EA040318B1 - COMPOSITIONS FOR AGRICULTURAL APPLICATION - Google Patents

Description

The invention relates to a granular composition for use in agriculture. More specifically, the invention relates to a water-disintegrating granular composition containing at least one agrochemically active substance and one or more agrochemically acceptable excipients. The agrochemical active is selected from crop or algae nutrients or a pesticidal active. The water-degradable granular composition, in particular, has a particle size of 0.1 to 50 µm, a bulk density of less than 1.5 g/ml and a hardness of at least 1 N. The invention further relates to a method for producing a water-degradable a granular composition containing one or more water-insoluble nutrients or algae or pesticide actives. The invention also relates to a method for treating plants or soil with a water-degradable granular composition.

Prior Art

For several years, nutrients or fertilizers and pesticides for crops are applied to the soil. They are available in well-known granular forms such as pellets, water-dispersible granules or wettable powders, pastilles containing bentonite.

There is a big problem with some nutrients or fertilizers for crops, which, when applied, are quickly washed out of the soil due to their rapid mobility in the soil or their aggregation and characteristics. The leached out nutrients can contaminate groundwater in regions with intensive agriculture. In humid climates, nutrient leaching occurs to a certain extent even with natural growth, but agricultural activities can greatly increase leaching losses.

One study on sandy soils found that leaching sulfur losses ranged from 35 to 83 kg/ha, depending on the different types of sulfur used for fertilization. It is also known that the lack of sulfur in the soil reduces the use of available nitrogen in the soil, thereby increasing the leaching of nitrates (Likkineni and Abrol, 1994).

Therefore, it is important to ensure that the plant takes up these nutrients at the appropriate stage and, in addition, to ensure that the crops or plants take up the nutrients throughout the life cycle of the crops, while preventing or reducing nutrient leaching after application. One of the biggest problems in the use of known compositions is to ensure adequate release of the active or nutrients, as well as providing the necessary active for uptake by the plants over a long period of the crop life cycle. Similarly, pesticides that are applied to the soil do not remain in the soil for long periods when pests or diseases appear, and there is a need to provide pesticides slowly over a period of time and minimize losses due to pests or diseases. In addition, previously known granular pesticide compositions tend to leach out due to their rapid dispersion, whereby leached out pesticides contaminate groundwater in regions of intensive agriculture.

Water-dispersible granules as such have been described in US 8241387 and WO 2012131702 and have been known for a very long time. While these granules provide instant nutrients, they have poor abrasion resistance and very low hardness. While these documents describe granules ranging in size from 0.1 to 2.5 mm and 0.75 to 5 mm, respectively, it has been observed that these granules do not actually retain their integrity, including their size and shape, and do not have a mechanical strength that allows them to withstand operations with them after manufacture, and are destroyed to fine dust. It has been observed that attrition that occurs during the manufacture, packaging, storage, handling and use of these granules or powders results in premature degradation of these compositions resulting in a significant loss of release control and excessive leaching of nutrients. In addition, one of the biggest problems with such water-dispersible granules is their application and labor dependency. When applied through mechanical applicators (bunkers and drilling devices), such compositions are released in one place; they are extremely difficult to evenly distribute using mechanized means. Farmers tend to apply mixtures of fertilizers in one go. However, due to their shape, these water-dispersible granules must be applied separately from other granular fertilizers such as urea. This makes them inconvenient to apply and increases the cost of application for the farmer.

In addition, both powder and granular formulations tend to wash out due to their immediate and complete dispersibility in water (see column C, FIG. 5).

Granular plant nutrient compositions are also known, such as those formed from bentonite clay. Brimstone 90, Tiger 90, Growmor, Vitsul and others are some of the traditional brands available on the market. However, these pellets have a high bulk density, high particle size, and do not disperse or disintegrate properly when exposed to

- 1 040318 canopies into the soil. They also do not provide nutrients when the crops need them. These pellets take a long time to digest in the soil or sometimes remain intact or as residue in the soil even after harvest. As a result, they do not provide enough nutrients to crops, thereby making it difficult to feed crops in the early and growing seasons. In addition, these compositions also need to be used at very high doses. After all, the use of these traditional pellets leads to lower crop yields at a high cost for the farmer to use them.

In addition, biological materials such as algae, bacteria, and others are useful alternatives to chemical agents to improve and maintain soil nutrients. Granulated compositions with an outer coating of biological materials are also known. WO 2016113665 describes pellets with an easily deformable core, a binder and an outer coating. The coating consists of two parts - the first layer contains biological material, and the second layer contains a specific desiccant or binder. Thus, this entire granular composition, due to its large particle size and coating layers, is characterized by poor dispersion and suspension and, ultimately, poor efficiency. It is noted that, since it swells in water and is practically not dispersed, it cannot adequately provide the culture with biological matter. Thus, biomaterial compositions should be optimized and improved in their application in order to provide a cost-effective result for the farmer in terms of yield, plant growth, viability and energy, as well as reduce the burden on the environment.

To date, all known compositions of agricultural actives or crop nutrients or biological materials, when applied to the soil, have disadvantages in application, inability to provide adequate nutrition and pest control throughout the life cycle of crops, and losses due to leaching. .

There continues to be a problem with providing agrochemical or agricultural nutrients or biological material or pesticidal actives in a form that allows for immediate uptake of the nutrient or agrochemical or pesticide and throughout the crop cycle.

Thus, the creation of less bulky, less thick dry agricultural compositions, while maintaining a large size and proper abrasion resistance for ease of use even when a large amount of insoluble material is included, but with proper dispersibility or disintegration properties, is a big problem. Another challenge is to develop a composition that also remains suspended in the water column for a certain period of time to facilitate uniform application to the soil. For example, it has been found that, over a period of time, previously known compositions of water-dispersible granules or microgranules are not resistant to wear, do not retain their structure and turn into micron particles during packaging and storage. As a result, these known compositions cannot be uniformly applied over large fields by means of mechanical applicators.

There is a need to provide dry agricultural compositions that can be applied with mechanical applicators along with other water soluble fertilizers such as urea and minimize their application costs. There is also a need to ensure that plant nutrients, algae or pesticide actives are instantly and continuously available to plants during the growth stages of the crop life cycle to ensure adequate nutrition, protein synthesis and plant protection. There is also a need to reduce washout losses.

The inventor was surprised to find that a composition containing an agrochemical active substance such as a water-insoluble nutrient or algae or pesticides in a dry, water-disintegrating, granular form with a fine particle distribution, a well-defined low bulk density, as well as a high abrasion resistance and hardness, proper suspending, dispersing and disintegrating properties in water and soil, as well as a certain residue on the sieve, the wet sieving method, surprisingly, for the first time allows to significantly increase not only the yield of plants in terms of grain yield or oil content but also markedly improve plant nutrient uptake along with improved plant physiological characteristics such as plant height, root length and improved leaf area, and enhance soil pest and disease control with the composition of the present invention. retention. While known compositions provide nutrients instantly, they are still washed out of the soil and cannot provide fertilizer requirements until later in the crop cycle. Surprisingly, it has been observed that the composition of the present invention makes water-insoluble nutrients or algae or pesticides available instantly and over a longer crop cycle period, providing immediate and sustained release of water-insoluble

- 2 040318 nutrients, algae or pesticides that provide nutrition and protection for crops at every stage of cultivation.

The essence of the invention

The invention relates to a water-disintegrating granular composition that is used in agriculture and contains at least one agrochemical substance; at least one agrochemically acceptable excipient; while the size of the granules of the composition is from 0.1 to 6 mm and contains particles ranging in size from 0.1 to 50 microns. The composition has a hardness of at least 1 N, but a bulk density of less than 1.5 g/ml. The composition also has the proper physical properties of disintegration, dispersion and suspension, optimal release properties throughout the entire life cycle of the culture. The inventor has unexpectedly found that a composition with the above parameters of bulk density, hardness and particle size distribution provides instantaneous as well as continuous release of agrochemicals throughout the entire cycle of growing crops. In addition, the composition exhibits surprisingly high efficacy at significantly reduced application doses.

The invention relates to a water-disintegrating granular composition that is used in agriculture and contains at least one water-insoluble nutrient; at least one agrochemically acceptable excipient; while the size of the granules of the composition is from 0.1 to 6 mm and contains particles ranging in size from 0.1 to 50 microns. It was unexpectedly noted that the composition not only has a hardness of at least 1 N, but also a bulk density of less than 1.5 g/ml.

According to an embodiment of the invention, it also relates to a process for preparing a water-disintegrating granular composition, comprising grinding a mixture of at least one water-insoluble nutrient and at least one agrochemically acceptable excipient to obtain a wet mixture in the form of a suspension. The process further includes drying the wet mixture or slurry to form a powder or granules. The obtained granules are further subjected to agglomeration or granulation to obtain a granular composition with one or more water-insoluble nutrients. The granular composition for agricultural use thus obtained has a hardness of at least 1 N and a bulk density of less than 1.5 g/ml, with a granule size of 0.1 to 6 mm and a particle size of 0.1 to 50 µm.

According to an embodiment of the invention, it also relates to the use of a water-disintegrable granular composition of water-insoluble nutrients in the form of a composition with at least one nutrient, a fertilizer composition, a plant strengthening composition, a soil improver composition and a yield increasing composition.

According to an embodiment of the invention, it also relates to a method for improving plant health, comprising treating the plant itself or plant propagation material, or seeds, or seedlings, or surrounding soil, with a water-disintegrating granular composition containing at least one water-insoluble nutrient. and at least one agrochemically acceptable excipient; while the granules have a size of 0.1 to 6 mm, abrasion resistance of at least 50% and a hardness of at least 1 N.

The invention also relates to a water-disintegrating granular algal composition for use in agriculture. More specifically, the invention relates to a water-disintegrating granular algal composition containing at least one algae and at least one agrochemically acceptable excipient. Even more specifically, the invention relates to a water-disintegrating granular composition containing at least one algae and at least one agrochemically acceptable excipient, wherein the granule size of the composition is from 0.1 to 6 mm, the particle size is from 0. 1 to 50 µm, the composition has a hardness of at least 1 N and a bulk density of less than 1.5 g/ml. The composition also has the proper physical properties of disintegration, dispersion and suspension, optimal release properties throughout the entire life cycle of the culture. In addition, the composition exhibits surprisingly high efficacy at significantly reduced doses used.

According to an embodiment of the invention, it also relates to a method for preparing a water-disintegrating granular composition containing at least one algae and at least one agrochemically acceptable excipient, comprising grinding a mixture consisting of at least one algae and at least one agrochemically acceptable auxiliary substance to obtain a wet mixture in the form of a suspension. The method further includes drying the wet mixture to obtain granules. The resulting granules are further subjected to agglomeration or granulation to obtain a granular composition with one or more algae. The granular composition for agricultural use thus obtained has a bulk density of less than 1.5 g/ml and a hardness of at least 1 N, with a particle size of 0.1 to 50 µm and a granule size of 0.1 to 6 mm.

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According to an embodiment of the invention, it also relates to the use of a water-degradable granular algae composition that contains a nutrient or plant fortifier or ameliorant and yield enhancer.

According to an embodiment of the invention, it also relates to a method for improving plant health comprising treating a plant or plant propagation material or seed or seedling or surrounding soil with a water-disintegrating granular algal composition comprising at least one algae and at least one agrochemically acceptable excipient; while the granules have a hardness of at least 1 N and a bulk density of less than 1.5 g/ml.

The invention also relates to a water-disintegrating granular composition for agricultural use containing at least one pesticidal active substance; at least one agrochemically acceptable excipient; the size of the granules of the composition is from 0.1 to 6 mm and the particle size is from 0.1 to 50 microns. It was unexpectedly noted that the composition not only has a hardness of at least 1 N, but also a bulk density of less than 1.5 g/ml.

According to an embodiment of the invention, it also relates to a process for preparing a granular composition for agricultural use, comprising grinding a mixture of at least one pesticidal active and at least one agrochemically acceptable adjuvant to obtain a wet mixture in the form of a suspension. The process further includes drying the suspension to obtain granules. The resulting granules are further subjected to agglomeration or granulation to obtain a granular composition with one or more pesticidal active substances for agricultural use. The thus obtained granular composition of pesticidal active substances for agricultural use has a hardness of at least 1 N and a bulk density of less than 1.5 g/ml, with a granule size of 0.1 to 6 mm and a particle size of 0.1 to 50 µm.

According to an embodiment of the invention, it also relates to the use of a granular composition containing at least one pesticidal active as a plant protection composition.

According to an embodiment of the invention, it also relates to a plant protection method comprising treating a plant or plant propagation material or seed or seedling or surrounding soil with a water-disintegrating granular composition comprising at least one pesticidal active and at least at least one agrochemically acceptable excipient; while the granules have a size of 0.1 to 6 mm, a bulk density of less than 1.5 g/ml and a hardness of at least 1 N.

Brief description of graphic materials

For a more complete understanding of the invention, reference should now be made to the embodiments illustrated in greater detail in the accompanying drawings and described as embodiments of the invention.

In FIG. 1 depicts a water-degradable granular composition containing water-degradable granules, 90% sulfur, according to an embodiment of the present invention.

In FIG. 2 shows a water-dispersible granular 90% sulfur composition after packaging and transport as described in WO 2008084495. The image shows a significant crumbling of the granules into smaller particles during manufacture, processing, packaging and transport, due to low abrasion resistance and low hardness these granules.

In FIG. 3 shows a water degradable granular composition of sulfur 70% + zinc oxide 15% according to an embodiment of the present invention.

In FIG. 4 shows a water-dispersible granular composition of sulfur 70% + zinc oxide 15% after packaging and transport, as described in WO 2012131702. FIG. 4 also shows a significant crumbling of the granules into small particles as a result of manufacturing, processing, packaging and transportation, which is due to poor abrasion resistance and low hardness of these granules, as can be seen from table. 7.

In FIG. 5 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and water-dispersible sulfur granules 90%, as described in WO 2008084495 (C), in water, immediately after the first application (time 0).

In FIG. 6 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art water-dispersible 90% sulfur granules as described in WO 2008084495 (C), in water, after 15 minutes, without agitation.

In FIG. 7 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art 90% sulfur water-dispersible granules as described in WO

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2008084495 (C), in water, after 30 min, without stirring.

In FIG. 8 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art 90% sulfur water-dispersible granules as described in WO

2008084495 (C), in water, after 1 h, without stirring.

In FIG. 9 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art water-dispersible 90% sulfur granules as described in WO 2008084495 (C), in water, after 2 hours, without agitation.

In FIG. 10 shows prior art 90% sulfur bentonite granules (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art water-dispersible 90% sulfur granules as described in WO 2008084495 (C), in water, after 4 hours, without agitation.

In FIG. 11 shows prior art 90% sulfur bentonite pellets (A) in water; water-degradable sulfur granules 90% according to embodiment (B) in water; and prior art water-dispersible 90% sulfur granules as described in WO 2008084495 (C), in water, after 24 hours, without agitation.

Description of the invention

In describing an embodiment of the invention, specific terminology has been chosen for clarity. However, the invention is not intended to be limited to the specific terms chosen, and each specific term is to be understood to include all technical equivalents that are used in a similar manner to achieve a similar purpose. For example, in the context of the present invention, the term agrochemical active includes not only a chemical plant nutrient or water-insoluble nutrient or plant protection or pesticidal active but also biological material such as algae and bacterial material.

The invention relates to a water-disintegrating granular composition for agricultural use, which contains at least one water-insoluble nutrient and at least one agrochemically acceptable excipient. The water-disintegrating granules are 0.1 to 6 mm in size and include particles ranging in size from 0.1 to 50 µm.

According to another embodiment, the granules of the composition for agricultural use have a size of 0.1 to 6 mm. According to another embodiment, the granules of the composition for agricultural use have a size of 0.5 to 6 mm. According to another embodiment, the granules of the composition for agricultural use have a size of 1 to 6 mm. According to another embodiment of the invention, the granules for agricultural use are 1 to 5 mm in size. According to another embodiment of the invention, the granules for agricultural use are 2 to 5 mm in size.

According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 50 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 40 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 30 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 20 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 15 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 10 microns.

According to an embodiment of the invention, the water-insoluble nutrient includes a water-insoluble fertilizer or micronutrient. According to an embodiment of the invention, the water-insoluble nutrient comprises a mixture of one or more water-insoluble fertilizers and one or more micronutrients, or salts or derivatives thereof, or complexes thereof. According to an embodiment of the invention, the water-insoluble fertilizer is at least one of a single nutrient fertilizer, a multi-component fertilizer, a two-component fertilizer, fertilizer compounds, organic fertilizers, derivatives or mixtures thereof. However, those skilled in the art will appreciate the possibility of using other known fertilizers without departing from the scope of the invention. In an embodiment, the water-insoluble fertilizer is one or more nitrate, phosphate, and potash fertilizers, or sulfate fertilizers such as elemental sulfur.

According to an embodiment of the invention, the water-insoluble nutrient includes, among others, boron, calcium, chlorine, chromium, cobalt, copper, fluorine, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, silicon, sodium, zinc in their elemental form or in the form of a salt or derivatives of these elements.

According to an embodiment of the invention, the water-insoluble nutrient comprises one or more elemental boron, boron carbide, boron nitride, alumina, aluminum dodecaboride, aluminum hydroxide, bauxite, calcite limestone, calcium oxalate, chromium oxide, cobalt oxide, cobalt sulfate, cobalt molybdate , cobalt carbonate, copper oxalate, copper oxide, copper sulfide, copper hydroxide, copper sulfide, copper phosphate, copper molybdate, fluorine oxide, fluorine molybdate, iron oxide, iron sulfide, magnesium oxide, magnesium hydroxide, magnesium orthophosphate, magnesium molybdate, magnesium carbonate, manganese oxide, manganese molybdate, molybdenum acetate, molybdenum disulfide, selenium sulfide, silicon nitride, zinc sulfide, zinc oxide, zinc carbonate, zinc phosphate, zinc molybdate, tomasslag, elemental chromium, chromium phosphate, iron sucrat, cobalt phosphide, cobalt cyanide, elemental nickel, nickel oxide, nickel oxyhydroxide, nickel carbonate, nickel chromate, nickel hydroxide, millerite, nickel selenide, phosphite nickel, elemental copper, insoluble copper cyanide, chalcosine, copper selenide, copper phosphide, covelline, copper arsenate, elemental argentum, elemental zinc, zinc chromate, zinc pyrophosphate, tin hydroxide, tin oxide and tin sulfide, their salts, derivatives and their combinations. However, those skilled in the art will appreciate the possibility of using other water-insoluble nutrients without departing from the scope of the invention.

According to an embodiment of the invention, the water-insoluble nutrient may be a vitamin. For example, but not limited to, it can be vitamin A, vitamin B, vitamin C, vitamin D, vitamin E, and vitamin K. However, those skilled in the art will appreciate the possibility of using other vitamins without departing from the scope of this invention.

According to an embodiment of the invention, the water-insoluble nutrient is present in a concentration range of at least 0.1% by weight of the total composition. According to an embodiment of the invention, the water-insoluble nutrient is present in a concentration range of less than 1% by weight of the total composition. According to an embodiment of the invention, the water-insoluble nutrient is present in a concentration range of less than 5% by weight of the total composition. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 10%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 20%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 30%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 40%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 50%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 60%. According to another embodiment of the invention, the water-insoluble nutrient is present in an amount of at least 70%. According to another embodiment of the invention, the composition contains at least 80% by weight of a water-insoluble nutrient. According to another embodiment of the invention, the composition contains at least 90% by weight of a water-insoluble nutrient. According to another embodiment of the invention, the composition contains at least 95% by weight of a water-insoluble nutrient.

The invention also relates to a water-disintegrating granular agricultural composition containing at least one algae and at least one agrochemically acceptable excipient. The water-disintegrating granules are 0.1 to 6 mm in size and include particles ranging in size from 0.1 to 50 µm.

According to another embodiment, the granules of the water-disintegrating granular composition for agricultural use are 0.1 to 6 mm in size. According to another embodiment, the granules of the composition for agricultural use have a size of 0.5 to 6 mm. According to another embodiment, the granules of the composition for agricultural use have a size of 1 to 6 mm. According to another embodiment of the invention, the granules for agricultural use are 1 to 5 mm in size. According to another embodiment of the invention, the granules for agricultural use are 2.5 to 5 mm in size.

According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 50 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 40 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 30 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 20 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 15 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 10 microns.

In another embodiment, the algae may be microalgae, marine or freshwater algae, or species, derivatives, or mixtures thereof.

According to another embodiment of the invention, the algae may be at least one of the group of green algae, red algae, golden algae, brown algae, golden brown algae, blue algae or blue-green algae, Asian flat algae or algae or derivatives thereof. , species and mixtures.

According to a further embodiment of the invention, algae may be at least one of the varieties

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Cyanobacteria (Cyanophyta), Ochrophytes, Glaucophytes, Pyrrophytes, Rhodophytes, Chrysophyta,

Raphidophytes, Eustigmatophytes, Synurophytes, Silicoflagellates, Sarcinochrysophyceae,

Heterokonts, Crytophytes, Haptophytes, Euglenophytes, Chiorophytes, Charophytes, Land

Plants, Embrophyta or Chlorarachniophytes or their derivatives, species and mixtures. However, those skilled in the art will appreciate the ability to use any other algae known in the art from other sections without departing from the scope of the invention.

According to a further embodiment of the invention, algae may be at least one of the family

Bryopsidaceae, Acrotylaceae, Areschougiaceae, Phaeophyceae, Cystocloniaceae, Dicranemataceae, Hypneaceae, Raphidiophyceae, Eustigmatophyceae Dumontiaceae, Caulerpaceae, Codiaceae, Halimedaceae, Udoteaceae, Anadyomenaceae, Polyphysaceae, Siphonocladoseaceae, Valoniaceae, Ulvidiaceae, Chordariaceae, Punctariaceae, Dicty,aceae, Cystocaraceae, Ectocariaceae , Sargassaceae, Sporochnaceae, Sphacelariaceae, Scytosiphonaceae, Sarcinochrysophyceae, Alariaceae, Gracilariaceae, Rhizophyllidaceae, Porphyridiaceae, Acrochaetiaceae, Bonnemaisoniaceae, Ceramiaceae, Dasyaceae, Rhodomelaceae, Delesseriaceae, Phacelocarpaceae, Halymeniaceae, Liagoraceae, Chrysomonadales, Chrysocapsales, Chrysosphaerales, Chrysotrichales, Heterokontae, Diatomeae, Galaxauraceae , Plocamiaceae, Champiaceae, Sebdeniaceae, Lomentariaceae, Peyssonneliaceae, Nizymeniaceae, Kallymeniaceae, Corallinaceae, Nemastomataceae, Xanthophyceae or their derivatives, species and mixtures. However, those skilled in the art will appreciate the ability to use any other algae known in the art from other families without departing from the scope of the invention.

