EA201070361A1 - Полиморфные разновидности (s)-2-((4-бензофуранил)карбониламинометил)-1-((4-(2-метил-5-(4-фторфенил))тиазолил)карбонил)пиперидина - Google Patents

Полиморфные разновидности (s)-2-((4-бензофуранил)карбониламинометил)-1-((4-(2-метил-5-(4-фторфенил))тиазолил)карбонил)пиперидина

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Publication number
EA201070361A1
EA201070361A1 EA201070361A EA201070361A EA201070361A1 EA 201070361 A1 EA201070361 A1 EA 201070361A1 EA 201070361 A EA201070361 A EA 201070361A EA 201070361 A EA201070361 A EA 201070361A EA 201070361 A1 EA201070361 A1 EA 201070361A1
Authority
EA
Eurasian Patent Office
Prior art keywords
carbonylaminomethyl
fluorophenyl
methyl
benzofuranilyl
benzofuranyl
Prior art date
Application number
EA201070361A
Other languages
English (en)
Inventor
Линда Джейн Киндон
Original Assignee
Глэксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глэксо Груп Лимитед filed Critical Глэксо Груп Лимитед
Publication of EA201070361A1 publication Critical patent/EA201070361A1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Новые кристаллические формы (S)-2-((4-бензофуранил)карбониламинометил)-1-((4-(2-метил-5-(4-фторфенил))тиазолил)карбонил)пиперидина, способы их получения и применения в медицине в качестве антагониста орексинового рецептора.
EA201070361A 2007-09-13 2008-09-11 Полиморфные разновидности (s)-2-((4-бензофуранил)карбониламинометил)-1-((4-(2-метил-5-(4-фторфенил))тиазолил)карбонил)пиперидина EA201070361A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0717882.5A GB0717882D0 (en) 2007-09-13 2007-09-13 Novel pharmaceutical
PCT/EP2008/062064 WO2009034133A1 (en) 2007-09-13 2008-09-11 Polymorph forms of (s)-2-((4-benzofuranyl)carbonylaminomethyl)-1-((4-(2-methyl-5-(4-fluorophenyl)thiazolyl)carbonyl)piperidine

Publications (1)

Publication Number Publication Date
EA201070361A1 true EA201070361A1 (ru) 2010-08-30

Family

ID=38658914

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070361A EA201070361A1 (ru) 2007-09-13 2008-09-11 Полиморфные разновидности (s)-2-((4-бензофуранил)карбониламинометил)-1-((4-(2-метил-5-(4-фторфенил))тиазолил)карбонил)пиперидина

Country Status (22)

Country Link
US (1) US20100286201A1 (ru)
EP (1) EP2190842A1 (ru)
JP (1) JP2010539133A (ru)
KR (1) KR20100057035A (ru)
CN (1) CN101801968A (ru)
AR (1) AR068414A1 (ru)
AU (1) AU2008297126A1 (ru)
BR (1) BRPI0816757A2 (ru)
CA (1) CA2699472A1 (ru)
CL (1) CL2008002688A1 (ru)
CO (1) CO6260068A2 (ru)
CR (1) CR11306A (ru)
DO (1) DOP2010000066A (ru)
EA (1) EA201070361A1 (ru)
GB (1) GB0717882D0 (ru)
MA (1) MA31692B1 (ru)
MX (1) MX2010002895A (ru)
PE (1) PE20090639A1 (ru)
TW (1) TW200927748A (ru)
UY (1) UY31337A1 (ru)
WO (1) WO2009034133A1 (ru)
ZA (1) ZA201001083B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120101110A1 (en) * 2010-10-26 2012-04-26 Sangamesh Badiger Diaza-spiro[5.5]undecanes
WO2017194548A1 (en) 2016-05-10 2017-11-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE293101T1 (de) * 2000-06-16 2005-04-15 Smithkline Beecham Plc Piperidine zur verwendung als orexin rezeptor antagonisten
US20060178307A1 (en) * 2005-01-26 2006-08-10 The Regents Of The University Of California Modulation of NMDA receptor currents via orexin receptor and/or CRF receptor

Also Published As

Publication number Publication date
AR068414A1 (es) 2009-11-18
CO6260068A2 (es) 2011-03-22
CA2699472A1 (en) 2009-03-19
PE20090639A1 (es) 2009-06-25
CL2008002688A1 (es) 2009-11-27
MA31692B1 (fr) 2010-09-01
EP2190842A1 (en) 2010-06-02
MX2010002895A (es) 2010-04-01
ZA201001083B (en) 2010-10-27
TW200927748A (en) 2009-07-01
CN101801968A (zh) 2010-08-11
DOP2010000066A (es) 2010-04-15
US20100286201A1 (en) 2010-11-11
GB0717882D0 (en) 2007-10-24
AU2008297126A1 (en) 2009-03-19
BRPI0816757A2 (pt) 2015-03-17
CR11306A (es) 2010-04-20
WO2009034133A1 (en) 2009-03-19
UY31337A1 (es) 2009-04-30
JP2010539133A (ja) 2010-12-16
KR20100057035A (ko) 2010-05-28

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