EA200900022A1 - Способ приготовления полимерных матриц с фармацевтическими композициями - Google Patents

Способ приготовления полимерных матриц с фармацевтическими композициями

Info

Publication number
EA200900022A1
EA200900022A1 EA200900022A EA200900022A EA200900022A1 EA 200900022 A1 EA200900022 A1 EA 200900022A1 EA 200900022 A EA200900022 A EA 200900022A EA 200900022 A EA200900022 A EA 200900022A EA 200900022 A1 EA200900022 A1 EA 200900022A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compound
pharmaceutical compositions
preparing polymeric
polymeric matrixes
irradiation
Prior art date
Application number
EA200900022A
Other languages
English (en)
Inventor
Эйльвин Йорг Анджело Атанасайус Диас
Петер Бруин
Одри Пети
Original Assignee
ДСМ АйПи АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA200900022A1 publication Critical patent/EA200900022A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polymerisation Methods In General (AREA)

Abstract

Настоящее изобретение относится к способу приготовления матрицы, наполненной лекарственным средством, содержащей фармацевтическое соединение, путем полимеризации полимеризационной смеси, вызванной облучением, в присутствии по меньшей мере одного чувствительного фармацевтического соединения, где полимеризационная смесь содержит: a) по меньшей мере одно полимеризующееся соединение, b) при необходимости, по меньшей мере один фотосенсибилизатор, c) при необходимости, по меньшей мере одну добавку, которые выбираются таким образом, что чувствительное фармацевтическое соединение разрушается менее чем на 2%, или которые выбираются таким образом, что чувствительное фармацевтическое соединение защищено против разрушения таким образом, что разрушение составляет около 50% или менее по сравнению с облучением с компонентом, который образует радикал.
EA200900022A 2006-06-15 2007-06-12 Способ приготовления полимерных матриц с фармацевтическими композициями EA200900022A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06012347A EP1813268A1 (en) 2006-06-15 2006-06-15 Method for preparing polymeric matrices by radiation in the presence of sensitive pharmaceutical compounds
PCT/EP2007/005176 WO2007144143A1 (en) 2006-06-15 2007-06-12 Method for preparing polymeric matrices by radiation in the presence of sensitive pharmaceutical compounds

Publications (1)

Publication Number Publication Date
EA200900022A1 true EA200900022A1 (ru) 2009-04-28

Family

ID=37890310

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200900022A EA200900022A1 (ru) 2006-06-15 2007-06-12 Способ приготовления полимерных матриц с фармацевтическими композициями

Country Status (8)

Country Link
US (1) US20100068252A1 (ru)
EP (2) EP1813268A1 (ru)
JP (1) JP2009539906A (ru)
CN (1) CN101466358A (ru)
AU (1) AU2007260229A1 (ru)
BR (1) BRPI0711474A2 (ru)
EA (1) EA200900022A1 (ru)
WO (1) WO2007144143A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009044403A2 (en) * 2007-10-05 2009-04-09 Juvenis Ltd. Injectable biodegradable polymer compositions for soft tissue repair and augmentation
PL3223799T3 (pl) * 2014-11-30 2020-06-15 Patel Sposób otrzymywania kompozycji składnik farmaceutyczny-polimer
CN106540320A (zh) * 2016-12-13 2017-03-29 天津高卓科技有限公司 一种节能环保型植入医疗器械上药物涂层的涂覆方法
CN108467464A (zh) * 2018-04-02 2018-08-31 常熟理工学院 含壬二酸可见光固化水凝胶及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030087985A1 (en) * 1990-10-15 2003-05-08 Hubbell Jeffrey A. Gels for encapsulation of biological materials
US6916488B1 (en) * 1999-11-05 2005-07-12 Biocure, Inc. Amphiphilic polymeric vesicles
AU4304901A (en) * 1999-11-15 2001-06-04 Biocure, Inc. Responsive polymeric hollow particles
AU2004220629A1 (en) * 2003-03-12 2004-09-23 3M Innovative Properties Company Polymer compositions with bioactive silver, copper or zinc compounds, medical articles, and processes
US20060222677A1 (en) * 2004-01-14 2006-10-05 Bianca Baroli Method of protecting sensitive molecules from a photo-polymerizing environment

Also Published As

Publication number Publication date
WO2007144143A1 (en) 2007-12-21
CN101466358A (zh) 2009-06-24
WO2007144143A8 (en) 2009-01-15
EP1813268A1 (en) 2007-08-01
BRPI0711474A2 (pt) 2012-07-10
EP2029109A1 (en) 2009-03-04
US20100068252A1 (en) 2010-03-18
AU2007260229A1 (en) 2007-12-21
JP2009539906A (ja) 2009-11-19

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