According to a further embodiment of the invention, the algae may be at least one of the genus

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Spirulina Sp., Nitzschia Sp., Navicula Sp., Ahnfeltia Sp., Anikstrodesmis Sp., Arthrospira Sp., Nannochloris Sp. Asteromenia Sp., Botryocladia Sp., Chlorella Sp., Haematococcus Sp., Dunaliella Sp., Selenasirum Sp., Nannochhropsis Sp., Scenedesm Sp., Graciaria Sp., Oscillatoria Sp., Phormidium Sp., Nemastoma Sp., Amphora Sp. ., Oehromonas Sp. Cyanidioschyzon Sp., Caulerpa Sp., Dictyosphaeria Sp., Haliptilon Sp., Atractophora Sp., Valonia Sp., Boodlea Sp., Gelidiella Sp., Ceratodictyon Sp., Pneophyllum Sp., Kallymenia Sp., Predaea Sp, Siphonocladus Sp. ., Cladophoropsis Sp., Amphiplexia Sp., Lemanea Sp., Mesophyllum Sp., Palmaria Sp., Cladosiphon Sp., Schmitzia Sp., Colpomenia Sp., Cryptophycees Sp., Metagoniolithon Sp., Hydrolithon Sp., Hypoglossum Sp., Seirospora Sp., Jania Sp., Florideophyceae Sp., Metamastophora Sp., Amphiroa Sp., Acanthophora Sp., Chondrus Sp., Cottoniella Sp., Pleonosporium Sp., Ditria Sp., Endosiphonia Sp., Doxodasya Sp., Drewiana Sp. ., Dictyomenia Sp., Antithamnion Sp., Platysiphonia Sp., Heterodoxia Sp., Dasyclonium Sp., Chondria Sp., Haraldiophyllum Sp., Aglaothamnion Sp., Struvea Sp., Sarcomenia Sp., Acrothamnion Sp., Martensia Sp., Lejolisia Sp., Haloplegma Sp., Griffithsia Sp., Glaphrymenia Sp., Dasya Sp., Acrosorium Sp., Spyridia Sp., Hemineura Sp., Wrangelia Sp., Trithamnion Sp., Dasyphila Sp., C laudea Sp., Corallophila Sp., Perischelia Sp., Monosporus Sp., Carpothamnion Sp., Guiryella Sp., Gattya Sp., Mastocarpus Sp., Anotrichium Sp., Centroceras Sp., Ceramium Sp., Caulerpa Sp., Vanvoorstia Sp. ., Euptilocladia Sp., Titanophora Sp., Tanakaella Sp., Asparagopsis Sp., Lithophyllum Sp., Acrochaetium Sp., Euptilota Sp., Audouinella Sp., Botryococcus Sp., Actmanthes Sp., Ahnfeltiopsis Sp., Agmenemum Sp., Cochlodinium Sp., Amphiprora Sp., Anftistrodesmus Sp., Ammsirodesnms Sp., Borodinetta Sp., Carteria Sp.,

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Stylonema Sp., Chaetoceros Sp., Chlamydomas Sp., Chlorococcuni Sp., Chlorogoni Sp., Chroomonas Sp., Chrysosphaera Sp., Ciicosphaera Sp., Crypthecodinium Sp., Cryptomonas Sp., Cyclotella Sp., Dimaliella Sp., Eremosphaera Sp. ., Ellipsoidon Sp., Euglena Sp., Franceia Sp., Gloeocapsa Sp., Fragilaria Sp., Gleocapsa Sp., Gloeothamnion Sp., Cyanospira Sp., Hymenomonas Sp., Bockrysis Sp., Hochrysis Sp., Lepocinclis Sp., Stauroneis Sp., Micraclinium Sp., Chrysymenia Sp., Micractinhnn Sp., Monaraphidium Sp., Nannochloris Sp., Navicida Sp., Porphyridium Sp., Nizymania Sp., Scenedesmus Sp., Synechoccus Sp. Navicul Sp., Nephrochloris Sp., Odontella Sp., Muriellopsis Sp., Tschia Sp., Nitzschia Sp., Isochrysis Sp., Phaedactylum Sp., Lyngbya Sp., Aphanizomenonflos Sp., Ochromonas Sp., Oocyst Sp., Bacillariophyceae Sp. ., Pamchlorelta Sp., Peyssonnelia Sp., Pascheria Sp., Pavlova Sp., Phaeodactyhan Sp., Cylindrospermum Sp., Tolypothrix Sp., Hapalosiphon Sp., Cylindrotheca Sp., Anacystis Sp., Ertilissima Sp., Aulosira Sp., Phortmdium Sp., Platytnonas Sp., Pleurochrysis Sp., Leptolyngbya Sp., Neochloris Sp., Prototheca Sp., Pseudochlorella Sp., Hormotilopsis Sp., Gyrodinium Sp., Ellipsoidion Sp., Pyramimonas Sp., Pyrobotrys Sp., Sarcinoid Sp. ., Aminariaceae Sp., Schizochytrmm Sp., Spirogyra Sp., Stichococcus Sp., Synechococcas Sp., Synechocystisf Sp., Tagetes Sp., Tetraedron Sp., Tetraselmis Sp., Thalassiosira Sp., Viridiella Sp., Alana Sp., Saccharina Sp., Coelarthrum Sp., Nereocystis Sp., Laminaria Sp., Porphyra Sp., Phaeocystis Sp., Aphanocapsa Sp., Phacelocarpus Sp., Ulva Sp., Himanthalia Sp., Cyanothece Sp., Ascophyllum Sp., Focus Sp., Carrarycus Sp., Betaphycus Sp., Gelidium Sp., Planktothricoides Sp., Prochlorococcus Sp., Prochloron Sp., Prochlorothrix Sp., Blastophysa Sp., Pedinomonas Sp., Resultor Sp. ., Marsupiomonas Sp., Chlorokybus Sp., Coleochaete Sp., Awadhiella Sp., Prymnesiophycees Sp., Radioramus Sp., Conochaete Sp., Chori stocarpaceae Sp., Lithothamnion Sp., Phymatolithion Sp., Discosporangiaceae Sp., Ishigeaceae Sp. , Petrodermataceae Sp., Syringodermataceae Sp., Portieria Sp., Onslowiaceae Sp., Dictyotaceae Sp., Lithodermataceae Sp., Eustigmatophyte Sp., Phaeostrophionaceae Sp., Amphidinum Sp., Sphacelodermaceae Sp., Micractinium Sp., Sargassum Sp., Curdiea Sp., Stypocaulaceae Sp., Coelothrix Sp., Cladostephaceae Sp., Sphacelariaceae Sp., Fucus Sp., Asterocladaceae Sp., Lessoniaceae Sp., Ascoseiraceae Sp., Cutleriaceae Sp., Eklonia Sp., Arthrocladiaceae Sp., Desmarestiaceae Sp. , Acinetosporaceae Sp., Adenocystaceae Sp., Chlamydomonas Sp., Cladophora Sp., Prasi nophyceae Sp., Chordariaceae Sp., Chordariopsidaceae Sp., Gelidiopsis Sp., Agmenellum Sp., Desmodesmus Sp., Ectocarpaceae Sp., Mesosporaceae Sp., Halydris Sp., Myrionemataceae Sp., Pylaiellaceae Sp., Bifurcariopsidaceae Sp., Chlorococcum Sp. ., Durvillaeaceae Sp., Fucaceae Sp., Glossomastix Sp., Himanthaliaceae Sp., Iridaea Sp., Hormosiraceae Sp., Notheiaceae Sp.,

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Sargassaceae Sp., Acrosiphonia Sp., Seirococcaceae Sp., Goniochloris Sp., Gloeothece Sp., Emiliana Sp., Codium Sp., Akkesiphycaceae Sp., Alariaceae Sp., Monochrysis Sp., Palma Sp., Chordaceae Sp., Acetabularia Sp. ., Phaffia Sp., Costariaceae Sp., Platymonia Sp., Pseudochordaceae Sp., Nemodermataceae Sp., Neoralfsiaceae Sp., Mphora Sp., Rhodymenia Sp., Ralfsiaceae Sp., Analipus Sp., Chnoosporaceae Sp., Egregia Sp., Scytosiphonaceae Sp., Chaetomorph Sp., Scytothamnaceae Sp., Gymnogongrus Sp., Asperococcus Sp., Bryopsis Sp., Rhizoclonium Sp., Gloiocladia Sp., Ecklonia Sp, Girgatina Sp., Hymenocladia Sp., Lomentaria Sp., Schizochytrium Sp. , Aphanotece Sp., Splachnidiaceae Sp., Sporochnaceae Sp., Plocamium Sp., Constantinea Sp., Cryptosiphonia Sp., Webervanboas sea Sp., Lessoniopsis Sp., Chondracanthus Sp., Halosiphonaceae Sp., Dictyopteris Sp., Farlowia Sp., Anadyomene Sp., Apelvetia Sp., Endocladia Sp., Heterokontophyta Sp., Coralline Sp., Thraustochytrium Sp., Osmundea Sp., Callophyllis S p.M Calliarthron Sp., Monoraphidium Sp., Penicillus Sp., Meristotheca Sp., Wrack Sp., Cosmocladium Sp., Calothrix Sp., Polysiphonia Sp., Prionitis Sp., Leathesia Sp., Polyneura Sp., Pelvetiopsis Sp., Chlamidonomas Sp., Neorhodomela Sp., Microdictyon Sp., Masonophycaceae Sp., Melobesia Sp., Dinoflagellate Sp., Delesseria Sp., Phyllariaceae Sp., Postelsia Sp., Microcladia Sp., Stschapoviaceae Sp., Dilsea Sp., Halimeda Sp. , Chroococus Sp., Tilopteridaceae Sp., Phaeodactylum Sp., Semnocarpoa Sp., Champia Sp., Erythrophyllum Sp., Chodium Sp., Paonia Sp., Ulothrix Sp., Heterochordariaceae Sp., Gracilaria Sp., Rivularia Sp., Phromidium Sp., Stypopodium Sp., Erythrocladia Sp., Bracchiomonas Sp., Coradophylum Sp., Cyanophyta Sp., Dysmorphococcus Sp., Cystoseira Sp., Dilophus Sp., Gloiotrichus Sp., Liagora Sp., Eisenia Sp., Ganonema Sp. , Hennedya Sp., Codiophyllum Sp., Ecklonia Sp., Distromium Sp., Sparlingia Sp., Gastrocelonium Sp., Claviclonium Sp., Pelvetia Sp., Mazzaella Sp., Lobophora Sp., Pterocladia Sp., Scinaia Sp., Galaxaura Sp., Gloiopeltis Sp., Scillatoria Sp., Hypnea Sp., Hormophysa Sp., Dotyophycus Sp., Opuntiella Sp., Nannochloropsis. Sp., Myriodesma Sp., Tricleocarpa Sp., Trichogloea Sp., Yamadaella Sp., Sebdenia Sp., Gelinaria Sp., Prymnesium Sp., Herposiphonia Sp., Jeannerettia Sp., Kuetzingia Sp., Laurencia Sp., Lenormandiopsis Sp. , Halymenia Sp., Eucheuma Sp., Erythroclonium Sp., Achnanthes Sp., Rhodopeltis Sp., Dudresnaya Sp., Halosaccion Sp., Zonaria Sp., Areschougia Sp., Hincksia Sp., Osmundaria Sp., Placophora Sp., Lophocladia Sp., Macrocystis Sp., Callophycus Sp., Microcoleus Sp., Epiphloea Sp., Acrosymphyton Sp., Cryptonemia Sp., Enteromorpha Sp., Neurymenia Sp., Lophosiphonia Sp., Microcystis Sp., Protokuetzingia Sp., Leveillea Sp. , Caulocystis So., Hydroclathrus Sp., Scaberia Sp., Rosenvingea Sp., Schizothrix Sp., Rhodella Sp., Spirocladia Sp., Acrochaetium Robustum Borgesen, Tolypiocladia Sp.,

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Tylotus Sp., Dicranema Sp., Pachydictyon Sp., Austronereia Sp., Sporochnus Sp., Craspedocarpus Sp., Solieria Sp., Encyothalia Sp., Nanococcus Sp., Gracilaria Sp., Grateloupia Sp., Hildenbrandiasp., Amphiroa Sp. , Cheilosporum Sp., Corallina Sp., Hydrolithonsp., Hydrolithonsp., Jania Sp., Lithophyllumsp., Catenella Sp., Chondracanthus Sp., Hypnea Flagelliformissp., Ahnfeltiopsis Sp., Champia Sp., Gastroclonium Sp., Gelidiopsis Sp., Gayliellaflaccidasp., Aglaothamnion Sp., Crouania Sp., Ptilothamnion Sp., Dasya Sp., Caloglossa Sp., Aloglossa Sp., Erythroglossum Sp., Martensia Fragilissp., Bostrychia Sp., Chondria Sp., Herposiphonia Sp., Laurencia Obtusesp. , Neosiphonia Sp., Polysiphonia Sp., Vaucheria Sp., Feldmanniasp., Hinksia Sp., Ralfsiasp., Sphacelaria Sp., Canistrocarpus Sp., Dictyota Sp., Padina Sp., Spatoglossum Sp., Spatoglossum Sp., Stoechospermum Sp. , Chnoospora Sp., lyengaria Sp., Gayralia Sp., Chaetomorpha Sp., Cladophora Sp., Cladophoroposis Sp., Phyllodictyon Sp., Valoniopsis S p., Bryopis Sp., Caulerpa Sp., Avrainvillea Sp., Chlorodesmis Sp., or derivatives and mixtures thereof. However, those skilled in the art will appreciate the ability to use any other genera of algae known in the art without departing from the scope of the invention. These algae are commercially grown and marketed by various companies.

According to another embodiment of the invention, these algae may be at least one of the following species, without being limited to:

Anabena cylindrical, Bryopsis australis, Bryopsis minor, Botryococcus braunii, Actmanthes orientalis, Amphiprora hyaline, Amphora coffeiformis, Petrocelis Sp., Amphora cqffeifoiinis Var. Linea, Chlorideila simplex, Apelvetia canaliculata, Caulerpa taxifolia, Amphora Cqffeiformis Var. Punctata, Amphora Cqffeiformis var. Taylori Ulva Paschima Bast Cladophora Goensis Bast Laurencia spectabilis Gymnogongrus crenulatus Opuntiella californica Gymnogongrus griffithsiae Achnanthes orientalis Cladosiphon filum Goniochloris sculpta Ecklonia cava Osmundea Spectabilis Neorhodomela Larix Cliftonii, Caulerpa Cupressoides, Caulerpa Fergusonii, Caulerpa Lentillifera, Caulerpa Mexicana, Ahnfeltia Plicata, Caulerpa Obscura, Caulerpa Racemosa, Caulerpa Racemosa Var. Corynephora, Caulerpa racemosa var. Laetivirens, Caulerpa racemosa var. Lamourouxii, Caulerpa racemosa var. Peltata, Caulerpa Serrulata, Caulerpa Simpliciuscula, Asteromenia Peltata, Botryocladia Skottsbergii, Ceratodictyon Spongiosum, Chrysymenia Kaernbachii, Chrysymenia Ornata, Coelarthrum Cliftonii, Coelothrix Irregularis, Gelidiopsis Variabilis,

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Gloiocladia Halymenioides, Pterocladia Capillacea, Prymnesium Parvum, Gloiocladia Indica, Gloiocladia Rubrispora, Gloiosaccion Brownii, Gelidium Pusilium, Hymenocladia Usnea, Phymatolithion Calcereum, Lithothamnion Calcareoum, Herposiphonia Secunda, Herposiphonia Secunda F. Tenella, Heterostromanere Reidiis, Jeanetaliculettia Kuzingia , Laurencia Brongniartia, Laurencia Cruciata, Laurencia Filiformis, Laurencia Majuscula, Laurencia Papillosa, Lenormandiopsis Latifolia, Leveillea Jungermannioides, Lophocladia Harveyi, Lophosiphonia Prostrata, Neurymenia Fraxinifolia, Osmundaria Spiralis, Placophora Binderi, Polysiphonia Decipiens, Polysiphonia Gracilis, Protokuetsisocladia, Spirioclaly Glomerulata, Amphiroa Anceps, Amphiroa Foliacea, Amphiroa Gracilis, Haliptilon Roseum, Hydrolithon Farinosum, Hydrolithon Onkodes, Jania Pulchella, Lithophyllum Bermudense, Mesophyllum Engelhartii, Mesophyllum Erubescens, Mesophyll um Funafutiense, Metagoniolithon Radiatum, Metagoniolithon Stelliferum, Metamastophora Flabellata, Pneophyllum Fragile, Gelidium Austral, Pterocladia Lucida, Gelidiella Pannosa, Amphiplexia Hymenocladioides, Claviclonium Ovatum, Hennedya Crispa, Areschougia Ligulata, Callophycus Serratus, Callophycus Oppositifolius, Eucheiclonumaticum Gelidium, , Eucheuma Speciosum, Meristotheca Papulosa, Solieria Robusta, Craspedocarpus Venosus, Dicranema Revolutum, Tylotus Obtusatus, Acrosymphyton Taylorii, Dudresnaya Capricornica, Rhodopeltis Borealis, Hypnea Spinella, Hypnea Valentiae, Stylonema Alsidii, Audouinella Saviana, Asparagopsis Armata, Asis, Asisglaothamnii Taxiionis Cordatum, Anotrichium Tenue, Antithamnion Antiillanum, Antithamnion Armatum, Antithamnion Hanovioides, Carpothamnion Gunnianum, Centroceras Clavulatum, Ceramium Filicula, Ceramium Flaccidum, Ceramium Isogonum, Ceramium Macilentum, Ceramium Mazatlanense, Ceramium Pu berulum Ceramium Sherpherdii Ceramium Sympodiale Spyridia Filamentosa, Tanakaella Itonoi, Trithamnion Gracilissimum, Wrangelia Plumosa, Dasya lyengarii, Dasya Pilosa, Acrosorium Decumbens, Claudea Elegans, Cottoniella Filamentosa, Haraldiophyllum Erosum, Hemineura Frondosa, Heterodoxia Denticulata, Hypoglossum Caloglossoides, Hypoglossum Revolutum, Martensia Australis, Martensia Fragilis, Platysiphonia Corymbosa , Platysiphonia Delicata, Platysiphonia Marginalis, Sarcomenia Delesserioides, Acanthophora Dendroides, Acanthophora Spicifera, Chondria Curdieana, Chondria Dangeardii, Chondria

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Lanceolata, Dasyclonium Flaccidum, Dasyclonium Incisum, Dictyomenia Sonderi, Dictyomenia Tridens, Ditria Expleta, Doxodasya Bolbochaete, Endosiphonia Spinuligera, Rhodymenia Leptophylla, Rhodymenia Sonderi, Webervanboassea Splachnoides, Glaphrymenia Pustulosa, Kallymenia Cribrogloea, Kallymenia Cribrosa, Nemastoma Damaecornis, Predaea Laciniosa, Predaea Weldii, Titanophora Weberae, Nizymania Conferta, Peyssonnelia Capensis, Peyssonnelia Inamoena, Phacelocarpus Alatus, Portieria Homemannii, Curdiea Obesa, Gracilaria Canaliculata, Gracilaria Preissiana, Gracilaria Textorii, Codiophyllum Flabelliforme, Erythrocladia Irregularis, Cryptonemia Kallymeniodenides, Epiphloea Bullosa, Gelinaria Ulvoidea, Halyb , Porphyra Crispate Kjellman, Gracilaria Corticata, Gracilaria Foliifera, Gracilaria Verrucosa, Grateloupia Filicina, Grateloupia Filicina F. Horrida, Grateloupia Lithophila, Peyssonnelia Obscura, Hildenbrandia Rubra, Amphiroa Anceps, Amphiroa Fragilissima, Am phiroa Rigida Cheilosporum Spectabile Corallina Officinalis Hydrolithon Farinosum Hydrolithon Reinboldii Jania Rubens Lithophyllum Orbiculatum Catenella Caespitose Chondracanthus Acicularis Hypnea Flagelliformis Hypnea Musciformis Hypnea Spinella Hypnea Valentiae Ahnfeltiopsis Pygmaea Compressium Champia , Gelidiopsis Variabilis, Antithamnion Cruciatum, Ceramium Cimbricum, Ceramium Cruciatum, Gayliellaflaccida, Aglaothamnion Tenuissimum, Crouania Attenuata, Ptilothamnion Speluncarum, Wrangelia Argus, Dasya Ocellata, Caloglossa Leprieurii, Aloglossa Ogasawaraensis, Erythroglossum Lusitanicum, Hypoglossum Hypoglossoides, Acanthophora Muscoides, Bostrychia Radicans, Bostrychia Tenella , Chondria Armata, Chondria Capillaries, Herposiphonia Secunda, Laurencia Obtuse, Neosiphonia Ferulacea, Polysiphonia Atlantica, Polysiphonia Denudate, Vaucheria Longicaulis, Feldmannia Indica, Feldmannia Irregularis, Hinksia Mitchelliae, Ralfsia Verrucosa , Sphacelaria Rigidula, Canistrocarpus Cervicomis, Canistrocarpus Crispatus, Canistrocarpus Magneanus, Dictyopteris Australis, Dictyota Bartayresiana, Dictyota Ceylanica, Dictyota Ciliolate, Dictyota Dichotoma, Dictyota Divaricata, Dictyota Dumosa, Padina Antillarum, Padina Australis, Padina Boryana, Padina Gymnospora, Padina Pavonica, Spatoglossum Asperum, Spatoglossum Variabile, Stoechospermum Polypodioides, Chnoospora Minima, Colpomenia Sinuosa, lyengaria Stellata, Rosenvingea Orientalis, Sargassum Cinctum, Sargassum Cinereum, Sargassum Crassifolium, Sargassum Glaucescens, Sargassum Ilicifolium, Sargassum Plagiophyllum, Sargassum Polycystum, Sarsumer, Tengassum Prismaticum, Sargassum Vulgare, Gayralia Oxysperma, Ulva Clathrata, Ulva Compressa, Ulva Conglobata, Ulva Flexuosa, Ulva

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Intestinalis Ulva Rigida Ulva Taeniata Chaetomorpha Antennina Chaetomorpha Linum Composite, Cladophoroposis Sundanensis, Phyllodictyon Anastomosans, Valoniopsis Pachynema, Bryopis Hypnoides, Bryopsis Pennata, Bryopsis Plumose, Caulerpa Peltata, Caulerpa Racemosa, Caulerpa Scalpelliformis, Caulerpa Sertularioides, Caulerpa Verticillata, Avrainvillea Erecta, Chlorodesmis Hildebrandtii, Dotyophycus Abbottiae, Ganonema Farinosa, Gloiotrichus Fractalis, Liagora Setchellii, Trichogloea Requienii, Yamadaella, Galaxaura Marginata, Galaxaura Obtusata, Galaxaura Rugosa, Scinaia Tsinglanensis, Tricleocarpa Cylindrica, Plocamium Preissianum, Champia Compressa, Champia Pravula, Champia Zostericola, Lomentaria Cor allicola, Lomentaria Monochlamydea, Semnocarpoa Minuta, Caulerpa Webbiana, Caulerpa Racemosa Var. Turbinata Neorhodomela Oregona, Odonthalia Floccose, Odonthalia Floccosa Forma Comosa, Odonthalia Washingtoniensis, Ecklonia Kurome, Mastocarpus Jardinii, Acetabularia Calyculus, Halimeda Cuneata, Padina Sp. , Ecklonia Stoloifera, Microcladia Borealis, Microdictyon Umbilicatum, Ecklonia Maxima, Ecklonia Radiate, Nereocystis Luetkeana, Penicillus Nodulosus, Ecklonia Bicyclis And Ecklonia Arborea, Eisenia Bicyclis, Eisenia Arboraea, Halosaccion Glandiforme, Amphora Coffeiformis Var. Tenuis, Dictyosphaeria Cavernosa, Dictyopteris Muelleri, Dictyopteris Plagiogramma, Dictyota Ciliolata, Dictyota Dichotoma, Dictyota Dichotoma Var Intricata, Dictyota Furcellata, Dictyota Mertensii, Dictyota Naevosa,Dilophus Crinitus, Dilophus Fastigiatus, Dilophus Robuschy, Distromium Flabellatum, Pandictbosumum Flabellatum, Pandictbosumum Boryi, Sargassum Decurrens, Sargassum Distichum, Sargassum Fallax, Sargassum Ligulatum, Sargassum Linearifolium, Sargassum Podacanthum, Sargassum Spinuligerum, Sargassum Tristichum, Padina Boergesenii, Padina Elegans, Padina Sanctae-Crucis, Padina Tenuis, Stypopodium Australasicum, Stypopodium Flabelliforme, Zonariack Tumeriana Mitchelliae, Caulocystis Uvifera, Cystoseira Trinodis, Hormophysa Cuneiformis, Myriodesma Quercifolium, Scaberia Agardhii, Ecklonia Radiata, Hydroclathrus Clathratus, Sphacelaria Biradiata, Sphacelaria Novae-Hollandiae, Sphacelaria Rigidula, Austronereia Australis, Encyothalia Cliftonii, Sporochnus Comos us, Dictyosphaeria Versluysii, Amphora Delicatissima, Amphora Delicatissima Var. Capitata, Cosmocladium Perissum, Anabaena, Anadyomene Brownie, Anftistrodesmus,

- 14 040318

Ammsirodesnms Falcatus, Dilsea Californica, Gigartina Agardhii, Delesseria Decipiens, Polyneura Latissima, Mastocarpus Papillatus, Cryptosiphonia Woodii, Porphyra Pseudolanceolata, Melobesia Mediocris, Boekelovia Hooglandii, Codium Duthieae, Codium Geppiorum, Codium Laminarioides, Codium Lucasii, Codium Spongiosum Plocamisium, Hypnea Musciformis, Meristotheca Senegalensis, Sparlingia Pertussa, Meristotheca Papulosa, Halydris Siliquosa, Rhodymenia Pertussa, Botryococcus Brmmii, Botryococcus Sudeticus, Erythrophyllum Delesserioides, Gigartina Papillata, Bracteococcus Minor, Egregia Menziesii, Laminaria Sinclairii, Bracteococcus Medionucleats, Lessoniopsis Littoralis, Carteria, Chaetoceros Gracilis, Ectocarpus Sp., Valonia Macrophysa, Gloiopeltis Furcata, Bossiella Sp., Constantinea Simplex, Colpomenia Bullosa, Ahnfeltiopsis Linearis, Colpomenia Peregrine, Endocladia Muricata, Callithamnion Pikeanum, Choetoceros Muejleri, Calliarthron Tuberculosum, Choetoceros Mueeri Var. Subsalsum, Chlamydomas Perigratmlata, Chlorella Anitrata, Chlorella Antarctica, Chloreuaureoviridis, Chlamydomonas Rheinhardii, Neochloris Oleoabundans, Emiliana Huxleyi, Chlamydomonas Sajao, Gigartina Exasperate, Chondracanthus Exasperates, Chlamydomonas Moewusii, Candida, Chlorella Capsulate, Nanococcus Vulgaris, Pelvetiopsis Limitata, Chlorella Desiccate, Chlorella Ellipsoidea , Postelsia Palmaeformis, Chlorelia Etmrsonii, Sargassum Muticum, Chlorell Fusco, Eklonia Maxima, Chlorella Fusca Var. Vacuolate, Ceramium Rubrum, Chlorella Glucolropha, Leathesia Marina, Chlorella Infrisionum, Analipus Japonicas, Chlorella Infimon M Var. Actophija, Desmodesmus Asymmetricus, Chlorella Infustomtm Var. Attxenophila, Chlorella Kessleri, Chlorella Lobaphord, Chlorella Luieoviridis, Chlorella Luieoviridis Var. Aureovmdts, Ralfsia Fungiformis, Ceramium Codicola, Chlorella Hiteavmdis Var, Hitescens, Chlorella Riniata, Chlorella Minttssima, Chlorella Mutabilis, Chlorella Nocturna, Chlorella Ovalis, Costaria Costata, Desmarestia Ligulata, Fucus Vesiculosus, Fucus Serratus, Chlorella Parva, Chlorella Pyrenoidosa, Chlorella Phoiidosa, Chlorella Pringsheimii, Chlorella Protothecoides, Chlorella Protat Ecoides Var. Acidicola, Chlorella Regularis, Prionitis Sternbergii, Chlorella Regularis Var. Minima, Chlorella Regularis var. Umbricata, Chlorella Reisiglii, Chlorella Saecharophila, Chlorella Saecharophila Var. Ellipsoidea, Chlorella Salina, Chlorella Simplex, Chlorell Sorokmiana, Chlorella Sphaerica, Chlorella Stigmatophora, Chlorella Varlellii, Chlorella Vulgaris, Codium Setchellii, Corallina Vancouveriensis, Chlorella Vulgaris Fo. Tertia, Chlorella Vulgaris var. Autotroph lea, Chlorella Vulgaris var. Viridis, Chlorella Vulgaris var. Vulgaris, Chlorella Vulgaris Var Vulgaris Fo. Tertia, Chlorella Vulgaris var. Vulgaris Fo. Viridis, Chlorella Xamhella, Chlorella Zofingiensis, Chlorella Irebouxioides, Chlorococcum Infusiovum, Chlorogoni N, Crypthecodinium Cohnii,

- 15 040318

Cyclotella Cryptica, Cyclotejla Meneghiniana, Dimaliella Hardawil, Dunaliella Bioculata, Dimaliella Granulate, Dunaliella Maritime, Dunaliella Minuta, Dimaliella Parva, Dunaliella Peircei, Dunaliella Primolecta, Bossiella Plumose, Dunaliella Salina, Dimaliella Terricoia, Dunaliella Tertiolecta, Dunaliella Viridis, Dunaliella Tertioiecta Virid, Erisemosemos , Euglena Gracilis, Franceia Sp., Fragilari Crotonensis, Haematococcus Pluvialis, Bockrysis Off. Galbana, Hochrysis Galbana, Lepocinclis, Micraclinium, Micractinhnn, Monaraphidium Mh T M, Nannochloropsis Salina, Navicida Accepiata, N Vicula Biskanterae, Navicula Pseudotenelloides, Porphyridium Cruentum, Porphyridium Parvum, Scenedesmus Dimorphus, Navicul Pellicidosa, Navicida Saprophtla, Tschita, Odontella Aurschia Alexandrine Nitzschia Clostenum Nitzschia Communis Monoensis, Palmaria Mollis, Rhodymenia Palmata F. Mollis, Nitzschia Quadrangular, Oocystis Pusilia, Oscillatoria Limnetica, Acrosiphonia Coalita, Oscillatoria Subbrevis, Pamchlorelta Kessleri, Pascheria Acidophila, Phaeodactyhan Tricomutwn, Tolypothrix Tenuis, Hapalosiphon Fontinalis, Ertilissimaphag us. Phortmdium, Pleurochrysis Camerae, Pleurochrysis Dentate, Pleurochrysis Carterae, Prototheca Wickerhamii, Prototheca Stagnora, Prototheca Ponoricensis, Prototheca Moriformis, Prototheca Zopfii, Pseudochlorella Aquatica, Pyrobotrys, Rhodococcus Opaciis, Sarcinoid Chrysophyte, Scenedesmus Annatus, Scenedesmus Obliquus, Scenedesmus Quadricauda, Schizochytrmm, Spirulina Platensis , Spirulina Maxima, Synechocystisf, Tagetes Erecta, Tagetes Pat La, Tetraedron, Tetrasehnis Suecica, Codium Fragile, Thalassiosira Weissflogii, Viridiella Fridericiana, Palmaria Palmate, Alaria Esculenta, Saccharina Latissima, Saccharina Sessilis, Saccharina Dentigera, Laminaria Saccharina, Porphyra Umatabilicalis , Ulva Lactuca, Ulva Armoricana, Laminaria Digitata, Himanthalia Elongata, Ascophyllum Nodosum, Laminaria Longicruris, Scytosiphon Dotyi, Scytosiphon Lomentaria, Porphyra Yezoensis, Focus Vesiculosus, Kappaphycus Alvarezii, Betaphycus Gracilaria, Gelidium Pterocladia, Soranthera Ulvoidea, Ch ondrus Crispus, Mastocarpus Stellatus, Gracilaria Edulis, Lithiothamne, Phaeostrophion Irregulare, Enteromorpha Intestinalis, Enteromorpha Compressa, Psedoanabeana NIVA CYA 3, Nostoc Sp. MASS 661, Macrocystis Pyrifera, Asparagopsis Armata, Mazzaella Flaccida Iridaea Flaccid, Mazzaella Oregona, Iridaea Oregona, Iridaea Heterocarpa, Mazzaella Parksii, Iridaea Comucopiae, Mazzaella Splendens, Iridaea Cordata, Or Marl or derivatives or mixtures thereof. However, those skilled in the art will appreciate the possibility of using any other species known in the art without departing from the scope of the invention. These algae are commercially grown and marketed by various companies.

