EA201892046A1 - Термопары, содержащие полимерное покрытие, для обнаружения аналитов и связанные способы - Google Patents

Термопары, содержащие полимерное покрытие, для обнаружения аналитов и связанные способы

Info

Publication number
EA201892046A1
EA201892046A1 EA201892046A EA201892046A EA201892046A1 EA 201892046 A1 EA201892046 A1 EA 201892046A1 EA 201892046 A EA201892046 A EA 201892046A EA 201892046 A EA201892046 A EA 201892046A EA 201892046 A1 EA201892046 A1 EA 201892046A1
Authority
EA
Eurasian Patent Office
Prior art keywords
analyte
detection
thermocouple
polymer
analytical polymer
Prior art date
Application number
EA201892046A
Other languages
English (en)
Inventor
Ван Барт Роберт Николас Гринсвен
Томас Ян Клей
Original Assignee
Университейт Маастрихт
Академиш Зикенхёйс Маастрихт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Университейт Маастрихт, Академиш Зикенхёйс Маастрихт filed Critical Университейт Маастрихт
Priority claimed from PCT/EP2016/076572 external-priority patent/WO2017178081A1/en
Publication of EA201892046A1 publication Critical patent/EA201892046A1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00—Investigating or analyzing materials by the use of thermal means
    • G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
    • G01N25/48—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation
    • G01N25/4806—Details not adapted to a particular type of sample
    • G01N25/4813—Details not adapted to a particular type of sample concerning the measuring means
    • G01N25/482—Details not adapted to a particular type of sample concerning the measuring means concerning the temperature responsive elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Combustion & Propulsion (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)

Abstract

Устройство (200) для обнаружения аналита (132) содержит термопару (210), покрытую аналитическим полимером (214). Аналитический полимер составлен так, чтобы связываться с аналитом, а теплофизическое свойство аналитического полимера варьируется в зависимости от количества аналита, связанного с ним. Способ получения сенсора включает нанесение на термопару аналитического полимера в форме покрытия. Способ обнаружения аналита включает пропускание жидкости, содержащей аналит, вблизи термопары, покрытой аналитическим полимером, связывание аналита с аналитическим полимером, определение температуры термопары и расчет концентрации аналита в жидкости по меньшей мере отчасти на основании теплофизического свойства аналитического полимера.
EA201892046A 2016-04-11 2016-11-03 Термопары, содержащие полимерное покрытие, для обнаружения аналитов и связанные способы EA201892046A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/095,653 US10324087B2 (en) 2016-04-11 2016-04-11 Thermocouples comprising a polymer for detecting analytes and related methods
PCT/EP2016/076572 WO2017178081A1 (en) 2016-04-11 2016-11-03 Thermocouples comprising a polymer coating for detecting analytes and related methods

Publications (1)

Publication Number Publication Date
EA201892046A1 true EA201892046A1 (ru) 2019-05-31

Family

ID=59998714

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892046A EA201892046A1 (ru) 2016-04-11 2016-11-03 Термопары, содержащие полимерное покрытие, для обнаружения аналитов и связанные способы

Country Status (2)

