EA200870430A1 - INTRAMUSCULAR ANTIVIRUS METHODS OF TREATMENT - Google Patents
INTRAMUSCULAR ANTIVIRUS METHODS OF TREATMENTInfo
- Publication number
- EA200870430A1 EA200870430A1 EA200870430A EA200870430A EA200870430A1 EA 200870430 A1 EA200870430 A1 EA 200870430A1 EA 200870430 A EA200870430 A EA 200870430A EA 200870430 A EA200870430 A EA 200870430A EA 200870430 A1 EA200870430 A1 EA 200870430A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- iii
- compound
- formula
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Изобретение обеспечивает способ лечения вирусной инфекции у человека, включающий введение эффективного количества соединения формулы I, II, III или IVили его фармацевтически приемлемой соли. Изобретение включает также способ ингибирования нейраминидазы у человека, предусматривающий введение эффективного количества соединения формулы I, II, III или IV или его фармацевтически приемлемой соли. Изобретение обеспечивает стандартную лекарственную форму, содержащую приблизительно до 500 мг соединения формулы I, II, III или IV или его фармацевтически приемлемой соли, и набор, содержащий соединение формулы I, II, III или IV или его фармацевтически приемлемую соль, и инструкции для введения этого соединения человеку внутримышечным путем. Изобретение обеспечивает применение соединения формулы I, II, III или IV или его фармацевтически приемлемой соли для увеличения продолжительности жизни и/или уменьшения смертности в группе млекопитающих подвергнутых воздействию источника вируса гриппа.The invention provides a method of treating a viral infection in humans, comprising administering an effective amount of a compound of formula I, II, III or IV, or a pharmaceutically acceptable salt thereof. The invention also includes a method of inhibiting neuraminidase in humans, comprising administering an effective amount of a compound of formula I, II, III or IV, or a pharmaceutically acceptable salt thereof. The invention provides a unit dosage form containing up to about 500 mg of a compound of formula I, II, III or IV, or a pharmaceutically acceptable salt thereof, and a kit containing a compound of formula I, II, III or IV, or a pharmaceutically acceptable salt thereof, and instructions for administering this connections to a person intramuscularly. The invention provides the use of a compound of formula I, II, III or IV, or a pharmaceutically acceptable salt thereof, to increase life expectancy and / or decrease mortality in a group of mammals exposed to a source of influenza virus.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2006/013535 WO2007117241A1 (en) | 2006-04-12 | 2006-04-12 | Intramuscular antiviral treatments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200870430A1 true EA200870430A1 (en) | 2009-06-30 |
Family
ID=37671157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200870430A EA200870430A1 (en) | 2006-04-12 | 2006-04-12 | INTRAMUSCULAR ANTIVIRUS METHODS OF TREATMENT |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP2009533428A (en) |
| CN (1) | CN104784166A (en) |
| AU (1) | AU2006341592A1 (en) |
| BR (1) | BRPI0621552A2 (en) |
| CA (1) | CA2649090A1 (en) |
| EA (1) | EA200870430A1 (en) |
| MX (1) | MX2008013140A (en) |
| WO (1) | WO2007117241A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0518443D0 (en) | 2005-09-09 | 2005-10-19 | Evolutec Ltd | Method of treating myasthenia gravis |
| CN101367750B (en) * | 2007-08-14 | 2012-05-23 | 中国人民解放军军事医学科学院毒物药物研究所 | (1S,2S,3S,4R)-3-[(1S)-1-acet-ammonia-2-ethyl-butyl]-4- guanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid aqua compound and medical uses thereof |
| JP5840623B2 (en) * | 2010-01-08 | 2016-01-06 | ヴォリューション イミュノ ファーマシューティカルズ エスエイ | EV576 for use in the treatment of respiratory tract viral infections |
| CN102584637B (en) * | 2011-01-17 | 2014-07-09 | 天津药物研究院 | Peramivir hydrate crystal, preparation method, medical compound and usage thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1040094T1 (en) * | 1997-12-17 | 2009-10-31 | Biocryst Pharm Inc | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| GB0015324D0 (en) * | 2000-06-22 | 2000-08-16 | Biota Scient Management | Medicaments |
-
2006
- 2006-04-12 EA EA200870430A patent/EA200870430A1/en unknown
- 2006-04-12 JP JP2009505338A patent/JP2009533428A/en active Pending
- 2006-04-12 BR BRPI0621552-1A patent/BRPI0621552A2/en not_active IP Right Cessation
- 2006-04-12 WO PCT/US2006/013535 patent/WO2007117241A1/en active Application Filing
- 2006-04-12 MX MX2008013140A patent/MX2008013140A/en not_active Application Discontinuation
- 2006-04-12 CA CA002649090A patent/CA2649090A1/en not_active Abandoned
- 2006-04-12 AU AU2006341592A patent/AU2006341592A1/en not_active Abandoned
-
2007
- 2007-02-12 CN CN201510115375.7A patent/CN104784166A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2008013140A (en) | 2009-02-12 |
| BRPI0621552A2 (en) | 2011-12-13 |
| WO2007117241A1 (en) | 2007-10-18 |
| AU2006341592A1 (en) | 2007-10-18 |
| CN104784166A (en) | 2015-07-22 |
| JP2009533428A (en) | 2009-09-17 |
| CA2649090A1 (en) | 2007-10-18 |
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