DOP2009000132A - AKT ACTIVITY INHIBITORS - Google Patents

AKT ACTIVITY INHIBITORS

Info

Publication number
DOP2009000132A
DOP2009000132A DO2009000132A DO2009000132A DOP2009000132A DO P2009000132 A DOP2009000132 A DO P2009000132A DO 2009000132 A DO2009000132 A DO 2009000132A DO 2009000132 A DO2009000132 A DO 2009000132A DO P2009000132 A DOP2009000132 A DO P2009000132A
Authority
DO
Dominican Republic
Prior art keywords
akt
akt activity
activity inhibitors
compounds
activity
Prior art date
Application number
DO2009000132A
Other languages
Spanish (es)
Inventor
Michael J Kelly Iii
Mark E Layton
Philip E Sanderson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to DO2009000132A priority Critical patent/DOP2009000132A/en
Publication of DOP2009000132A publication Critical patent/DOP2009000132A/en

Links

Abstract

La presente invención proporciona compuestos de naftiridina sustituidos que inhiben la actividad de la Akt. En particular, los compuestos descritos inhiben de manera selectiva una o dos de las isoformas de la Akt. La invención tambien proporciona composiciones que comprenden tales compuestos inhibidores y procedimientos de inhibición de la actividad de la Akt mediante la administración del compuesto a un paciente en necesidad de tratamiento de cáncer.The present invention provides substituted naphthyridine compounds that inhibit the activity of Akt. In particular, the compounds described selectively inhibit one or two of the isoforms of Akt. The invention also provides compositions comprising such inhibitor compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of cancer treatment.

DO2009000132A 2009-06-05 2009-06-05 AKT ACTIVITY INHIBITORS DOP2009000132A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2009000132A DOP2009000132A (en) 2009-06-05 2009-06-05 AKT ACTIVITY INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2009000132A DOP2009000132A (en) 2009-06-05 2009-06-05 AKT ACTIVITY INHIBITORS

Publications (1)

Publication Number Publication Date
DOP2009000132A true DOP2009000132A (en) 2009-08-15

Family

ID=44680891

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2009000132A DOP2009000132A (en) 2009-06-05 2009-06-05 AKT ACTIVITY INHIBITORS

Country Status (1)

Country Link
DO (1) DOP2009000132A (en)

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