EA200600622A1 - MEANS, possessing antiviral activity, and the method of its production - Google Patents
MEANS, possessing antiviral activity, and the method of its productionInfo
- Publication number
- EA200600622A1 EA200600622A1 EA200600622A EA200600622A EA200600622A1 EA 200600622 A1 EA200600622 A1 EA 200600622A1 EA 200600622 A EA200600622 A EA 200600622A EA 200600622 A EA200600622 A EA 200600622A EA 200600622 A1 EA200600622 A1 EA 200600622A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- rimantadine
- sodium alginate
- antiviral activity
- temperature
- complex
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относится к медицине, более точно к фармацевтической промышленности, и может быть использовано в промышленной технологии производства препарата для профилактики и лечения вирусных заболеваний различной этиологии. Способ получения средства, обладающего противовирусной активностью, на основе комплекса римантадина и альгината натрия, заключается в том, что римантадин растворяют при температуре 55-65°С в воде, затем в охлажденный до 15-35°С раствор вводят низкомолекулярный альгинат натрия (вязкость 1% раствора в воде 9-26 мПа∙с) при условии, что массовое соотношение римантадин - альгинат натрия составляет (0,56-0,64):1, оставляют набухать в течение 5-10 ч, а затем диспергируют при температуре 15-35°С в течение 30-60 мин высокоскоростной мешалкой до образования стабильного коллоидного раствора солевого комплекса с последующим введением его при температуре 60-80°С в раствор сахара, окрашенный с помощью пищевого красителя. Средство, обладающее противовирусной активностью, на основе комплекса римантадина и альгината натрия получено заявленным способом и содержит исходные компоненты в 100 мл препарата в следующем соотношении, г:The invention relates to medicine, more specifically to the pharmaceutical industry, and can be used in industrial production technology of the drug for the prevention and treatment of viral diseases of various etiologies. The method of obtaining an agent with antiviral activity, based on a complex of rimantadine and sodium alginate, is that rimantadine is dissolved at a temperature of 55-65 ° C in water, then low-molecular-weight sodium alginate (viscosity 1 % solution in water 9-26 MPa ∙ s) provided that the mass ratio of rimantadine - sodium alginate is (0.56-0.64): 1, is left to swell for 5-10 hours, and then dispersed at a temperature of 15- 35 ° C for 30-60 minutes with a high-speed mixer until stable colloidal solution of a complex salt, followed by introducing it at a temperature of 60-80 ° C in a solution of sugar, colored by a food dye. The tool with antiviral activity, based on the complex of rimantadine and sodium alginate obtained by the claimed method and contains the original components in 100 ml of the drug in the following ratio, g:
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200600622A EA200600622A1 (en) | 2006-04-19 | 2006-04-19 | MEANS, possessing antiviral activity, and the method of its production |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200600622A EA200600622A1 (en) | 2006-04-19 | 2006-04-19 | MEANS, possessing antiviral activity, and the method of its production |
Publications (2)
Publication Number | Publication Date |
---|---|
EA007919B1 EA007919B1 (en) | 2007-02-27 |
EA200600622A1 true EA200600622A1 (en) | 2007-02-27 |
Family
ID=42121397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200600622A EA200600622A1 (en) | 2006-04-19 | 2006-04-19 | MEANS, possessing antiviral activity, and the method of its production |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA200600622A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2443410C1 (en) * | 2011-01-19 | 2012-02-27 | Михаил Константинович Кузьмич | Method for preparing antiviral agents (versions) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2381807C1 (en) * | 2008-07-18 | 2010-02-20 | Алексей Глебович Одинец | Antiviral agent |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01197437A (en) * | 1988-01-29 | 1989-08-09 | Dso Pharmachim | Antiviral agent |
EP0324875A1 (en) * | 1988-01-20 | 1989-07-26 | S O "Pharmachim" | Anti-virus drug |
RU2185822C2 (en) * | 2000-08-01 | 2002-07-27 | Общество с ограниченной ответственностью "Фармаген" | Preparation for treatment and prophylaxis of viral diseases |
-
2006
- 2006-04-19 EA EA200600622A patent/EA200600622A1/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2443410C1 (en) * | 2011-01-19 | 2012-02-27 | Михаил Константинович Кузьмич | Method for preparing antiviral agents (versions) |
Also Published As
Publication number | Publication date |
---|---|
EA007919B1 (en) | 2007-02-27 |
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