According to another embodiment of the invention, these may be algae of the species Spirulina, Arthrospira, Chlorella, Anabaena, Scenedesmus, Aphanizomenon, Dunaliella, Phymatolithion, Lithothamnium, Ascophyllum or their derivatives, species and mixtures. According to another embodiment of the invention, these may be algae of the species Spirulina Plantensis, Spirulina Maxima, Anabaena Cylindrica, Scenedesmus Obliquus, Ascophyllum Nodosum, Phymatolithion calcereum, Lithothamnium calcereum, Aphanizomenon Flos-Aquae, Dunaliella Salina or their derivatives, species and mixtures. However, those skilled in the art will appreciate the ability to use any other species of Spirulina, Arthrospira, Anabaena, Scenedesmus, Ascophyllum, Aphanizomenon, Dunaliella, Phymatolithion, Lithothamnium or other algae known in the art without departing from the scope of the invention. These algae are grown in industrial

- 16 040318 scale and implemented by various companies.

According to an embodiment of the invention, the algae are present in a concentration range of at least 0.1%. According to another embodiment of the invention, algae are present in a concentration range of at least 1% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 5% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 10% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 20% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 30% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 40% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 50% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 60% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 70% of the total weight of the composition. According to another embodiment of the invention, algae are present in a concentration range of at least 80% of the total weight of the composition. According to another embodiment of the invention, the algae are present in a concentration range of at least 90% of the total weight of the composition. According to another embodiment of the invention, the composition contains at least 95% by weight of algae.

The invention also relates to a water-disintegrating granular composition for agricultural use containing at least one pesticidal active and at least one agrochemically acceptable excipient. The water-disintegrating granules containing the pesticidal active have a size of 0.1 to 6 mm and include particles in the size of 0.1 to 50 µm.

According to another embodiment, the granules of the water-disintegrating composition for agricultural use are 0.1 to 6 mm in size. According to another embodiment, the granules of the composition for agricultural use have a size of 0.5 to 6 mm. According to another embodiment, the granules of the composition for agricultural use have a size of 1 to 6 mm. According to another embodiment of the invention, the granules for agricultural use are 1 to 5 mm in size. According to another embodiment of the invention, the granules for agricultural use are 2.5 to 5 mm in size.

According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 100 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.1 to 80 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 50 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 50 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 40 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 30 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 20 microns. According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 15 microns.

According to an embodiment of the invention, the granules contain particles ranging in size from 0.2 to 10 microns.

According to another embodiment, the pesticidal active substance contains at least one of the group of compounds: antifoulants, attractants, insecticides, fungicides, herbicides, nematocides, pheromones, defoliants, acaricides, plant growth regulators, algicides, antifeedants, avicides, bactericides, bird repellents , iopesticides, biocides, chemosterilizers, plant protection products, insect attractants, insect repellents, insect growth regulators, mammal repellents, male depressants, desiccants, disinfectants, molluscicides, antimicrobial agents, miticides, ovicides, fumigants, plant activators , rodenticides, synergists, virucides, repellents, microbial pesticides, incorporated plant protectants or salts, derivatives and mixtures thereof.

According to another embodiment, the pesticidal actives include, but are not limited to, at least one of the following: abamectin, abamectinaminomethyl, abscisic acid, ACC, acephate, acetamiprid, acetion, acetochlor, acetophenate, acetophos, acetoprol, acibenzolar, acifluorophen, aclonifen , ACN, acrepe, acrinathrine, acrylonitrile, acinonapir, acipetax, afidopyropene, afoxolaner, alanap, alanicarb, albendazole, aldicarb, aldicarb sulfone, aldimorph, aldoxycarb, aldrin, allethrin, d-trans-allethrin, allicin, alidochlor, aloximidine, aloximidine allyl alcohol, alixicarb, allorac, alpha-bromadiolone, alpha-cypermethrin, alphaendosulfan, alphamethrin, altretamine, aluminum phosphide, amethoctradine, ametridine, ametrine, amibusine, amicarbazone, amicarthiazole, amidithione, amidochlor, amidoflumet, amidosulfuron, aminocarb, aminocyclopyrad, 4-aminopyridine, aminotriazole, amiprofos-methyl, amiprofos, amiprofos-methyl, amisulbrom, amiton, amitrol, ammon sulfamate ia, amobam, amorphous silica gel, amorphous silicon dioxide, ampropylphos, AMS, anabasine, ancimidol, anilazine, anilofos, anisuron,

- 17 040318 anthraquinone, antu, afolate, aramit, arprocarb, arsenic oxide, asomat, aspirin, asulam, atidation, atraton, atrazine, aureo-fungin, avermectin, AVG, aviglycine, azaconazole, azadirachtin, azaphenidine, azamethythion, azamethifos azinfosetil, azinfosetil, azinphos-methyl, azinphosmethyl, aziprothrin, azithiram, azobenzene, azocyclotin, nitrogenate, azoxystrobin, bahmedesh, barbanate, barium hexafluorosilicate, barium polysulfide, barium silicofluoride, batrine, basic copper carbonate, basic copper chloride, basic copper sulfate, BCPC , beflubutamide, benalaxyl, benalaxyl-M, benazoline, bencarbazone, benclothiaz, fenridazone-propyl, bendiocarb, bendioxide, benefin, benfluralin, benfuresate, benodanil, benoxacor, benoxafos, benquinox, bensulfuron, bensulide, bentaluron, benthibentibentavalicarb, , Benthranil, Benzadox, Benzalkonium Chloride, Benzamacryl, Benzamisole, Benzamorph, Benzene Hexachloride, Benzfendison, Benzimine, Benzipram, Benzobicyclone, Benzoepine, Benzofenap, Benzophoro , benzhydroxamic acid, benzomate, benzophosphate, benzothiadiazol, benzovindiflupyr, benzoximate, benzoylprop, benzpyromoxane, benzthiazuron, benzyl adenine, benzyl benzoate, berberine, betacyfluthrin, beta-cypermethrin, betoxazine, HCB, gamma-HCB, bialafos, bicyclopyrone, cappa-phenox, bifenthrin bifenthrin, bifuyunzi, bilanaphos, binapacryl, bingquingxiao, bioallethrin, Sbioalletrin, bioetanometrin, biopermethrin, bioresmethrin, biphenyl, bisazir, bismertiazole, bismertiazole-copper, bisphenyl-mercury methylenedi (x-naphthalene-y-sulfonate), bispyribac, bistrifluron, bisultap, bitertanol, bitionol, bixaphene, plasticidin-S, borax, bordeaux liquid, boric acid, boscalid, BPCMS, BPPS, brasinolide, brasinolide-ethyl, brevicomin, brodifacoum, brofenprox, brofenvalerate, broflanilid, brofluthrinate, bromacil, bromadiolone, alpha-bromadiolone, Bromochlorvos, Brometalin, Bromethrin, Bromfenvinphos, Bromoacetamide, Bromobonyl, Bromobutide, Bromocyclene, Bromo-DDT, Bromophenoxime, Bromophos, Bromomethane, Bromophos-Ethyl, Bromopropyl at, bromothalonil, bromoxynil, bromopyrazone, bromuconazole, bronopol, BRP, VTH, bucarpolate, bufencarb, buminafos, bupirimate, buprofezin, Burgundy mix, busulfan, butacarb, butachlor, butafenacil, butam, butamiphos, butanfipronil, butathiophos, butenachlor, butene-fipronil , butetrin, butidazole, butiobate, butiuron, butifos, butocarboxym, butonate, butopyronoxyl, butoxycarboxym, butralin, butrizol, butroxydim, buturon, butylamine, butylate, butylchlorophos, butylene fipronil, cacodylic acid, cadusafos, cafenstrol, calciferol, calcium arsenate, chlorate calcium, calcium cyanamide, calcium cyanide, calcium polysulfide, calvinphos, cambendichlor, camphechlor, camphor, d-camphor, captafol, carbam, carbamorph, carbanolate, carbaryl, carbasulam, carbathion, carbendazim, carbendazole, carbetamide, carbophenotion, carbofuran, carbon disulfide, carbon tetrachloride, carbonyl sulfide, carbophenotion, carbophos, carboxazole, carboxide, carboxine, carfentrazone, carpropamide, carvacrol, carvone, CAVP, CDAA (αchlorine -K,K-dialylacetamide), CDEA (a-chloro-K,K-dialylacetanide), CDEC, celocidin, SEPC, ceralur, cerenox, tsevadil, Cheshant mixture, quinalphos, quinalphos-methyl, chiralaxil, chitosan, chlobentiazone, chloromethoxifene, chlor-IFK, chloralose, chloramben, phosphorus chloramine, chloramphenicol, chloraniformmethane, chloranil, chloranocryl, chlorantraniliprole, chlorazifop, chlorazine, chlorobenzide, chlorbenzuron, chlorbicyclene, chlorbromuron, chlorbufam, chlordan, chlordecone, chlordimeform, chlorempentra, chlorethoxyphene, chlorethoxyphenate , хлорфенак, хлорфенапир, хлорфеназол, хлорфенетол, хлорфенидим, хлорфенпроп, хлорфензон, хлорфенсульфид, хлорфенвинфос, хлорфенвинфос-метил, хлорфлуазурон, хлорфлуразол, хлорфлурекол, хлорфлурен, хлорфлуренол, хлоридазон, хлоримурон, хлоринат, хлормефос, хлормекват, хлормесулон, хлорметоксинил, хлорнидин, хлорнитрофен , chloroacetic acid, chlorbenzilate, chlordinitronafthalenes, chlorphenisone, chloroform, α-chlorohydrin, chlormebuform, chloromethiuron, chloroneb, chlorofacinone, chlorophos, chlorophtha LM, Chloropicrin, Chloropon, Chloropraletrin, Chloropropylate, Chlorothalonil, Chlorotoluron, Chloroxyphenidim, Chloroxuron, Chloroxynil, Chlorfonium, Chlorphoxim, Chlorophthalmos, Chlorprazophos, Chlorprocarb, Chloropram, Chlorpyrifos, Chlorpyrifos-methyl, Chlorquinox, Chlorsulfuron, Chlorophthal, chlorzolinate, chitosan, cholecalciferol, choline chloride, cromafenoside, cycloheximide, cymectacarb, cinerin I, cinerin II, cinerins, cinmethylin, cinosulfuron, cintophene, cyobutide, cisanilide, cismetrin, claciphos, clefoxidim, clenpyrine, clethodim, climbazole, clofetocarodinate, clofenotan, clofenvinphos, clofibric acid, clofop, clomazone, clomeprop, clonitralide, cloprop, cloprokisdim, clopiralide, cloquintoset, cloransulam, closantel, clothianidin, clotrimazole, cloxifonac, cloxilacon, closilacone, CMA, CMMP, CMP, CMU, colatecalciferolur , copper acetate, Scheinfurt greens, copper arsenate, basic copper carbonate, copper hydroxide, copper naphthenate, copper oleate, ok copper chloride, copper 8-quinolinolate, copper silicate, copper sulfate, basic copper sulfate, copper zinc chromate, cumahlor, cumafen, cumafos, cumafuryl, cumatetralyl, cumethoxystrobin, cumitoate, cumoxystrobin, 4-CPA, 4-CPB, CPMC, CPMF , 4-CPP, CPPC, credazine, cresol, cresylic acid, crimidine, crotamiton, crotoxyphos, crufomat, cryolite, cuelur, kufraneb, cumiluron, cuprobam, copper(I) oxide, curcumenol, CVMP, cyanamide, cyanathrine, cyanazine, cyanofenphos, cyanogens, cyanophos, cyanate, cyano-traniliprole, cyanuric acid, cyazofamide, cibutrin, ciclofuramide, cyclanilide, cyclaniliprole, cycletrin, cycloate, cycloheximide, cycloprate, cycloprothrin, cyclopyrimorate, cyclosulfamuron, cyclooxydim, cycluron, cyenopyraphene, cyfluphenamide, cyfluthrin, beta-cyfluthrin , cyhalodiamide, cyhalofop, cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin, cyhexitin, cimiazole,

- 18 040318 cyometrinil, cypendazole, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zetacypermethrin, cyperquat, cyfenotrin, cyprazine, ciprazole, cyproconazole, cyprodinil, cyprofuram, cypromide, cyprosulfamide, cyromazine, cythioate, 1,3 citrex D, 2,4-D, 3,4-DA, daimuron, dalapon, daminozide, deutong, 2,4-DB, 3,4-DB, DBCP, d-camphor, DCB, DCIP, DCPA (USA), DCPA (Japan), DCPTA, DCU, DDD, DDPP, DDT, pp'-DDT, DDVP, 2,4-DEB, debacarb, decafentine, decametrin, decarbofuran, N, N-diethyl-3-ethylbenzamide, dehydroacetic acid, diquat, delachlor, delnav, deltamethrin, demefion, demefion-O, demefion-S, demeton, demeton-methyl, demeton-O, demeton-O-methyl, demeton-S, demeton-S-methyl, demeton-S-methylsulfone, DEP, 2,4-DEP, depalethrin, derris root preparation, 2,4DES, desmedifam, desmetrin, d-fanshiluquebinjuzhi, diafenthiuron, dialyfor, dialyphos, dialat, dialat, diamidafos, dianat, diatomite, diazinon, dibrom, 1,2-dibromoethane , dibutyl phthalate, dibutyl succinate, dicamba, dicaptone, dichl obenil, dichlobentiazox, dichlofenthion, dichlofluanid, dichlon, dichloral-urea, dichlorobenzuron, dichlorphenidim, dichloroflurecol, dichloroflurenol, dichlormate, dichloromide, o-dichlorobenzene, ortho-dichlorobenzene, p-dichlorobenzene, para-dichlorobenzene, 1,2-dichloroethane, dichloromethane, dichlorophen, 3,6-dichloropicolinic acid, 1,2-dichloropropane, 1,3-dichloropropene, dichlorprop, dichlorprop-P, dichlozolin, diclobutrazol, diclocymet, diclofop, diclomesin, dicloran, dichlormesothiasis, diclosulam, dicofol, dicofan, dicoumarol, dicrezyl , Dicrotophos, Dicryl, Dicoumarol, Dicyclanil, Dicyclonone, Dieldrin, Dinochlor, Dietam-Quat, Dietatil, Dietion, Dietofencarb, Dietolate, Dietion, Dietylpyrocarbonate, Dietyltoluamide, Difenacum, Difenoconazole, Diphenopentene, Difenoxuron, Diphenzoquat, Difethialone, Difluvidazine, Diflufenican, Diflubenzuron , diflufenicanil, diflufenzopyr, diflumetorim, dikegulac, dilor, dimatif, dimefluthrin, dimefox, dimefuron, dimehypo, dimepiperate, dimethachlone, dimethane, dimetacarb, dimethachlone, dimethachlor, dimethame trine, dimethanamide, dimethanamide-P, dimethipine, dimethirimol, dimethoate, dimethomorph, dimethrin, dimethylcarbate, dimethyl disulfide, dimethyl phthalate, dimethylvinphos, dimethylan, dimexano, dimidazone, dimoxistrobin, dimpilate, dimuron, dinex, diniconazole, diniconazole-M, R-diniconazole, dinitramine, dinitrophenols, dinobuton, dinocap, dinocap-4, dinocap-6, dioctone, dinophenate, dinopentone, dinoprop, dinosam, dinoseb, dinosulfone, dinotefuran, dinoterb, dinoterbon, diofenolan, dioxabenzophos, dioxacarb, dioxathion, difacin, difacinone, diphenadione, difenamib, diphenamide, diphenylamine, diphenylsulfone, diphenylsulfide, diprogulic acid, dipropalin, dipropetrin, dipterex, dipimethitron, dipyrithione, diquat, disosultap, disparlur, disugran, disul, disulfiram, disulfoton, dithalymphos, diticrophos, dithioeter, dithiomethone, dithiopyr, diuron, dixanthogen , d-limonene, DMDS, DMPA, DNOC, dodemorph, dodicin, dodin, dofenapine, doguadin, dominicalur, doramectin, 2,4-DP, 3,4-DP, DPC, drazoxolone, DSMA, d-transalethrin, d-t ransresmetrin, dufulin, dimron, EBEP, EBP, ebufos, α-ecdysone, βecdysone, ecdysterone, echlomesol, EDB, EDC, EDDP, edifenphos, eglinazine, emamectin, EMPC, empentrin, enadenine, endosulfan, alpha-endosulfan, endothal, endothion, endrin, enestroburin, enilconazole, enoxastrobin, ethersulfonate, EPN, epocholeon, epofenonan, epoxiconazole, eprinomectin, epronase, epsilon-methofluthrin, epsilon-momfluotrin, EPTC, erbon, ergocalciferol, erlujixiancaoan, esdepalletrin, esfencelerate, ESP, etatocalasyl etafos, etem, ethaboxam, ethallor, ethalfluralin, etametsulfuron, ethaprochlor, ethidimuron, ethiofencarb, ethiolate, ethion, etiosine, ethiprol, etirimol, etoate-methyl, etobenzanide, etofumesate, ethohexadiol, etoprop, etoprofos, ethoxyphene, bromide (3-ethoxypropyl) Mercury, Ethoxyquin, Ethoxysulfuron, Ethylosate, Ethylane, Ethyl-DDD, Ethylene, Ethylene Dibromide, Ethylene Dichloride, Ethylene Oxide, Ethyl Format, Ethylcyne, Ethylmercury Acetate, Ethylmercury Bromide, Ethylmercury Chloride, Ethylmercury 2,3-Dihydroxypropyl Merck aptide, ethylmercury phosphate, N(ethylmercury)-p-toluenesulfonanilide, N-(ethylmercury)-p-toluenesulfonanilide, ethyl phosphate, ethinophene, ETM, ethnipromide, etobenzanide, ethophenprox, ethoxazole, etridiasol, etrymphos, eugenol, EXD, fampur, fenac, фенамидон, фенаминосульф, фенаминстробин, фенамифос, фенапанил, фенаримол, фенасулам, феназафлор, феназахин, фенбуконазол, фенбутатин оксид, фенхлоразол, фенхлорфос, фенклофос, фенклорим, фенатакарб, фенфлутрин, фенфурам, фенгексамид, фенидин, фенитропан, фенитротион, фенизон, феньюнтонг, фенобукарб , phenols, fenoprop, fenothiocarb, fenoxacrim, fenoxanil, fenoxaprop, fenoxaprop-P, fenoxasulfone, fenoxycarb, fenpiclonil, fenpicoxamide, fenpyrythrin, fenpropatrin, fenpropidine, fenpropymorph, fenpyrazamine, fenpyroximate, fenquinotrion, fenridafentherazone, fenpyrazine, fenpyroximate, fenquinotrion, fenridafentherazone, fenridafenzone, fenpyrazine , fenthion-ethyl, fentiaprop, fentin, fentrazamid, fentrifanil, fenuron, fenuron-TCA, fenvalerate, ferimzone, iron phosphate, ferrous sulfate, fipronil, flamprop, flamprop-M, флазасульфурон, флокумафен, флометохин, флоникамид, флорасулам, флорпирауксифен, флуакрипирим, флуазаиндолизин, флуазифоп, флуазифоп-Р, флуазолат, флуазурон, флубендиамид, флубензимин, флуброцитринат, флюкарбазон, флуцетосульфурон, флухлоралин, флукофурон, флуциклоксурон, флуцитринат, флудиоксонил, флуэнетил, флуэнсульфон, flufenacet, flufenerim, flufenican, flufenoxuron, flufenoxystrobin, flufenprox, flufenpyr, flufenzine, flufiprole, fluhexafon, fluindapir, flumetrin, flumetover, flumetralin, flumetsulam, flumezin, flumipropine, flumorph, fluometuron, fluopicolide, fluopyram, fluorobenzidic acid, , fluorochloridone, fluorodiphene, fluoroglycofen, fluoroimide, fluoromidin, fluoronitrofen, fluoroxypyr, fluothiuron, fluotrimazole, fluoxastrobin, flupoxam, flupropacil, flupropadine, flupropanate, flupyradifuron, flupyrsulfuron, fluquinconazole, fluralaner, flurazol, flure