Country Link
US (1) US10324087B2 (ru)
EA (1) EA201892046A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10139407B2 (en) 2016-04-11 2018-11-27 Universiteit Maastricht Methods for detecting bacteria using polymer materials
GB2583927A (en) * 2019-05-13 2020-11-18 The Manchester Metropolitan Univ A sensor device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4924037A (en) 1988-12-20 1990-05-08 W. L. Gore & Associates, Inc. Electrical cable
US6161028A (en) 1999-03-10 2000-12-12 Optiscan Biomedical Corporation Method for determining analyte concentration using periodic temperature modulation and phase detection
US20040126814A1 (en) 2000-08-21 2004-07-01 Singh Waheguru Pal Sensor having molecularly imprinted polymers
WO2002099386A2 (en) 2001-06-07 2002-12-12 Proligo Llc Microcalorimetric detection of analytes and binding events
US7141210B2 (en) 2002-04-01 2006-11-28 Palo Alto Research Center Incorporated Apparatus and method for a nanocalorimeter for detecting chemical reactions
EP1608775A1 (en) 2003-03-05 2005-12-28 University of Saskatchewan Technologies Inc. Nucleic acid mismatch detection
US8557182B2 (en) 2003-12-08 2013-10-15 The Research Foundation Of State University Of New York Site selectively tagged and templated molecularly imprinted polymers for sensor applications
JP2005345385A (ja) 2004-06-04 2005-12-15 Rikogaku Shinkokai 特性測定用器具および特性測定方法
WO2007067145A1 (en) 2005-12-07 2007-06-14 Mip Technologies Ab Monodisperse molecularly imprinted polymer beads
WO2010151592A1 (en) 2009-06-23 2010-12-29 Bayer Healthcare Llc System and apparatus for determining temperatures in a fluid analyte system
WO2012076350A1 (en) 2010-12-08 2012-06-14 Imec A biosensor using impedimetric real-time monitoring
EP2772753B1 (en) 2013-02-28 2018-10-03 IMEC vzw Heat-transfer resistance based analysis of bioparticles

Also Published As

Publication number Publication date
US10324087B2 (en) 2019-06-18
US20170292949A1 (en) 2017-10-12

Similar Documents

Publication Publication Date Title
BR112018000851A2 (pt) sistemas e métodos para detecção e quantificação aprimoradas de analitos
BR112017021256A2 (pt) dispositivos e métodos para a análise de amostras
BRPI0814202A2 (pt) Métodos e sistemas de determinação de concentração de produto de análise em amostra fluida e meio legível em computador
MY192493A (en) Urinalysis device and dry reagent for quantitative urinalysis
JP2015514987A5 (ru)
BR112015032560A2 (pt) compensação de temperatura para uma medição de analito determinada a partir de um tempo de amostragem especificado derivado de uma característica física detectada da amostra contendo o analito
SE0800724L (sv) Blodviskositetsanalys
BR112015001936A2 (pt) métodos de predizer um comportamento do fluido no reservatório usando uma equação de estado
BR112016007037A2 (pt) método para detectar câncer pancreático, anticorpo monoclonal e kit
MY183701A (en) Immunochromatographic test piece and immunochromatography method using same
MX2018003326A (es) Dispositivo de deteccion y metodo de deteccion de analitos en muestra liquida.
WO2013155157A8 (en) Method for preheating a sample and for determining fat or moisture content
BR112022011676A2 (pt) Kit para detectar um analito de interesse em uma pluralidade de amostras líquidas biológicas, método para detectá-lo e /ou quantificá-lo e cartucho para realizar tal método
WO2019066572A3 (en) Method and device for analyzing target analyte in sample
CY1125342T1 (el) Μεθοδοι για την ανιχνευση και/ή μετρηση αντισωματων εναντι των αντισωματων φαρμακου, ιδιως αντισωματων εναντι των αντισωματων φαρμακου προκυπτοντων κατα τη θεραπευτικη αγωγη
EA201892046A1 (ru) Термопары, содержащие полимерное покрытие, для обнаружения аналитов и связанные способы
EA201891636A1 (ru) Диагностическое устройство и способ диагностики
ATE426168T1 (de) Verwendung von asc als marker fur kolorektalkarzinome
MX2016007148A (es) Metodos de ensayo de beta-glucano.
DK3207374T3 (da) Fremgangsmåde og system til bestemmelse af koncentrationen af en analyt i en fluidprøve
BR112022002283A2 (pt) Método implementado por computador para integração automática, linha de processamento implementável por computador para integração automática e sistema de espectrometria de massa
MX2015012921A (es) Medicion de temperatura directa de una tira de prueba.
WO2016100117A3 (en) Accurate assay measurement of hydrophobic haptenic analytes
BR112017009309A2 (pt) dispositivo de teste para medir a quantidade de analito em uma amostra fluida, método para fazer um dispositivo de teste para medir a quantidade de analito em uma amostra fluida, e método de utilização de um dispositivo de teste
BR112019007138A2 (pt) método e sistema de análise para testagem de uma amostra