EA201892777A1 - Обнаружение микроскопических объектов в текучей среде - Google Patents

Обнаружение микроскопических объектов в текучей среде

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Publication number
EA201892777A1
EA201892777A1 EA201892777A EA201892777A EA201892777A1 EA 201892777 A1 EA201892777 A1 EA 201892777A1 EA 201892777 A EA201892777 A EA 201892777A EA 201892777 A EA201892777 A EA 201892777A EA 201892777 A1 EA201892777 A1 EA 201892777A1
Authority
EA
Eurasian Patent Office
Prior art keywords
processed
filtered
image data
holographic
microscopic
Prior art date
Application number
EA201892777A
Other languages
English (en)
Other versions
EA037743B1 (ru
Inventor
Теро Кести
Эса Хямяляйнен
Original Assignee
Уватер Ой
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Уватер Ой filed Critical Уватер Ой
Publication of EA201892777A1 publication Critical patent/EA201892777A1/ru
Publication of EA037743B1 publication Critical patent/EA037743B1/ru

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Classifications

    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453—Holographic interferometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/85—Investigating moving fluids or granular solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G01N2015/0233—Investigating particle size or size distribution by optical means using imaging; using holography using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1029—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/103—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0378—Shapes
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005—Adaptation of holography to specific applications
    • G03H2001/0033—Adaptation of holography to specific applications in hologrammetry for measuring or analysing
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005—Adaptation of holography to specific applications
    • G03H2001/0033—Adaptation of holography to specific applications in hologrammetry for measuring or analysing
    • G03H2001/0044—Adaptation of holography to specific applications in hologrammetry for measuring or analysing holographic fringes deformations; holographic sensors
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
    • G03H2001/0447—In-line recording arrangement

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Holo Graphy (AREA)
  • Image Processing (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

Способ (10) включает получение (101) обработанных данных изображения, захваченных датчиком изображения, который принимает свет, прошедший через пробный объем, содержащий текучую среду, которая, возможно, содержит инородные микроскопические объекты, при освещении пробного объема когерентным светом, при этом обработанные данные изображения содержат для микроскопического объекта обработанную голографическую картину с обработанной пространственно меняющейся интенсивностью, сформированную интерференционными полосами; создание (102) фильтрованных данных изображения, включающее автоматическое фильтрование обработанных данных изображения фильтром усиления контуров, при этом фильтрованные данные изображения содержат для обработанной голографической картины фильтрованную голографическую картину; и автоматическое обнаружение (103) на основе фильтрованной голографической картины присутствия микроскопического объекта, ассоциированного с фильтрованной голографической картиной, в пробном объеме текучей среды.
EA201892777A 2016-06-22 2017-06-21 Обнаружение микроскопических объектов в текучей среде EA037743B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16175687.9A EP3260841B1 (en) 2016-06-22 2016-06-22 Detecting microscopic objects in fluids
PCT/FI2017/050463 WO2017220860A1 (en) 2016-06-22 2017-06-21 Detecting microscopic objects in fluids

Publications (2)

Publication Number Publication Date
EA201892777A1 true EA201892777A1 (ru) 2019-06-28
EA037743B1 EA037743B1 (ru) 2021-05-17

Family

ID=56203200

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892777A EA037743B1 (ru) 2016-06-22 2017-06-21 Обнаружение микроскопических объектов в текучей среде

Country Status (10)

Country Link
US (1) US11630420B2 (ru)
EP (1) EP3260841B1 (ru)
KR (1) KR102402198B1 (ru)
CN (1) CN109477782A (ru)
AU (1) AU2017281680B2 (ru)
CA (1) CA3027810A1 (ru)
EA (1) EA037743B1 (ru)
SG (1) SG11201811309YA (ru)
WO (1) WO2017220860A1 (ru)
ZA (1) ZA201900411B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108489872B (zh) * 2018-03-23 2022-03-04 奥星制药设备（石家庄）有限公司 在线粒度监测方法和系统
EP3575773A1 (en) * 2018-05-28 2019-12-04 Universität für Bodenkultur Wien A method for determining a three-dimensional particle distribution in a medium
WO2021011637A1 (en) * 2019-07-15 2021-01-21 Arizona Board Of Regents On Behalf Of The University Of Arizona Complex diversity for accurate phase retrieval with single-shot acquisition
CN116026729B (zh) * 2023-03-03 2024-03-15 浙江大学 一种基于数字同轴全息显微的便携式微塑料检测装置
CN116071689B (zh) * 2023-03-07 2023-06-06 四川三思德科技有限公司 一种基于lora技术的水源地水质在线监测方法及系统
CN117233116B (zh) * 2023-11-09 2024-02-02 江西鼎智检测有限公司 一种基于机器视觉的水质分析方法及系统

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6876474B2 (en) 2002-11-27 2005-04-05 Dalhousie University Method for tracking particles and life forms in three dimensions and in time
EP1747502A4 (en) * 2004-04-16 2009-05-13 Dce Aprilis Inc CALIBRATION OF HOLOGRAPHIC DATA STORAGE SYSTEMS USING CALIBRATION CHARACTERISTICS OF HOLOGRAPHIC MEDIA
EP2110697B1 (en) * 2008-04-17 2016-02-10 Ruprecht-Karls-Universität Heidelberg Wave field microscope with sub-wavelength resolution and methods for processing microscopic images to detect objects with sub-wavelength dimensions
EP3671176B1 (en) * 2009-10-20 2022-04-13 The Regents of the University of California Incoherent lensfree cell holography and microscopy on a chip
JP2013533469A (ja) * 2010-05-25 2013-08-22 アリックス インク 免疫診断における生物学的および化学的分析および用途における粒子の位置的自由度の検出のための方法および装置
FR3020682B1 (fr) * 2014-04-30 2016-05-27 Commissariat Energie Atomique Procede et systeme de detection d'au moins une particule dans un liquide corporel, et procede associe de diagnostic de la meningite
EP2985719A1 (en) * 2014-08-15 2016-02-17 IMEC vzw A system and method for cell recognition
TWI557462B (zh) * 2014-11-28 2016-11-11 台灣愛美科股份有限公司 自動聚焦系統與方法
KR101820563B1 (ko) * 2014-12-31 2018-01-19 한국전자통신연구원 홀로그램 데이터 포맷과 홀로그래픽 비디오 시스템 장치 및 방법
CN105547945A (zh) * 2016-01-14 2016-05-04 天津大学 干涉粒子成像系统采样区内粒子的判别方法
WO2017201546A1 (en) * 2016-05-20 2017-11-23 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for automated single cell cytological classification in flow

Also Published As

Publication number Publication date
US11630420B2 (en) 2023-04-18
EA037743B1 (ru) 2021-05-17
EP3260841B1 (en) 2024-03-13
WO2017220860A1 (en) 2017-12-28
ZA201900411B (en) 2022-08-31
CN109477782A (zh) 2019-03-15
KR102402198B1 (ko) 2022-05-25
AU2017281680A1 (en) 2019-02-07
EP3260841C0 (en) 2024-03-13
CA3027810A1 (en) 2017-12-28
SG11201811309YA (en) 2019-01-30
AU2017281680B2 (en) 2022-03-17
KR20190022691A (ko) 2019-03-06
EP3260841A1 (en) 2017-12-27
US20190187613A1 (en) 2019-06-20

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