- 19 040318 kol, flurenol, fluridone, flurochloridone, fluromidine, fluroxypyr, flurprimidol, flursulamide, flurtamon, flusilazole, flusulfamide, flutensin, flutiacet, fluthiamide, flutianil, flutolanil, flutriafol, fluvalinate, tau-fluxolvalinate, fluxamethopelamide, , fomesafen, fonofos, foramsulfuron, forchlorfenuron, formaldehyde, formparanate, fosamine, fosetil, fosmethylan, fospirate, fostiazate, fostietan, frontalin, phthalides, fuberidazole, flukaotsin, fukaom, ethoxifen-ethyl, fumarin, funaigekaoling, fufentiourea, furalan, furamethrinsil , furametpyr, furan tebufenoside, furatiocarb, furcarbanil, furconazole, cis-furconazole, furatrin, furfural, furilazole, furmecyclox, furofanate, furyloxifene, gamma-BHC, gamma-cyhalothrin, gammaHCH, genit, gibberellic acid, gibberellin A3, gibberellins, glyfluoro, glytor, glucochlorazole, glufosinate, glufosinate-R, glyodine, glyoxime, glyphosate, glyphosine, gosiplur, grandlur, griseofulvin, guanoctine, guazatin, halocrinate, ha Lauxifen, Halfenprox, Halofenozide, Halosafen, Halosulfuron, Haloxydin, HCA, HCB, HCH, Gamma-HCH, Hemel, Hempa, HEOD, Heptafluthrin, Heptenophos, Heptopargyl, Herbimycin, Herbimycin A, Heterophos, Hexachlor, Hexachlorane, Hexachloroacetone, Hexachlorobenzene, Hexachlorobutadiene , Hexachlorophene, Hexaconazole, Hexaflumuron, Hexafluoramine, Hexaflurate, Hexalur, Hexamide, Hexazinon, Hexylthiophos, Hexythiazox, HHDN, Golosulf, Homobrasinolide, Huanjunzuo, Hydramethylnon, Hydrarhafen, Hydrated Lime, Hydrogen Cyanamide, Hydrogen Cyanide, Hydroxyisoprene, Shydroxoprene hydroxyphenethyl alcohol, 8-hydroxyquinoline sulfate, hymexazole, hyquincarb, IAA, IBA, IBP, icaridin, imazalil, imazametabenz, imazamox, imazapic, imazapir, imazakhin, imazethapir, imazosulfuron, imibenconazole, imiciafos, imidacloprid, imidaclotiz, iminoctadine, imiprotrin, inabenfid, indanofan, indaziflam, indoxacarb, inezin, diatomaceous earth, iodobonil, iodocarb, iodophenphos, iodomethane, iodosulfuron, iofensulfuron, io xynil, ipazine, IPBC, IPC, ipconazole, ipfencarbazone, ipfentrifluconazole, iprobenfos, iprovalicarb, iprimidam, ipsdienol, ipsenol, IPSP, IPX, isamidophos, isazophos, isobenzane, isocarbamide, isocarbophos, isocyl, isodrin, isofenphos, isofenfos-methyl, isofetamide, isoflucypram, isolan, isomethiosin, isonoruron, isopamphos, isopolynate, isoprocarb, isoprocyl, isopropaline, isopropazole, isoprothiolan, isoproturon, isopyrazam, isopyrimol, isothioate, isothianil, isouron, isovaledione, isoxaben, isoxalorthol, isoxadifen, isoxapyrifop, isoxathion, isuron, ivermectin, ixoxaben, isopamphos, japonilur, japotrin, jasmolin I, jasmolin II, jasmonic acid, jiahuangchongzong, kumethoxystrobin, jiekaowan, jiekaoxy, jingangmicin A, iodfenphos, juvenile hormone I, juvenile hormone II, juvenile hormone III, cadetrin, kappabifenthrin, kappa-tefluthrin, carbutylate, caretazan, kasugamycin, kejunlin, kelevan, ketospiradox, diatomaceous earth, kinetin, kinoprene, S-kinoprene, kiralaxil, kresoxim methyl, kuikaoxy, lactofen, lambda-cyhalothrin, lancotrione, latilur, lead arsenate, lenacil, lepimectin, leptophos, sulfate lime, d-limonene, lindane, lineatin, linuron, lyrimphos, litlur, luplur, lufenuron, claciphos, lvfUmijvzhi, litidathione, M-74, M- 81, MAA, magnesium phosphide, malathion, maldison, maleic hydrazide, malonobene, MAMA, mancopper, mancozeb, mandestrobin, mandipropamide, matrine, mazidok, MCC, MCP, 1-MCP, MCPA, 2,4-MCPA, MCPA-thioethyl, MSRV, 2,4-MSRV, MSPP, mebenil, mecarbam, mecarbinzid, mecarfon, mecoprop, mecoprop-R, medimeform, medinoterb, medlur, mefenacet, mefenoxam, mefenpyr, mefentrifluconazole, mefluidide, megatomic acid, myricyl alcohol, melitoxin, MEMS, menasone, MEP, mepanipyrim, meperfluthrin, mephenate, mephospholane, mepiquat, mepronil, meptyldinocap, mercaptodimetur, mercaptophos, mercaptophos-thiol, mercaptothiol, mercuric(II) chloride, mercuric oxide, mercuric(I) chloride, merphos, merphos oxide, mesoprazine, mesosulfuron, mesotrione, mesulfen, mesulfenphos, metacresol, metaflumizone, metalaxyl, metal axyl-M, R-metalaxyl, metaldehyde, metam, metamifop, metamitron, metaphos, metaxone, metazachlor, metazosulfuron, metazoxolone, methcamifen, meconazole, metepa, metflurazone, metabenzthiazuron, metacriphos, metalpropaline, metam, metasulfocarb, metazole, metfuroxam, ethibenzuron, methidathione, methiobencarb, methiocarb, methiopyrisulfuron, methiothepa, methiozolin, methiuron, methocrotophos, metlocarb, methomethon, methomyl, methoprene, S-methoprene, methoprotrin, methoquin-butyl, methothrin, methoxychlor, 2-methoxyethylmercury chloride, methoxyphenone, methylmethoxyphenoside, methoxyphenoside, , methyl bromide, methyl eugenol, methyl iodide, methyl isophenephos, methyl isothiocyanate, methyl parathion, methyl acetophos, methyl chloroform, 1-methylcyclopropene, methyl dithiocarbamic acid, methyl dimron, methylene chloride, methyl mercaptophos, methyl mercapto phosoxide, methyl mercaptophostiol, methyl mercaptothybenzodifenate, methyl mercury diamide, methylneodecanamide, methylnitrophos, methyltriazothion, methiozolin, metiram-zinc, metobromuron, metofluthrin, e psilon-methofluthrin, metolachlor, S-metolachlor, metolcarb, methomethuron, methominostrobin, methosulam, methoxadiazon, methoxuron, metrafenone, metriam, metribuzin, metrifonate, metsulfax, metsulfuron, mevinfos, CMS, mieshuan, milbemectin, milbemycin, oxime, milneb , MIPC, mirex, MNAF, Moguchun, Molinat, Molosultap, Monalid, Momfluorotrin, Epsilonmomfluorotrin, Monisuron, Monoamitraz, Monochloroacetic acid, Monocrotophos, Monolinuron, Monomehypo, Monosulfiram, Monosulfuron, Monosultap, Monuron, Monuron-TCA, Morfamquat, Moroxidine, Morphothion, morzide, moxidectin, MRMS, MSMA, MTMS, a-multistriatin, muscalur, myclobutanil, myclozolin, myricyl alcohol, NAA, NAAm, nabam, naphthalofos, naphthalene, naphthaleneacetamide, a-naphthylacetic acid, naphthalic anhydride, naphthalophos, 1-naphthol, naphthoxyacetic acids, naphthylacetic acids, naphthylindane-1,3-diones, naphthyloxoacetic acids, naproanilide,

- 20 040318 propamide, napropamide-M, natamycin, NBPOS, neburea, neburon, nendrin, neonicotine, nichlorphos, niclofen, niclosamide, nicobifen, nicosulfuron, nicotine, nicotine sulfate, nifluridide, icomycins, NIP, nipyraclofen, nipyralofen, nitenpyram, nithiazine, nitraline, nitrapyrin, nitrilacarb, nitrofen, nitrofluorofen, nitrostyrene, nitrothal-isopropyl, nobormide, nonanol, norbormide, norea, norflurazon, nornicotine, noruron, novaluron, noviflumuron, NPA, nuarimol, nuranone, OCH, octa-chlorodipropyl ether, octilinone, 2(octylthio)ethanol, o-dichlorobenzene, ofuratz, ometoate, o-phenylphenol, orbencarb, orfralur, orthobencarb, ortho-dichlorobenzene, orthosulfamuron, oryktalur, orysastrobin, oryzalin, osthol, ostramon, ovatron, ovex, oxabethrinil, oxadiargyl, oxadiazon, oxadixyl, oxamate, oxamyl, oxapyrazole, oxasulfuron, oxathiapaproline, oxacyclomefon, oxin-copper, oxin-Cu, oxolinic acid, oxpoconazole, oxycarboxine, oxydemeton-methyl, oxydeprofos, oxydisulfotone, oxyenadenine, oxyfluorophen, ox Imatrine, Oxytetracycline, Oxythioquinox, PAC, Paclobutrazol, Paichundin, Palletrin, PAP, Para-Dichlorobenzene, Parafluron, Paraquat, Parathion, Parathion-methyl, Parinol, Parisian Green, PCNB, PCP, PCP-Na, p-Dichlorobenzene, PDJ, Pebulate , pedinex, pefurazot, pelargonic acid, penconazole, pencycuron, pendimethalin, penfenate, penflufen, penfluron, penoxalin, penoxulam, pentachlorophenolate, pentachlor phenyl laurate, pentanochlor, pentiopyrad, pentmethrin, pentoxazone, perchlordecone, perfluidone, permethrin, petoxamide, RNS, fenacryl, fenamacryl-ethyl, phenaminosulf, phenazine oxide, phenizopham, phencaptone, phenmedipham-ethyl, phenobenzuron, phenothiol, phenothrin, fenproxide, phentoate, 8-phenylmercury quinoline, phenylmercury urea, phenylmercury acetate, phenylmercury chloride, phenylmercuric pyrocatechol derivative, phenylmercuric nitrate, phenylmercury nitrate 2-phenylphenol, phosacetim, fosalon, fosamethine, fosazetim, fosazetine, foscyclotin, fosdifen, fosetil, phospholane, phospholane-methyl, phosglycine, fosnichlor, phosphamide, phosphami don, phosphine, phosphinothricin, phosphocarb, phosphorus, fostin, phoxim, phoxim-methyl, phthalide, phthalofos, phtalthrin, picarbutrazox, picaridin, picloram, picolinafen, picoxystrobin, pimaricin, pindone, piperalin, piperazine, piperonyl butoxide, piperonylcyclonene, piperophos, pyroctanil, piprotal, pyrimetaphos, pyrimicarb, pyriminyl, pyrimioxyphos, pyrimiphos-ethyl, pyrimiphos-methyl, pival, pivaldione, plifenate, PMA, PMP, polybutenes, polycarbamate, polychlorcamphene, polyethoxyquinoline, polyoxin D, polyoxins, polyoxorim, polythialan, potassium arsenite, potassium azide , potassium cyanate, potassium ethyl xanthate, potassium naphthenate, potassium polysulfide, potassium thiocyanate, pp'-DDT, pralletrin, prococene I, prococene II, prococene III, pretilachlor, primidophos, primisulfuron, probenazole, prochloraz, proclonol, procyazine, procymidone, prodiamine, profenofos, profluazol, profluralin, profluthrin, profoxidim, profurit-aminium, proglinazine, prohexadione, prohydrojasmone, promacyl, promecarb, prometon, prometrin, promurit, pronamide, propachlor, propapho c, propamidin, propamocarb, propanil, propafos, propaquizafop, propargite, propatrin, propazine, propetamphos, profam, propiconazole, propidine, propisochlor, propoxur, propoxycarbazone, propylizome, propyrisulfuron, propizamide, proquinazid, prosuler, prosulfaline, prosulfocarb, prosulfuron, protidathione, prothiocarb, prothioconazole, prothiophos, protoate, protrifenbut, proxane, primidodoph, prinachlor, psoralen, pidadone, pidiflumethofen, piflubumide, pymetrozine, pyracarbolide, pyraclophos, pyraclonil, pyraclostrobin, pyraflufen, pyrafluprol, pyramate, pyrametostrobin, pyraoxystrobin, pyrazolphotol, d pyrazolinate, pyrazon, pyrazophos, pyrazosulfuron, pyrazothion, pyrazoxyfen, pyresmethrin, pyrethrin I, pyrethrin II, pyrethrins, pyribambenz-isopropyl, pyribambenz-propyl, pyribencarb, pyribenzoxime, pyributicarb, pyriclor, pyridaben, pyridafol, pyridalyl, pyridafenthion, pyridine, pyridine, pyrifluquinasone, pyrifthalide, pyrimetaphos, pyrimethanil, pyrimicarb, pyrimidifen, pyriminobac , pyriminostrobin, pyrimiphos-ethyl, pyrimiphos-methyl, pyrimisulfan, pyrimitate, pyrinuron, pyriophenone, pyriprole, pyripropanol, pyriproxyfen, pyrisoxazole, pyrithiobac, pyrolane, pyrochilon, pyroxasulfone, pyroxulam, pyroxychlor, sayunmao, cassia, methylquinacetol, quinalos- Hinazamide, Hinclorak, Hinkanazole, Hynmerak, Khinmlamin, Khinofumelin, Hinometionate, Chinomide, Hinotion, Khinoxifen, Hintiofos, Hintozen, Hizalofop-R, Zyuinchzhi, Zyinin, Rafoxanid, Reenoferin, Medemide, Medemide, Medemid , d-trans-resmetrin, rodetanil, rhodojapanin-III, ribavirin, rimsulfuron, rizazole, R-metalaxyl, rodetanil, ronel, rotenone, riania, sabadila, saflufenacil, sajunmao, bismerthiazole copper salt, salicylanilide, saliflufen, sanguinarin, santonin, sarolaner , S-bioalethrin, shradan, sciliroside, sebutylazine, secbumeton, sedaxan, selamectin, semiamitraz, sesamex, sesamolin, season, setoxydim, sevin, S-hydroprene, shuangjiaankaolin, siduron, siglur, silafl ufen, silatrane, quartz airgel, silica gel, silthiopham, silthiophane, silvex, simazine, simeconazole, simeton, symetrin, synthophen, S-kinoprene, caustic lime, SMA, Smethoprene, S-metolachlor, sodium arsenite, sodium azide, sodium chlorate, cyanide sodium, sodium fluoride, sodium fluoroacetate, sodium hexafluorosilicate, sodium naphthenate, sodium orthophenylphenoxide, sodium pentachlorophenate, sodium pentachlorophenoxide, sodium o-phenylphenoxide, sodium polysulfide, sodium silicofluoride, sodium tetraborate, sodium tetrathiocarbonate, sodium thiocyanate, solan, sofamide, spinetoram, spinosad , spirodiclofen, spiromesifen, spirotetramat, spiroxamine, styrophos, streptomycin, strychnine, sulcatol, sulcofuron, sulcotrione, sulfalate, sulfentrazone, sulfiram, sulfluramide, sulfodiazole, sulfometuron, sulfosate, sulfosulfuron, sulfotep, sulfoxaflor, sulfoxide, sulfoxime sulglycapine, sulfosate, sulfprofos, sultropene, swep, 2,4,5-T, tau

- 21 040318 fluvalinate, tavron, tazimcarb, 2,4,5-TB, 2,3,6-TVA, TBTO, TBZ, TCA, TCBA, TCMTB, TCNB, TDE, tebuconazole, tebufenoside, tebufenpyrad, tebufloquine, tebupirimphos, tebutam , tebuthiuron, tecloftalam, teknazen, tecoram, tedion, teflubenzuron, tefluthrin, kappa-tefluthrin, tefuryltrione, tembotrione, temefos, tepa, TERR, tepraloxydim, teproloxydim, teralletrin, terbacil, terbucarb, terbuchlor, terbufos, terbumetone, terbutylazine, terbutrin, terbutol , terrachlor, terramycin, tetcyclacis, tetrachloroethane, tetrachlorvinphos, tetraconazole, tetradifon, tetradisul, tetrafluron, tetramethrin, tetramethylfluthrin, tetramine, tetranactin, tetraniliprol, tetrapion, tetrasul, thallium sulfate, tenylchlor, tetacypermethrin, thiabendazole, thiacloprid, thiadiazine, thiadifluoro, thiamethodine thiamethuron, thiapronil, thiazafluron, thiazfluron, thiazon, thiazopyr, ticrophos, tricyophene, thidiazimin, thidiazuron, thiencarbazone, thifensulfuron, thifluzamide, thimerosal, thimet, thiobencarb, thiocarboxime, thiochlorfenfim, dinitrobene thiocyanate ash, thiodan, thiodiazol-copper, thiodicarb, thiophanocarb, thiophanox, thiofluoximate, thiogempa, thiomersal, thiometon, thionazine, thiophanate, thiophanate-ethyl, thiophanate-methyl, thiophos, thioquinox, thiosemicarbazide, thiosultap, thioximing, thiamylotepa, thiosemicarbazide thiabendazole, thiadinil, thiafenacil, tiaozean, TIBA, thifatol, thiocarbazil, thioclorim, thioxazafen, thioximide, TMTD, tirpat, tolclofos-methyl, tolfenpyrad, tolprocarb, tolpyralate, tolylfluanid, tolylmercury acetate, tomarin, topramesone, toxafen, 2.4.5 -TP, 2,3,3-TPA, TPN, tralkoxydim, tralocitrin, tralometrin, tralopyril, d-trans-alletrin, d-trans-resmethrin, transpermethrin, tretamine, tri-allat, triacontanol, triadimefon, triadimenol, triafamon, tri -allate, triamiphos, triapentenol, triaraten, triarimol, triasulfuron, triazbutyl, triaziflam, triazophos, triazothion, triazoxide, tribasic copper chloride, tribasic copper sulfate, tribenuron, tribuphos, tributyltin oxide, tricamba, trichlamide, triclopyr, trichloretafos-3, trichloronate, trichlor trinitr benzenes, trichlorfon, triclopyr, triclopyricarb, tricresol, tricyclazole, tricyclohexylol hydroxide, tridemorph, tridifan, trietazine, triphenmorph, triphenofos, trifloxystrobin, trifloxysulfuron, trifludimoxazine, triflumesopyrim, triflumizole, triflumuron, trifluralin, triflusulfuron, tripofop, trifopsime, trihydroxy, trihydroxy3 ,5-triiodobenzoic acid, 2,3,5-triiodobenzoic acid, trimedlure, trimetacarb, trimeturon, trinexapak, triphenylstanum, triprene, tripropindan, triptolide, tritac, trithialan, triticonazole, tritosulfuron, trank-cal, toelin, uniconazole, uniconazole-R , urbacid, uredepa, valerate, validamycin, validamycin A, valifenalate, valone, vamidothione, vanguard, vaniliprol, vernolate, vitamin D3, warfarin, xiaochongliulin, xinjunan, fenaminstrobin, CMS, xylachlor, xylenols, xylylcarb, ximiazol, ishijing, zarylamide , zengxiaoan, zeta-cypermethrin, zinc naphthenate, zinc phosphide, zinc thiazole, zinc thiazole, zinc trichlorophenate, zinc trichlorophenoxide, zineb, zolaprofos, zoo coumarin, zoxamide, pyrametostrobin, zomihuanglong, 1-MCP, 1-methylcyclopropene, 1-naphthol, 1,2-dichloropropane, 1,3-D, 1,3-dichloropropene, 2iP, 2-methoxyethyl mercury chloride, 2(octylthio) ethanol, 2-phenylphenol, 2,3,3-TRA, 2,3,5triiodobenzoic acid, 2,3,6-TBA, 2,4-D, 2,4-DB, 2,4-DEB, 2, 4-DEP, 2.4-DES, 2.4-DP, 2.4-MCPA, 2.4MCPB, 2.4.5-T, 2.4.5-TB, 2.4.5-TP, (3-epoxypropyl)mercury bromide, 3,4-DA, 3,4-DB, 3,4-DP, 3,6-dichloropicolinic acid, 4-aminopyridine, 4-CPA, 4-CPB, 4-CPP, 4-hydroxide phenethyl alcohol, 8-hydroxyquinoline sulfate, 8-phenylmercury oxyquinoline, or salts, derivatives and mixtures thereof. However, the above lists of pesticides are exemplary and are not intended to limit the scope of the invention. Those skilled in the art will appreciate the possibility of using other pesticidal actives without departing from the scope of this invention.

According to an embodiment of the invention, the water-disintegrating granular composition comprises microcapsules containing the pesticidal active. Thus, in an embodiment, the pesticidal active may be contained within the polymeric wall of the capsule. According to an embodiment of the invention, the polymeric capsule wall is a polyurea capsule wall.

According to another embodiment, a water-disintegrating granular composition containing a water-insoluble nutrient or algae or pesticidal active of the invention has a lower bulk density compared to known granules, promotes faster disintegration of the granules, and also prevents the composition from settling in water. The bulk density of the water-disintegrating granules of the invention can be defined as the mass of the many particles contained in the granules divided by the total volume they occupy.

According to an embodiment of the invention, the bulk density of the water-disintegrating granules containing the water-insoluble material or the algae or the pesticidal active ingredient is less than 1.5 g/ml. According to an embodiment of the invention, the water-disintegrating granules have a bulk density of less than 1.4 g/ml. According to another embodiment of the invention, the water-disintegrating granules have a bulk density of less than 1.3 g/ml. According to an embodiment of the invention, the bulk density of the water-disintegrating granules is advantageously less than 1.2 g/ml. The bulk density of the granules is measured by standard methods such as the CIPAC handbook test, MT 186.

According to another embodiment, the water-disintegrating granular composition of the present invention has an improved true gravity compared to prior art granules. True density is the density of the granules themselves; it is defined as the mass of the granules divided by the true volume of the granules. According to an embodiment of the invention, the water-disintegrating granular composition has a true density of less than 2.5 g/ml. According to another embodiment of the invention, the water-disintegrating granular composition has a true density of less than 2.4 g/ml. The true density of the granules is measured by the method described below.

Equipment needed: 250 ml Le Chatelier flask with divisions 0-1 ml below expansion and 18-24 ml above expansion.

Kerosene or n-hexane.

Methodology.

1.1 Fill a Le Chatelier flask with kerosene or n-hexane to between 0-1 ml and equilibrate at room temperature in a water bath. Record the exact constant volume while the flask is in the water bath (V1).

1.2 Wipe the flask and clean the outside, place it on the balance and tare with the stopper.

1.3 The sample is carefully poured into the flask from the top until the diluent reaches the 20-24 ml mark. Record the weight of the added sample to the nearest 0.01 g (W).

1.4 Place the flask back into the water bath at room temperature and wait until a constant volume is observed. Record the exact constant volume while the flask is in the water bath (V2).

1.5 Calculate the true density (g/ml).

1.6 Calculations:

W

True Density TD=------g/mL

V2-V1

Abrasion resistance determines the wear resistance of a granular material. The water-disintegrating granular composition has adequate attrition resistance. Samples can be tested for abrasion according to CIPAC Handbook method MT 178 - Attrition resistance of granules. Before testing, the granules are sieved on a 125 µm sieve to remove fine particles. A known amount of these dedusted granules is transferred into a glass vial and subjected to rotational movements with the same number of glass beads. After rotation for a certain period, the abrasion resistance is determined by re-sifting on a 125 µm sieve and weighing the material contained on the sieve. According to another embodiment of the invention, a water-disintegrating granular composition containing a water-insoluble material or algae or a pesticidal active has improved abrasion resistance compared to known granules. In FIG. 2, which shows the water-dispersible granules containing sulfur as described in WO 2008084495 after packaging and transport, and FIG. 4, which shows a water-dispersible granular composition (410) of 70% sulfur + 15% zinc oxide, as described in WO 2012131702, it is seen that after production, processing, packaging or transportation, the granules crumble to a very small particle size, which leads to to loss of release control and leaching of nutrients in these water-dispersible granular forms compared to the water-dispersible granular compositions of the invention. According to an embodiment of the invention, the attrition resistance of the water-disintegrating granular composition is less than 50%.

According to an embodiment of the invention, the attrition resistance of the water-disintegrating granular composition is less than 60%. According to an embodiment of the invention, the attrition resistance of the water-disintegrating granular composition is less than 70%. According to an embodiment of the invention, the attrition resistance of the water-disintegrating granular composition is less than 80%. According to an embodiment of the invention, the abrasion resistance of the granules is at least 90%. According to another embodiment of the invention, the attrition resistance of the water-disintegrating granular composition is at least 95%. According to an embodiment of the invention, the water-disintegrating granular composition exhibits at least 98% abrasion resistance. According to an embodiment of the invention, the water-disintegrating granular composition exhibits abrasion resistance of at least 99%. The abrasion resistance of the granules can be determined using the standard CIPAC test.

A water-disintegrating granular agricultural composition containing a water-insoluble nutrient or algae or a pesticidal active ingredient, surprisingly, has a significant hardness. The hardness depends on other materials also used in combination with a water insoluble nutrient or algae or pesticide active ingredient. For example, the granules have a hardness less than or less than 5 N if organic substances or materials such as humic acid or fulvic acid are also present in the composition. According to an embodiment of the invention, the hardness of the granules is at least 1 N. According to an embodiment of the invention, the hardness of the water-degradable

- 23 040318 granular composition is at least 3 N. According to an embodiment of the invention, the hardness of the water-disintegrating granular composition is at least 5 N. According to an embodiment of the invention, the hardness of the granules is at least 10 N. According to an embodiment of the invention, the hardness of the disintegrate in water of the granular composition is at least 15 N. According to an embodiment of the invention, the hardness of the granules is at least 20 N. According to an embodiment of the invention, the hardness of the granules is at least 30 N. According to an embodiment of the invention, the hardness of the granules is at least 40 N In an embodiment of the invention, the hardness of the pellets is at least 50 N. The hardness of the pellets can be determined using testers such as Shimadzu, Brinell Hardness (Model AKB-3000), Mecmesin, Agilent, Vinsyst, Ametek, and Rockwell.

According to an embodiment of the invention, the water-disintegrating granules containing the water-insoluble material or the algae or the pesticidal active ingredient have a high disintegrability. Disintegration can be defined as the complete destruction of the granule upon contact with soil moisture or water. Samples can be tested for disintegration time according to CIPAC Handbook, MT 178 for Disintegration of tablets. To carry out the test, one whole, water-disintegrating granule is added to a volume of standard water specified by CIPAC and mixed gently for the specified tablet disintegration time. The suspension is then passed through a 2000 µm sieve. The absence of residue on the sieve indicates complete disintegration of the tablet. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 200 minutes. Disintegration is usually higher for those granules that are granulated for a longer time in a tray and/or screw granulator. It can also be higher if the tray granulator is running at high speed (higher RPM). The granules can be subjected to longer granulation in a fluid bed dryer, screw and trough granulator to produce more compact, nearly spherical, flat surfaced granules that will release the agrochemical over a longer period of time. Thus, it is possible to deliver compositions to provide plant nutrition or protection, depending on the plant, and to provide persistent plant protection and nutrition, depending on the crop growth cycle. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 150 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 120 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 100 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 90 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 80 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 70 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 60 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 50 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 40 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 30 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 20 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 10 minutes. According to an embodiment of the invention, the disintegration time of the water-disintegrating granules is less than 6 minutes. The disintegration time is determined using test equipment such as equipment manufactured by Electrolab Edutec, Arentek and Shimadzu.

According to an embodiment of the invention, the water-disintegrating granules containing the water-insoluble material or the algae or the pesticidal active ingredient have high sieve residue values in the wet screening method. The wet sieve residue score gives an estimate of the amount of undispersed material in granular compositions used as dispersions in water. The lower the wet sieve residue value, the better the dispersibility of the granular composition.

Samples can be tested for wet sieve residue according to CIPAC Handbook, MT 185 Wet Sieve Test. A sample of the composition is dispersed in water or allowed to completely disperse in water and the resulting suspension is transferred to a sieve and washed. The amount of material left on the sieve is determined by drying and weighing.

According to an embodiment of the invention, the water-disintegrating granules have a wet retention value on a 75 μm wet sieve of less than 30%. According to an embodiment of the invention, the water-disintegrating granules have a wet retention value on a 75 μm wet sieve of less than 20%. According to an embodiment of the invention, the water-disintegrating granules have a wet retention value on a 75 μm wet sieve of less than 10%. According to an embodiment of the invention, the granules capable of disintegrating in water have a value

- 24 040318 retention on a wet sieve with a hole size of 75 microns is less than 7%. According to an embodiment of the invention, the water-disintegrating granules have a retention value on a wet 75 µm sieve of less than 5%. According to an embodiment of the invention, the water-disintegrating granules have a wet retention value on a 75 μm wet sieve of less than 2%.

According to an embodiment of the invention, the water-disintegrating granules containing a water-insoluble material or an algae or a pesticidal active ingredient have a high dispersion. From Table. 5 it can be seen that these water-dispersible granular forms, according to an embodiment of the invention, have a higher dispersion in comparison with the water-dispersible granules of the invention, which leads to rapid uptake by plants and thus to a decrease in their availability over a long period of the crop life cycle. Dispersibility can be defined as the ability of the granules to disperse when added to water. Water-disintegrating granules can be analyzed for dispersibility in accordance with CIPAC Handbook, MT 174 Test for Dispersibility. A known number of samples of granules are added to a certain volume of water and mixed with mechanisms to form a suspension. After settling for a short period of time, the top nine-tenths of the portion is discarded and the remaining one-tenth is dried and gravimetrically determined. This method is essentially an abbreviated suspension test and is suitable for determining the ease with which a granule is uniformly dispersed in water.

