EA200800742A1 - METHOD OF INCREASING THE PERIOD OF SEMI-EXTRACTING OF DIINCRETATE ISOSORBIDE DURING CORONAR FAILURE IN EXPERIMENT - Google Patents
METHOD OF INCREASING THE PERIOD OF SEMI-EXTRACTING OF DIINCRETATE ISOSORBIDE DURING CORONAR FAILURE IN EXPERIMENTInfo
- Publication number
- EA200800742A1 EA200800742A1 EA200800742A EA200800742A EA200800742A1 EA 200800742 A1 EA200800742 A1 EA 200800742A1 EA 200800742 A EA200800742 A EA 200800742A EA 200800742 A EA200800742 A EA 200800742A EA 200800742 A1 EA200800742 A1 EA 200800742A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- experiment
- isosorbide
- increasing
- diincretate
- coronar
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Способ заключается в увеличении периода полувыведения изосорбида динитрата при коронарной недостаточности в эксперименте путем нанесения мицеллярной формы изосорбида динитрата на грудную клетку из расчета 1 мг/кг массы тела. При введении изосорбида динитрата в виде инъекций период полувыведения составил 0,52 ч, а при введении в виде мицеллярной формы - 8,2 ч, что является свидетельством увеличения периода полувыведения изосорбида динитратаThe method consists in increasing the half-life of isosorbide dinitrate for coronary insufficiency in the experiment by applying the micellar form of isosorbid dinitrate on the chest at the rate of 1 mg / kg body weight. With the introduction of isosorbide dinitrate as an injection, the half-life was 0.52 hours, and when administered as a micellar form, it was 8.2 hours, which is evidence of an increase in the half-life of isosorbide dinitrate
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200800742A EA017580B1 (en) | 2008-02-15 | 2008-02-15 | Method for increasing period of isosorbide dinitrate partial ejection in coronary insufficiency |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200800742A EA017580B1 (en) | 2008-02-15 | 2008-02-15 | Method for increasing period of isosorbide dinitrate partial ejection in coronary insufficiency |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200800742A1 true EA200800742A1 (en) | 2009-10-30 |
EA017580B1 EA017580B1 (en) | 2013-01-30 |
Family
ID=41353733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200800742A EA017580B1 (en) | 2008-02-15 | 2008-02-15 | Method for increasing period of isosorbide dinitrate partial ejection in coronary insufficiency |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA017580B1 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0748626B1 (en) * | 1994-02-28 | 2001-08-16 | Teijin Limited | Patch containing isosorbide dinitrate and prepared by using adhesive mixture |
RU2267318C1 (en) * | 2004-05-25 | 2006-01-10 | Закрытое акционерное общество "ФАРМАПЭК" | Prolonged antianginal preparation of isosorbide dinitrate and method for its obtaining |
-
2008
- 2008-02-15 EA EA200800742A patent/EA017580B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA017580B1 (en) | 2013-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |