EA201690107A1 - Фармацевтическая композиция, содержащая диметилфумарат, для введения в низкой суточной дозе - Google Patents
Фармацевтическая композиция, содержащая диметилфумарат, для введения в низкой суточной дозеInfo
- Publication number
- EA201690107A1 EA201690107A1 EA201690107A EA201690107A EA201690107A1 EA 201690107 A1 EA201690107 A1 EA 201690107A1 EA 201690107 A EA201690107 A EA 201690107A EA 201690107 A EA201690107 A EA 201690107A EA 201690107 A1 EA201690107 A1 EA 201690107A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmaceutical composition
- daily dose
- dimethylfumate
- introduction
- composition containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- LDCRTTXIJACKKU-ONEGZZNKSA-N dimethyl fumarate Chemical compound COC(=O)\C=C\C(=O)OC LDCRTTXIJACKKU-ONEGZZNKSA-N 0.000 abstract 3
- 229960004419 dimethyl fumarate Drugs 0.000 abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361870096P | 2013-08-26 | 2013-08-26 | |
| EP13181735 | 2013-08-26 | ||
| US201361895740P | 2013-10-25 | 2013-10-25 | |
| EP13190304 | 2013-10-25 | ||
| US201462035898P | 2014-08-11 | 2014-08-11 | |
| EP14180569 | 2014-08-11 | ||
| PCT/EP2014/068094 WO2015028472A1 (en) | 2013-08-26 | 2014-08-26 | Pharmaceutical composition containing dimethyl fumarate for administration at a low daily dose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201690107A1 true EA201690107A1 (ru) | 2016-10-31 |
Family
ID=52585633
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201690107A EA201690107A1 (ru) | 2013-08-26 | 2014-08-26 | Фармацевтическая композиция, содержащая диметилфумарат, для введения в низкой суточной дозе |
| EA201690102A EA201690102A1 (ru) | 2013-08-26 | 2014-08-26 | Фармацевтическая композиция, содержащая диметилфумарат, для введения в низкой суточной дозе |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201690102A EA201690102A1 (ru) | 2013-08-26 | 2014-08-26 | Фармацевтическая композиция, содержащая диметилфумарат, для введения в низкой суточной дозе |
Country Status (9)
| Country | Link |
|---|---|
| US (11) | US20160206586A1 (enExample) |
| EP (4) | EP3038605A1 (enExample) |
| JP (2) | JP2016528302A (enExample) |
| KR (4) | KR20160046813A (enExample) |
| CN (4) | CN109223725A (enExample) |
| AU (6) | AU2014314231A1 (enExample) |
| CA (2) | CA2918852A1 (enExample) |
| EA (2) | EA201690107A1 (enExample) |
| WO (2) | WO2015028472A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011001341A (es) | 2008-08-19 | 2011-03-29 | Xenoport Inc | Prodrogas de metil hidrogeno fumarato, sus composiciones farmaceuticas, y metodos de uso. |
| EP2887934A1 (en) | 2012-08-22 | 2015-07-01 | XenoPort, Inc. | Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects |
| US9597292B2 (en) | 2012-08-22 | 2017-03-21 | Xenoport, Inc. | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof |
| US10179118B2 (en) | 2013-03-24 | 2019-01-15 | Arbor Pharmaceuticals, Llc | Pharmaceutical compositions of dimethyl fumarate |
| WO2014197860A1 (en) | 2013-06-07 | 2014-12-11 | Xenoport, Inc. | Method of making monomethyl fumarate |
| US9421182B2 (en) | 2013-06-21 | 2016-08-23 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| JP2016534133A (ja) | 2013-09-06 | 2016-11-04 | ゼノポート，インコーポレイティド | （ｎ，ｎ−ジエチルカルバモイル）メチル メチル（２ｅ）ブト−２−エン−１，４−ジオエートの結晶形態、その合成方法及び使用 |
| IN2013MU03070A (enExample) * | 2013-09-25 | 2015-07-17 | Glenmark Pharmaceuticals Ltd | |
