DZ2786A1 - Préparation pharmaceutique de sildénafil à délitement oral et procédé por sa production. - Google Patents

Préparation pharmaceutique de sildénafil à délitement oral et procédé por sa production.

Info

Publication number
DZ2786A1
DZ2786A1 DZ990086A DZ990086A DZ2786A1 DZ 2786 A1 DZ2786 A1 DZ 2786A1 DZ 990086 A DZ990086 A DZ 990086A DZ 990086 A DZ990086 A DZ 990086A DZ 2786 A1 DZ2786 A1 DZ 2786A1
Authority
DZ
Algeria
Prior art keywords
sildenafil
production
pharmaceutical preparation
oral disintegration
disintegration
Prior art date
Application number
DZ990086A
Other languages
English (en)
Inventor
Cristi Bell-Huff
Thomas Francis Dolan
Angea Carol Gatlin Hausberger
Original Assignee
Pfoer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfoer Inc filed Critical Pfoer Inc
Application granted granted Critical
Publication of DZ2786A1 publication Critical patent/DZ2786A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Silicon Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DZ990086A 1998-05-15 1999-05-12 Préparation pharmaceutique de sildénafil à délitement oral et procédé por sa production. DZ2786A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8564698P 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
DZ2786A1 true DZ2786A1 (fr) 2003-12-01

Family

ID=22193027

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ990086A DZ2786A1 (fr) 1998-05-15 1999-05-12 Préparation pharmaceutique de sildénafil à délitement oral et procédé por sa production.

Country Status (32)

Country Link
US (1) US20020002172A1 (fr)
EP (1) EP0960621A3 (fr)
JP (1) JPH11349483A (fr)
KR (1) KR19990088249A (fr)
CN (1) CN1251758A (fr)
AP (1) AP9901534A0 (fr)
AR (1) AR016481A1 (fr)
AU (1) AU753478B2 (fr)
BG (1) BG103396A (fr)
BR (1) BR9902086A (fr)
CA (1) CA2272042A1 (fr)
CO (1) CO5060503A1 (fr)
DZ (1) DZ2786A1 (fr)
EA (1) EA002830B1 (fr)
GT (1) GT199900061A (fr)
HN (1) HN1999000066A (fr)
HR (1) HRP990144A2 (fr)
HU (1) HUP9901606A2 (fr)
ID (1) ID23299A (fr)
IS (1) IS5046A (fr)
MA (1) MA26629A1 (fr)
NO (1) NO992339L (fr)
NZ (1) NZ335772A (fr)
OA (1) OA11040A (fr)
PA (1) PA8472901A1 (fr)
PE (1) PE20000546A1 (fr)
PL (1) PL333118A1 (fr)
SG (1) SG79255A1 (fr)
SK (1) SK61599A3 (fr)
TR (1) TR199901077A3 (fr)
YU (1) YU21999A (fr)
ZA (1) ZA993338B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1120120A4 (fr) * 1998-10-05 2009-04-29 Eisai R&D Man Co Ltd Comprimes se delitant immediatement dans la cavite buccale
WO2000053148A2 (fr) * 1999-03-08 2000-09-14 Merck & Co., Inc. Procedes et compositions pour le traitement de la dyserection
AU3744800A (en) * 1999-03-16 2000-10-04 Pentech Pharmaceuticals, Inc. Controlled release of sildenafil delivered by sublingual or buccal administration
AU3574500A (en) * 1999-03-25 2000-10-16 Yuhan Corporation Rapidly disintegrable tablet for oral administration
KR100344198B1 (ko) * 1999-10-08 2002-07-19 일양약품주식회사 실데나필 시트레이트의 속효제형
ES2381862T3 (es) 2000-09-06 2012-06-01 Mitsubishi Tanabe Pharma Corporation Preparaciones para administración por vía oral
US6733781B2 (en) 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
IN192750B (fr) * 2000-12-15 2004-05-15 Ranbaxy Lab Ltd
US6544552B2 (en) * 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
EP1226818A1 (fr) * 2001-01-26 2002-07-31 Pfizer Products Inc. Formulation pharmaceutique présentant des propriétés de cohesion et de compressibilité améliorées
BR0209541A (pt) * 2001-05-09 2004-04-20 Bayer Healthcare Ag Uso das imidazotriazinonas 2-fenil-substituìdas
LV12978B (en) * 2001-09-07 2003-05-20 Ivars Kalvins Pharmaceutical composition
CN1284532C (zh) * 2001-09-28 2006-11-15 株式会社三和化学研究所 有核型速溶崩解性成型品
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
SE0202365D0 (sv) * 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
US7638138B2 (en) 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
USRE45404E1 (en) 2003-03-27 2015-03-03 Shin Nippon Biomedical Laboratories, Ltd. Powder medicine applicator for nasal cavity
US20050042177A1 (en) * 2003-07-23 2005-02-24 Elan Pharma International Ltd. Novel compositions of sildenafil free base
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
DE102004023069A1 (de) * 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
EP1785145A4 (fr) * 2004-08-10 2008-08-13 Translational Res Ltd Composition transnasale dont l'action est immediate et l'absorbabilite est elevee
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
CA2612917A1 (fr) * 2005-06-23 2007-01-04 Schering Corporation Formulations orales a absorption rapide d'inhibiteurs de la pde5
KR20080056250A (ko) * 2005-09-29 2008-06-20 바이엘 헬스케어 아게 비뇨기 장애의 치료를 위한 ｐｄｅ 억제제 및 이들의 조합
EP2116264B1 (fr) * 2006-12-26 2017-09-27 Shin Nippon Biomedical Laboratories, Ltd. Préparation pour administration transnasale
CA2677691C (fr) * 2007-02-12 2012-07-31 David Bar-Or Reduction des effets secondaires du tramadol
US20100184769A1 (en) * 2007-06-13 2010-07-22 Bayer Schering Pharma Aktiengesellschaft Pde inhibitors for the treatment of hearing impairment
FR2932682B1 (fr) * 2008-06-23 2013-07-12 Bionetwork Nouvelles formes pharmaceutiques a effet rapide et les utilisations des compositions pharmaceutiques ainsi obtenus.
MX2011009053A (es) 2009-03-09 2012-04-02 Spi Pharma Inc Excipientes de compresion directa con alta capacidad de compactacion y durables y sistemas de excipiente.
DE102009016584A1 (de) 2009-04-06 2010-10-07 Ratiopharm Gmbh Schmelztablette, enthaltend ein Sildenafil-Salz
WO2010131486A1 (fr) * 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Compositions pharmaceutiques intranasales avec pharmacocinétique améliorée
US8827946B2 (en) * 2009-07-31 2014-09-09 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
WO2011030351A2 (fr) 2009-09-03 2011-03-17 Rubicon Research Private Limited Compositions pharmaceutiques au goût masqué
EP2338474A1 (fr) * 2009-12-23 2011-06-29 Ratiopharm GmbH Comprimé orodispersible contenant une base de sidénafil compactée
DE102010024866A1 (de) * 2010-06-24 2011-12-29 Pharmatech Gmbh Formulierung zur Geschmacksmaskierung
SG192284A1 (en) * 2011-02-11 2013-09-30 Ctc Bio Inc Sildenafil-free base-containing film preparation and method for producing same
KR101418406B1 (ko) * 2011-08-24 2014-07-10 한미약품 주식회사 실데나필 유리 염기를 포함하는 구강 붕해정
MX366768B (es) * 2011-12-08 2019-07-17 Laboratorios Liomont S A De C V Tableta orodispersable de sildenafil y metodo para preparar la misma.
KR102239291B1 (ko) 2013-06-28 2021-04-14 한미약품 주식회사 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 저작정 제제
CN105769887B (zh) * 2014-12-23 2019-04-30 上海复星星泰医药科技有限公司 一种复方果糖二磷酸钠果糖口崩片及其制备方法
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN114246835A (zh) * 2022-01-05 2022-03-29 河北龙海药业有限公司 一种枸橼酸西地那非口腔崩解片的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2246013A1 (de) * 1972-09-20 1974-03-28 Boehringer Mannheim Gmbh Verfahren zur herstellung von poroesen tabletten
US5624677A (en) * 1995-06-13 1997-04-29 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
DE19532142A1 (de) * 1995-08-31 1997-03-06 Siemens Ag Verfahren und Vorrichtung zur Regelung eines vierdimensionalen Vektors einer Strecke mittels eines wertediskreten Stellgliedes mit begrenzter Schaltfrequenz
GB9523752D0 (en) * 1995-11-21 1996-01-24 Pfizer Ltd Pharmaceutical formulations
BR9809508A (pt) * 1997-05-29 2000-06-20 Mochida Pharm Co Ltd Agente terapêutico para disfunção de ereção
TW542719B (en) * 1998-02-23 2003-07-21 Pfizer Res & Dev Method of treating impotence due to spinal cord injury
US6124461A (en) * 1998-05-26 2000-09-26 Saint Louis University, Health Services Center, Research Administration Compounds, compositions, and methods for treating erectile dysfunction
AU3744800A (en) * 1999-03-16 2000-10-04 Pentech Pharmaceuticals, Inc. Controlled release of sildenafil delivered by sublingual or buccal administration

