EA201101715A1 - METHOD OF OBTAINING A BIOLOGICALLY ACTIVE COATING - Google Patents

METHOD OF OBTAINING A BIOLOGICALLY ACTIVE COATING

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Publication number
EA201101715A1
EA201101715A1 EA201101715A EA201101715A EA201101715A1 EA 201101715 A1 EA201101715 A1 EA 201101715A1 EA 201101715 A EA201101715 A EA 201101715A EA 201101715 A EA201101715 A EA 201101715A EA 201101715 A1 EA201101715 A1 EA 201101715A1
Authority
EA
Eurasian Patent Office
Prior art keywords
biologically active
implants
hydroxyapatite
coating
mixture
Prior art date
Application number
EA201101715A
Other languages
Russian (ru)
Other versions
EA019608B1 (en
Inventor
Сергей Иванович Твердохлебов
Евгений Николаевич Больбасов
Евгений Викторович Шестериков
Original Assignee
Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Национальный Исследовательский Томский Политехнический Университет" (Фгбоу Впо Ни Тпу)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Национальный Исследовательский Томский Политехнический Университет" (Фгбоу Впо Ни Тпу) filed Critical Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Национальный Исследовательский Томский Политехнический Университет" (Фгбоу Впо Ни Тпу)
Priority to EA201101715A priority Critical patent/EA019608B1/en
Publication of EA201101715A1 publication Critical patent/EA201101715A1/en
Publication of EA019608B1 publication Critical patent/EA019608B1/en

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Abstract

Изобретение относится к области медицины, а именно к травматологии и ортопедии, и может быть использовано для получения пористых биологически активных покрытий на металлических и керамических имплантатах. Изобретение направлено на получение биологически активного гидрофильного покрытия на металлических и керамических имплантатах. Указанный технический результат достигают тем, что в способе получения биологически активного покрытия на имплантатах из металлических и керамических материалов используют порошок поливинилиденфторида, растворенный в смеси ацетона и бутилацетата, используют смесь порошков гидроксиапатита и трикальцийфосфата, обработанных в шаровой мельнице в присутствии бутилацетата. Раствор поливинилиденфторида в смесевом растворителе и дисперсию смеси порошков гидроксиапатита и трикальцийфосфата гомогенизируют в шаровой мельнице и наносят пневматическим напылением на шероховатые и прогретые до температуры не более 90°С имплантаты. Покрытие формируют в камерной печи при температуре не менее 180°С. Затем покрытие модифицируют, нанося слой фосфатов кальция в атмосфере аргона в течение не более 1 ч, путем высокочастотного магнетронного распыления мишени, изготовленной из гидроксиапатита.The invention relates to the field of medicine, namely to traumatology and orthopedics, and can be used to obtain porous biologically active coatings on metal and ceramic implants. The invention is directed to the production of biologically active hydrophilic coatings on metal and ceramic implants. This technical result is achieved by the use of polyvinylidene fluoride powder dissolved in a mixture of acetone and butyl acetate in a method for producing a biologically active coating on implants made of metal and ceramic materials, a mixture of hydroxyapatite and tricalcium phosphate powders processed in a ball mill in the presence of butyl acetate is used. A solution of polyvinylidene fluoride in a mixed solvent and a dispersion of a mixture of hydroxyapatite and tricalcium phosphate powders are homogenized in a ball mill and applied by pneumatic spraying on rough implants heated to a temperature not exceeding 90 ° C. The coating is formed in a chamber furnace at a temperature of at least 180 ° C. Then the coating is modified by applying a layer of calcium phosphate in an argon atmosphere for no more than 1 hour by means of high-frequency magnetron sputtering of a target made of hydroxyapatite.

EA201101715A 2011-12-14 2011-12-14 Method for producing biologically active coating EA019608B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EA201101715A EA019608B1 (en) 2011-12-14 2011-12-14 Method for producing biologically active coating

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EA201101715A EA019608B1 (en) 2011-12-14 2011-12-14 Method for producing biologically active coating

Publications (2)

Publication Number Publication Date
EA201101715A1 true EA201101715A1 (en) 2013-06-28
EA019608B1 EA019608B1 (en) 2014-04-30

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Application Number Title Priority Date Filing Date
EA201101715A EA019608B1 (en) 2011-12-14 2011-12-14 Method for producing biologically active coating

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EA (1) EA019608B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4428209A1 (en) * 2023-03-10 2024-09-11 SK On Co., Ltd. Adhesive composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2206642C2 (en) * 2000-01-31 2003-06-20 Мамаев Анатолий Иванович Method for modifying medical products (alternatives)
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
SE522749C2 (en) * 2002-03-04 2004-03-02 Cerbio Tech Ab Surface coating process, surface coating device and biocompatible coating
RU2287315C2 (en) * 2005-01-11 2006-11-20 Общество с ограниченной ответственностью Концерн научно-производственное объединение "Биотехника" Method for obtaining hydroxyapatite coverings

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Publication number Publication date
EA019608B1 (en) 2014-04-30

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU