EA200602065A1 - Радиосенсибилизатор - Google Patents

Радиосенсибилизатор

Info

Publication number
EA200602065A1
EA200602065A1 EA200602065A EA200602065A EA200602065A1 EA 200602065 A1 EA200602065 A1 EA 200602065A1 EA 200602065 A EA200602065 A EA 200602065A EA 200602065 A EA200602065 A EA 200602065A EA 200602065 A1 EA200602065 A1 EA 200602065A1
Authority
EA
Eurasian Patent Office
Prior art keywords
radio sensor
fatty acid
higher fatty
acyl residue
radiosensitizer
Prior art date
Application number
EA200602065A
Other languages
English (en)
Other versions
EA010292B1 (ru
Inventor
Иппэи Сакимото
Масахико Миура
Кейко Катаока
Кенго Сакагути
Фумио Сугавара
Кейсуке Охта
Такаюки Ямазаки
Original Assignee
Тойо Суйсан Кайся, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тойо Суйсан Кайся, Лтд. filed Critical Тойо Суйсан Кайся, Лтд.
Publication of EA200602065A1 publication Critical patent/EA200602065A1/ru
Publication of EA010292B1 publication Critical patent/EA010292B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Радиосенсибилизатор, содержащий в качестве активного ингредиента по меньшей мере один тип соединения, выбранного из группы, состоящей из соединения, представленного следующей общей формулой (1)где Rпредставляет собой ацильный остаток высшей жирной кислоты, a Rпредставляет собой атом водорода или ацильный остаток высшей жирной кислоты, и его фармацевтически приемлемую соль.
EA200602065A 2004-06-24 2005-06-24 Радиосенсибилизатор EA010292B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004186480 2004-06-24
JP2004374445 2004-12-24
PCT/JP2005/011630 WO2006001374A1 (ja) 2004-06-24 2005-06-24 放射線治療増感剤

Publications (2)

Publication Number Publication Date
EA200602065A1 true EA200602065A1 (ru) 2007-04-27
EA010292B1 EA010292B1 (ru) 2008-08-29

Family

ID=35781821

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200602065A EA010292B1 (ru) 2004-06-24 2005-06-24 Радиосенсибилизатор

Country Status (13)

Country Link
US (2) US20070219145A1 (ru)
EP (1) EP1734046B1 (ru)
JP (1) JP3927993B2 (ru)
KR (1) KR100832167B1 (ru)
CN (1) CN1972955B (ru)
AT (1) ATE479695T1 (ru)
AU (1) AU2005257359B2 (ru)
BR (1) BRPI0511824A (ru)
CA (1) CA2567306C (ru)
DE (1) DE602005023288D1 (ru)
EA (1) EA010292B1 (ru)
NO (1) NO20070421L (ru)
WO (1) WO2006001374A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101136601B1 (ko) * 2007-07-20 2012-04-23 토요 수이산 가부시키가이샤 신규한 술폰산화당 화합물 및 그 의약으로서의 사용
SG172979A1 (en) * 2009-01-16 2011-08-29 Toyo Suisan Kaisha Compound having tumor-resident property
JP6621158B1 (ja) * 2019-03-05 2019-12-18 株式会社エム・ティー・スリー 放射線増感剤
JP6903273B1 (ja) 2020-09-25 2021-07-14 株式会社エム・ティー・スリー 化合物又はその塩、及び放射性増感剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735516A (en) * 1980-08-11 1982-02-26 Yamasa Shoyu Co Ltd Agent for increasing radiosensitivity or agent for increasing effect of substance having activity similar to radiation
JPS5767518A (en) * 1980-09-17 1982-04-24 Yamasa Shoyu Co Ltd Radiosensitizing agent or agent for increasing effect of radiomimetic substance
NL8401337A (nl) * 1984-04-26 1985-11-18 Hoogovens Groep Bv Werkwijze voor het vervaardigen van cao-bevattende vuurvaste stenen.
DE3417230A1 (de) * 1984-05-10 1985-11-14 Metallgesellschaft Ag, 6000 Frankfurt Verfahren und vorrichtung zum entgasen von schwefelwasserstoffhaltigem fluessigem schwefel
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
JP2626727B2 (ja) * 1990-01-26 1997-07-02 ポーラ化成工業株式会社 ２―ニトロイミダゾール誘導体、その製造法及びこれを有効成分とする放射線増感剤
FR2733753B1 (fr) * 1995-05-02 2002-06-21 Cis Bio Int Derives iodes de monosaccharides utilisables comme produits radiopharmaceutiques
WO2000006244A2 (en) * 1998-07-30 2000-02-10 Hainfeld James F Loading metal particles into cell membrane vesicles and metal particle use for imaging and therapy
JP3851461B2 (ja) * 1998-09-04 2006-11-29 東洋水産株式会社 ピラノシドおよびその製造方法
JP2000212087A (ja) * 1999-01-20 2000-08-02 Fujimoto Brothers:Kk ニトロ―５―デアザフラビン誘導体を有効成分とする放射線増感剤。
EP1172107B1 (en) * 1999-02-26 2006-12-20 Toyo Suisan Kaisha, Ltd. Drugs containing sulfopyranosylacylglycerol derivatives
US6518410B2 (en) * 1999-02-26 2003-02-11 Toyo Suisan Kaisha, Ltd. Sulfoquinovosylacylglycerol derivative, and use thereof as medicaments
KR100435416B1 (ko) * 1999-02-26 2004-06-09 토요 수이산 가부시키가이샤 신규 술포푸코실아실글리세롤유도체 및 그 의약으로서의용도
ATE244568T1 (de) * 1999-02-26 2003-07-15 Toyo Suisan Kaisha Sulforhamnosylacylglycerin-derivate und ihre verwendung als medikamente
KR20030071029A (ko) * 2002-02-27 2003-09-03 주식회사 팜제니아 항암제 및 방사선 치료 증진제로서 유용한 조성물

Also Published As

Publication number Publication date
NO20070421L (no) 2007-01-23
KR20070020270A (ko) 2007-02-20
WO2006001374A1 (ja) 2006-01-05
EA010292B1 (ru) 2008-08-29
JP3927993B2 (ja) 2007-06-13
DE602005023288D1 (de) 2010-10-14
AU2005257359B2 (en) 2009-01-22
BRPI0511824A (pt) 2007-12-26
US20070219145A1 (en) 2007-09-20
CA2567306C (en) 2011-06-07
ATE479695T1 (de) 2010-09-15
JPWO2006001374A1 (ja) 2008-04-17
EP1734046B1 (en) 2010-09-01
CN1972955A (zh) 2007-05-30
EP1734046A4 (en) 2009-01-07
EP1734046A1 (en) 2006-12-20
CN1972955B (zh) 2010-08-25
KR100832167B1 (ko) 2008-05-23
AU2005257359A1 (en) 2006-01-05
US20090253644A1 (en) 2009-10-08
CA2567306A1 (en) 2006-01-05

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU