EA201992857A1 - Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде - Google Patents

Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде

Info

Publication number
EA201992857A1
EA201992857A1 EA201992857A EA201992857A EA201992857A1 EA 201992857 A1 EA201992857 A1 EA 201992857A1 EA 201992857 A EA201992857 A EA 201992857A EA 201992857 A EA201992857 A EA 201992857A EA 201992857 A1 EA201992857 A1 EA 201992857A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
fluid
devices
destructive detection
unsolved particles
Prior art date
Application number
EA201992857A
Other languages
English (en)
Other versions
EA038813B1 (ru
Inventor
Грэхам Ф. Милн
Эрвин Фройнд
Райан Л. Смит
Original Assignee
Амген Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Амген Инк. filed Critical Амген Инк.
Publication of EA201992857A1 publication Critical patent/EA201992857A1/ru
Publication of EA038813B1 publication Critical patent/EA038813B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9036—Investigating the presence of flaws or contamination in a container or its contents using arrays of emitters or receivers
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Dispersion Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Установки, способы и компьютерные программные продукты, раскрытые в настоящем изобретении, могут быть использованы для неразрушающего обнаружения нерастворенных частей, таких как осколки стекла и/или белковые агрегаты, в текучей среде, находящейся в сосуде, такой как, без ограничения, жидкость, содержащая лекарственное средство.
EA201992857A 2012-08-20 2012-08-29 Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде EA038813B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261691211P 2012-08-20 2012-08-20

Publications (2)

Publication Number Publication Date
EA201992857A1 true EA201992857A1 (ru) 2020-06-30
EA038813B1 EA038813B1 (ru) 2021-10-22

Family

ID=71138801

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201992857A EA038813B1 (ru) 2012-08-20 2012-08-29 Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде
EA202192044A EA202192044A3 (ru) 2012-08-20 2012-08-29 Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA202192044A EA202192044A3 (ru) 2012-08-20 2012-08-29 Способы и устройства для неразрушающего обнаружения нерастворенных частиц в текучей среде

Country Status (1)

Country Link
EA (2) EA038813B1 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022229841A1 (en) * 2021-04-28 2022-11-03 Stevanato Group S.P.A. Apparatus and method for inspecting containers which are at least partially transparent to a predetermined electromagnetic radiation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024052440A1 (en) * 2022-09-09 2024-03-14 F. Hoffmann-La Roche Ag Inspection system and method for a closed medical container

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02159539A (ja) * 1988-12-14 1990-06-19 Toshiba Corp 浄水場のフロック画像撮影装置
US5905568A (en) * 1997-12-15 1999-05-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Stereo imaging velocimetry
JP2002267612A (ja) * 2001-03-13 2002-09-18 Hitachi Eng Co Ltd 透明容器等の充填液体中の異物検査装置及びシステム
JP4152650B2 (ja) * 2002-03-18 2008-09-17 セファテクノロジー株式会社 液体試料の沈降速度測定装置および沈降速度測定方法
JP4048848B2 (ja) * 2002-06-28 2008-02-20 株式会社日立プラントテクノロジー 容器内異物検出装置および容器内異物検出方法
EP1779096B1 (en) * 2004-07-30 2013-07-31 Eagle Vision Systems B.V. Apparatus and method for checking of containers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022229841A1 (en) * 2021-04-28 2022-11-03 Stevanato Group S.P.A. Apparatus and method for inspecting containers which are at least partially transparent to a predetermined electromagnetic radiation
US11815469B2 (en) 2021-04-28 2023-11-14 Stevanato Group S.P.A. Apparatus and method for inspecting containers which are at least partially transparent to a predetermined electromagnetic radiation

Also Published As

Publication number Publication date
EA038813B1 (ru) 2021-10-22
EA202192044A3 (ru) 2022-03-31
EA202192044A2 (ru) 2021-11-30

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FR3015052B1 (fr) Procede et dispositif pour mesurer une signature de source