According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 10%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 20%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 30%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 40%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 50%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 60%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 70%. According to an embodiment of the invention, the water-disintegrating granules have a fineness of at least 80%. Such a wide range of dispersion may be due to the fact that the composition is subjected to a longer granulation; it also depends on the percentage of nutrients, algae or pesticides in the composition. For example, granules subjected to longer granulation or faster rotation in a trough granulator may become smoother, more compact, and disperse more slowly than granules subjected to a short granulation period at a slower rotation speed of the granulator (less rpm).

According to an embodiment of the invention, it is desirable that the granules of the composition disperse slowly and release the agrochemical over a period of time. According to an embodiment of the invention, in the case of early maturing crops or crops that require nutrition or protection during the first 15 days of the life cycle, it may be desirable that the granules have a higher dispersion.

According to an embodiment of the invention, the water-disintegrating granules containing the water-insoluble material, the algae, or the pesticidal active ingredient have a proper suspendability. Suspensibility can be defined as the amount of active ingredients (water-insoluble nutrients) suspended after some time in a column of liquid of a certain height and expressed as a percentage of the amount of the ingredient in the original suspension. Water-soluble granules can be tested for suspension in accordance with CIPAC Handbook, MT 184 Test for Suspensibility, whereby a suspension of known concentration is prepared in CIPAC standard water, placed in a fixed measuring cylinder at a constant temperature and left still for certain time. The top 9/10 portions are discarded, and the remaining 1/10 is analyzed chemically, gravimetrically or by solvent extraction and the suspension is calculated.

According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 5%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 10%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 20%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 30%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 40%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 50%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 60%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 70%. According to an embodiment of the invention, the water-disintegrating granules have a suspension of at least 80%.

- 25 040318

According to an embodiment of the invention, the water-disintegrating granules containing the water-insoluble material or the algae or the pesticidal active ingredient are polygonal, spherical, oval, or any polygonal shape without affecting the observed good performance. According to an embodiment of the invention, the water-disintegrating granules are predominantly spherical in shape.

According to an embodiment of the invention, the agrochemical adjuvants contain surfactants, solvents, binders, disintegrants, inert fillers, pH stabilizers, lyophilizers, adhesives, antifoam agents, carriers, antimicrobial agents, antifreeze agents, antioxidants, preservatives and suppressants. agglomeration. However, those skilled in the art will appreciate the possibility of using additional agrochemically acceptable adjuvants without departing from the scope of the invention. These agrochemically acceptable adjuvants are commercially produced and marketed by various companies.

According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 99.9% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 99% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 95% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 90% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 80% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 70% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 60% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 50% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 40% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 30% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 20% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 10% of the total weight of the composition. According to an embodiment of the invention, the agrochemical adjuvants are present in a concentration range of at least 5% of the total weight of the composition.

According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 85% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 75% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 60% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 50% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 40% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 30% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of from 0.1 to 20% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of 0.1 to 10% m/m of the total composition. According to an embodiment of the invention, surfactants are present in an amount of 0.1 to 5% m/m of the total composition.

In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 99:1 and 1:99. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 90:1 and 1:90. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 80:1 and 1:80. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 70:1 and 1:70. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 60:1 and 1:60. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 50:1 and 1:50. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 40:1 and 1:40. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 30:1 and 1:30. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 20:1 and 1:20. In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 10:1 and 1:10.

In an embodiment, the ratio of algae to agrochemically acceptable excipients is between 5:1 and 1:5.

In an embodiment, the ratio of algae to surfactants or binders or disintegrants is between 50:1 and 1:30.

In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 19:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 18:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 17:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 16:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 15:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 14:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 13:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 12:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 11:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 10:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 9:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 8:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 7:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 6:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 5:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 4:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 3:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 2:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:1. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:2. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:3. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:4. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:5. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:6. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:7. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:8. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:9. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:10. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:11. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:11. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:12. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:13. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:14. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:15. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:16. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:17. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:18. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:19. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:20. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:25. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:30. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:35. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:40. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:45. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:50. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:55. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:60. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:65. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:70. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:75. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:80. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:85. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:90. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:95. In an embodiment, the ratio of algae to surfactants or binders or disintegrants is 1:99. However, the ratios indicated here are only exemplary and will be appreciated by those skilled in the art.

According to an embodiment of the invention, agrochemical adjuvants include surfactants, diluents, disintegrants, and binders. According to an embodiment of the invention, the agrochemical adjuvants contain at least one of surfactants and binders. According to an embodiment of the invention, surfactants include dispersants, wetting agents, and emulsifiers. According to another embodiment of the invention, the surfactants used in the composition include one or more anionic, nonionic, cationic, and amphoteric surfactants. However, those skilled in the art will appreciate the possibility of using other surfactants without departing from the scope of the invention.

Anionic surfactants include, but are not limited to, one or more of the following: fatty acid salt, benzoate, polycarboxylate, alkyl sulfuric acid ester salt, alkyl ether sulfates, alkyl sulfate, alkylaryl sulfate, alkyl diglycol ether sulfate, sulfuric acid ester alcohol salt, alkyl sulfonate, alkyl arylsulfonate, арилсульфонат, лигносульфонат, лкилдифенилэфирдисульфонат, полистиролсульфонат, соль эфира алкилфосфорной кислоты, алкиларилфосфат, стирларилфосфат, сульфонатдокузаты, соль полиоксиэтиленалкильного эфира серной кислоты, полиоксиэтиленалкиларилэфирсульфат, алкилсаркозинаты, натриевая соль альфа олефинсульфоната, алкилбензолсульфонат или его натриевая соль, кальциевая соль, лауроилсаркозинат натрия, сульфосукцинат, полиакрилаты и acids and sodium salts free from them, salt of polyoxyethylene alkyl aryl ester of sulfuric acid ester, polyoxyethylene alkyl ether phosphate, salt of polyoxyethylene alkyl aryl ester of phosphoric acid, sulfosuccinate - mono- and other di esters, phosphate esters, alkyl naphthalenesulfonate - isopropyl and butyl derivatives, alkyl ether sulfates - sodium and ammonium salts; alkyl aryl ether phosphates, ethylene oxide and its derivatives, polyoxyethylene aryl ester salt of phosphoric acid ester, mono-alkyl sulfosuccinates, aromatic hydrocarbon sulfonates, 2-acrylamide-2-methylpropane sulfonic acid, ammonium lauryl sulfate, ammonium perfluorononanoate, docusate, disodium cocoamphodiacetate, magnesium laureth sulfate, MBAS, perfluorobutane sulfonic acid acid, carboxylates, perfluorooctane sulfonic acid, perfluorooctanoic acid, phospholipids, potassium lauryl sulfate, soap, soap substitute, sodium alkyl sulfates, sodium dodecyl sulfate, sodium dodecylbenzenesulfonate, sodium laurate, sodium laureth sulfate, sodium lauroyl sarcosinate, sodium myreth sulfate, sodium nonaloyloxybenzenesulfonate, sodium pareth sulfate, alkyl carrates, steaboxylates sodium, alpha-olefin sulfonate, sulfolipids, naphthalenesulfonates, alkylnaphthalenesulfonate salts of fatty acids, naphthalenesulfonate condensates - sodium salt, fluorocarboxylates, fatty alcohol sulfates, alkylnaphthalenesulfonate condensates - sodium salt, formaldehyde-condensed naphthalenesulfonic acid or formaldehyde-condensed alkylnaphthalenesulfonic acid salt; or their salts and derivatives.

Non-ionic surfactants include one or more of the following, but

- 28 040318 are not limited to: polyol esters, polyol fatty acid esters, polyethoxylated ethers, polyethoxylated alcohols, ethoxylated and propoxylated fatty alcohols, ethoxylated and propoxylated short chain alcohols, EO/PO copolymers, di-, tri-block copolymers; block copolymers of polyethylene glycol and polypropylene glycol, poloxamers, polysorbates, alkyl polysaccharides such as alkyl polyglycosides and mixtures thereof, amine ethoxylates, sorbitol fatty acid esters, ethylene glycol and glycerol esters, glucose dialkyl ethers, sorbitan alkyl esters, sodium talovate, polyoxyethylene glycol, sorbitan alkyl esters, derivatives sorbitan, sorbitol fatty acid esters (Spans) and their ethoxylated derivatives (Tweens), and sucrose fatty acid esters, alkyl polyglycoside, cetomacrogol 1000, cetostearyl alcohol, cetyl alcohol, DEA cocamide, MEA cocamide, decylglucoside, decylpolyglucose, glycerol monostearate, IGEPAL CA630 , Isocetet-20, Lauryl Glucoside, Maltosides, Monolaurin, Mycosubtilin, Narrow Band Ethoxylate, Nonidet P-40, Nonoxynol-9, Nonoxynol, NP-40, Octaethylene Glycol Monodecyl Ether, N-Octyl Beta-O-Thioglucopyranoside, Octyl Glucoside, Oleyl Alcohol, Sunflower Seed Glycerides PEG-10, pentaethylene glycol monodecyl ether, polidocanol, poloxamer, Loxamer 407, Polyethoxylated Thalamine, Polyglycerol Polyricinoleate, Polysorbate, Polysorbate 20, Polysorbate 80, Sorbitan, Sorbitan Monolaurate, Sorbitan Monostearate, Sorbitan Tristearate, Stearyl Alcohol, Surfactin, Triton X-100, Tween-80, Polyethylene Glycol, Glyceryl Laureate, Lauryl Ethanol, Nonoxyphenyl Glucoside , nonylphenol polyglycol ethers, castor oil ethoxylate, polyglycol ethers, ethylene oxide and propylene oxide polyadducts, block copolymers of polyalkylene glycol ether and hydroxystearic acid, block copolymer of ethylene oxide and propylene oxide, tributylphenoxypolyethoxyethanol, octylphenoxypolyethoxyethanol, it-propoxylated tristyryltan acid esters, ethoxylated alcohol sorbitan, polyoxyethylene sorbitan , fatty acid esters of glycerol, fatty acid polyglyceride, polyglycol fatty acid alcohol ester, acetylene glycol, acetylenic alcohol, oxyalkylene block polymer, polyoxyethylene alkyl ether, polyoxyethylene alkylaryl ether, polyoxy ether ethylene styrylaryl, polyoxyethylene glycol alkyl ether, polyethylene glycol, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene glycerol fatty acid ester, alcohol ethoxylate - from C6 to C16/18 alcohols, linear and branched, alcohol alkoxylates - various hydrophobes and different content and ratio of EO /PO, fatty acid esters - mono- and diesters; lauric, stearic and oleic; esters of glycerol - with and without EO; lauric, stearic, cocoa butter and tall oil derivatives, ethoxylated glycerin, sorbitan esters - with and without EO; based on lauric, stearic and oleic acids; mono and trimesters, castor oil ethoxylate - from 5 to 200 mol EO; non-hydrogenated and hydrogenated, polyethylene glycol - 200, 300, 400, 600, 1450, 3350 and 8000, methyl capped polyethylene glycol - 350 and 550, block polymers - liquid, pasty and solid; wide range of EO/PO ratios, alkyl polyglycosides, amine oxides - ethoxylated and non-ethoxylated; alkyl dimethyl, fatty amine ethoxylate - coco, tall stearyl, oleyl amines, polyoxyethylene hydrogenated castor oil or polyoxypropylene fatty acid ester; their salts or derivatives and mixtures.

Amphoteric or zwitterionic surfactants include, but are not limited to, one or more of the following: betaine, betaines - cocoa and laurylamidopropyl betaines, cocoalkyldimethylamine oxides, betaine alkyldimethylbetaines; C8-C18, alkyl dipropionates - sodium lauriminodipropionate, cocoamidopropylhydroxysulfobetaines, imidazolines, phospholipids, phosphatidylserine, phosphatidylethanolamine, phosphatidylcholine and sphingomyelins, lauryldimethylamine oxide, alkylamphoacetates and proprionates, alkylampho(di)acetates, block copolymer of polyalkylene glycol ether ester, stearin hydroxylates (PEG) and also , lecithin and ethanolamine fatty amides; or their salts and derivatives.

Cationic surfactants include, but are not limited to, one or more of the following: dialkyldimethylammonium chlorides, alkylmethylethoxylated ammonium chlorides or salts, dodecyl-, coco-, hexadecyl-, octadecyl-, octadecyl/begenyl-, behenyl-, cocamidopropyl-, trimethylammonium chloride ; coco-, stearyl-, bis (2-hydroxyethyl) methylammonium chloride, benzalkonium chloride, alkyl-, tetradecyl-, octadecyldimethylbenzylammonium chloride, dioctyl-, di (octyldecyl) -, didecyl-, dihexadecyldistearyl-, di (hydrogenated tallow) - dimethylammonium chloride, di ( hydrogenated tallow)-benzyl-, trioctyl-, tri(octyldecyl)-, tridodecyl-, trihexadecylmethylammonium chloride, dodecyltrimethyl-, dodecyldimethylbenzyl-, di-(octyldecyl)dimethyl, didecyldimethylammonium bromide, quaternized aminoethoxylates, behentrimonium chloride, benzalkonium chloride, benzododecinium chloride, benzalkonium bromidedecinium , бронидокс, четвертичные аммониевые соли, карбетопендециния бромид, цеталкония хлорид, цетримония бромид, цетримония хлорид, цетилпиридиния хлорид, дидецилдиметиламмония хлорид, диметилдиоктадециламмония бромид, диметилдиоктадециламмония хлорид, домифенбромид, лаурилметилглюцет-10, гидроксипропилдимония хлорид, октенидиндигидрохлорид, олафлур, N-олеил-1, 3-pronαndiαmin, pachutoxin, stearalkonium chloride, tetramethylammonium g hydroxide, tonsonium bromide; salts or derivatives of these compounds.

According to an embodiment of the invention, the dispersants used in the degradable

- 29 040318 water granular composition containing water-insoluble material, algae or pesticidal active substance, include one or more of the following compounds: polyvinylpyrrolidone, polyvinyl alcohol, lignin sulfonate, phenolnaphthalene sulfonate, alkali metals, alkaline earth metals and ammonium salts of lignosulfonic acid, derivatives lignin, lignosulfonates, sodium lignosulfonates, naphthalenesulfonic acids, phenol sulfonic acid, dibutylnaphthalenesulfonic acid, alkylaryl sulfonates, alkyl sulfonates, alkyl sulfonates, fatty alcohol sulfates, fatty acids and sulfated fatty alcohol glycol ethers, polyoxyethylene alkyl ethers, dioctyl sulfosuccinate, lauryl sulfate, ethylene styryloxy ether sulfate, polyphenyloxyether salts, and the like, alkali metal salts, ammonium or amine salts, polyoxyethylene alkylphenyl ether, polyoxyethylene styrylphenyl ether, polyoxyethylene alkyl ethers or sorbitan and polyoxyethyl alkyl ethers ene, etc., a mixture of sodium salt of naphthalenesulfonic acid, urea formaldehyde condensate and sodium salt of alkylphenols ethoxylated with phenol sulfoformaldehyde condensate, ethoxylated fatty acids, alkoxylated linear alcohols, polycyclic aromatic sulfonates, sodium alkylarylsulfonates, glyceryl ethers, ammonium salts of maleic anhydride copolymers, maleic copolymers , phosphate esters, condensation products of arylsulfonic acid and formaldehyde, products of addition of ethylene oxide and fatty acid esters, salts of products of addition of ethylene oxide and fatty acid esters, formalin condensate of naphthalenesulfonates and alkylnaphthalenesulfonates, condensed naphthalene sulfonate, naphthalene-formaldehyde condensates, sodium salt of isodecylsulfosuccinic acid half-ester, polycarboxylates, sodium alkylbenzenesulfonates , sodium salts of sulfonated naphthalene, ammonium salts of sulfonated naphthalene, salts of polyacrylic acid, salts of phenolsulfonic acid and salts of naphthalenesulfonic acid, sodium salts of condensed phenolsulfonic acid, as well as naphthalenesulfonate-formaldehyde condensates, sodium naphthalenesulfonate-formaldehyde condensates, tristyrylphenolethoxylate phosphate esters; aliphatic alcohol ethoxylates; alkyl ethoxylates; EO-PO block copolymers; graft copolymers, ammonium salts of sulfonated naphthalene, salts of polyacrylic acids, salts of phenolsulfonic acids and salts of naphthalenesulfonic acids. Commercially available dispersants include Morwet D425 (sodium naphthalene formaldehyde condensate, e.g. from Witco Corporation, USA), Morwet EFW sulfated alkyl carboxylate and alkyl naphthalene sulfonate sodium salt, Tamol PP (sodium salt of phenolsulfonic acid condensate), Reax 80N (sodium lignosulfonate), Wettol D1 sodium alkylnaphthalene sulfonate (eg from BASF). However, those skilled in the art will appreciate the possibility of using various dispersants without departing from the scope of the invention. These dispersants are manufactured commercially and sold by various companies.

According to an embodiment of the invention, the wettable agents used in the water-disintegrating granular composition containing the water-insoluble material or algae or pesticidal active ingredient include one or more phenolnaphthalenesulfonates, alkylnaphthalenesulfonates, sodium alkylnaphthalenesulfonates, sodium salts of sulfonated alkyl carboxylates, polyoxyalkyl ethylphenols, polyoxyethoxylated fatty alcohols , polyoxyethoxylated fatty amines, lignin derivatives, alkanesulfonates, alkylbenzenesulfonates, salts of polycarboxylic acids, salts of sulfosuccinic acid esters, alkylnaphthalenesulfonates, alkylbenzenesulfonates, alkylpolyglycol ether sulfonates, alkyl ether phosphates, alkyl ether sulfates and alkylsulfosuccinic monoesters. However, those skilled in the art will appreciate the possibility of using different wettable agents without departing from the scope of the invention. These wetted products are manufactured commercially and sold by various companies.

Commercially available emulsifiers include among others

Atlas G5000, TERMUL

5429, TERMUL 2510, ECOTERIC®, EULSOGEN® 118, Genapol®X, Genapol®OX -080, Genapol® C 100, Emulsogen® EL 200, Arlacel P135, Hypermer 8261, Hypermer B239, Hypermer B261, Hypermer B246sf, Solutol HS 15 , Promulgen™ D, Soprophor 796IP, Soprophor TSP/461, Soprophor TSP/724, Croduret 40, Etocas 200, Etocas 29, Rokacet R26, CHEMONIC OE-20, Triton™ N-101, Tween 20, 40, 60, 65, 80, Span20, 40, 60, 80, 83, 85, 120, Brij®, Triton™ Atlox 4912, Atlas G5000, TERMUL 3512, TERMUL 3015, TERMUL

- 30 040318

5429, TERMUL 2510, ECOTERIC®, ECOTERIC® T85, ECOTERIC® T20, TERIC 12A4, EULSOGEN® 118, Genapol®X, Genapol®OX -080, Genapol® C 100, Emulsogen® EL 200, Arlacel P135, Hypermer 8261, Hypermer B239, Hypermer B261, Hypermer B246sf, Solutol HS 15, Promulgen™ D, Soprophor 796IP, Soprophor TSP/461, Soprophor TSP/724, Croduret 40, Etocas 200, Etocas 29, Rokacet R26, CHEMONIC OE-20, Triton™ N- 101, Tween 20, 40, 60, 65, 80 and Span 20, 40, 60, 80, 83, 85, 120 can also be used.

However, those skilled in the art will appreciate the possibility of using other emulsifiers without departing from the scope of the invention. These emulsifiers are manufactured commercially and sold by various companies.

According to an embodiment of the invention, the binders that can be used in the composition containing the water-insoluble material or the algae or the pesticidal active ingredient are water-soluble binders. In an embodiment, illustrative examples of water-insoluble binders that can be used in a water-disintegrating granular composition can be any one or more carbohydrates such as monosaccharides, disaccharides, oligosaccharides, and polysaccharides; proteins; lipids; glycolipids; glycoproteins, lipoproteins; and their combinations and derivatives. Hydrocarbon binders may include one or more of the following: glucose, mannose, fructose, galactose, sucrose, lactose, maltose, xylose, arabinose, sorbitol, mannitol, trehalose, raffinose, stachyose, fructooligosaccharides, amylose, amylopectin, modified starches, cellulose , hemicellulose, pectins, hydrocolloids and mixtures thereof.

Binders may also include synthetic organic water soluble polymers such as ethylene oxide polymers or copolymers, propylene oxide copolymer, polyethylene glycols, polyethylene oxides, polyacrylamides, polyacrylates, polyvinylpyrrolidone, polyalkylpyrrolidone, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl acrylates, polylactic acid, polyethoxylated fatty acids, polyethoxylated fatty alcohols and latex.

Binders may also include corn syrup; celluloses such as carboxymethylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxymethylcellulose, hydroxyethylpropylcellulose, methylhydroxyethylcellulose, methylcellulose; starches such as amylose, SeaGel, starch acetates, starch hydroxyethyl esters, ionic starches, long chain alkyl starches, dextrins, amine starches, phosphate starches and dialdehyde starches; vegetable starches such as corn starch and potato starch; other carbohydrates such as pectin, amylopectin, xylan, xanthan gum, starch, agar, alginic acid, phycocoloids, chitin, gum arabic, guar gum, karaya gum, gum tragacanth, and locust bean gum.

Binders may also include complex organics such as phenylnaphthalenesulfonate, lignin and nitrolignin; lignin derivatives such as lignosulfonate salts, including, for example, calcium lignosulfonate and sodium lignosulfonate, and complex carbohydrate-based compositions containing organic and inorganic ingredients such as molasses.

According to another embodiment of the invention, the binders may also include protein binders, which are selected on the basis of solubility and may include one or more simple proteins, conjugated proteins or protein derivatives, water-soluble proteins, acidic proteins, basic proteins, or derivatives thereof. According to another embodiment of the invention, appropriate protein binders may include one or more of the following: albumin, histone, protamine, prolamine, albuminoids, phosphoprotein, mucoprotein, chromoprotein, lactose, proteinase, pyruvate dehydrogenase, ribonuclease, flavoproteins, cytochrome C, ceruloplasmin, myoglobin , lysozyme, proteoses, peptones, chymotrypsin; lactate dehydrogenase, subtilisin, trypsin, actin, myosin, ricin, lectin, collagen, fibroin, adrenaline, elastin; soy extract, zein; ovalbumin and gamma globulin or their derivatives. However, those skilled in the art will appreciate the possibility of using various binders without departing from the scope of the invention.

The binder may be present in an amount of 0.1 to 50% by weight of the total dry weight of the water-disintegrating granular composition. According to an embodiment of the invention, the binder is present in an amount of 0.1 to 40% by weight of the total dry weight of the water-disintegrating granular composition. According to an embodiment of the invention, the binder is present in an amount of 0.1 to 30% by weight of the total dry weight of the water-disintegrating granular composition. According to an embodiment of the invention, the binder is present in an amount of 0.1 to 20% by weight of the total dry weight of the water-disintegrating granular composition. According to an embodiment of the invention, the binder is present in an amount of 0.1 to 15% by weight of the total dry weight of the water-disintegrating granular composition. According to an embodiment of the invention, the binder is present in an amount of 0.1 to 10% by weight of the total dry weight of the water-disintegrating granular composition.

- 31 040318

In an embodiment, the suspending agents used in the water-disintegrating granular composition include hydrocarbons. These carbohydrates may include one or more of the following: glucose, mannose, fructose, galactose, sucrose, lactose, maltose, xylose, arabinose, sorbitol, mannitol, trehalose, raffinose, stachyose, fructooligosaccharides, amylose, amylopectin, modified starches, cellulose, hemicellulose, pectins, hydrocolloids and mixtures thereof. According to an embodiment of the invention, the suspending agents are present in an amount of from 0.1 to 50% m/m of the total composition. According to an embodiment of the invention, the suspending agents are present in an amount of from 0.1 to 30% m/m of the total composition. According to an embodiment of the invention, the suspending agents are present in an amount of from 0.1 to 15% m/m of the total composition. According to an embodiment of the invention, the suspending agents are present in an amount of 0.1 to 10% m/m of the total composition. According to an embodiment of the invention, the suspending agents are present in an amount of 0.1 to 5% m/m of the total composition.

According to an embodiment of the invention, the disintegrants may be selected from, but are not limited to, one or more of the following: inorganic water-soluble salts, eg sodium chloride, nitrate salts; water-soluble organic compounds such as urea, agar, hydroxypropyl starch, carboxymethyl starch ether, tragacanth, gelatin, casein, microcrystalline cellulose, cross-linked sodium carboxymethylcellulose, calcium carboxymethylcellulose and calcium carboxymethylcellulose, sodium tripolyphosphate, sodium hexametaphosphate, metal stearates, cellulose powder, dextrin, metacrystal copolymer, Polyplasdone® XL-10 cross-linked polyvinylpyrrolidone, poly(vinylpyrrolidone), polyaminocarboxylic acid chelates, sulfonated styrene-isobutylene-mallein-anhydrite copolymer, methacrylate polyacrylate salts, polyacrylonitrile starch graft copolymer, sodium, potassium bicarbonates/carbonates or mixtures or salts thereof with acids such as citric and fumaric acids, or their salts, derivatives. However, those skilled in the art will appreciate the possibility of using other disintegrants without departing from the scope of the invention. These disintegrants are commercially produced and sold by various companies.

According to an embodiment of the invention, adhesives include, but are not limited to, one or more of the following compounds: paraffin, terpene, polyamide resin, polyacrylate, polyoxyethylene, wax, polyvinyl alkyl ether, alkylphenol formalin condensate, fatty acids, latex, aliphatic alcohols, vegetable oils, for example, cottonseed, mineral oils, petroleum distillates, modified trisiloxanes, polyglycol, polyesters, clatarates, synthetic resin emulsion, or salts or derivatives thereof. However, those skilled in the art will appreciate the possibility of using other adhesives without departing from the scope of the invention. These adhesives are manufactured commercially and sold by various companies.

According to an embodiment of the invention, lyophilizers may include, but are not limited to, one or more of the following compounds: cellulose powder, dextrin, modified starch, polyaminocarboxylic acid chelates, crosslinked poly(vinylpyrrolidone), styrenic maleic acid copolymer, (meth)acrylic copolymer acids, a polyester polymer of a polyhydric alcohol with a dicarboxylic anhydride, a water-soluble salt of polystyrenesulfonic acid, fatty acids, latex, aliphatic alcohols, vegetable oils such as cottonseed or inorganic oils, petroleum distillates, modified trisiloxanes, polyglycol, polyesters, clatarates or their salts and derivatives. However, those skilled in the art will appreciate the possibility of using other lyophilizers without departing from the scope of the invention. These lyophilizers are manufactured commercially and sold by various companies.

