EA201791490A1 - Композиция для осветления кожи, содержащая 4-гексилрезорцин и иломастат - Google Patents
Композиция для осветления кожи, содержащая 4-гексилрезорцин и иломастатInfo
- Publication number
- EA201791490A1 EA201791490A1 EA201791490A EA201791490A EA201791490A1 EA 201791490 A1 EA201791490 A1 EA 201791490A1 EA 201791490 A EA201791490 A EA 201791490A EA 201791490 A EA201791490 A EA 201791490A EA 201791490 A1 EA201791490 A1 EA 201791490A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- skin
- composition
- melanocytes
- hexilresorcin
- ilomastat
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Настоящее изобретение относится к области композиций для личной гигиены, в частности композиций для осветления кожи. Имеется потребность в более эффективном способе снижения содержания меланина в меланоцитах. Было установлено, что 4-гексилрезорцин в комбинации с ингибитором ММР галардином синергетически снижает содержание меланина в меланоцитах. Таким образом, настоящее изобретение относится к композиции, содержащей синергетическую комбинацию 4-гексилрезорцина и галардина, для применения в осветлении кожи. Таким образом, указанная композиция при местном нанесении её в течение соответствующего периода времени в условиях in vivoможет применяться для осветления кожи или для уменьшения возрастных пятен или веснушек.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14200625 | 2014-12-30 | ||
PCT/EP2015/077410 WO2016107697A1 (en) | 2014-12-30 | 2015-11-24 | A skin lightening composition comprising 4-hexylresorcinol and ilomastat |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201791490A1 true EA201791490A1 (ru) | 2017-11-30 |
EA032573B1 EA032573B1 (ru) | 2019-06-28 |
Family
ID=52130170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201791490A EA032573B1 (ru) | 2014-12-30 | 2015-11-24 | Композиция для осветления кожи, содержащая 4-гексилрезорцин и иломастат |
Country Status (9)
Country | Link |
---|---|
US (1) | US10166412B2 (ru) |
EP (1) | EP3240524B1 (ru) |
JP (1) | JP6609317B2 (ru) |
CN (1) | CN107106454B (ru) |
CA (1) | CA2970968C (ru) |
EA (1) | EA032573B1 (ru) |
MX (1) | MX365370B (ru) |
PH (1) | PH12017500996A1 (ru) |
WO (1) | WO2016107697A1 (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018046243A1 (en) * | 2016-09-06 | 2018-03-15 | Unilever N.V. | Compounds for reducing cellular melanin content |
CN110339079B (zh) * | 2019-07-03 | 2022-05-24 | 广州双慧化妆品有限公司 | 包含酰胺衍生物的组合物及其在化妆品中的应用 |
FR3123568B1 (fr) * | 2021-06-03 | 2023-06-09 | Laboratoires M&L | Utilisation cosmetique d’un extrait huileux de dreches d'immortelle comme agent eclaircissant de la peau |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7004933B2 (en) | 1998-05-29 | 2006-02-28 | Light Bioscience L.L.C. | Ultrasound enhancement of percutaneous drug absorption |
US6384081B2 (en) | 1998-10-09 | 2002-05-07 | Charles L. Berman | Treatment of diseases of the eye characterized by the formation of metalloproteinase |
JP5106739B2 (ja) * | 2000-06-29 | 2012-12-26 | クイック−メッド テクノロジーズ、インク. | 化粧品組成物および方法 |
DE10133196A1 (de) | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Nicotinsäure enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
US20040219179A1 (en) | 2002-09-20 | 2004-11-04 | Mcdaniel David H. | Skin abrasive agents |
US20060074108A1 (en) | 2004-10-04 | 2006-04-06 | Bioderm Research | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition |
