EA201001558A1 - COMPOSITIONS CONTAINING anr NOX INHIBITORS TO SUPPRESS ACTIVE FORMS OF OXYGEN - Google Patents

COMPOSITIONS CONTAINING anr NOX INHIBITORS TO SUPPRESS ACTIVE FORMS OF OXYGEN

Info

Publication number
EA201001558A1
EA201001558A1 EA201001558A EA201001558A EA201001558A1 EA 201001558 A1 EA201001558 A1 EA 201001558A1 EA 201001558 A EA201001558 A EA 201001558A EA 201001558 A EA201001558 A EA 201001558A EA 201001558 A1 EA201001558 A1 EA 201001558A1
Authority
EA
Eurasian Patent Office
Prior art keywords
arnox
natural
tazetta
anr
oxygen
Prior art date
Application number
EA201001558A
Other languages
Russian (ru)
Inventor
Дейл Керн
Кристиан Мэдоуз
Original Assignee
Ню Скин Интернэшнл, Инк.
Нокс Текнолоджиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ню Скин Интернэшнл, Инк., Нокс Текнолоджиз, Инк. filed Critical Ню Скин Интернэшнл, Инк.
Publication of EA201001558A1 publication Critical patent/EA201001558A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Abstract

Изобретение относится к средствам для блокирования сывороточных факторов старения и методам их применения. Конкретнее, изобретение относится к веществам, которые называются здесь "нарактин" для обозначения любого одного из нескольких природных ингибиторов arNOX, присутствующих в порошке N.Tazetta (нарцисс) или способных усилить порошок N. tazetta до уровня ингибирования, соизмеримого со свежими экстрактами N. tazetta, и способам применения "нарактинов" для предотвращения или лечения расстройств и осложнений расстройств, возникающих в результате повреждения клеток, вызванного связанной со старением изоформой NADH оксидазы (arNOX). В одном варианте осуществления вещества изобретения включают по меньшей мере один природный нарактин. К тому же такие природные нарактины способны увеличить анти-arNOX эффект других природных веществ, ингибирующих arNOX.The invention relates to means for blocking serum aging factors and methods for their use. More specifically, the invention relates to substances that are referred to herein as “naractin” to mean any one of several natural arNOX inhibitors present in N. Tazetta powder (narcissus) or capable of enhancing N. tazetta powder to a level of inhibition comparable with fresh N. tazetta extracts , and methods of using “naractins” to prevent or treat disorders and complications of disorders resulting from cell damage caused by aging of the NADH oxidase isoform (arNOX). In one embodiment, the compounds of the invention include at least one natural nractin. In addition, such natural nractins can increase the anti-arNOX effect of other natural substances that inhibit arNOX.

EA201001558A 2008-03-28 2008-03-28 COMPOSITIONS CONTAINING anr NOX INHIBITORS TO SUPPRESS ACTIVE FORMS OF OXYGEN EA201001558A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/058683 WO2009120214A1 (en) 2008-03-28 2008-03-28 Compositions comprising anrnox-inhibitors for the inhibition of reactive oxygen species

Publications (1)

Publication Number Publication Date
EA201001558A1 true EA201001558A1 (en) 2011-06-30

Family

ID=40056186

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001558A EA201001558A1 (en) 2008-03-28 2008-03-28 COMPOSITIONS CONTAINING anr NOX INHIBITORS TO SUPPRESS ACTIVE FORMS OF OXYGEN

Country Status (11)

Country Link
EP (1) EP2280714A1 (en)
JP (1) JP2011515466A (en)
KR (1) KR20110000745A (en)
CN (1) CN102014930A (en)
AU (1) AU2008353441A1 (en)
CA (1) CA2719833A1 (en)
EA (1) EA201001558A1 (en)
IL (1) IL208324A0 (en)
MX (1) MX2010010668A (en)
WO (1) WO2009120214A1 (en)
ZA (1) ZA201007247B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2699726C2 (en) * 2013-01-03 2019-09-09 Юниверсите Де Бордо SELECTIVE INHIBITORY PEPTIDES Nox-1 AND USE THEREOF

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2645993B1 (en) * 2010-12-03 2016-11-02 Allergan, Inc. Pharmaceutical cream compositions comprising oxymetazoline
EP2659004B1 (en) * 2010-12-30 2017-08-30 Avon Products, Inc. Modulation of dynein in skin
CN102440927B (en) * 2011-02-10 2012-11-21 漳州市格莱雅化妆品有限公司 Daffodil whitening toning lotion cosmetic
CN102641223A (en) * 2011-02-18 2012-08-22 株式会社爱茉莉太平洋 Cosmetic composition for improving skin tone or skin elasticity
CN102526160B (en) * 2012-01-31 2015-08-12 王玉石 Outward for the composition and use thereof of human body skin
US9125843B2 (en) 2013-10-03 2015-09-08 Elc Management Llc Methods and compositions for improving the appearance of skin
JP6698358B2 (en) * 2015-03-12 2020-05-27 Ｓｈｉｏｄａライフサイエンス株式会社 A sweat secretagogue and a preventive or therapeutic agent for dry skin containing the sweat secretagogue
KR102309958B1 (en) * 2015-03-24 2021-10-07 주식회사 엘지생활건강 A cosmetic composition for skin improvement comprising bulb extract
US9750682B2 (en) 2015-07-30 2017-09-05 Elc Management, Llc Methods and compositions for improving the appearance of skin
CN105581364B (en) * 2016-03-07 2017-07-07 云南瑞升烟草技术（集团）有限公司 A kind of preparation method and application of the astaxanthin microcapsules in cigarette shreds
JP6912771B2 (en) * 2017-04-11 2021-08-04 学校法人立命館 Preventive or ameliorating agent for seborrheic keratosis
US10251832B2 (en) 2017-05-26 2019-04-09 Mary Kay Inc. Cosmetic compositions and methods
CN107927779A (en) * 2017-11-27 2018-04-20 爱可道生物科技有限公司 A kind of beautifying face and moistering lotion oral liquid and preparation method thereof
US20230073286A1 (en) * 2019-11-06 2023-03-09 Korea Research Institute Of Bioscience And Biotechnology Cosmetic composition for preventing skin aging and reducing skin wrinkles, comprising viburnum stellato-tomentosum extract