According to an embodiment of the invention, preservatives may include, but are not limited to, one or more of bactericides, antifungals, biocides, antimicrobials. Non-limiting examples of preservatives include one or more of the following: benzoic acid, its esters and salts, para-hydroxybenzoic acid (parabens), its esters and salts, propionic acid and its salts, salicylic acid and its salts, 2,4-hexadienoic acid ( sorbic acid) and its salts, formaldehyde and paraformaldehyde, 2-hydroxybiphenyl ester and its salts, 2-zinxulfidopyridine N-oxide, inorganic sulfites and bisulfite, sodium iodide, 1,2-benzisothiazolin-3-one, chlorobutanol, dehydroacetic acid, formic acid, 1,6-bis(4-amidino-2-bromopheoxy)-n-hexane and its salts, 10undecylenic acid and its salts, 5-amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine, 5 -bromo5-nitro-1,3-dioxane, 2-bromo-2-nitropropane-1,3-diol, 2,4-dichlorobenzyl alcohol, N-(4-chlorophenyl)N'-(3,4-dichlorophenyl)urea , 4-chloro-m-cresol, 2,4,4'-trichloro-2'-hydroxydiphenylether, 4-chloro 3,5 dimethylphenol, 1,1'-methylene-bis(3-(1-hydroxymethyl-2,4 -dioxymidazolin-5-yl)urea), poly(hexamethylenediguanide)hydrochlo rida 2-phenoxyethanol, hexamethylenetetramine, 1(3-chloroalyl)-3,5,7triaza-1-azonium-adamantane chloride, 1(4-chlorophenoxy)-1-(1 H-imidazol-1-yl)-3,3- dimethyl-2-butanone, 1,3bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione, benzyl alcohol, octopirox, 1,2-dibromo-2,4dicyanobutane, 2,2'-methylenbis(6-bromo -4-chlorophenolam), bromochlorophene, dichlorophene, 2-benzyl-4chlorophenolam, 2-chloroacetamide, chlorhexidine, chlorhexidine acetate, chlorhexidine gluconate, chlorhexidine hydrochloride, 1-phenoxypropan-2-ol, N-alkyl (C ₁₂ -C ₂₂ ) trimethylammonium bromide and chloride

- 32 040318

4,4-dimethyl-1,3-oxazolidine, N-hydroxymethyl-N-(1,3-di(hydroxymethyl)-2,5-dioxoimidazolin-4-yl)N'-hydroxymethylurea, 1,6-bis(4 -amidinophenoxy)-n-hexane and its salts, glutaraldehyde, 5ethyl-1-aza-3,7-dioxabicyclo(3.3.0)octane, 3-(4-chlorophenoxy)propane-1,2-diol, hyamine, alkyl (C ₈ -C ₁₈ ) dimethylbenzylammonium chloride, alkyl (C ₈ -C ₁₈ ) dimethylbenzylammonium bromide, alkyl (C ₈ -C ₁₈ ) dimethylbenzylammonium saccharin, benzyl polyformal, 3-iodo-2-propynylbutylcarbamate, sodium hydroxymethylaminoacetate, cetyltrimethylammonium bromide, cetylpyridinium chloride and 2H isothiazol-3-one derivatives (so-called isothiazolone derivatives), such as alkylisathiazolones (e.g. 2methyl-2H-isothiazol-3-one, MIT; chloro-2-methyl-2H-isothiazol-3-one, CHIT), benzoisothiazolones (e.g., 1,2-benzoisothiazol-3(2H)-one bit, commercially available as Proxel® species from ICI) or 2-methyl4,5-trimethylene-2H-isothiazol-3-one (MTIT), propionic acid, C1- _C4 alkyl parahydroxybenzoate, dichlorophene or salts and derivatives thereof. However, those skilled in the art will appreciate the possibility of using various preservatives without departing from the scope of the invention. These preservatives are manufactured commercially and sold by various companies. According to an embodiment of the invention, the preservative is present in an amount of 0.1 to 20% m/m. According to an embodiment of the invention, the preservative is contained in an amount of from 0.1 to 10% m/m of the total composition.

According to an embodiment of the invention, the carriers used in the water-disintegrating granular composition further comprise one or more solid carriers, liquid carriers, or excipients. In another embodiment, carriers include mineral carriers, vegetable carriers, synthetic carriers, and water-soluble carriers. However, those skilled in the art will appreciate the possibility of using other carriers without departing from the scope of the invention. These media are commercially produced and sold by various companies.

Solid carriers include natural minerals such as quartz, clay, kaolinite, pyrophyllite, sericite, talc (talc powder, agalmatolite powder, etc.), non-swellable clays, synthetic and diatomaceous silicas, montmorillonite, montromolite, bauxite, hydrated aluminas, perlite, sodium bicarbonate, wolves, vermiculites, limestone, natural and synthetic silicates such as calcium and magnesium silicates; titanium dioxides, hydroxides, silicates, carbonates and sulfates of calcium, magnesium, aluminum and titanium, sand; oxides of aluminium, titanium, magnesium, calcium and zinc; calcium and magnesium carbonates; as well as coal, silica, mica, Chinese clay, acid clay, attapulgite, diatomite, calcined alumina, their derivatives; chalk, e.g. Omya® chalk, fuller's earth, dolomite, kieselguhr, wood, profiles, talc, mirabilite, starch, white carbon, sericite, slaked lime, inorganic salts such as calcium carbonate, ammonium sulfate, sodium sulfate, potassium chloride, potassium and barium sulfates; their derivatives; organic solid carriers such as synthetic silicic acid, starch, cellulose, sulfur powder, urea powder, soybean meal, tobacco powder, flour, wood flour, vegetable powder, derivatives thereof; plastic carriers such as polyethylene, polypropylene, poly(vinylidene chloride), derivatives thereof; urea, hollow inorganic bodies, hollow plastic bodies, gypsum, fumed silica (white carbon) and their derivatives.

Commercially available silicates are the Aerosil, Sipemat brands such as Sipernat® 50S and CALFLO E, as well as Fa aerogels. Cabot, Kaolin 1777, Aluminosilicates, Wessalon® 50S. However, those skilled in the art will appreciate the possibility of using other solid supports without departing from the scope of the invention. These solid carriers are manufactured commercially and sold by various companies.

Mineral carriers include one or more kaolin minerals such as dikite, nakrite and halloysite; serpentines such as chrysotile, lizardite, antigorite and amesite; montmorillonite minerals such as sodium montmorillonite, calcium montmorillonite and magnesium montmorillonite; smectites such as saponite, hectorite, sauconite and hyderite; micas such as agalmatolite, muscovite, phengite, sericite and illite; silicas such as cristobalite and quartz; hydrated magnesium silicates such as attapulgite and sepiolite; calcium carbonates such as dolomite and fine calcium carbonate powder; sulfate minerals such as gypsum; tuffs, vermiculites, laponites, pumice, acid clays and activated clays or their derivatives. However, those skilled in the art will appreciate the possibility of using other mineral carriers without departing from the scope of the invention.

Vegetable carriers include one or more alcohols, cellulose, chaff, wheat flour, wood flour, starch, rice bran, wheat bran, and soy flour. Synthetic carriers include one or more wet-worked silicas, dry-worked silicas, calcined wet-worked silica products, surface-modified silicas, and modified starches (Pineflow manufactured by Matsutani Chemical Industry Co., Ltd.). However, those skilled in the art will appreciate the possibility of using other herbal carriers without departing from the scope of the invention.

Water soluble carriers include one or more soluble polymers such as methylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethylcellulose, sodium carboxymethylcellulose, propylene glycol alginate, polyvinylpyrrolidone, carboxyvinyl polymer, and casein.

- 33 040318 sodium; urea, ammonium sulfate, sucrose, sodium chloride, crystalline sodium sulfate, sodium carbonate, potassium carbonate, potassium pyrophosphate, sodium tripolyphosphate, maleic acid, fumaric acid, malic acid. However, those skilled in the art will appreciate the possibility of using other water soluble carriers without departing from the scope of the invention. According to an embodiment of the invention, the carrier is contained in an amount of from 0.1 to 98% m/m of the total composition. According to an embodiment of the invention, the carrier is contained in an amount of from 0.1 to 75% m/m of the total composition. According to an embodiment of the invention, the carrier is contained in an amount of from 0.1 to 50% m/m of the total composition. According to an embodiment of the invention, the carrier is contained in an amount of from 0.1 to 30% m/m of the total composition. According to an embodiment of the invention, the carrier is present in an amount of 0.1 to 20% m/m of the total composition. According to an embodiment of the invention, the carrier is present in an amount of 0.1 to 10% m/m of the total composition. According to an embodiment of the invention, the carrier is present in an amount of 0.1 to 5% m/m of the total composition.

According to an embodiment of the invention, fillers or diluents that may be used in the composition may include, among others, one or more of the following compounds: attapulgite, clay, kaolinite, montmorillonite, bauxite, hydrated aluminas, roasted aluminas, diatomite, chalk, fuller's earth, dolomite, diatomaceous earth, wood, profiles, talc, vermiculite, limestone, natural and synthetic silicates, titanium dioxide, calcium and magnesium silicates, synthetic and diatomaceous quartz, micas and Chinese clay, fertilizers such as, for example, ammonium, sodium, zinc, magnesium and potassium sulfates, sodium, sucrose, aluminum, calcium and zinc oxide, sodium benzoate, ammonium phosphate, ammonium nitrate and urea; natural vegetable products such as, for example, cereal flours, tree bark flour, wood flour, nutshell flour and cellulose powders; synthetic and polymeric materials, such as, for example, ground or crushed plastics and resins; mineral clays, bol, loess, talc, chalk, dolomite, limestone, lime, carbonates (calcium, magnesium), sodium acetate, alkali metal phosphates and alkaline earth phosphates, calcium phosphate, oxides (magnesium, aluminum, calcium and zinc), chlorides ( potassium, sodium), microcrystalline cellulose (e.g. Avicel™), polyvinylpyrrolidone, Wessalon® 50S precipitated silica, starch, kaolin, saccharides (glucose, fructose, lactose, mannitol, sorbitol, sucrose), dextrin, methylcellulose, hydroxyethylcellulose, powdered magnesium , coal, gypsum, calcium and barium sulfates, pyrophyllite, silicic acid, silicates and silica gels, water-soluble organic substances such as, for example, neopentyl glycol glycol, polyethylene glycol or their salts and derivatives. Diluents are water soluble or insoluble in water or mixtures of both. Water-soluble diluents include one or more salts, surfactants, carbohydrates, or derivatives thereof. However, those skilled in the art will appreciate the possibility of using other excipients or diluents without departing from the scope of the invention. These fillers or diluents are commercially produced and sold by various companies. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 90% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 75% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 50% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 30% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 20% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 10% m/m of the total composition. According to an embodiment of the invention, the filler or solvent is contained in an amount of from 0.1 to 5% m/m of the total composition. According to an embodiment of the invention, fillers are not necessarily used in the composition.

According to an embodiment of the invention, the water-degradable granular water-insoluble nutrient composition further comprises one or more biostimulants, pesticidal actives, water-soluble fertilizers, and macronutrients.

According to an embodiment of the invention, the biostimulants are selected from one or more microalgae or algae, enzymes, humic acid, fulvic acid, algae, bacteriospores, and microbes such as fungi, yeasts, and viruses. The biostimulants used are manufactured on an industrial scale and sold by various companies. However, those skilled in the art will appreciate the ability to use various biostimulants without departing from the scope of the invention.

According to an embodiment of the invention, the water-disintegrating granular composition of one or more algal actives also includes at least one of water-insoluble nutrients, biostimulants, pesticide actives, water-soluble fertilizers, and macronutrients.

According to an embodiment of the invention, the water-degradable granular composition of one or more pesticides also includes at least one of the water-insoluble

- 34 040318 nutrients, biostimulants, algal actives, water-soluble fertilizers and macronutrients.

According to an embodiment of the invention, bacterial spores include spores from one or more of the following bacteria:

Agrobacterium radiobacter, Azotobacter chrococcum, Azospirillum lippoferum, Azospirillum brasilense, Azospirillum lipoferum, Azospirillum irakense, Azospirillum halopraeferens, Bacillus amyloliquifaciens, Bacillus altitudinis Bradyrhizobium japonicum, Bradyrhizobium elkanii, Bacillus acidiceler, Bacillus acidicola, Bacillus acidiproducens, Bacillus aealius, Bacillus aerius, Bacillus aerophilus, Bacillus agaradhaerens Bacillus aidingemis Bacillus akibai Bacillus alcalophilm Bacillus altitudmis Bacillus algicola Bacillus azotoformans Bacillus badius Bacillus atyabhaltai Bacillus asahti Bacillus atrophaem Bacillus cohnii Bacillus coagulam Bacillus coahuilemls , Bacillus thuringenesis, Bacillus subtillus, Bacillus aizawai, Bacillus cereus, Bacillus circulans, B. circuians, Bacillus thermolactis, Bacillus kurstaki, Bacillus lentimorbus, Bacillus licheniformis, Bacillus megaterium, Bacillus mycoides, Bacillus mojavensis, Ba cillus mucillagenosus, Bukholderia cepacia, Bacillus horii, Bacillus humi, Bacillus polygoni, Bacillus popillae, Bacillus pumilus, Bacillus sphaericus, Bacillus neahonii, Bacillus mizhmtemis, Bacillus niabensis, Bacillus macirti, Bacillus polymyxa, Bacillus sonoremisterra, Bacillus sporothenrnxlura , Bacillus taeamis, Bacillus tequilemis, Bacillus fhermamarcticm, Bacillus thermoamyhvorans, Bacillus thermacloacae, Bacillus thermolactis, Bacillus ihioparans, Pesudomonas fluorescens, Pseudomonas solanacearum, Pseudomonas syringae, Pseudomonas cepacia, Agrobacterium radiobacter, Azotobacter chroococcum Azospirillum lippoferum, Peaenibacillus azotofixans, Peaenibacillus durum, Pasteuria penetrans , Rhizobium leguminosarum, Rhizobium tropici, Bukholderia cepacia, Streptomyces lydicus, Thiobacillus thiooxidans and Thiobacillus novellus.

According to an embodiment of the invention, bacterial spores are present in a concentration range from 0.1 to 50% by weight of the total composition. According to an embodiment of the invention, bacterial spores are present in a concentration range from 0.1 to 40% by weight of the total composition. According to an embodiment of the invention, bacterial spores are present in a concentration range from 0.1 to 30% by weight of the total composition. According to an embodiment of the invention, bacterial spores are present in a concentration range of 0.1 to 20% by weight of the total composition. According to an embodiment of the invention, bacterial spores are present in a concentration range from 0.1 to 10% by weight of the total composition. According to an embodiment of the invention, bacterial spores are present in a concentration range of 0.1 to 5% by weight of the total composition. However, those skilled in the art will appreciate the possibility of using other bacterial spores without departing from the scope of the invention. These bacterial spores and microbes are commercially grown and marketed by various companies.

According to an embodiment of the invention, the pesticidal actives contained in the water-degradable granular composition of water-insoluble nutrients or algal actives include antifoulants, attractants, insecticides, fungicides, herbicides, nematocides, pheromones, defoliants, acaricides, plant growth regulators, algicides , antifeedants, avicides, bactericides, bird repellents, biopesticides, biocides, chemosterilizers, plant protection products, insect attractants, insect repellents, insect growth regulators, mammal repellents, male destabilizers, disinfectants, molluscicides, antimicrobial agents , miticides, ovicides, fumigants, plant activators, rodenticides, synergists, virucides, repellents, microbial pesticides, incorporated plant protectants, various other pesticidal actives or salts, derivatives and combinations thereof. According to an embodiment of the invention, the pesticidal active is present in a concentration range from 0.1 to 99% by weight of the total composition. According to an embodiment of the invention, the pesticidal active is present in

- 35 040318 concentration range from 0.1 to 80% by weight of the total composition. According to an embodiment of the invention, the pesticidal active is present in a concentration range of 0.1 to 60% by weight of the total composition. According to an embodiment of the invention, the pesticidal active is present in a concentration range of 0.1 to 40% by weight of the total composition. According to an embodiment of the invention, the pesticidal active is present in a concentration range of 0.1 to 20% by weight of the total composition. According to an embodiment of the invention, the pesticidal active is present in a concentration range of 0.1 to 5% by weight of the total composition.

In another embodiment, the macronutrients are selected from carbohydrates or fats or proteins or fiber or antioxidants and combinations thereof. However, those skilled in the art will appreciate the possibility of using other macronutrients without departing from the scope of the invention. These macronutrients are manufactured commercially and sold by various companies.

In another embodiment, the water soluble fertilizers are selected from urea, sulfur based fertilizers, phosphate fertilizers such as MAP, DAP, potash fertilizers, nitrate fertilizers, ternary fertilizers or derivatives thereof, salts, complexes and combinations. According to an embodiment of the invention, water-soluble fertilizers contain one or more of the group of compounds: iron sulfate, magnesium sulfate, manganese sulfate, copper sulfate, sodium molybdate, zinc sulfate, boric acid or their derivatives, salts, complexes and mixtures. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 85% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 75% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 60% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 45% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 25% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 10% by weight of the total composition. According to an embodiment of the invention, the water soluble fertilizer is present in a concentration range of 0.1 to 5% by weight of the total composition. However, those skilled in the art will appreciate the possibility of using other water soluble fertilizers without departing from the scope of the invention.

According to an embodiment of the invention, the water-insoluble nutrients included in the water-disintegrating granular composition of pesticidal actives or algal actives contain water-insoluble fertilizers or micronutrients. According to an embodiment of the invention, the water-insoluble nutrient comprises a mixture of one or more water-insoluble fertilizers and one or more micronutrients, or salts or derivatives or complexes thereof. According to an embodiment of the invention, the water-insoluble fertilizer is either a single nutrient fertilizer, or a multi-component fertilizer, or a two-component fertilizer, or a combined fertilizer, or an organic fertilizer, derivatives or combinations thereof. However, those skilled in the art will appreciate the possibility of using other fertilizers known in the art without departing from the scope of the invention. In an embodiment, the water-insoluble fertilizer is one or more of nitrate, phosphate, and potash fertilizers, or sulfate fertilizers such as elemental sulfur.

According to an embodiment of the invention, the water-insoluble micronutrient nutrient includes minerals such as boron, calcium, chlorine, chromium, cobalt, copper, fluorine, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, silicon, sodium, zinc, or salts or derivatives of these minerals.

According to another embodiment, the invention also relates to a process for the preparation of a water-degradable granular composition of water-insoluble nutrients or pesticidal actives or algae. The water-disintegrating granular composition is produced by various methods such as drying, spraying, granulating, agglomerating, extrusion or extrusion followed by spheronization, etc.

According to an embodiment of the invention, the process for preparing a water-disintegrable granular composition comprises grinding a mixture of either a water-insoluble nutrient or pesticidal actives or algae, water, and at least one agrochemically acceptable excipient to form a wet mixture, for example in the form of a suspension. The resulting wet mixture is then dried to obtain a fine powder or a coarse granule or microgranule, for example in a spray dryer or any suitable drying equipment. Powder or fine granules or microgranules are additionally subjected to agglomeration in a granulator. The granulator may include various devices such as a disc or trough, screw granulator, spheronizer, or combinations thereof.

The agglomeration process needs to be controlled in terms of feed rate and sequence.

- 36 040318 the accuracy of the granulation equipment used in order to obtain granules with the required properties. For example, once material has been obtained from a spray dryer, it may be further agglomerated in a fluidized bed dryer, after which the material is fed to a screw granulator. Alternatively, the material from the spray dryer is further dried in a fluidized bed dryer and then fed via a screw or belt conveyor to a trough granulator. Tray, disc or screw granulators are produced by various companies, such as Feeco. At the stage of granulation (when trough or screw granulation) you can add water or an aqueous suspension containing a binder. To obtain soft granules with low bulk density, the speed of the screw granulator can be controlled. As a rule, the size of the granules coming out of the screw granulator is about 1 mm.

The speed of the tray granulator can be adjusted from 5 to 100 rpm. As a rule, the speed is maintained in the range from 5 to 60 rpm. To increase the size of the granules and subject them to greater granulation, the angle of the pan granulator can be adjusted. Generally, using the pan granulator at lower speeds results in rough, loosely compacted, smaller granules. Processing the composition in a trough granulator at higher speeds results in denser, almost spherical granules. The resulting large granules with the desired size, abrasion resistance, hardness and bulk density can be further dried in a fluid bed dryer. The temperature can be maintained in the range of 35 to 100° C. depending on the composition in the fluidized bed dryer. The granules obtained from the granulator can be dried in the open air or blown with air to remove any residual moisture, if any. However, those skilled in the art will appreciate the ability to change the process or process parameters without departing from the scope of this invention. The obtained granular composition capable of disintegrating in water has a granule size of 0.1 to 6 mm, preferably 1 to 5 mm, and a particle size of 0.1 to 50 µm. The resulting granules capable of disintegrating in water have a hardness of at least 1 N and a bulk density of less than 1.5 g/ml.

According to another embodiment of the invention, it relates to the use of a water-degradable granular composition containing a water-insoluble nutrient or algae, as either a fertilizer composition, or a nutritional composition, or a plant stabilizer, ameliorants, and yield enhancer.

According to another embodiment, the invention relates to the use of a water-disintegrating granular composition containing a pesticidal active as a plant protection composition.

In another embodiment, the invention also relates to a method for improving plant health. The method comprises treating at least one of a plant, plant propagation material, seed, seedling, or surrounding soil with a water-disintegrating granular composition containing at least one water-insoluble nutrient or at least one algae in a range of concentrations from 5 to 90% by weight and at least one agrochemically acceptable excipient; while the granules are presented in the size range from 0.1 to 6 mm and are characterized by a bulk density of less than 1.5 g/ml and a hardness of at least 1 N.

According to an embodiment, the invention also relates to a method for strengthening crops or plants. The method comprises applying a water-disintegrating granular composition containing one or more water-insoluble nutrients or at least one algae in a concentration range of at least 0.1 to 95% by weight and at least one agrochemically acceptable excipient; wherein the composition is presented in the size range from 0.1 to 6 mm, and the particles are presented in the size range from 0.1 to 50 μm; and wherein the granules are characterized by a bulk density of less than 1.5 g/ml and a hardness of at least 1 N, on at least one of the plants, plant foliage, plant propagation material, plant growth sites, seeds, seedlings, soil and environment agricultural culture.

According to an embodiment, the invention also relates to a plant protection method comprising applying a water-disintegrating granular composition containing one or more pesticidal actives in a concentration range of 0.1 to 95% by weight; and at least one agrochemically acceptable excipient; has granules in size from 0.1 to 6 mm, particle size from 0.1 to 50 microns; and in which the granules have a bulk density of less than 1.5 g/ml and a hardness of at least 1 N, or per plant, or plant leaves, or plant propagation material, or per plant locus, or seeds, seedlings, soil and cultural environment.

The composition is applied in various ways. Soil application methods include any suitable method to ensure that the composition penetrates the soil, such as using a mechanical applicator or by hand, brooding tray application, furrow application, soil moistening system, soil injection or soil application, etc. .

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The frequency of application or dosage of the composition depends on the type of application, the type of crops or those or other active substances of the composition, but in such a way that an effective amount of the agrochemical active substance provides the desired effect (for example, nutrient uptake, plant vigor, crop yield).

Typically, a granular composition for agricultural use does not release a nutrient until it has been applied to the desired target. Alternatively, the composition may be designed to release the agrochemical nutrient instantaneously and simultaneously slowly over a period of time.

A. Examples of receipt.

The examples below illustrate the basic methodology and versatility of the composition of the invention.

I. Water-disintegrating granules containing various nutrients and pesticides.

Table 1

Components Sample I Sample II Sample III Sample IV Sample V iron oxide 6 65 80 90 95 Mancozeb - 10 - - - Thiamethoxam - - 8 - - Naphthalenesulfonate condensate 22 10 5 9.8 5 Sodium lignosulfonate 20 10 5 - - Polyvinylpyrrolidone - 0.1 OD 0.2 - Kaolin 52 4.9 1.9 - - Total 100 100 100 100 100

Sample I was prepared by mixing 6 parts of iron oxide, 22 parts of naphthalenesulfonate condensate and 20 parts of sodium lignosulfonate to form a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting slurry was subjected to wet grinding in appropriate wet grinding equipment. The resulting wet milled slurry was spray dried at an inlet temperature of less than 180° C. and an outlet temperature of less than 85° C. to obtain a granular powder with a moisture content of less than 10%. The spray-dried powder thus obtained was subjected to granulation in a fluid bed dryer, followed by granulation in a screw and tray granulator. The speed of the tray granulator was maintained at about 35 rpm to obtain the granular composition of sample 1 for agricultural use. Water was added during granulation. After that, the resulting granules were further dried in a fluid bed dryer to eliminate residual moisture at a temperature of about 70°C. The composition had the following particle size distribution: D10 less than 0.7 microns; D50 less than 4 µm and D90 less than 10 µm. The average grain size of the sample was 3.8 mm. The bulk density of the composition was 1.2 g/ml, the abrasion resistance was 95% and the hardness was 45 N. The retention value on a wet sieve with a pore size of 75 μm was 2.3%

Samples II-V were obtained in accordance with the process of obtaining sample 1, while the samples included iron oxide and other components in the concentrations indicated in table. 1.

II. Able to disintegrate in water granules containing sulfur from 5 to 95% m/m.

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table 2

Components Sample I Sample II Sample III Sample IV Sample V Sample VI Sulfur 5 40 55 - 90 95 Azoxystrobin - - - 13.5 - - zinc oxide - - 9.5 thirty - - Humic acid - - 9.5 - - - Sodium salt of sulfonic alkyl carboxylate 22 - 12.5 25 4 3 Ether of polyoxyethylene and alkylphenyl - 8 - - - - Maltodextrin 9 - - - - - Starch 2 11.5 - - 4 2 willow 0.2 - 0.1 - - 0 China clay 61.8 40 8.4 31.5 2 0 Spirulina - - 5 - - - Total 100 100 100 100 100 100

Sample I was prepared by mixing 5 parts of sulfur active, 22 parts of sulfonated alkyl carboxylate sodium salt, 2 parts of starch, 9 parts of maltodextrin and 61.8 parts of china clay to form a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting slurry was subjected to wet grinding in suitable wet grinding equipment. The resulting wet milled slurry was spray dried at an inlet temperature of less than 140° C. and an outlet temperature of less than 55° C. to obtain microgranules or granular powder with a moisture content of less than 10%. The spray-dried powder thus obtained was subjected to granulation in a tray granulator to obtain a granular composition of sample 1 for agricultural use. 0.2 parts of polyvinyl alcohol was added during granulation. The composition had the following particle size distribution: D10 less than 0.7 microns; D50 less than 4 µm and D90 less than 10 µm. The average granule size of the sample was 2.8 mm, the bulk density was 1.1 g/ml, and the hardness was 45 N.

