EA201990695A1 - 7-SUBSTITUTED 1-Aryl-Naphthyridine-3-Amides of Carboxylic Acids and Their Use - Google Patents

7-SUBSTITUTED 1-Aryl-Naphthyridine-3-Amides of Carboxylic Acids and Their Use

Info

Publication number
EA201990695A1
EA201990695A1 EA201990695A EA201990695A EA201990695A1 EA 201990695 A1 EA201990695 A1 EA 201990695A1 EA 201990695 A EA201990695 A EA 201990695A EA 201990695 A EA201990695 A EA 201990695A EA 201990695 A1 EA201990695 A1 EA 201990695A1
Authority
EA
Eurasian Patent Office
Prior art keywords
naphthyridine
amides
aryl
substituted
carboxylic acids
Prior art date
Application number
EA201990695A
Other languages
Russian (ru)
Other versions
EA038451B1 (en
Inventor
Хенрик Теллер
Александрос Факалопоулос
Мелисса Боультадакис Арапинис
Александр Штрауб
Ханна Тинель
Маркус Брехманн
Маттиас Беат Виттвер
Максимилиан Андреас Кульманн
Тиль Фройденбергер
Томас Мондритцки
Тобиас Марквардт
Original Assignee
Байер Акциенгезельшафт
Байер Фарма Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байер Акциенгезельшафт, Байер Фарма Акциенгезельшафт filed Critical Байер Акциенгезельшафт
Priority claimed from PCT/EP2017/072339 external-priority patent/WO2018050510A1/en
Publication of EA201990695A1 publication Critical patent/EA201990695A1/en
Publication of EA038451B1 publication Critical patent/EA038451B1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Настоящая заявка касается новых 7-замещенных 1-арил-нафтиридин-3-амидов карбоновых кислот, способов их получения, их применения отдельно или в комбинациях для лечения и/или профилактики заболеваний, а также их применения для изготовления лекарственных средств для лечения и/или профилактики заболеваний, в частности для лечения и/или профилактики сердечно-сосудистых заболеваний и/или заболеваний почек.This application relates to new 7-substituted 1-aryl-naphthyridine-3-amides of carboxylic acids, methods for their preparation, their use separately or in combinations for the treatment and / or prevention of diseases, as well as their use for the manufacture of medicines for the treatment and / or disease prevention, in particular for the treatment and / or prevention of cardiovascular disease and / or kidney disease.

EA201990695A 2016-12-06 2017-09-06 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof EA038451B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16202509 2016-12-06
PCT/EP2017/072339 WO2018050510A1 (en) 2016-09-14 2017-09-06 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof

Publications (2)

Publication Number Publication Date
EA201990695A1 true EA201990695A1 (en) 2019-08-30
EA038451B1 EA038451B1 (en) 2021-08-30

Family

ID=57517759

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201990695A EA038451B1 (en) 2016-12-06 2017-09-06 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof

Country Status (2)

Country Link
EA (1) EA038451B1 (en)
PT (1) PT3512849T (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
JP2758722B2 (en) * 1993-08-13 1998-05-28 ドング ホワ ファーマシューチカル インダストリアル カンパニー，リミテッド New quinolone carboxylic acid derivatives
WO2005026165A1 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
CA2548009A1 (en) * 2003-12-09 2005-06-23 Vertex Pharmaceuticals Incorporated Naphthyridine derivatives and their use as modulators of muscarinic receptors
WO2010093341A1 (en) * 2009-02-10 2010-08-19 Janssen Pharmaceutica N.V. C-7 isoxazolinyl quinolone/naphthyridine derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
PT3512849T (en) 2021-09-08
EA038451B1 (en) 2021-08-30

Similar Documents

Publication Publication Date Title
EA201890111A1 (en) SUBSTITUTED OXOPYRIDINE DERIVATIVES
EA201591616A1 (en) TRIFTTOROMETHYL-SUBSTITUTED ANNELATED PYRIMIDINES AND THEIR APPLICATION
JOP20200192A1 (en) Anti-tigit antibodies
EA201291336A1 (en) SUBSTITUTED 5-FLUOR-1H-PYRAZOLOPIRIDINE AND THEIR APPLICATION
EA201290836A1 (en) RELATED BIS-ARYL ARYLTRIAZOLONES AND THEIR APPLICATION
EA201792354A1 (en) BATCHOLEIC ACID COMPOSITIONS AND METHODS OF APPLICATION
EA201790377A1 (en) ANTIBODIES TO GLUCAGON AND THEIR APPLICATIONS
EA201590251A1 (en) NEW 5-AMINOTETRAHYDROHINOLIN-2-CARBONIC ACIDS AND THEIR APPLICATION
EA201890725A1 (en) PHARNESIDE X-RECEPTOR AGONISTS AND THEIR APPLICATION
EA201490546A1 (en) SUBSTITUTED ANNELED PYRIMIDINES AND THEIR APPLICATION
WO2017030823A3 (en) Anti-tigit antibodies
EA201890453A1 (en) ANTI-ANGPTL8 ANTIBODIES AND THEIR APPLICATION
EA201491339A1 (en) SUBSTITUTED ANNELLATED PYRIMIDINES AND TRIAZINES AND THEIR APPLICATION
EA201300669A1 (en) SUBSTITUTED 1-BENZYL CYCLOALKYL CARBONIC ACIDS AND THEIR APPLICATION
EA201291034A1 (en) APTAMERS TO β-NGF AND THEIR APPLICATION IN THE TREATMENT OF B-NGF-MEDIATED DISEASES AND DISORDERS
EA201790273A1 (en) FLAGELLIN COMPOSITIONS AND THEIR APPLICATION
EA201590343A1 (en) ALKYLPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES
EA201691582A1 (en) NEW PHARMACEUTICAL PREPARATIONS
EA201791516A1 (en) METHODS OF COMBINED TREATMENT OF MALIGNANT TUMORS
EA201890002A1 (en) POSITIVE ALLOSTERIC MODULATORS OF MUSCARINE M2 RECEPTOR
EA202191764A1 (en) SUBSTITUTED OXOPYRIDINE DERIVATIVES
EA201600288A1 (en) SUBSTITUTED PHYLALANINE DERIVATIVES
EA201600096A1 (en) BENZYL-1H-PYRAZOL [3,4-B] Pyridine and their use
EA202091020A1 (en) SUBSTITUTED IMIDAZOPYRIDINAMIDES AND THEIR APPLICATION
CY1124492T1 (en) 7-Substituted 1-aryl-naphthyridine-3-carboxamides and their use

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ KG TJ TM

TH4A Publication of the corrected specification to eurasian patent