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559328A (en) * 1984-06-21 1985-12-17 Warner-Lambert Company Non-steroidal anti-inflammatory compounds to treat inflammation
LU87408A1 (en) * 1988-12-16 1990-07-10 Oreal USE OF SALICYL DERIVATIVES FOR THE TREATMENT OF AGING SKIN
EP0614353A1 (en) * 1991-11-25 1994-09-14 Richardson-Vicks, Inc. Compositions for regulating skin wrinkles and/or skin atrophy
EP0614354B1 (en) * 1991-11-25 2001-01-17 Richardson-Vicks, Inc. Use of salicylic acid for regulating skin atrophy
JPH1180002A (en) * 1997-09-12 1999-03-23 Noevir Co Ltd Preparation for external use for skin preventing aging
FR2782269B1 (en) * 1998-08-17 2001-08-31 Oreal COSMETIC AND / OR DERMATOLOGICAL COMPOSITION CONTAINING SALICYLIC ACID OR A SALICYLIC ACID DERIVATIVE AND USE THEREOF
US20030199558A1 (en) * 2001-12-28 2003-10-23 Integriderm, Inc. Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners
US20050226947A1 (en) * 2004-02-04 2005-10-13 Dale Kern Agents for sequestering serum aging factors and uses therefore
US20060275229A1 (en) * 2005-05-17 2006-12-07 Sreekumar Pillai Skin care active complex and methods of using same
EP2010132A1 (en) * 2006-04-18 2009-01-07 DSMIP Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2699726C2 (en) * 2013-01-03 2019-09-09 Юниверсите Де Бордо SELECTIVE INHIBITORY PEPTIDES Nox-1 AND USE THEREOF

Also Published As

Publication number Publication date
IL208324A0 (en) 2010-12-30
MX2010010668A (en) 2011-04-26
CA2719833A1 (en) 2009-10-01
AU2008353441A1 (en) 2009-10-01
EP2280714A1 (en) 2011-02-09
KR20110000745A (en) 2011-01-05
JP2011515466A (en) 2011-05-19
WO2009120214A1 (en) 2009-10-01
AU2008353441A2 (en) 2010-11-25
CN102014930A (en) 2011-04-13
ZA201007247B (en) 2011-12-28

Similar Documents

Publication Publication Date Title
EA201001558A1 (en) COMPOSITIONS CONTAINING anr NOX INHIBITORS TO SUPPRESS ACTIVE FORMS OF OXYGEN
WO2007072179A3 (en) Histone deacetylase inhibitors for enhancing activity of antifungal agents
EA201491008A1 (en) COMBINATION OF ANTHAGONIST CRTH2 AND PROTONE PUMP INHIBITOR FOR THE TREATMENT OF EOSINOPHIL ESOPHAGITIS
EA200801291A1 (en) CARBONYLAMINOPYRROPYRAZOLES AS AN EFFICIENT KINAZ INHIBITORS
UY31209A1 (en) USE OF HOMO AND COPOLIMEROS FOR THE STABILIZATION OF FORMULATIONS OF ACTIVE PRINCIPLES
EA201100440A1 (en) COMPOUNDS, COMPOSITIONS AND METHODS OF THEIR APPLICATION FOR CORRECTION OF URIC ACID LEVEL
EA201100378A1 (en) HEDGEHOG SIGNAL MODULATORS
EA200900360A1 (en) NEW LOW-MOLECULAR INHIBITORS MDM2 AND THEIR USE
EA201270184A1 (en) TREATMENT OF LIVER DISORDERS PI3K INHIBITORS
EA201100119A1 (en) CHEMICAL COMPOUNDS 251
CO6640311A2 (en) Compounds, thioacetate compositions and methods of use
BR112012032193A2 (en) phenylthioacetate compound, compositions and methods of use
EA201171396A1 (en) TREATMENT OF PORTAL HYPERTENSION AND RESTORATION OF LIVER FUNCTION BY MEANS OF L-ORNITINPHENYL ACETATE
WO2007090068A3 (en) Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif)
ATE549336T1 (en) HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF AND THEIR USE AS PROTEIN KINASE INHIBITORS
WO2010031056A3 (en) Methods and compositions for modulating ire1, src, and abl activity
EA200870019A1 (en) LACTAMIC CONNECTIONS AND METHODS OF THEIR APPLICATION
UA98297C2 (en) Triazolopyridazines as tyrosine kinase modulators
MA32393B1 (en) Compounds and compounds that act as kinase inhibitors
EA200901212A1 (en) 3-IMIDAZOLYLINDOLES INTENDED FOR THE TREATMENT OF PROLIFERATIVE DISEASES
EA201500769A1 (en) E1 INHIBITORS ACTIVATING ENZYMES
GEP20156376B (en) Solid herbicide compositions with built-in adjuvant
WO2012058645A8 (en) Heterocyclic tyrosine kinase inhibitors
EA200900613A1 (en) SPIROKETONE ACETYL-COA-CARBOXYLAS INHIBITORS
WO2009012357A3 (en) Methods to identify and enrich for populations of ovarian cancer stem cells and somatic ovarian stem cells and uses thereof