DOP2006000167A - METAL COMPLEXES WITH CONTENT OF PERFLUOROQUILO, PROCEDURES FOR THEIR PREPARATION, AS WELL AS ITS USE - Google Patents

METAL COMPLEXES WITH CONTENT OF PERFLUOROQUILO, PROCEDURES FOR THEIR PREPARATION, AS WELL AS ITS USE

Info

Publication number
DOP2006000167A
DOP2006000167A DO2006000167A DO2006000167A DOP2006000167A DO P2006000167 A DOP2006000167 A DO P2006000167A DO 2006000167 A DO2006000167 A DO 2006000167A DO 2006000167 A DO2006000167 A DO 2006000167A DO P2006000167 A DOP2006000167 A DO P2006000167A
Authority
DO
Dominican Republic
Prior art keywords
procedures
preparation
content
well
metal complexes
Prior art date
Application number
DO2006000167A
Other languages
Spanish (es)
Inventor
Bernd Misselwitz
Hanns-Joachim Weinmann
Heiko Schirmer
Johannes Platzek
Lubwig Zorn
Heribert Schmitt-Willich
Thomas Brumby
Joerg Meding
Original Assignee
Schering Ag
Epix Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Epix Pharm Inc filed Critical Schering Ag
Publication of DOP2006000167A publication Critical patent/DOP2006000167A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invencion se refiere a los objetos caracterizados en las reivindicaciones, a saber, complejos metalicos con contenido de perfluoroalquilo con radicales con nitrogeno de la formula general I, a procedimientos para su preparacion y a su use en el diagnostico por RMN y rayos X, en el radiodiagnostico y la radioterapia, asi como en la linfografia MRT y para la representacion de la acumulacion de sangre por imagenes.The invention relates to the objects characterized in the claims, namely, metal complexes containing perfluoroalkyl content with nitrogen radicals of the general formula I, procedures for their preparation and their use in the diagnosis of NMR and X-rays, in the radiodiagnosis and radiotherapy, as well as in MRT lymphography and for the representation of blood accumulation by images.

DO2006000167A 2005-07-15 2006-07-13 METAL COMPLEXES WITH CONTENT OF PERFLUOROQUILO, PROCEDURES FOR THEIR PREPARATION, AS WELL AS ITS USE DOP2006000167A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005033902A DE102005033902B3 (en) 2005-07-15 2005-07-15 Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DOP2006000167A true DOP2006000167A (en) 2007-02-28

Family

ID=37057146

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2006000167A DOP2006000167A (en) 2005-07-15 2006-07-13 METAL COMPLEXES WITH CONTENT OF PERFLUOROQUILO, PROCEDURES FOR THEIR PREPARATION, AS WELL AS ITS USE

Country Status (22)

Country Link
EP (1) EP1904463A2 (en)
JP (1) JP2009501174A (en)
KR (1) KR20080043762A (en)
CN (1) CN101223148A (en)
AR (1) AR054865A1 (en)
AU (1) AU2006272025A1 (en)
BR (1) BRPI0613407A2 (en)
CA (1) CA2615443A1 (en)
CR (1) CR9645A (en)
DE (1) DE102005033902B3 (en)
DO (1) DOP2006000167A (en)
EC (1) ECSP088100A (en)
GT (1) GT200600313A (en)
IL (1) IL187926A0 (en)
NO (1) NO20080813L (en)
PE (1) PE20070376A1 (en)
RU (1) RU2008105356A (en)
TN (1) TNSN08016A1 (en)
TW (1) TW200706538A (en)
UY (1) UY29664A1 (en)
WO (1) WO2007009638A2 (en)
ZA (1) ZA200801523B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007015598A1 (en) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Use of fluorochemical compounds for diagnostic purposes using imaging techniques
EP2240206B1 (en) * 2008-01-08 2017-03-22 Lantheus Medical Imaging, Inc. N-alkoxyamide conjugates as imaging agents
EP4037691A4 (en) * 2019-10-04 2023-11-22 United States Government as Represented by The Department of Veterans Affairs Development of imaging and therapeutic glucose analogues for sodium dependent glucose transporters
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
CN114181164A (en) * 2021-12-13 2022-03-15 武汉大学中南医院 Synthesis method and application of MRI contrast agent based on Fe (II) specificity
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317588C2 (en) * 1993-05-24 1998-04-16 Schering Ag Macrocyclic metal complexes containing fluorine, process for their preparation and their use
DE19603033A1 (en) * 1996-01-19 1997-07-24 Schering Ag Perfluoroalkyl-containing metal complexes, processes for their preparation and their use in NMR diagnostics
DE19744004C1 (en) * 1997-09-26 1999-07-22 Schering Ag Lipophilic metal complexes for necrosis and infarct imaging
DE19744003B4 (en) * 1997-09-26 2004-07-08 Schering Ag Contrast agent for infarct and necrosis imaging
DE19914101C1 (en) * 1999-03-22 2000-10-12 Schering Ag Perfluoroalkylamides, their preparation and their use in diagnostics
DE10040858C2 (en) * 2000-08-11 2003-12-18 Schering Ag Perfluoroalkyl-containing complexes with polar residues, process for their preparation and their use

Also Published As

Publication number Publication date
TW200706538A (en) 2007-02-16
ECSP088100A (en) 2008-05-30
TNSN08016A1 (en) 2009-07-14
PE20070376A1 (en) 2007-04-20
GT200600313A (en) 2007-04-23
CR9645A (en) 2008-05-21
AR054865A1 (en) 2007-07-25
BRPI0613407A2 (en) 2011-01-11
WO2007009638A2 (en) 2007-01-25
JP2009501174A (en) 2009-01-15
NO20080813L (en) 2008-04-09
CA2615443A1 (en) 2007-01-25
CN101223148A (en) 2008-07-16
WO2007009638A3 (en) 2007-04-26
UY29664A1 (en) 2007-02-28
ZA200801523B (en) 2008-11-26
KR20080043762A (en) 2008-05-19
RU2008105356A (en) 2009-08-20
EP1904463A2 (en) 2008-04-02
DE102005033902B3 (en) 2007-04-05
AU2006272025A1 (en) 2007-01-25
IL187926A0 (en) 2008-03-20

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