Samples II, V and VI were obtained in accordance with the process of obtaining sample 1, while the samples included sulfuric active substance and other components in the concentrations indicated in table. 1.

Samples III and IV were also obtained in accordance with the sample preparation process 1, where the samples respectively included sulfur plus humic acid and zinc oxide plus azoxystrobin with other components in various concentrations, as indicated in table. 1.

III. Water-degradable granules containing sulfur in an amount of 50-85% m/m and iron oxide/zinc oxide in an amount of 10-30% m/m.

Table 3

Components Sample I Sample II Sample III Sample IV Pattern V Weight % Sulfur 50 55 70 80 85 iron oxide thirty 3 - - 10 zinc oxide - 9.5 15 5 - Baccillus sp. - - - 5 - Phenol formaldehyde condensate 10 15 15 9.8 3.1 Sodium lignosulfonate 5 8 - - 1.9 Polyvinylpyrrolidone 0 0.1 - 0.2 - Kaolin 5 9.4 0 0 0 Total 100 100 100 100 100

Sample I was prepared by mixing 50 parts of sulfur active, 30 parts of iron oxide, 10 parts of phenol-formaldehyde condensate and 5 parts of sodium lignosulfonate to form a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting suspension was subjected to wet grinding in appropriate equipment for

-39040318 wet grinding. The resulting wet ground slurry was spray dried at an inlet temperature of less than 140° C. and an outlet temperature of about 80° C. to obtain microgranules with a moisture content of less than 10%. The spray-dried powder thus obtained was subjected to granulation in a fluid bed dryer and a granulator pan to obtain a water-disintegrating granular composition of Sample 1. Water was added during granulation. The composition had the following particle size distribution: D10 less than 0.7 microns; D50 less than 5 µm and D90 less than 20 µm. The average granule size of the composition was 3 mm, bulk density - 1.15 g/ml, hardness - 24 N and abrasion resistance - 87%. The retention value on a wet sieve with a pore size of 75 µm was 1.8%

Samples II-V were obtained in accordance with the process for obtaining sample I, while the samples included sulfuric active substance and other components in the concentrations indicated in table. 3.

IV. Water-disintegrating granules containing iron sulphate, copper sulphate, manganese oxide, boric acid, zinc oxide and sulfur.

Table 4

Components Sample I Sample II Sample III Weight % manganese oxide 3 - 8.2 zinc oxide 8.2 15.5 6.5 Boric acid 8.8 7.5 8.5 Sulfur 50 - 35 ferrous sulfate AND 15 8.5 copper sulfate 4 - 4 Sodium molybdate - - 0.5 Maltodextrin 3 10.2 - Sodium lignosulfonate 10.6 33.2 10.6 Polyvinylpyrrolidone 0 0.2 - Kaolin 1.4 18.4 18.2 Total 100 100 100

Sample I was prepared by mixing 3 parts of manganese oxide, 8.2 parts of zinc oxide, 8.8 parts of boric acid, 50 parts of sulfur, 11 parts of ferrous sulfate, 4 parts of copper sulfate and 10.6 parts of sodium lignosulfonate, 3 parts of maltodextrin, 1 .4 parts of kaolin to obtain a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting slurry was subjected to wet grinding in suitable wet grinding equipment. The resulting wet milled slurry was spray dried at an inlet temperature of less than 185° C. and an outlet temperature of less than 80° C. to obtain microgranules with a moisture content of less than 10%. The microgranules or powder thus obtained were subjected to granulation in a fluid bed dryer and a tray granulator to obtain a water-disintegrating granular composition of sample 1. Water was added during granulation. The composition had the following particle size distribution: D10 less than 0.7 microns; D50 less than 8 µm and D90 less than 20 µm. The average granule size of the composition was 1 mm, bulk density - 1.15 g/ml, hardness - 10 N and abrasion resistance - 87%. The retention value on a wet sieve with a pore size of 75 μm was 1.8%.

Samples were obtained in accordance with the process of obtaining sample 1, while the samples included the components at the concentrations indicated in table. 4.

V. Water-disintegrating granules containing algae.

Table 5

Components Sample I Sample II Sample III Sample IV Sample V Sample VI Spirulina Sp. - 40 - - 90 Chlorella vulgaris. 36.85 - 2 65- 80% - 1,2- 0.15 - - 0.85 - -

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benzisothiazoline-3 he 1,2-dibromo-2,4dicyanobutane - - - - 2.1 0.5 Maltodextrin 14.10 - - 11.7 - 1.1 Starch 8.90 12.5 35 - 13.5 - Naphthalenesulfonate Condensate 12 18 5 - 4.4 2.1 Sodium lignosulfonate 4.2 7.7 14 10 - - polyvinyl alcohol - 0.2 - 0.1 - 0.2 Kaolin 23.8 21.6 - 12.35 - 6.1 Total 100 100 - 100 100 100

Sample I was prepared by mixing 36.85 parts of Chlorella vulgaris dry biomass, 0.15 parts of 1,2-benzisothiazolin-3-one, 4.10 parts of maltodextrin, 8.90 parts of starch, 12 parts of naphthalenesulfonate condensate, 4.2 parts of lignosulfonate sodium and 23.8 parts of kaolin to obtain a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting slurry was subjected to wet grinding in appropriate wet grinding equipment. The resulting wet ground slurry was spray dried at an inlet temperature of less than 160° C. and an outlet temperature of less than 75° C. to obtain a granular powder with a moisture content of less than 10%. The spray-dried powder thus obtained was subjected to granulation to obtain a granular composition of sample 1 for agricultural use. The composition had the following particle size distribution: D10 less than 0.7 microns; D50 less than 4 µm and D90 less than 10 µm. The retention value on a wet sieve with a pore size of 75 μm was 2.8%.

Samples II-VI were obtained in accordance with the sample preparation process 1, where the samples included Chlorella Sp. and Spirulina Sp. as an active substance and other components in the concentrations indicated in the table above.

VI. Water-disintegrating granules containing thiamethoxam or azoxystrobin from 0.1 to 95% m/m.

Table 6

Components Sample I Sample II Sample III Sample IV Thiamethoxam - 40 0.9 - Azoxystrobin 23 12 - 70 zinc oxide 9.8 - 40 Urea - 5 20 7 Ether of polyoxyethylene and alkylphenyl 5.5 - 2 - Sodium salt of lignin sulfonate 19.5 22 20 - starch - 2 1 9.2 Polyvinylpyrrolidone 0.5 - 0.2 - Clay 41.7 19 15.9 13.8 Total 100 100 100 100

Sample I was prepared by mixing 23 parts of azoxystrobin active, 9.8 parts of zinc oxide, 5.5 parts of polyoxyethylene alkylphenyl ether, 19.5 parts of sodium lignin sulfonate and 41.7 parts of clay to form a mixture. The resulting mixture was crushed to obtain a powder with a particle size of less than 50 μm. The powder was mixed with water in appropriate equipment to form a suspension of solids from 35 to 75%.

The resulting slurry was subjected to wet grinding in appropriate wet grinding equipment. The resulting wet milled slurry was spray dried at an inlet temperature of less than 170° C. and an outlet temperature of less than 85° C. to obtain a granular powder with a moisture content of less than 10%. The spray-dried powder thus obtained was subjected to granulation in a tray granulator to obtain a granular composition of sample 1 for agricultural use. 0.5 parts of polyvinylpyrrolidone was added during granulation. The composition had the following particle size distribution: D10 less than 0.9 µm; D50 less than 6 µm and D90 less than 15 µm. The average granule size of the sample was 3.8 mm, bulk density -1.2 g/ml, hardness - 48 N. The retention value of the composition on a wet sieve with a pore size of 75 μm was 2.5%.

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Samples II-IV were obtained in accordance with the process of obtaining sample 1, while the samples included active substances and other components in various concentrations indicated in the table above.

Comparison of the physical properties of water-degradable granules of water-insoluble nutrients.

Table 7

Sample Composition Components Bulk density (g/ml) Hardness (newton) Disintegration time (min) Abrasion resistance Granule size (mm) Average particle size (µm) (D50) Dispersion (%) Suspension Wet sieve retention at 75 µm(%) True density noet b (g / cm 3) C1 90% Sulfur Granules for Agricultural Applications According to an Embodiment of the Invention 0.92 40N 10 min 98% 1.04.00 3.37 20.4% 39.8% ZD 1.95 C2 Water-dispersible sulfur granules 90% according to an embodiment of WO20080844 95 0.84 No data available No data 49% OD-2.5 2.183 82% 85% 1.3 1.98 NW Bentonite pellets sulfur 90% 1.05 32 N 25 min 99.8% 2.0-3.0 130 Not dispersible Zero No data available >90% 2 C4 Water-degradable sulfur granules 70% + zinc oxide 15% according to an embodiment of this invention 1D 51H 5 minutes 99% 1.54.00 4.49 46.1% 20.9% 1.5 1.96 C5 Sulfur granules 70% + zinc oxide 15% as described in WO20121317 0.89 No data 0 <1 min 48% OD-2.5 4.183 9 78% 74% 2 1.87

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02 C6 Water-degradable granules of MAP 85% and sulfur 10% according to an embodiment of the present invention 1.09 38 N 30 min 98% 1.54.00 3.49 20.4% 39.8% 3.6 2.2 C7 Pellets MAP 85% and sulfur 10% according to embodiment WO20161836 85 1.8 34 N 48 min 87% OD-2.5 114.4 Not dispersible No data available Not suspended 10.2 2.9 C8 Water-degradable sulfur granules 55% + zinc oxide 9.5% + iron oxide 3% obtained according to an embodiment of this invention 1.01 34 N 35 min 98% 1.54.00 4.45 46.1% 84.2% 2.8 1.97 C9 Water-dispersible sulfur granules 55% + zinc oxide 9.5% + iron oxide 3% as described in WO20121317 02 0.89 No data available No data 43% OD-2.5 4.253 59.4% 67.9% 1.8 1.95 CIO Water-degradable sulfur granules 55% + zinc oxide 9.5% + iron oxide 3% + silicon dioxide 2.5% according to an embodiment of this invention 1.129 24.1 N 22 min 98% 1.54.00 3.47 31% 58.8% 3.3 2D Cll Water-dispersible sulfur granules 55% + oxide 0.82 No data No data 48% OD-2.5 4.253 58.7% 66.56% 1.3 1.98

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zinc 9.5% + iron oxide 3% + silicon dioxide 2.5% as described V WO2012131702 T C12 Water-degradable sulfur granules 55% + tumic acid 9.5% + zinc oxide 9.5% + Spirulina 5% according to an embodiment of the present invention 0.89 1.5 8min 74% 3.5-6.00 25.5 20% 32% 6.3 1.87 C13 Water-degradable granules of sulfur 50% + iron oxide 30% according to an embodiment of the present invention 1.09 68 N 130 min 96.9% 1.54.00 5.49 48.1% 15% 1.5 2.15 C14 Water-degradable granules zinc oxide 15.5%+boric acid 7.5%+ferrous sulfate 15% according to an embodiment of the present invention 1.16 38.1 N 26 min 98% 2.5-5.00 12 32% 44% 3.1 2.4 C15 Liquid suspension zinc oxide 15.5% + boric acid 7.5% + iron sulfate 15% No data available No data No data No data P,2 67.7% 71.65% 1.75 C16 Sulfozinc (bentonite pellets sulfur 65% + zinc oxide 18%) 1.02 24 N 22 min 97% 2.0-3.0 135 7.4% No data available Not suspended No data Very high, over 90% 2.9

From Table. 7 it can be seen that sample C1 - 90% water-dispersible sulfur pellets - obtained according to an embodiment of the present invention, has a hardness of 40 N compared to sample C2 90% water-dispersible sulfur pellets - obtained as described in WO 2008084495, not has a hardness and shows resistance to abrasion of only 49%, as a rule, when the grain size is from 0.5 to 2.5 mm.

50 g of each composition C1, C2 and C3 was added to test tubes with 500 ml of water and left without stirring. In FIG. 5 shows a comparison of three compositions: C1 (tube B) - 90% sulfur granular composition according to an embodiment of the present invention, C2 (tube C) - 90% water-dispersible sulfur granules according to WO 2008084495 and C3 (tube A) - sulphate granules. bentonite. As can be seen, C2 completely and instantly disperses upon contact with water.

In FIG. 6-11 demonstrate the slow release and dispersion of the composition of the present invention C1 over 15 minutes, 30 minutes, 1 hour, 2 hours, 4 hours and 24 hours. nutrient, and the contents of the tube are a nearly clear solution even after 24 hours.

In addition, it can be noted that although sample C3 with 90% sulfur bentonite pellets has the same hardness and abrasion resistance as sample C1 with 90% sulfur bentonite pellets, these prior art pellets have a very high particle size, very poor dispersion and zero suspension, which, as can be seen from the tables below, leads to poor performance in the field. While these prior art pellets exhibit relatively low disintegration times, they disintegrate only by mechanical agitation. As can be seen from FIG. 5-11, if they are not stirred, these bentonite granules, when added to a test tube with water, do not disintegrate for several hours or even days. This problem is much more serious when such compositions are applied to the soil. These prior art compositions are environmentally damaging because soils may not have sufficient moisture and these prior art pellets do not self-degrade and disperse properly.

In addition, compositions C1, C4, C6, C8, C10, C12, C13, C14, C15 according to embodiments of the present invention exhibit excellent hardness compared to prior art water-disintegrating granular forms having no hardness. The present compositions are also dispersible and slowly disintegrate over a period of time, in contrast to water-dispersible granular forms which disperse instantly.

It can also be seen that while sample C16 with sulfozinc (65% sulfur bentonite pellets + 18% zinc oxide) has similar hardness and abrasion resistance as sample C1 with 70% sulfur degradable grains + 15% zinc oxide, these pellets have very poor dispersion and zero suspension, which can be explained by their poor performance, as can be seen from the table below.

Sample C6, containing the water-degradable MAP granules 85% (monoammonium phosphate) and sulfur 10% according to an embodiment of the present invention, also shows a bulk density of 1.09 g/ml compared to sample C7 prepared according to WO 2016183685 which also contains MAP 85% and sulfur 10%, however in the form of pellets with a bulk density of 1.8 g/ml. The composition of the prior art (sample C7) is formed in the process of extrusion and pressing in the granulator Kal. Sample C7 also exhibits a longer disintegration time and substantially zero dispersion and suspension compared to sample C6 according to embodiments of the present invention.

Field studies

The influence of different types of processing on the growth of peanuts.

Trials were carried out in Kanpur (Idar), Sabarkanta District, India, to evaluate various formulations for the treatment of GG-24 peanuts. The area of the land plot was 228 m ² . All recommended agricultural practices were followed. The compositions were applied by manual spreading. Plant height, number of branches/plant, number of pods/plant, yield were monitored before application of the compositions and 30, 60 and 90 days after. The final oil content was measured and recorded as a percentage. Plant height was measured on 10 selected plants from each plot for each replication. The number of branches was measured in 10 selected plants from each plot for each repetition. The number of pods was determined in 10 selected plants from each plot for each repetition. The yield was measured from each plot and calculated in t/ha. Observations also included registration of sulfur and zinc content in plants 30, 60 and 90 days after application. The observation was documented as shown below.

- 45 040318

Table 8

Treatment number Composition Components Dose kg/ acre plant height (cm) Number of branches / plant Number of pods / plant Yield (kg/ha) Straw yield (kg/ha) 30 dp p 60 dp p 90 dp p 30 dpo 60 Dpp 90 Dpp 60 DPP 90 DPP At the time of harvest 1 Water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of the present invention) 4 32.5 37.5 39.2 27.30 33.60 35.5 21.10 22.30 3016.12 2.091 2 Water dispersible granules of sulfur 70% + zinc oxide 15% as described in WO201213170 2 4 27.5 34.40 34.80 18.60 29.40 31.30 18.70 20.60 2833.33 1.943 3 Sulfozinc (bentonite pellets sulfur 65% + zinc oxide 18%) 8 24.3 29.1 29.5 14.2 25.2 26.5 15.1 17.1 2632.33 1.611 4 Sulfur bentonite marshmallows 90%+ZnSO4 33% 6+6 18.1 30.20 34.30 14.20 28.40 27.90 19.20 19.10 2146.67 1.301 5 Raw control - 11.6 22.70 23.1 9.20 19.7 21.5 15.10 15.20 1706.67 1.005

Available content of sulfur and zinc in the plant

Table 8A

Serial number Treatment Dose (kg/acre) plant specimen Sulfur content (%) Zinc content (ppm) thirty Dpp 60 Dpp 90 Dpp thirty Dpp 60 Dpp 90 Dpp 1 Water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of the present invention) 4 0.62 0.72 0.65 32.23 38.17 52.85 2 Water-dispersible granules of sulfur 70% + zinc oxide 15% as described in WO2012131702 4 0.51 0.60 0.56 26.38 33.83 46.33 3 Bentonite marshmallows sulfur 90% + ZnSO4 33% 10+10 0.43 0.51 0.49 21.72 32.83 42.50 4. Sulfozinc (sulfur pellets 65% + zinc oxide 18%) 8 0.37 0.48 0.39 23.23 29.27 43.35 5 Control - 0.32 0.38 0.29 21.62 27.17 42.33

From the above table, it is clear that treatment 1 with water-degradable granules of sulfur 70% + zinc oxide 15%, obtained according to an embodiment of the present invention, not only showed an increase in plant height after 30, 60 and 90 days after application, but

- 46 040318 also an increase in the number of branches and gynophora per plant compared to treatment with 2 water-dispersible granules with a sulfur content of 70% + zinc oxide 15%, obtained as described in

WO 2012131702. It was noted that the height of plants with treatment 1 was 12.64% higher and the number of branches per plant was 13.4% higher than with treatment 2 on the 90th day after application, even with the same the amount of sulfur and zinc oxide used in both treatments.

From the above table, it is clear that treatment of 1 with water-degradable sulfur granules 70% + 15% zinc oxide according to an embodiment of the present invention demonstrated an increase in the number of peanut pods per plant by 12.8 and 8%, respectively, after 60 days and 90 days after application compared to treatment 2 with water-dispersible granules of sulfur 70% + zinc oxide 15% as described in WO 2012131702. Treatment 1 also shows an increase in overall plant yield and straw yield compared to treatment 2. Surprisingly, application of treatment 1 actually shows a 6.45% increase in plant yield and a 7.6% increase in straw yield at harvest compared to treatment 2. This surprising result can be explained by the fact that peanuts require zinc for 75 days after sowing, and the composition of this invention (Treatment 1) provided sulfur and zinc instantly and continuously to the plant, resulting in better pod development and higher yields. ness.

It is noted that treatment 2 with a water-dispersible granular composition of sulfur and zinc, as described in WO 2012131702, provides only an immediate availability of active substances, while improved branching, the number of pods per plant, or a significant improvement in yield due to the water-disintegrable granular composition of treatment 1, according to an embodiment of the present invention, due to the instantaneous and sustainable availability of nutrients throughout the entire life cycle of the crop. Thus, the unexpected results are attributed to the improved hardness of the water-disintegrating granular composition of the present invention, along with proper dispersibility and suspension, which provides an immediate and sustained release of nutrients from Treatment Composition 1 (Table 7 Sample C4) compared to Treatment Composition 3 (Sample C5 table 7).

In addition, it was found that the increase in the number of peanut pods per plant and overall yield when using treatment composition 1 containing water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of this invention) was surprisingly higher, even when treatment composition 1 was applied at a dose of only 4 kg per 1 acre, compared with treatment composition 3 with sulphozinc (65% sulfur bentonite pellets + zinc oxide 18%), which was applied at a dose of 8 kg per 1 acre. It can be said that the particle size, low wet sieve retention, and fineness of the water-disintegrating granular treatment composition 1 (Table 7 Sample C4) compared to Treatment 2 composition (Table 7 Sample C5) accounted for this surprising result.

In addition, it was found that the increase in the number of peanut pods per plant and overall yield when using treatment composition 1 containing water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of this invention) was unexpectedly higher, even when treatment composition 1 was applied at a dose of only 4 kg per acre, compared with treatment composition 5 containing a composition of bentonite granules of sulfur 90% + ZnSO ₄ 33%, where bentonite granules of sulfur 90% were used at a dose of 6 kg/acre, and ZnSO ₄ 33% - at a dose of 6 kg/acre.

From the above table, it is clear that treatment 1 with water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of the present invention) shows a significantly higher content of zinc and sulfur in peanuts 30, 60 and 90 days after application compared with treatment with 2 water-dispersible granules of sulfur 70% + zinc oxide 15% prepared as described in WO 2012131702. Application of treatment 1 actually shows an increase in sulfur content of 16% and zinc content of 14% 90 days after application compared to treatment 2. Unexpected results are also observed when treatment composition 2 contains the same concentration of sulfur and zinc, and this difference is due to the slow but continuous supply of nutrients to the culture from the composition of this invention at the appropriate stages of development. The unexpected results are also due to a more improved form of the present invention, which is characterized in that the water-disintegrating granules exhibit better abrasion resistance and hardness compared to the water-dispersible granules of treatment 2, which easily crumble to fine dust particles after packaging and transportation, as seen from Fig. 2, which leads to their lower efficiency. In addition, it was once again noted that the treatment of 2 water-dispersible granular composition of sulfur 70% + zinc oxide 15%, as described in WO 2012131702, provides instant absorption of active substances, as a result of which nutrients are not available at later stages of cultivation, while the water-disintegrating granular composition (treatment 1) of the present invention provides instant and sustained nutrient availability throughout the life cycle of the crop, thereby showing excellent results compared to prior art compositions.

In addition, it was noted that the uptake of sulfur and zinc by plants is higher when

- 47 040318 application of treatment composition 1 compared to treatment composition 4 containing sulfozinc (bentonite granules of sulfur 65% + zinc oxide 18%) when treatment 4 was applied at higher doses. The improved particle size and increased suspension and fineness of the water-disintegrating granular composition of Treatment 1 (Table 7 Sample C4) compared to Treatment 4 (Table 7 Sample C16) results in better sulfur and zinc uptake in Treatment 1 as seen in the table above.

Effects of different treatments on peanut yield and yield parameters

Table 8B

Serial number Processing Dose kg/acre plant height (cm) Number of branches / plant Number of pods / plant Total plant weight (kg/sq.m) Yield (kg/ha) Straw yield (kg/ha) thirty DP p 60 TO p 90 TO p 30 dp p 60 DP p 90 DP p 60 DP p 90 TO p At the time of harvest 1 Water-degradable 90% sulfur granules according to an embodiment of the present invention 3 21.7 36.2 38.8 15.5 32.1 33.2 20.3 21.20 1.669 2598.33 140.3 2 Water-dispersible sulfur granules 90% according to embodiment WO200808449 5 3 17.4 32.60 34.00 13.60 28.80 30.60 18.80 19.80 1.471 2320.00 1.239 3 Bentonite pastilles sulfur 90% 8 15.6 30.2 33.6 11.7 29.3 28.4 16.90 18.20 1,350 2136.67 1.146 4 Raw control - 11.6 22.70 23.1 9.20 19.7 21.5 15.10 15.20 1.277 1706.67 1.005

Table 8C

Serial number Treatment Dose (kg/acre) SAMPLE PLANT Sulfur content (%) 30 DNP 60 Dpp 90 Dpp 1 Water-Degradable Sulfur Granules 90% Produced According to an Embodiment of the Invention 3 0.45 0.57 0.44 2 Water-dispersible sulfur granules 90%, obtained according to the embodiment of WO2008084495 3 0.40 0.50 0.40 3. Bentonite pastilles sulfur 90% 8 0.36 0.42 0.36 4 Control - 0.32 0.38 0.29

It can be seen from the above table that the treatment of 1 with water-degradable 90% sulfur pellets according to an embodiment of the present invention demonstrates an increase in plant height at 30, 60 and 90 days after application, an increase in the number of branches and gynophores per plant, as well as a significant increase in the number peanut pods per plant at 60 and 90 days post-application compared to treatment with 2 water-dispersible sulfur granules 90% according to an embodiment of WO 2008084495. It was noted that plant height in treatment 1 was 11.4% and 14.11% higher at 60 and 90 days after application compared to treatment 2. These are surprisingly good results because treatment 2 composition also contains the same concentration, i.e. 90% sulfur, and has the same particle size distribution as the granular composition processing 1.

Treatment 1 also showed an increase in total plant weight, plant yield, and straw yield compared to Treatment 2. Surprisingly, application of Treatment 1 actually showed an increase in plant weight of 13.46%, plant yield of 11.99%, and an increase in straw yield at harvest by 13.23% compared to treatment 2. It can be said that treatment 2 with a water-dispersible granular sulfur composition according to an embodiment of WO 2008084495 provides an instantaneous absorption of active substances, and this effect is not long-lasting, while the water-degradable granular the composition (treatment 1) of the present invention provides a sustained availability of nutrients throughout the life cycle of the crop, thereby showing surprising results such as higher yields compared to known compositions.

In addition, it was found that the increase in the number of peanut pods per plant and overall yield when using the treatment composition 1 according to an embodiment of the present invention was unexpectedly higher, even when the treatment composition 1 was applied at a dose of only 4 kg per 1 acre, compared with treatment composition 4, containing 90% sulfur bentonite marshmallows, applied at a dose of 8 kg per 1 acre. The selected particle size distribution and the improved suspension and fineness of the water-disintegrating granular composition of Treatment 1 (Table 7 Sample C1) compared to Treatment 3 (Table 7 Sample C3) account for the better performance of Treatment 1 in the field as seen from the above. table, in terms of plant height, number of branches or pods per plant, and yield compared to treatment 3.

It can be seen from the table above that treatment 1 with the 90% water-dispersible sulfur pellets of an embodiment of the present invention exhibits significantly higher sulfur content in peanuts 30, 60 and 90 days after application compared to treatment with 2 water-dispersible 90% sulfur pellets by implementation of WO 2008084495. After treatment 1, the sulfur content increased by 12%, 14% and 10%, respectively, 30, 60 and 90 days after application compared to treatment 2.