Also Published As

Publication number Publication date
HUP9901606A2 (en) 2002-09-28
SG79255A1 (en) 2001-03-20
TR199901077A2 (en) 1999-12-21
EA002830B1 (ru) 2002-10-31
AU2812699A (en) 1999-11-25
ZA993338B (en) 2000-11-14
AP9901534A0 (en) 1999-06-30
ID23299A (id) 2000-04-05
CN1251758A (zh) 2000-05-03
PL333118A1 (en) 1999-11-22
HRP990144A2 (en) 2000-02-29
CA2272042A1 (fr) 1999-11-15
EA199900373A3 (ru) 2000-08-28
US20020002172A1 (en) 2002-01-03
TR199901077A3 (tr) 1999-12-21
EP0960621A3 (fr) 2000-01-05
EP0960621A2 (fr) 1999-12-01
NZ335772A (en) 2000-12-22
NO992339L (no) 1999-11-16
BR9902086A (pt) 2000-05-02
MA26629A1 (fr) 2004-12-20
NO992339D0 (no) 1999-05-14
OA11040A (en) 2003-01-01
PE20000546A1 (es) 2000-07-07
CO5060503A1 (es) 2001-07-30
JPH11349483A (ja) 1999-12-21
BG103396A (bg) 2000-01-31
PA8472901A1 (es) 2000-09-29
AR016481A1 (es) 2001-07-04
YU21999A (sh) 2002-03-18
EA199900373A2 (ru) 1999-12-29
HU9901606D0 (en) 1999-07-28
SK61599A3 (en) 2000-12-11
HN1999000066A (es) 1999-09-29
GT199900061A (es) 2000-10-14
IS5046A (is) 1999-11-16
KR19990088249A (ko) 1999-12-27
AU753478B2 (en) 2002-10-17

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