| CA2939990C (en) | 2014-02-28 | 2018-07-10 | Banner Life Sciences Llc | Controlled release enteric soft capsules of fumarate esters |
| US9636318B2 (en) | 2015-08-31 | 2017-05-02 | Banner Life Sciences Llc | Fumarate ester dosage forms |
| US10098863B2 (en) | 2014-02-28 | 2018-10-16 | Banner Life Sciences Llc | Fumarate esters |
| US9326947B1 (en) | 2014-02-28 | 2016-05-03 | Banner Life Sciences Llc | Controlled release fumarate esters |
| US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
| MA40982A (fr) * | 2014-11-19 | 2017-09-26 | Biogen Ma Inc | Formulation de bille pharmaceutique comprenant du fumarate de diméthyle |
| WO2016194004A1 (en) * | 2015-06-01 | 2016-12-08 | Sun Pharmaceutical Industries Ltd. | Pharmaceutical compositions of dimethyl fumarate |
| WO2017040272A1 (en) * | 2015-08-31 | 2017-03-09 | Banner Life Sciences Llc | Fumarate ester dosage forms |
| EA201800403A1 (ru) * | 2015-12-31 | 2018-12-28 | Заклады Фармацеутицне Польфарма С.А. | Способ получения покрытого кишечнорастворимой оболочкой гранулята, содержащего диметилфумарат |
| KR101800956B1 (ko) * | 2016-04-04 | 2018-01-25 | 주식회사 와이제이테크 | 파이토스핑고신과 효모추출물을 유효성분으로 포함하는 탈모방지 및 발모촉진용 조성물 |
| RU2616605C1 (ru) * | 2016-04-07 | 2017-04-18 | Олег Ростиславович Михайлов | Кристаллическая бета - модификация (Е)-диметилбутендиоата, способ её получения и фармацевтическая композиция на её основе |
| GR1009149B (el) * | 2016-10-25 | 2017-10-31 | Φαρματεν Αβεε | Φαρμακευτικα σκευασματα που περιλαμβανουν εναν εστερα φουμαρικου οξεως και μεθοδος παραγωγης αυτων |
| WO2020106330A1 (en) * | 2018-07-18 | 2020-05-28 | Pillsy, Inc. | Smart drug delivery and monitoring device, kit, and method of use for pill compounds |
| WO2020053218A1 (en) * | 2018-09-13 | 2020-03-19 | Almirall, S.A. | Treatment of psoriasis |
| TR201818859A2 (tr) * | 2018-12-07 | 2020-06-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Di̇meti̇l fumarat ve en az bi̇r kas gevşeti̇ci̇ ajan i̇çeren bi̇r kombi̇nasyon |
| PH12021552668A1 (en) * | 2019-05-31 | 2022-09-19 | Curacle Co Ltd | Enteric tablet containing dimethyl fumarate |
| WO2021142062A1 (en) | 2020-01-10 | 2021-07-15 | Banner Life Sciences Llc | Fumarate ester dosage forms with enhanced gastrointestinal tolerability |
| AR122023A1 (es) * | 2020-05-06 | 2022-08-03 | Imcyse Sa | Péptidos y métodos para el tratamiento de esclerosis múltiple |
| US20240216330A1 (en) * | 2021-04-02 | 2024-07-04 | Biogen Ma Inc. | Combination treatment methods of multiple sclerosis |
| CN115707456A (zh) * | 2021-08-19 | 2023-02-21 | 成都百裕制药股份有限公司 | 一种富马酸二甲酯肠溶微片及其制备方法 |
| US20230083647A1 (en) * | 2021-09-10 | 2023-03-16 | Battelle Energy Alliance, Llc | Reusable structures containing isotopes for simulating radioactive contamination environments, and methods of formation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814358C2 (de) | 1998-03-31 | 2002-01-17 | Fumapharm Ag Muri | Verwendung von Alkylhydrogenfumaraten zur Behandlung von Psoriasis, psoriatischer Arthritis, Neurodermitis und Enteritis regionalis Crohn |
| DE19848260C2 (de) | 1998-10-20 | 2002-01-17 | Fumapharm Ag Muri | Fumarsäure-Mikrotabletten |
| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| SI1799196T1 (sl) * | 2004-10-08 | 2016-10-28 | Forward Pharma A/S | Farmacevtski sestavki z nadzorovanim sproščanjem, obsegajoči ester fumarne kisline |
| WO2007042034A1 (en) * | 2005-10-07 | 2007-04-19 | Aditech Pharma Ab | Controlled release pharmaceutical compositions comprising a fumaric acid ester |
| CN101304732A (zh) * | 2005-10-07 | 2008-11-12 | Adi技术制药股份公司 | 包含富马酸酯的控释药物组合物 |
| EP2564839B1 (en) | 2009-01-09 | 2016-05-11 | Forward Pharma A/S | Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix |
| EP2379062A1 (en) * | 2009-01-09 | 2011-10-26 | Forward Pharma A/S | Pharmaceutical composition comprising one or more fumaric acid esters |
-
2014
- 2014-08-26 AU AU2014314231A patent/AU2014314231A1/en not_active Abandoned
- 2014-08-26 CN CN201811067557.1A patent/CN109223725A/zh active Pending
- 2014-08-26 CN CN201811202821.8A patent/CN109453133A/zh active Pending
- 2014-08-26 EA EA201690107A patent/EA201690107A1/ru unknown
- 2014-08-26 CN CN201480047436.4A patent/CN105658207A/zh active Pending
- 2014-08-26 AU AU2014314230A patent/AU2014314230A1/en not_active Abandoned
- 2014-08-26 EP EP14755672.4A patent/EP3038605A1/en not_active Withdrawn
- 2014-08-26 CA CA2918852A patent/CA2918852A1/en not_active Abandoned
- 2014-08-26 KR KR1020167004936A patent/KR20160046813A/ko not_active Ceased
- 2014-08-26 US US14/914,025 patent/US20160206586A1/en not_active Abandoned
- 2014-08-26 WO PCT/EP2014/068094 patent/WO2015028472A1/en not_active Ceased
- 2014-08-26 EA EA201690102A patent/EA201690102A1/ru unknown
- 2014-08-26 CN CN201480047438.3A patent/CN105682648A/zh active Pending
- 2014-08-26 JP JP2016537269A patent/JP2016528302A/ja active Pending
- 2014-08-26 CA CA2918846A patent/CA2918846A1/en not_active Abandoned
- 2014-08-26 US US14/914,031 patent/US20160206587A1/en not_active Abandoned
- 2014-08-26 JP JP2016537270A patent/JP2016531912A/ja active Pending
- 2014-08-26 KR KR1020217037254A patent/KR20210139485A/ko not_active Ceased
- 2014-08-26 EP EP14755818.3A patent/EP3038606A1/en not_active Withdrawn
- 2014-08-26 EP EP18198841.1A patent/EP3492072A1/en not_active Withdrawn
- 2014-08-26 KR KR1020167004935A patent/KR20160045728A/ko not_active Ceased
- 2014-08-26 KR KR1020217038001A patent/KR20210147082A/ko not_active Ceased
- 2014-08-26 EP EP18198844.5A patent/EP3517102A1/en not_active Withdrawn
- 2014-08-26 WO PCT/EP2014/068095 patent/WO2015028473A1/en not_active Ceased
-
2017
- 2017-05-02 US US15/584,439 patent/US20170231943A1/en not_active Abandoned
- 2017-10-03 US US15/723,749 patent/US20180021289A1/en not_active Abandoned
- 2017-12-07 US US15/834,799 patent/US20180092875A1/en not_active Abandoned
-
2018
- 2018-05-15 US US15/979,894 patent/US20180256530A1/en not_active Abandoned
- 2018-07-26 US US16/046,028 patent/US20180338946A1/en not_active Abandoned
- 2018-12-20 US US16/227,089 patent/US20190125711A1/en not_active Abandoned
-
2019
- 2019-03-06 US US16/294,515 patent/US20190201369A1/en not_active Abandoned
- 2019-11-18 AU AU2019268049A patent/AU2019268049B2/en not_active Ceased
- 2019-11-18 AU AU2019268052A patent/AU2019268052B2/en not_active Ceased
-
2020
- 2020-10-26 US US17/080,570 patent/US20210290582A1/en not_active Abandoned
-
2021
- 2021-08-13 AU AU2021215272A patent/AU2021215272A1/en not_active Abandoned
- 2021-11-19 AU AU2021269434A patent/AU2021269434A1/en not_active Abandoned
-
2022
- 2022-02-16 US US17/673,708 patent/US20220168255A1/en not_active Abandoned
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