US8022051B2 (en) | 2004-10-20 | 2011-09-20 | Doosan Corporation | Composition for protection and improvement of skin, or reinforcing skin barrier function comprising phosphatidylserine |
US20060217690A1 (en) | 2005-03-22 | 2006-09-28 | Bastin Norman J | Method for treating various dermatological and muscular conditions using electromagnetic radiation |
US20070225301A1 (en) | 2006-02-13 | 2007-09-27 | Astion Inflammation Aps | Treatment of acne and other diseases |
WO2008079898A1 (en) | 2006-12-20 | 2008-07-03 | Pharmwest, Inc. | Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions |
BRPI0811102A2 (pt) * | 2007-05-15 | 2014-09-23 | Puretech Ventures | Métodos e composições para tratar condições de pele |
WO2009055581A2 (en) | 2007-10-24 | 2009-04-30 | Skintreet, Llc | Method and portable device for treating skin disorders |
JP2009132644A (ja) * | 2007-11-30 | 2009-06-18 | Toyobo Co Ltd | 面皰炎症抑制剤及びこれを含む皮膚外用剤 |
US20090197939A1 (en) | 2008-02-01 | 2009-08-06 | Mary Kay Inc. | Methods of treating skin with aromatic skin-active ingredients |
US20090263513A1 (en) | 2008-04-18 | 2009-10-22 | Jan Marini | Cosmetic skin lightening formulation |
US20100158842A1 (en) * | 2008-10-09 | 2010-06-24 | Spectrum Dynamics Llc | Natural skin whitener: 4-hydroxy-oxindole-3-acetic acid |
FR2937247B1 (fr) | 2008-10-16 | 2010-12-17 | Sederma Sa | Composition cosmetique blanchissante et anti-rougeurs |
AU2009329035A1 (en) | 2008-12-01 | 2011-06-23 | Laila Pharmaceuticals Pvt. Ltd. | Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof |
WO2010087983A1 (en) | 2009-01-29 | 2010-08-05 | Kambiz Thomas Moazed | Method and system for effecting changes in pigmented tissue |
EP2412701B1 (en) * | 2009-03-25 | 2015-08-12 | Ajinomoto Co., Inc. | Novel amide derivative and skin whitening agent |
EP2522331A1 (en) | 2011-05-09 | 2012-11-14 | DSM IP Assets B.V. | Use of resveratrol and niacinamide |
DE102012219573A1 (de) | 2012-10-25 | 2014-04-30 | Bayerische Motoren Werke Aktiengesellschaft | Verfahren zur richtungsabhängigen Signalisierung |
-
2015
- 2015-11-24 EA EA201791490A patent/EA032573B1/ru not_active IP Right Cessation
- 2015-11-24 US US15/539,857 patent/US10166412B2/en active Active
- 2015-11-24 CN CN201580071648.0A patent/CN107106454B/zh active Active
- 2015-11-24 JP JP2017530135A patent/JP6609317B2/ja active Active
- 2015-11-24 MX MX2017008586A patent/MX365370B/es active IP Right Grant
- 2015-11-24 EP EP15798135.8A patent/EP3240524B1/en active Active
- 2015-11-24 CA CA2970968A patent/CA2970968C/en active Active
- 2015-11-24 WO PCT/EP2015/077410 patent/WO2016107697A1/en active Application Filing
-
2017
- 2017-05-29 PH PH12017500996A patent/PH12017500996A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2970968C (en) | 2023-07-11 |
CN107106454A (zh) | 2017-08-29 |
US10166412B2 (en) | 2019-01-01 |
JP2018500306A (ja) | 2018-01-11 |
US20170354835A1 (en) | 2017-12-14 |
CA2970968A1 (en) | 2016-07-07 |
JP6609317B2 (ja) | 2019-11-20 |
CN107106454B (zh) | 2019-12-20 |
MX365370B (es) | 2019-05-31 |
EA032573B1 (ru) | 2019-06-28 |
PH12017500996A1 (en) | 2017-12-18 |
EP3240524A1 (en) | 2017-11-08 |
EP3240524B1 (en) | 2020-01-01 |
WO2016107697A1 (en) | 2016-07-07 |
MX2017008586A (es) | 2017-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |
|
PC4A | Registration of transfer of a eurasian patent by assignment |