EA037509B1 - Method for improving electrical conductivity and increasing efficiency of a dimexide solution during iontophoresis - Google Patents

Abstract

The invention relates to medicine, in particular to physiotherapy and is proposed as a method of treatment in general medical practice using a dimexide solution during iontophoresis. The object of the invention is to improve the electrical conductivity and to increase the efficiency of the dimexide solution during iontophoresis. The object is achieved by diluting the dimexide solution with distilled water and preparing a solution with concentration of 5-10%, to which a 0.2% potassium chloride solution is added.

Description

The invention relates to medicine, in particular to physiotherapy, and is proposed as a method of treatment in general medical practice using a solution of Dimexide in the process of drug electrophoresis.

Medicinal solutions used for electrophoresis are prepared with distilled water. It should be noted that distilled water is used as a solvent for the preparation of all types and concentrations of aqueous solutions used in electrophoresis.

To date, science has proven that a solution of Dimexide can be used as a remedy for drug electrophoresis.

As a prototype, the method of using a standard 99% solution of Dimexide with different concentrations, diluted with distilled water, is chosen, but most often weak concentrations (5-10%) of a solution of Dimexide are used to perform this procedure. It is the Dimexide solution of this concentration that has found the most widespread use in medical practice [1].

The disadvantage of the existing method of using a solution of Dimexide when using it as an agent in the process of drug electrophoresis is as follows: the use of this agent in medical practice remains not fully scientifically substantiated, since this does not form active bipolar ions of Dimexide in this solution and Dimexide remains electrically neutral , where in an electric field it behaves like a zwitter-solvated and inactive ion, which is not able to move to any electric pole during drug electrophoresis.

The purpose of the proposed invention is aimed at solving the problems of ensuring electrical conductivity and increasing the efficiency of the Dimexide solution and enhancing its therapeutic effect in the process of drug electrophoresis.

This goal is achieved by adding a solution of potassium chloride to improve the electrical conductivity and increase the efficiency of the dimexide solution.

The essence of the invention lies in the fact that to obtain a solution of Dimexide with a concentration (5-10%), a 0.2% solution of potassium chloride is added to a standard 99% solution of Dimexide to obtain the resulting solution in different volumes. In the resulting solution, the appearance of the electrical conductivity of the dimexide solution occurs due to the formation of solvate ions with the superiority of positive ions in this agent. This electrophoretic phenomenon contributes to the fact that the electrical conductivity of the dimexide solution and its effectiveness in the process of drug electrophoresis increase. In the process of formation of solvated ions (positive and negative) surrounding the bipolar molecule of dimexide, a system is formed consisting of uneven amounts of positive and negative charged conglomeres with the advantage of a positive charge related to one end (potassium element).

This method provides an improvement in electrical conductivity and an increase in the efficiency of the Dimexide solution and enhancement of its therapeutic effect in the process of drug electrophoresis.

Method of preparation of the applied solution

To use a solution of Dimexide in drug electrophoresis and to obtain a solution of Dimexide with the desired concentration of 5-10%, 0.2% potassium chloride solution is added to a standard 99% solution of Dimexide to obtain the resulting solution in different volumes. To obtain the required volume and concentration of a solution of dimexide with potassium chloride, proceed as follows: medicinal solutions used for electrophoresis are prepared in distilled water. To obtain a composition consisting of a 10% solution of dimexide and a 0.2% solution of potassium chloride used for electrophoresis, the following procedure is performed: for the manufacture of 200.0 ml of the above composition, 171.0 ml of dis.water, 18.5 ml of 99% an aqueous solution of Dimexide and 10.0 ml of a 4% solution of potassium chloride.

Example 1. Patient K., born in 1963, diagnosed with osteochondrosis of the lumbosacral spine with radicular syndrome. Complaints of the patient of burning pain in the lumbosacral region with irradiation in the lower extremities, with limited mobility in the lumbosacral region, difficulty walking. After the conventional drug therapy and the unsatisfactory effect of it, the patient was prescribed a course of 10 electrophoresis procedures with 10% Dimexide solution (+) on the lumbosacral spine and 2.4% aminophylline solution (-) on the area of both calf muscles. The exposure time was 15 to 20 minutes daily, the course of treatment was 10 procedures. After taking the procedures, the patient got rid of pain and stiffness in the lower back, the pain of a radiating nature in the lower extremities disappeared.

Example 2. Patient S., born in 1967, diagnosed with lumbosacral radiculitis with radicular syndrome. Complaints of radiating pain in the lower extremities, in particular in the right leg. After the conventional drug therapy and the persistence of complaints, the patient was prescribed a course of 10 electrophoresis procedures with 10% Dimexide solution (+) on the lumbosacral spine and 2.4% aminophylline solution (-) on the right gastrocnemius muscle. The exposure time was 15 to 20 minutes daily, the course of treatment was 10 procedures. After taking the procedures, the patient

- 1 037509 completely got rid of the existing complaints, the radiating pains disappeared, the previous rhythm of walking was restored.

Based on this, it can be stated that this method of using a solution of Dimexidum is proposed as a method of physiotherapeutic treatment when carrying out medicinal electrophoresis and its application will be based on scientific facts of the correctness and feasibility of this method.

Literature

1. Guidelines for the treatment of internal diseases under. ed. prof. Okorokova A.N.

Claims (1)

CLAIM A method for improving electrical conductivity and increasing the efficiency of a dimexide solution in the process of drug electrophoresis, comprising diluting a solution of dimexide with distilled water and obtaining a solution with a concentration of 5-10%, characterized in that a 0.2% solution of potassium chloride is added to it.