EA201590546A1 - Способы лечения заболеваний, связанных с волосами - Google Patents

Способы лечения заболеваний, связанных с волосами

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Publication number
EA201590546A1
EA201590546A1 EA201590546A EA201590546A EA201590546A1 EA 201590546 A1 EA201590546 A1 EA 201590546A1 EA 201590546 A EA201590546 A EA 201590546A EA 201590546 A EA201590546 A EA 201590546A EA 201590546 A1 EA201590546 A1 EA 201590546A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
pharmaceutically acceptable
patient
necessary
hair
Prior art date
Application number
EA201590546A
Other languages
English (en)
Other versions
EA035986B1 (ru
Inventor
Джаммария Джулиани
Ральф Паус
Ювал Рамот
Серджо Барони
Франческа Вити
Сальваторе Беллинвия
Барбара Мардзани
Original Assignee
Ногра Фарма Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ногра Фарма Лимитед filed Critical Ногра Фарма Лимитед
Publication of EA201590546A1 publication Critical patent/EA201590546A1/ru
Publication of EA035986B1 publication Critical patent/EA035986B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Abstract

Предоставлены способы усиления эпидермальной регенерации у пациента при необходимости в таковом, включающие местное введение указанному пациенту фармацевтически приемлемой композиции, включающей N-ацетил-3-(4-аминофенил)-2-метоксипропионовую кислоту или ее фармацевтически приемлемую соль или стереоизомер и фармацевтически приемлемый эксципиент. Например, предоставлены способы лечения или улучшения рубцующейся алопеции, включающие местное введение пациенту при необходимости в таковом фармацевтически приемлемой композиции, включающей раскрытые соединения. Также предоставлены способы защиты клеток-предшественников волосяных фолликулов и композиции, включающие такое же применение раскрытых соединений.
EA201590546A 2012-09-13 2013-09-13 Способы лечения или облегчения плоского фолликулярного лишая EA035986B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261700623P 2012-09-13 2012-09-13
PCT/EP2013/069062 WO2014041140A1 (en) 2012-09-13 2013-09-13 Methods of treating hair related conditions

Publications (2)

Publication Number Publication Date
EA201590546A1 true EA201590546A1 (ru) 2015-08-31
EA035986B1 EA035986B1 (ru) 2020-09-09

Family

ID=49170707

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590546A EA035986B1 (ru) 2012-09-13 2013-09-13 Способы лечения или облегчения плоского фолликулярного лишая

Country Status (25)

Country Link
US (2) US20150250749A1 (ru)
EP (1) EP2895160B1 (ru)
JP (1) JP2015528479A (ru)
KR (1) KR20150054934A (ru)
CN (1) CN104837486A (ru)
AU (1) AU2013314288B2 (ru)
BR (1) BR112015005467A2 (ru)
CA (1) CA2883823A1 (ru)
CY (1) CY1120793T1 (ru)
DK (1) DK2895160T3 (ru)
EA (1) EA035986B1 (ru)
ES (1) ES2675169T3 (ru)
HR (1) HRP20181000T1 (ru)
HU (1) HUE037903T2 (ru)
IL (1) IL237449A0 (ru)
IN (1) IN2015DN02104A (ru)
LT (1) LT2895160T (ru)
MX (1) MX356888B (ru)
NZ (1) NZ705389A (ru)
PL (1) PL2895160T3 (ru)
PT (1) PT2895160T (ru)
SI (1) SI2895160T1 (ru)
TR (1) TR201809219T4 (ru)
UA (1) UA116215C2 (ru)
WO (1) WO2014041140A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
ES2806691T3 (es) 2009-02-16 2021-02-18 Nogra Pharma Ltd Compuestos de alquilamido y usos de los mismos
WO2013117744A2 (en) 2012-02-09 2013-08-15 Nogra Pharma Limited Methods of treating fibrosis
EP2844242A1 (en) 2012-04-18 2015-03-11 Nogra Pharma Limited Methods of treating lactose intolerance
BR112021015609A2 (pt) * 2019-02-08 2021-10-05 Nogra Pharma Limited Processo de fabricação de ácido 3-(4?-aminofenil)-2-metoxipropiônico, e análogos e intermediários do mesmo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2806691T3 (es) * 2009-02-16 2021-02-18 Nogra Pharma Ltd Compuestos de alquilamido y usos de los mismos
EP2844242A1 (en) * 2012-04-18 2015-03-11 Nogra Pharma Limited Methods of treating lactose intolerance

Also Published As

Publication number Publication date
IL237449A0 (en) 2015-04-30
KR20150054934A (ko) 2015-05-20
PL2895160T3 (pl) 2018-09-28
SI2895160T1 (sl) 2018-09-28
AU2013314288B2 (en) 2018-07-05
NZ705389A (en) 2018-08-31
CA2883823A1 (en) 2014-03-20
MX2015003278A (es) 2015-07-06
AU2013314288A1 (en) 2015-03-19
TR201809219T4 (tr) 2018-07-23
US20150250749A1 (en) 2015-09-10
EP2895160B1 (en) 2018-05-30
CN104837486A (zh) 2015-08-12
UA116215C2 (uk) 2018-02-26
ES2675169T3 (es) 2018-07-09
EP2895160A1 (en) 2015-07-22
DK2895160T3 (en) 2018-06-25
JP2015528479A (ja) 2015-09-28
WO2014041140A1 (en) 2014-03-20
EA035986B1 (ru) 2020-09-09
IN2015DN02104A (ru) 2015-08-14
US20210113505A1 (en) 2021-04-22
LT2895160T (lt) 2018-07-10
CY1120793T1 (el) 2020-05-29
PT2895160T (pt) 2018-06-29
HRP20181000T1 (hr) 2018-09-21
MX356888B (es) 2018-06-18
BR112015005467A2 (pt) 2017-07-04
HUE037903T2 (hu) 2018-09-28

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM RU