EA201000617A1 - Комбинация, включающая производные пурина и другие соединения, и ее применение для лечения воспалительных и обструктивных заболеваний дыхательных путей - Google Patents
Комбинация, включающая производные пурина и другие соединения, и ее применение для лечения воспалительных и обструктивных заболеваний дыхательных путейInfo
- Publication number
- EA201000617A1 EA201000617A1 EA201000617A EA201000617A EA201000617A1 EA 201000617 A1 EA201000617 A1 EA 201000617A1 EA 201000617 A EA201000617 A EA 201000617A EA 201000617 A EA201000617 A EA 201000617A EA 201000617 A1 EA201000617 A1 EA 201000617A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- inflammatory
- antagonist
- treatment
- inhibitor
- purin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
В заявке описано лекарственное средство, включающее по отдельности или совместно компонент (А), который представляет собой агонист аденозинового рецептора А, определенный в описании; и компонент (В), который представляет собой одно или большее количество соединений, выбранных из группы, включающей: (i) кортикостероид, (ii) агонист бета-2 адренорецептора, (iii) антимускариновое средство, (iv) антагонист A, (v) антигистамин, (vi) ингибитор каспазы, (vii) ингибитор ENaC, (viii) антагонист LTB4, (ix) антагонист LTD4, (х) ингибитор серинпротеазы, (xi) ингибитор PDE4 и (xii) двойной агонист бета-2 адренорецептора/мускариновый антагонист, предназначенное для одновременного, последовательного или раздельного введения при лечении воспалительного или обструктивного заболевания дыхательных путей.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07118721 | 2007-10-17 | ||
PCT/EP2008/063869 WO2009050198A2 (en) | 2007-10-17 | 2008-10-15 | Combination comprising purine derivatives and other compounds and the use thereof for the treatment of inflammatory and obstructive airway diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201000617A1 true EA201000617A1 (ru) | 2010-10-29 |
Family
ID=39185790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201000617A EA201000617A1 (ru) | 2007-10-17 | 2008-10-15 | Комбинация, включающая производные пурина и другие соединения, и ее применение для лечения воспалительных и обструктивных заболеваний дыхательных путей |
Country Status (21)
Country | Link |
---|---|
US (1) | US20090181934A1 (ru) |
EP (1) | EP2211865A2 (ru) |
JP (1) | JP2011500630A (ru) |
KR (1) | KR20100075925A (ru) |
CN (1) | CN101827596A (ru) |
AR (1) | AR068879A1 (ru) |
AU (1) | AU2008313788A1 (ru) |
BR (1) | BRPI0818005A2 (ru) |
CA (1) | CA2702942A1 (ru) |
CL (1) | CL2008003057A1 (ru) |
CR (1) | CR11341A (ru) |
CU (1) | CU20100065A7 (ru) |
EA (1) | EA201000617A1 (ru) |
IL (1) | IL204723A0 (ru) |
MA (1) | MA31796B1 (ru) |
MX (1) | MX2010004252A (ru) |
PE (1) | PE20091392A1 (ru) |
TN (1) | TN2010000168A1 (ru) |
TW (1) | TW200927129A (ru) |
WO (1) | WO2009050198A2 (ru) |
ZA (1) | ZA201002336B (ru) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT200500281A (es) * | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0500785D0 (en) | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
GB0607944D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
GB0607950D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
PL2013211T3 (pl) | 2006-04-21 | 2012-08-31 | Novartis Ag | Pochodne puryny do zastosowania jako agoniści receptora adenozyny A2A |
GB0607953D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
GB0607948D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
GB0607945D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
EP1903044A1 (en) * | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
CN101553459A (zh) * | 2006-11-10 | 2009-10-07 | 诺瓦提斯公司 | 环戊烯二醇单乙酸酯衍生物 |
JP2011500631A (ja) * | 2007-10-17 | 2011-01-06 | ノバルティス アーゲー | アデノシンa1受容体リガンドとしてのプリン誘導体 |
CN104321057B (zh) | 2012-04-20 | 2016-09-14 | Ucb医药有限公司 | 用于治疗帕金森病的方法 |
CA3126735A1 (en) | 2019-01-11 | 2020-07-16 | Omeros Corporation | Methods and compositions for treating cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT200500281A (es) * | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0607950D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
PL2013211T3 (pl) * | 2006-04-21 | 2012-08-31 | Novartis Ag | Pochodne puryny do zastosowania jako agoniści receptora adenozyny A2A |
GB0607953D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
GB0607945D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
-
2008
- 2008-10-08 US US12/247,764 patent/US20090181934A1/en not_active Abandoned
- 2008-10-15 MX MX2010004252A patent/MX2010004252A/es not_active Application Discontinuation
- 2008-10-15 BR BRPI0818005 patent/BRPI0818005A2/pt not_active IP Right Cessation
- 2008-10-15 CA CA2702942A patent/CA2702942A1/en not_active Abandoned
- 2008-10-15 AR ARP080104494A patent/AR068879A1/es not_active Application Discontinuation
- 2008-10-15 EA EA201000617A patent/EA201000617A1/ru unknown
- 2008-10-15 KR KR1020107008300A patent/KR20100075925A/ko not_active Application Discontinuation
- 2008-10-15 AU AU2008313788A patent/AU2008313788A1/en not_active Abandoned
- 2008-10-15 EP EP08838649A patent/EP2211865A2/en not_active Withdrawn
- 2008-10-15 CN CN200880112188A patent/CN101827596A/zh active Pending
- 2008-10-15 JP JP2010529369A patent/JP2011500630A/ja active Pending
- 2008-10-15 WO PCT/EP2008/063869 patent/WO2009050198A2/en active Application Filing
- 2008-10-15 PE PE2008001774A patent/PE20091392A1/es not_active Application Discontinuation
- 2008-10-16 TW TW097139728A patent/TW200927129A/zh unknown
- 2008-10-16 CL CL2008003057A patent/CL2008003057A1/es unknown
-
2010
- 2010-03-25 IL IL204723A patent/IL204723A0/en unknown
- 2010-03-26 CR CR11341A patent/CR11341A/es not_active Application Discontinuation
- 2010-04-01 ZA ZA2010/02336A patent/ZA201002336B/en unknown
- 2010-04-14 CU CU20100065A patent/CU20100065A7/es unknown
- 2010-04-16 TN TN2010000168A patent/TN2010000168A1/fr unknown
- 2010-04-30 MA MA32802A patent/MA31796B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
TW200927129A (en) | 2009-07-01 |
ZA201002336B (en) | 2011-04-28 |
AR068879A1 (es) | 2009-12-09 |
KR20100075925A (ko) | 2010-07-05 |
CR11341A (es) | 2010-05-06 |
PE20091392A1 (es) | 2009-10-14 |
US20090181934A1 (en) | 2009-07-16 |
CN101827596A (zh) | 2010-09-08 |
WO2009050198A2 (en) | 2009-04-23 |
CA2702942A1 (en) | 2009-04-23 |
MA31796B1 (fr) | 2010-10-01 |
CU20100065A7 (es) | 2011-10-05 |
IL204723A0 (en) | 2010-11-30 |
JP2011500630A (ja) | 2011-01-06 |
CL2008003057A1 (es) | 2009-06-26 |
MX2010004252A (es) | 2010-04-30 |
WO2009050198A3 (en) | 2009-09-11 |
EP2211865A2 (en) | 2010-08-04 |
BRPI0818005A2 (pt) | 2015-04-14 |
AU2008313788A1 (en) | 2009-04-23 |
TN2010000168A1 (en) | 2011-11-11 |
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