In addition, it was found that the increased sulfur uptake when using treatment composition 1 according to an embodiment of the present invention was unexpectedly higher, even when using treatment composition 1 at a dose of only 3 kg per 1 acre, compared with treatment composition 4 containing bentonite sulfur marshmallows. 90% applied at a dose of 8 kg per 1 acre. The improved particle size distribution and increased suspension and fineness of the water-disintegrating granular composition of Treatment 1 (Table 7 Sample C1) compared to Treatment 3 (Table 7 Sample C3) results in better sulfur uptake in Treatment 1 as seen from above. tables.

The higher sulfur content in plant samples 30, 60 and 90 days after treatment 1 confirms the instantaneous and sustained nutrient availability throughout the growing period of the crops according to the embodiments of the pending patent application as opposed to prior art compositions.

Effects of Different Processing Types on Peanut Butter Content

Table 8D

Treatment number Composition Components Dose kg/acre Peanut butter content, % 1 Water-degradable granules zinc oxide 15.5% + boric acid 7.5% + ferrous sulfate 15% according to an embodiment of the present invention 2 52.85 2 Liquid suspension of trace elements zinc oxide 15.5% + boric acid 7.5% + iron sulfate 15% 2 48.89 3 Raw control - 42.2

It can be seen from the above table that treatment of 1 with water-degradable zinc oxide granules 15.5% + boric acid 7.5% + ferrous sulfate 15% according to an embodiment of the present invention showed a significant increase in the content of peanut oil by 12.7% compared with treatment 2 with a liquid suspension of trace elements of zinc oxide 15.5% + boric acid 7.5% + iron sulfate 15%. These results are particularly surprising and can be explained by the form of the composition of the present invention, which instantly and continuously provides nutrients to the crop at the appropriate stages of development in comparison with the treatment composition 2, which reduces the availability of nutrients at later stages of crop development and, in turn, has

- 49 040318 lower efficiency, as can be seen from the table above.

Effects of Different Treatments on Paddy Rice Yields and Yield Parameters

Field trials were carried out to evaluate the effect of different types of processing in the village of Mahij (Barejo) on a type of paddy rice called Bodi (Punjab-S). The area of the land plot was 7.5x3.5=26.25 sq.m. All recommended agricultural practices were observed. Granules of compositions according to embodiments of the invention and the prior art were applied by manual dispersion. Plant height, number of shoots/plant, leaf color, root length, panicle length were measured 30, 60 and 85 days after application. The amount of grain/panicle, biological yield, grain yield and straw yield were also measured. The content of sulfur and zinc in the soil was measured, as well as the absorption of sulfur and zinc by plants. The panicle height was measured in 10 selected plants from each plot for each repetition. Biological yield, yield of grain and straw were recorded from each plot for each repetition and calculated in t/ha.

The observation was documented as shown below.

Table 9

Serial number Processing Dose kg/acre Panicle length (cm) Biological yield (t/ha) Grain yield (t/ha) Straw yield (t/ha) 60 dpo 85 dpp At the time of harvest 1 Water-degradable sulfur granules 70% + zinc oxide 15% (according to an embodiment of the present invention) 4 18.75 20.52 9.50 3.69 6,I 2 In one- dispersible granules of sulfur 70% + zinc oxide 15% prepared as described in WO2012131702 4 17.70 18.10 8.20 3.38 5.52 3 Sulfozinc - sulfur marshmallows 65% + zinc 18% 8 15.45 17.15 7.20 2.66 4.54 4 Sulfur bentonite marshmallows 90% + ZnSO ₄ 33% 10+10 17.70 17.00 7.47 2.84 4.64 5 Water-degradable 85% MAP and 10% sulfur granules according to an embodiment of the present invention 4 17.85 19.72 10.75 3.02 4.87 6 Pellets MAP 85% and sulfur 10% according to embodiment WO2016183685 4 14.48 16.45 7.89 2.65 4.21 7 Raw control - 14.35 14.48 6.30 2.39 4.01

It is clear from the above table that treatment 1 with the water-degradable granular composition of 70% sulfur + 15% zinc oxide according to an embodiment of the present invention showed a significant increase in the amount of rice panicle length 60 and 85 days after application compared to treatment 2 with water- 70% sulfur + 15% zinc oxide dispersible granules prepared as described in WO 2012131702. Treatment 1 also showed a consistent increase in biological yield and straw yield in rice crop compared to treatment 2. Treatment 1 unexpectedly showed an increase in tassel length of 13.37% 85 days after application compared to treatment 2. Treatment 1 also showed an increase in biological yield of 15.85% and approximately 9-10% in grain and straw yield compared to those obtained in treatment 2. It can be said that the composition of this invention provides adequate release of pi 50040318 nutritive substances and makes them available for culture at certain stages of development.

In addition, it was noted that treatment with 3 sulfozinc containing granules of sulfur 65% and zinc

The 18% known in the art showed a slight increase in panicle length and yield compared to Treatment 1, even when Treatment 3 was applied at a rate of 8 kg per acre, twice the rate at which Treatment 1 was used.

The increase in panicle length and yield when using treatment composition 1 containing an agricultural granular composition of sulfur 70% + zinc oxide 15% (according to an embodiment of this invention) was unexpectedly high, even when treatment composition 1 was used at a dose of only 4 kg / acre, compared to treatment composition 4, containing tank mix compositions of bentonite marshmallows 90% sulfur + 33% ZnSO ₄ where bentonite marshmallows 90% sulfur and 33% ZnSO ₄ were used at a dose of 10 kg/acre.

In addition, it was noted that the increase in panicle length and yield observed with treatment composition 5 containing the water-degradable granules of 85% MAP and 10% sulfur according to an embodiment of the present invention was surprisingly high compared to treatment composition 6 containing 85% MAP and 10% sulfur pellets according to WO 2016183685. In fact, treatment 5 showed a 13.96% increase in grain yield and a 15.67% increase in straw yield compared to treatment 6 composition prepared as described in WO 2016183685. Surprising results are observed when treatment composition 5 has the same concentration of active substances as treatment composition 6, except that treatment composition 5 is a water-disintegrating granular form, characterized in that the composition has a lower bulk density and a lower true density compared to treatment composition 6 (prior art). Treatment composition 5 according to an embodiment of the invention is less compacted and is able to release nutrients more gradually due to the lower bulk density and lower true density.

The influence of various types of processing on the yield of corn and other plant parameters

Field trials were carried out to evaluate different types of processing of Kohinoor Delux corn (Bisco bio science) in the village of Laxmanpura (Idar). The area of the land plot was 54 m ² . All recommended agricultural practices were followed. Single spraying of each type of compositions was carried out using a knapsack sprayer. Plant height, leaf color, number of ears/plant, ear length, number of rows of grains/cob, grains/row, ear weight, grain weight, plant weight and yield were monitored before and 30 and 60 days after application. The evaluation results were summarized in a table as shown below.

Table 10

Processing Dose g/ha Cob length (cm) Total plant weight (kg/sq.m) Weight of 100 grains (g) Grain yield (100 kg/ha) Silage yield (100 kg/ha) Water-degradable granules of sulfur 55% + zinc oxide 9.5% + iron oxide 3% obtained according to an embodiment of the present invention 10910 26.13 2.67 28.31 115.47 157.87 Water-degradable sulfur granules 55% + zinc oxide 9.5% + iron oxide 3% + silica 2.5% according to an embodiment of the present invention 10910 27.18 2.78 27.99 111.47 166.53 Water-dispersible granules of sulfur 55% + zinc oxide 9.5% + iron oxide 3% according to WO2012131702 10910 22.56 1.82 24.45 104.22 149.21 Water-dispersible granules of sulfur 55% + zinc oxide 9.5% + iron oxide 3% + silicon dioxide 2.5% according to WO2012131702 10910 24.15 1.92 20.56 101.43 151.24 Control - 1.93 22.01 97.87 94.73

From the above table it can be seen that the treatment of 1 with water-degradable sulfur granules 55% + zinc oxide 9.5% + iron oxide 3% according to an embodiment of this invention at a dose of about

- 51 040318 kg/ha showed a significant increase in total plant weight, grain yield and corn silage compared to treatment 3 with the same composition in the form of water-dispersible granules at the same dosage. Treatment 2 did show a 10.79% increase in grain yield compared to treatment 4. Cob length was also 15.8% longer in treatment 2 compared to treatment 4.

Treatment 2 with water-degradable granules of sulfur 55% + zinc 9.5% + iron 3% + silicon dioxide 2.5% according to an embodiment of the present invention at a dose of about 10 kg/ha of corn compared to treatment 4 with the same composition in the form water-dispersible granules at the same dosage. Treatment 3 showed a 13% increase in cob length and a 9.84% increase in grain yield compared to treatment 6.

Treatments 3 and 4, while providing immediate release and conversion of nutrients for absorption, do not provide nutrients for a longer period of time. The unexpected results of processing 1 and 2 according to the embodiment of the invention are due to the form of the composition, including its hardness, and in particular the fine particle size, which results in an immediate and long-term release of nutrients throughout the entire crop growth cycle.

The observed results were due to the instantaneous and continuous release mechanism of water-disintegrating granular compositions, which first disintegrate and then release the active substances and make the components readily available to plants over a longer period of the crop life cycle. On the other hand, known water-dispersible granular compositions are readily dispersible but release the actives for only a short period of time compared to water-disintegrating granular compositions which provide a sustained release resulting in surprisingly increased yields.

Comparison of the physical properties of water-disintegrating granules of algal active substances.

Table 11

Composition Bulk density (g/ml) Hardness Disintegration time (min) Abrasion resistance Granule size (mm) Average particle size Dispersion (%) Suspension (%) Retention on wet sieve True Density C21 (granules Spirulina 50% according to an embodiment of the invention) 0.46 22.6 N 20 minutes 89% 1.5-4.00 12.5 70 25 1.9 1.41 C22 (granules Chlorella 50% according to option 0.86 30.1 N 85 min 0.72 2.5-5 15.16 30.2 41.5 2.5 1.86 implementation of the invention) C23 Pure Spirulina Powder 0.57 No data No data No data 0.1 mm 50-100 75.1 66.8 5.3 1.34 C24 Pure Chlorella Powder 0.58 No data No data No data 0.1 50 - 120 57.5 33.6 8.5 1.21 C25 pellets coated with algae of the genus Spirulina 50% as described in WO20161136 65 1.6 9H 115 min 0.62 2.5-6 >100 micron not dispersible No data 80 2.7

It can be seen from the above table that sample C21 containing 50% water-degradable algae granules of the genus Spirulina and sample C22 containing 50% water-degradable algae granules of the genus Chlorella obtained in accordance with an embodiment of the present invention , show unexpectedly high abrasion resistance of 89% and 72% and a hardness of 22.6

H and 30.1 N compared to sample C23, which is a powder of algae of the genus

Spirulina (commercial product), and C25, which is a Chlorella algae powder (commercial product), which have no hardness or abrasion resistance at all.

It was also noted that sample C25, which is a 50% Spirulina algae granule, obtained as described in WO 2016113665, where Spirulina is used as the first coating material to form a deformable core together with an aluminosilicate coating over a zeolite granule (substrate), and also as an outer coating (micronized silica), showed a hardness of 9 N, abrasion resistance of only 62%, a wet sieve content of 80% (on a sieve with a pore size of 75 μm) and zero dispersion and suspension, while water-soluble granules algae of the genus Spirulina 50%, obtained according to an embodiment of this invention, have a hardness of 22.6 N, abrasion resistance of 89%, a content on a wet sieve of 1.9% (on a sieve with a pore size of 75 μm) and proper dispersion and suspension. In disintegration tests, prior art granules need to be agitated, which causes them to slowly break down. However, like the bentonite granules (sample A in FIGS. 5 and 6), these prior art granules (sample C25) did not disperse and suspend for several hours, which in turn resulted in poor field performance compared to capable disintegrate in water by the granules of this invention.

Field studies.

Trials were conducted in Chorivad (Idar), Sabarkanta District, India, to evaluate various Hightech corn treatment compositions (Sona). The area of the land plot was 3828 m ² . All recommended agricultural practices were observed. Granules of compositions according to an embodiment of the invention, commercially available algae products and the prior art were applied by hand spreading method. Observations were made on plant height (at 30, 60 and 90 days after application), number of kernels/row, ear weight, grain weight, plant weight, kernel weight and yield. The evaluation was carried out as follows.

Plant height was measured in 10 selected plants from each plot for each replication. Ear counts were recorded at harvest time from 15 selected plants from each plot per replication. Ear weight was measured on 15 selected plants from each plot for each replication. The number of grains was counted in 15 selected plants from each plot for each repetition. The grain weight was determined in 15 selected plants from each plot for each repetition. The total weight of the plant was determined on an area of one square meter from each plot for each repetition. The weight of 100 grains was determined by 100 grains from each plot for each repetition. The yield of grain was determined from an area of one square meter from each plot for each repetition and was calculated at 100 kg/ha and compared with the untreated control.

Husk (%) was calculated by the following formula

Grain weight

Husk % =----------х 100

Cob weight

- 53 040318

Table 12. Influence of different types of processing on the growth and development of corn

Treatment number Composition Components Dose of formulation (g or ml/ha) plant height (cm) Cob weight (g) Number of grains / row Grain weight (g)/cob Husk % thirty Dpp 60 DPP 90 Dpp T1 C21 (granules Spirulina 50% according to an embodiment of the invention) 3000 199.8 0 230.0 3 255.0 7 168.13 34.88 135.60 80.65 T2 C22 (Chlorella granules 50% according to an embodiment of this invention) 3000 198.1 3 229.5 0 254.1 7 167.63 34.07 134.88 80.46 TK C23 (Spirulina algae powder (commercial product)) 1500 195.4 5 227.4 3 252.1 5 164.24 33.27 131.03 79.77 T4 C24 (powder of algae of the genus Chlorella commercial product) 1500 194.3 3 226.7 8 250.9 7 163.75 32.58 130.41 79.63 T5 C25 (pellets coated with algae of the genus Spirulina 50% as described in WO20161136 65) 3000 192.2 1 227.5 6 248.9 8 162.9 32.19 130.11 79.87 Tb WSF (19-1919) 7500 196.5 3 226.8 0 250.6 0 165.86 32.93 131.35 79.19 T7 Control - 190.3 3 219.2 3 246.5 3 159.92 31.87 128.14 80.12

It can be seen from the above table that treatment 1 and 2 with the water-disintegrating granules obtained according to the embodiment of the present invention not only showed an increase in plant height at 30, 60 and 90 days after application, but also showed an increase in cob weight, number of grains, grain weight and percentage of husk compared to treatment 3, 4 and 5 with Spirulina algae powder (commercial product), Chlorella algae powder (commercial product) and Spirulina algae granules 50% prepared as described in WO 2016113665. Poor results observed when using treatment compositions 5 containing the same concentration of algae as treatment 1, may be due to poor dispersion, suspension and high particle size variation of these compositions, as can be seen from table. 11, which ultimately leads to a decrease and short-term availability of these nutrients for crops, resulting in reduced efficiency.

In addition, it was also noted that treatments 1 (at 3000 g/ha) and 2 (at 3000 g/ha) showed an improvement in growth compared to chemical fertilizer WSF (19-19-19) at 7500 g/ha .

- 54 040318

Table 13. Effect of different treatments on corn yield and yield parameters

Treatment number Composition Components Dose of formulation (g or ml/ha) Total plant weight (kg/sq.m) Weight of 100 grains (g) Grain yield (100 kg/ha) T1 C21 (granules Spirulina 50% according to an embodiment of the invention) 2250 2.624 27.80 141.35 T2 C22 (Chlorella granules 50% according to an embodiment of this invention) 3000 2.538 26.59 142.38 TK C23 (Spirulina algae powder (commercial product)) 1500 2.469 25.86 136.60 T4 С24 (powder of algae of the genus Chlorella commercial product) 1500 2.421 23.68 134.52 T5 C25 (pellets coated with algae of the genus Spirulina 50% as described in WO2016113665) 3000 2.402 24.93 133.9 Tb WSF (19-19-19) 7500 2.417 25.87 136.45 T7 Control - 2.242 23.02 128.95

From the table above, it can be seen that treatment 1 and 2 with water-disintegrating granules obtained according to an embodiment of this invention showed a percentage increase in yield of 3.4% and 5.8% compared with treatment 3 and 4 with powder of algae of the genus Spirulina ( commercial product), Chlorella algae powder (commercial product), respectively. Treatment 1 also unexpectedly provided a yield increase of 5.5% over treatment 5.

Comparison of the physical properties of pesticidal active substances.

- 55 040318

Table 14

Sample Composition Components Bulk density (g/ml) Hardness (newton) Disintegration time (min) Abrasion resistance Granule size (mm) Average particle size (µm) (D50) Dieps (%) Suspension Retention on a wet sieve with a pore size of 75 µm (%) True charge (g/cm3) C26 Water-disintegrating granules of chlorantraniliprole 0.4% according to an embodiment of the present invention 1.2 32.4 12 95 2.54.00 45 42.2 36.1 19 2.2 C27 Chloranthraniliprol granules GR0.4% (prior art sand granules) 1.04 Data not available, too fine Do not disintegrate 99 2.0-3.0 250- 840 µm 1.38% 0.8% 35 2.57 C28 Water-degradable granules of carboxin 37.5% + thiram 37.5% according to an embodiment of this invention 0.90 30.3 9 88 2.54.5 eleven 48.2 39.8 5.1 1.92 C29 Carboxin 1.4 Dan- Data 5.5 Data 7 41.5 31.6 1.9 1.85 37.5% + thiram 37.5% WP(Vitavax) None missing missing

Bioefficiency of water-disintegrating granular compositions containing pesticidal active substances.

Tests were conducted in the Karnal region of Haryana, India, on paddy rice crops to evaluate the effectiveness of water-disintegrating 0.4% chloranthraniprole granules according to an embodiment of the present invention at various dosages. Experiments were also performed using chloranthraniprol GR 0.4% (prior art sand grains) for comparison as well as an untreated control. Treatments were carried out in accordance with the scheme of randomized blocks and subject to the same agricultural practices for all types of treatments.

The treatments were carried out by spreading the compositions on the 30th day after paddy rice transplantation. Both the types of treatments themselves and their effectiveness were evaluated. Temporary mounds 20 to 30 cm thick were erected around areas treated with granular insecticides to avoid mixing of treatments.

The processing methods used are shown in the table below.

-56040318

Table 15

Serial number Processing Dose (l or kg/ha) 15 DPP 30 dpo 45 DPP 60 dpp Average 1 Granules of chlorantraniliprole 0.4% according to the embodiment of the present invention 10 0 4.13 5.9 13.64 7.59 2 Granules of chlorantraniliprol 0.4% of the prior art 10 0 5.09 7.53 17.86 10.16 3 Raw control - 0 7.08 9.8 48.38 21.75

*DAP - days after application *Average - average calculated from the average of the % of plants infested with stem borers at 15 DAP, 30 DAP, 45 DAP and 60 DAP

It was noted that the use of water-degradable granules of chlorantraniliprole 0.4% according to an embodiment of this invention at a dose of 10 kg/ha (treatment 1) was highly effective (% of plants affected by stem borer after treatment 1 had an average value of 7.59% ) in stem borer control compared to the known composition of 0.4% chlorantraniliprole GR (treatment 2) (% of plants affected by stem borer after treatment 2 had an average value of 10.16%) at the same dosages after 30, 45 and 60 days after application.

The inventors have determined for the first time that the combination of precisely matched properties of low bulk density, high mechanical strength or hardness, fine particle size distribution within the granule size results in compositions that not only provide immediate, but also continuous and sustained release and effect on crops. when applied to soil. This composition can be adapted to specific crops, so it is effective for immediate and sustained release of agrochemical actives. The composition not only provides a slow release of a water-insoluble nutrient or algae or pesticide, but can also ensure that the active substance is completely converted into an uptake form, thereby preventing leaching and pollution of groundwater or rivers. The composition provides uniform application by spreading or mechanical applicators, and also allows the simultaneous application of various types of fertilizers with the composition of this invention, thereby providing extremely high efficiency in field application compared to traditional compositions. Because of its ease of use, this composition is extremely economical for the end user.

From the foregoing, it will be understood that numerous modifications and variations may be realized within and within the scope of the novel concepts of the present invention. It is to be understood that no limitation is intended or intended to be given to the specific embodiments illustrated.

Claims (24)

1. Disintegrating in water granular composition containing at least one agrochemical active substance, which contains either a water-insoluble nutrient, or algae, or pesticidal active substance, in the concentration range from 0.1 to 95% by weight; and at least one agrochemically acceptable excipient; wherein the granule size of the water-disintegrating granular composition is from 0.1 to 6 mm, with a particle size of 0.1 to 50 μm; at the same time, the granular composition disintegrating in water has a bulk density of less than 1.5 g/ml and a hardness of at least 1 N. 2. The water disintegrating granular composition according to claim 1, which has an abrasion resistance of at least 50%. 3. The water disintegrating granular composition according to claim 1, which has a retention value on a wet sieve with a pore size of 75 µm of less than 30%. 4. The water disintegrating granular composition according to claim 1, which has a wet sieve analysis value on a sieve with a pore size of 75 µm of less than 10%. 5. The water disintegrating granular composition according to claim 1, which has a true density of less than 2.5 g/ml. 6. The water disintegrating granular composition according to claim 1, which has an abrasion resistance of at least 70%. - 57 040318 7. Water-disintegrating granular composition according to claim 1, the disintegration time of which is less than 200 minutes. 8. Water disintegrating granular composition according to claim 1, the disintegration time of which is less than 100 minutes. 9. Water-disintegrating granular composition according to claim 1, which has a dispersion of at least 10%. 10. The water disintegrating granular composition according to claim 1, which has a suspension capacity of at least 10%. 11. The water disintegrating granular composition according to claim 1, which contains granules ranging in size from 1 to 6 mm. 12. The water disintegrating granular composition according to claim 1, which contains granules of predominantly spherical shape. 13. The water-disintegrating granular composition of claim 1, wherein the water-insoluble nutrient contains the elemental boron, calcium, chlorine, chromium, cobalt, copper, fluorine, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium , silicon, sodium, zinc or their salts or derivatives. 14. The water-disintegrating granular composition of claim 1, wherein the water-insoluble nutrients comprise at least one of the following compounds: elemental sulfur, elemental boron, boron carbide, boron nitride, aluminum oxide, aluminum dodecaboride, aluminum hydroxide, bauxite, calcite limestone, calcium oxalate, chromium oxide, cobalt oxide, cobalt sulfide, cobalt molybdate, cobalt carbonate, copper oxalate, copper oxide, copper sulfide, copper hydroxide, copper sulfide, copper phosphate, copper molybdate, fluorine oxide, fluorine molybdate, iron oxide , iron sulfide, magnesium oxide, magnesium hydroxide, tribasic magnesium phosphate, magnesium molybdate, magnesium carbonate, manganese oxide, manganese molybdate, molybdenum acetate, molybdenum disulfide, selenium sulfide, silicon nitride, zinc sulfide, zinc oxide, zinc carbonate, zinc phosphate, zinc molybdate, basic slag, elemental chromium, chromium phosphate, iron sucrates, cobalt phosphide, cobalt cyanide, elemental nickel, nickel oxide, nickel oxyhydroxide, ka Nickel Carbonate, Nickel Chromate, Nickel Hydroxide, Millerite, Nickel Selenide, Nickel Phosphide, Elemental Copper, Insoluble Copper Cyanide, Chalcocite, Copper Selenide, Copper Phosphide, Covellite, Copper Arsenate, Elemental Silver, Elemental Zinc, Zinc Chromate, Zinc Pyrophosphate, Hydroxide tin, tin oxide and tin sulfide, their salts, derivatives and combinations thereof. 15. The water-disintegrating granular composition of claim 1, wherein the agrochemically acceptable excipients comprise one or more surfactants, binders, diluents, disintegrants, fillers, adhesives, and pH stabilizers. 16. The water-disintegrating granular composition of claim 1, wherein the composition further comprises one or more water-insoluble nutrients, algae, microbes, biostimulants, biofertilizers, pesticide actives, water-soluble fertilizers, macronutrients and micronutrients. 17. The water-disintegrating granular composition of claim 1, wherein the agrochemically acceptable excipients are selected from either surfactants or dispersants or binders. 18. The water-disintegrating granular composition according to claim 1, wherein the ratio of algae to agrochemically acceptable excipients is between 99:1 and 1:99. 19. The water-disintegrating granular composition of claim 1, wherein the algae comprises one or more green algae, red algae, golden algae, brown algae, golden brown algae, blue algae or blue-green algae, Asian flat algae, or marine algae, or their derivatives, species and combinations. 20. Water-disintegrating granular composition according to claim 19, wherein the algae contain one or more of the group of bacteria: Cyanobacteria, Phaeophyceae, Ochrophytes, Glaucophytes, Rhodoplasts, Rhodophytes, Chloroplasts, Ochrophytes, Chrysophyta, Raphidiophyceae, Eumastigophyceae, Xanthophyceae, Synurophytes, Silicoflagellata , Sarcinochrysophyceae, Heterokonts, Crytophytes, Haptophytes, Euglenophytes, Chlorophytes, Charophytes, Land Plants, Embrophyta, or Chlorarachniophytes, or derivatives, species, and combinations thereof. 21. The water-disintegrating granular composition of claim 1, wherein the algal component comprises Chlorella Sp. 22. The water-disintegrating granular composition of claim 1, wherein the algal component comprises Spirulina Sp. 23. Water disintegrating granular composition according to claim 1, in which the pesticidal active substance contains at least one of the group of compounds: antifoulants, attractants, insecticides, fungicides, herbicides, nematicides, pheromones, defoliants, acaricides, plant growth regulators, algicides, antifeedants , avicides, bactericides, bird repellents, biopesticides, biocides, chemosterilants, protectants, insect attractants, insect repellents, insect growth regulators, mammal repellents, male decoys, disinfectants, molluscicides, antimicrobial agents, miticides, - 58 040318 ovicides, fumigants, plant activators, rodenticides, synergists, virucides, repellents, microbial pesticides, incorporated plant protectants or their salts, derivatives and combinations. 24. Method for obtaining a water-disintegrating granular composition according to π. 1, which includes grinding a mixture of at least one agrochemical active substance, which contains either a water-insoluble nutrient, or an algae, or a pesticidal active substance; at least one agrochemically acceptable excipient and water to obtain a wet mix; drying the wet mixture to obtain microgranules; agglomerating the microgranules in a granulator to obtain a water disintegrating granular composition with a granule size of 0.1 to 6 mm and a particle size of 0.1 to 50 µm; at the same time, the granular composition disintegrating in water has a bulk density of less than 1.5 g/ml and a hardness of at least 1 N.