DOP2015000068A - SYNERGIC COMPOSITION OF NITAZOXANIDA AND MEBENDAZOL, PROCESSES TO PREPARE IT AND THE USE OF SUCH COMPOSITION FOR THE TREATMENT OF HUMAN PARASITOSIS - Google Patents
SYNERGIC COMPOSITION OF NITAZOXANIDA AND MEBENDAZOL, PROCESSES TO PREPARE IT AND THE USE OF SUCH COMPOSITION FOR THE TREATMENT OF HUMAN PARASITOSISInfo
- Publication number
- DOP2015000068A DOP2015000068A DO2015000068A DO2015000068A DOP2015000068A DO P2015000068 A DOP2015000068 A DO P2015000068A DO 2015000068 A DO2015000068 A DO 2015000068A DO 2015000068 A DO2015000068 A DO 2015000068A DO P2015000068 A DOP2015000068 A DO P2015000068A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- ntzx
- mbdz
- composition
- treatment
- pharmaceutical combination
- Prior art date
Links
Abstract
La presente invención se refiere a una composición farmacéutica sinérgica para el tratamiento de parasitosis humana de Mebendazol (MBDZ) con Nitazoxanida (NTZX), que amplía significativamente el espectro del MBDZ contra protozoos y refuerza la acción antihelmíntica de la NTZX. Además, al usar dicha combinación farmacéutica de MBDZ y NTZX, la acción sistémica del metabolito activo de la NTZX, la Tizoxanida, y el tratamiento de algunas formas sistémicas de parasitosis, mantienen los mismos efectos de los principios activos individuales. También, la combinación farmacéutica sinérgica de MBDZ con NTZX logra un mayor espectro antiparasitario, mientras mantienen la eficacia y los perfiles de seguridad de ambos principios activos por separado. Todos estos efectos permiten que la combinación farmacéutica de la presente invención se diferencie del resto de los tratamientos antiparasitarios clásicos que tienen espectros más acotados. Los efectos sinérgicos de la combinación farmacéutica MBDZ y NTZX son, por consiguiente, el objeto principal de la presente invención.The present invention relates to a synergistic pharmaceutical composition for the treatment of human parasitosis of Mebendazole (MBDZ) with Nitazoxanide (NTZX), which significantly broadens the spectrum of the MBDZ against protozoa and reinforces the anthelmintic action of NTZX. Furthermore, by using said pharmaceutical combination of MBDZ and NTZX, the systemic action of the active metabolite of NTZX, Tizoxanide, and the treatment of some systemic forms of parasitosis, maintain the same effects of individual active ingredients. Also, the synergistic pharmaceutical combination of MBDZ with NTZX achieves a greater antiparasitic spectrum, while maintaining the efficacy and safety profiles of both active ingredients separately. All these effects allow the pharmaceutical combination of the present invention to be distinguished from the rest of the classic antiparasitic treatments that have more narrow spectra. The synergistic effects of the pharmaceutical combination MBDZ and NTZX are, therefore, the main object of the present invention.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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DO2015000068A DOP2015000068A (en) | 2015-03-20 | 2015-03-20 | SYNERGIC COMPOSITION OF NITAZOXANIDA AND MEBENDAZOL, PROCESSES TO PREPARE IT AND THE USE OF SUCH COMPOSITION FOR THE TREATMENT OF HUMAN PARASITOSIS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DO2015000068A DOP2015000068A (en) | 2015-03-20 | 2015-03-20 | SYNERGIC COMPOSITION OF NITAZOXANIDA AND MEBENDAZOL, PROCESSES TO PREPARE IT AND THE USE OF SUCH COMPOSITION FOR THE TREATMENT OF HUMAN PARASITOSIS |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2015000068A true DOP2015000068A (en) | 2015-05-31 |
Family
ID=53274302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2015000068A DOP2015000068A (en) | 2015-03-20 | 2015-03-20 | SYNERGIC COMPOSITION OF NITAZOXANIDA AND MEBENDAZOL, PROCESSES TO PREPARE IT AND THE USE OF SUCH COMPOSITION FOR THE TREATMENT OF HUMAN PARASITOSIS |
Country Status (1)
Country | Link |
---|---|
DO (1) | DOP2015000068A (en) |
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2015
- 2015-03-20 DO DO2015000068A patent/DOP2015000068A/en unknown
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