EA200501577A1 - DERIVATIVES 4- (2-PHENYLSULPHANYLPHENYL) PIPERIDINE AS SEROTONIN REDUCING INHIBITORS - Google Patents
DERIVATIVES 4- (2-PHENYLSULPHANYLPHENYL) PIPERIDINE AS SEROTONIN REDUCING INHIBITORSInfo
- Publication number
- EA200501577A1 EA200501577A1 EA200501577A EA200501577A EA200501577A1 EA 200501577 A1 EA200501577 A1 EA 200501577A1 EA 200501577 A EA200501577 A EA 200501577A EA 200501577 A EA200501577 A EA 200501577A EA 200501577 A1 EA200501577 A1 EA 200501577A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- phenylsulphanylphenyl
- serotonin
- piperidine
- derivatives
- reducing inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относится к соединениям, представленным общей формулой (I), в которой заместители определены в описании заявки. Соединения полезны при лечении аффективных расстройств, таких как депрессия, тревожных расстройств, включающих генерализованное тревожное состояние, паническое расстройство и обсессивно-компульсивное расстройство.The invention relates to compounds represented by the general formula (I) in which the substituents are defined in the application description. The compounds are useful in treating affective disorders such as depression, anxiety disorders, including generalized anxiety, panic disorder, and obsessive-compulsive disorder.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200300520 | 2003-04-04 | ||
PCT/DK2004/000244 WO2004087156A1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200501577A1 true EA200501577A1 (en) | 2006-04-28 |
EA010869B1 EA010869B1 (en) | 2008-12-30 |
Family
ID=36091716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200501577A EA010869B1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenylsulfanyl-phenyl) piperidine derivatives as serotonin reuptake inhibitors |
Country Status (10)
Country | Link |
---|---|
KR (1) | KR101107536B1 (en) |
CN (1) | CN1780622A (en) |
AR (1) | AR043965A1 (en) |
BR (1) | BRPI0408647A (en) |
CL (1) | CL2004000725A1 (en) |
EA (1) | EA010869B1 (en) |
IS (1) | IS2676B (en) |
NZ (1) | NZ541859A (en) |
UA (1) | UA81472C2 (en) |
ZA (1) | ZA200507181B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200932225A (en) * | 2007-12-14 | 2009-08-01 | Lundbeck & Co As H | 4-[2,3-difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine |
CN105348204B (en) * | 2015-11-18 | 2018-09-14 | 乳源瑶族自治县大众药品贸易有限公司 | 1- heterocycles -2- (Heteroarylthio) benzene derivatives and its application method and purposes |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
US4198419A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenylthiophenylpiperidines |
PL355289A1 (en) * | 1999-10-13 | 2004-04-05 | Pfizer Products Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
UA81749C2 (en) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Derivated of phenylpiperazine as serotonin reuptake inhibitorS |
-
2004
- 2004-04-02 NZ NZ541859A patent/NZ541859A/en not_active IP Right Cessation
- 2004-04-02 ZA ZA200507181A patent/ZA200507181B/en unknown
- 2004-04-02 CL CL200400725A patent/CL2004000725A1/en unknown
- 2004-04-02 EA EA200501577A patent/EA010869B1/en not_active IP Right Cessation
- 2004-04-02 CN CNA2004800091749A patent/CN1780622A/en active Pending
- 2004-04-02 KR KR1020057018872A patent/KR101107536B1/en not_active IP Right Cessation
- 2004-04-02 UA UAA200509599A patent/UA81472C2/en unknown
- 2004-04-02 BR BRPI0408647-3A patent/BRPI0408647A/en not_active IP Right Cessation
- 2004-04-02 AR ARP040101131A patent/AR043965A1/en not_active Application Discontinuation
-
2005
- 2005-08-22 IS IS7996A patent/IS2676B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200507181B (en) | 2007-03-28 |
IS2676B (en) | 2010-09-15 |
BRPI0408647A (en) | 2006-03-07 |
AR043965A1 (en) | 2005-08-17 |
UA81472C2 (en) | 2008-01-10 |
CL2004000725A1 (en) | 2005-02-18 |
NZ541859A (en) | 2008-10-31 |
IS7996A (en) | 2005-08-22 |
KR20050119681A (en) | 2005-12-21 |
KR101107536B1 (en) | 2012-01-31 |
EA010869B1 (en) | 2008-12-30 |
CN1780622A (en) | 2006-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY RU |