Sale di (ss)-adenosil metionina con inositolo esafosfato e procedimento per ottenerlo
PCT/EP2018/067882 WO2019007929A1 (en) 2017-07-04 2018-07-03 (SS) -ADENOSYL METHIONINE SALT WITH INOSITOL HEXAPHOSPHATE, AND PROCESS FOR PREPARING SAME

Publications (1)

Publication Number Publication Date
EA202090091A1 true EA202090091A1 (ru) 2020-06-02

Family

ID=60202351

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090091A EA202090091A1 (ru) 2017-07-04 2018-07-03 Соль (ss)-аденозилметионина с гексафосфатом инозитола и способ ее получения

Country Status (13)

Country Link
US (2) US20190010182A1 (ru)
EP (1) EP3648770A1 (ru)
JP (1) JP2020525535A (ru)
KR (1) KR20200024288A (ru)
CN (1) CN110944642A (ru)
AU (1) AU2018298404A1 (ru)
BR (1) BR112020000153A2 (ru)
CA (1) CA3068771A1 (ru)
EA (1) EA202090091A1 (ru)
IL (1) IL271791A (ru)
IT (1) IT201700074957A1 (ru)
PH (1) PH12020500022A1 (ru)
WO (1) WO2019007929A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11633416B1 (en) 2020-03-06 2023-04-25 Arcus Biosciences, Inc. Oral formulations of CD73 compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200589B (it) 1985-02-14 1989-01-27 Gibipharma Spa Derivati naturali attivita farmagologica
DE19931999B4 (de) 1999-07-09 2004-10-28 Leuze Electronic Gmbh + Co Kg Anordnung von Barcodelesegeräten in einem Bussystem
IT1318535B1 (it) * 2000-05-25 2003-08-27 Chementecno Srl Processo per la preparazione di sali farmaceuticamente accettabili di(ss,rs)-s-adenosil-l-metionina.
ITRM20050344A1 (it) 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
ITMI20060026A1 (it) 2006-01-10 2007-07-11 Truffini & Regge Farmaceutici Srl Composizioni per uso rale a base di s-adenosilmetionina e processo per il loro ottenimento
ITMI20071374A1 (it) * 2007-07-10 2009-01-11 Gnosis Spa Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
JPWO2012035685A1 (ja) * 2010-09-13 2014-01-20 磐田化学工業株式会社 ヒアルロン酸産生促進用組成物
KR101645619B1 (ko) 2011-08-12 2016-08-05 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 보존안정성이 우수한 s-아데노실-l-메티오닌 함유 조성물
ES2824807T3 (es) 2013-01-16 2021-05-13 Hebert Sam E Llc Sales de indol-3-propionato estables de S-adenosil-L-metionina
ITMI20131906A1 (it) * 2013-11-18 2015-05-19 Gnosis Spa Composizioni solide orali a lento rilascio
US20170027976A1 (en) * 2014-04-14 2017-02-02 Methylation Sciences International Srl Novel ademetionine formulations

Also Published As

Publication number Publication date
WO2019007929A1 (en) 2019-01-10
JP2020525535A (ja) 2020-08-27
PH12020500022A1 (en) 2020-10-12
CA3068771A1 (en) 2019-01-10
IT201700074957A1 (it) 2019-01-04
EP3648770A1 (en) 2020-05-13
BR112020000153A2 (pt) 2020-07-14
AU2018298404A1 (en) 2020-02-06
IL271791A (en) 2020-02-27
US20200165287A1 (en) 2020-05-28
CN110944642A (zh) 2020-03-31
KR20200024288A (ko) 2020-03-06
US20190010182A1 (en) 2019-01-10

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