EA201300280A1 - BIODRAINABLE POLYMERIC THREAD AND METHOD FOR OBTAINING IT - Google Patents
BIODRAINABLE POLYMERIC THREAD AND METHOD FOR OBTAINING ITInfo
- Publication number
- EA201300280A1 EA201300280A1 EA201300280A EA201300280A EA201300280A1 EA 201300280 A1 EA201300280 A1 EA 201300280A1 EA 201300280 A EA201300280 A EA 201300280A EA 201300280 A EA201300280 A EA 201300280A EA 201300280 A1 EA201300280 A1 EA 201300280A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- lactic acid
- thread
- glycolide
- chitosan
- copolymer
- Prior art date
Links
Landscapes
- Materials For Medical Uses (AREA)
Abstract
Изобретение относится к области биотехнологии и медицины, а именно к технологии получения биоразлагаемых полимерных нитей, которые могут использоваться в производстве плетеных сосудистых стентов. Техническим результатом изобретения является применение биоразлагаемого полимерного материала в качестве основы монофиламентной нити с покрытием на базе хитозана для плетения сосудистых стентов при сохранении прочностных и упругих качеств, улучшение биосовместимости и прогнозирования скорости резорбции. Основу нити выполняют из гомополимера молочной кислоты или сополимера изомеров молочной кислоты с гликолидом путем формирования полимерной ленты толщиной 0,3-0,5 мм и шириной 2-4 мм многослойным напылением раствора гомополимера молочной кислоты или сополимера изомеров молочной кислоты с гликолидом в летучем растворителе на не адгезивную к материалу основы подложку. Ленту отделяют от подложки и растягивают в длину на 75-100% с одновременным закручиванием ее вокруг своей продольной оси. Основу покрывают хитозаном, сшитым генипином. Получают нить диаметром 0,15-0,55 мм со следующим составом, мас.%: основа - 80-99; покрытие - 1-20.The invention relates to the field of biotechnology and medicine, in particular to a technology for producing biodegradable polymer filaments, which can be used in the production of braided vascular stents. The technical result of the invention is the use of biodegradable polymeric material as the basis of monofilament yarn with a coating based on chitosan for weaving vascular stents while maintaining the strength and elastic properties, improving biocompatibility and prediction of resorption rate. The basis of the thread is made from a homopolymer of lactic acid or a copolymer of lactic acid isomers with glycolide by forming a polymer tape 0.3-0.5 mm thick and 2-4 mm wide by multilayer spraying of a solution of lactic acid homopolymer or a copolymer of lactic acid isomers with a glycolide in a volatile solvent on non-adhesive backing material. The tape is separated from the substrate and stretch in length by 75-100% with its simultaneous twisting around its longitudinal axis. The base is coated with chitosan, crosslinked with genipin. Get the thread with a diameter of 0.15-0.55 mm with the following composition, wt.%: Base - 80-99; coverage - 1-20.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201300280A EA022047B1 (en) | 2013-03-26 | 2013-03-26 | Biodegradable polymer thread and method for producing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201300280A EA022047B1 (en) | 2013-03-26 | 2013-03-26 | Biodegradable polymer thread and method for producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201300280A1 true EA201300280A1 (en) | 2014-09-30 |
EA022047B1 EA022047B1 (en) | 2015-10-30 |
Family
ID=51628519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201300280A EA022047B1 (en) | 2013-03-26 | 2013-03-26 | Biodegradable polymer thread and method for producing the same |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA022047B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112516391A (en) * | 2020-12-21 | 2021-03-19 | 辽宁垠艺生物科技股份有限公司 | Drug loading method for stent with membrane |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6162537A (en) * | 1996-11-12 | 2000-12-19 | Solutia Inc. | Implantable fibers and medical articles |
RU2408746C1 (en) * | 2009-06-29 | 2011-01-10 | Государственное образовательное учреждение высшего профессионального образования "Московский государственный текстильный университет имени А.Н. Косыгина" | Method of producing chitosan-containing threads |
RU115663U1 (en) * | 2011-11-01 | 2012-05-10 | Российская Федерация, от имени которой выступает Министерство промышленности и торговли Российской Федерации (Минпромторг России) | BIODEGRADABLE SEAMED SURGICAL COATED SURGERY |
-
2013
- 2013-03-26 EA EA201300280A patent/EA022047B1/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112516391A (en) * | 2020-12-21 | 2021-03-19 | 辽宁垠艺生物科技股份有限公司 | Drug loading method for stent with membrane |
Also Published As
Publication number | Publication date |
---|---|
EA022047B1 (en) | 2015-10-30 |
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Legal Events
Date | Code | Title | Description |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KG TJ TM |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY KZ RU |