DOP2005000273A - NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS - Google Patents

NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS

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Publication number
DOP2005000273A
DOP2005000273A DO2005000273A DO2005000273A DOP2005000273A DO P2005000273 A DOP2005000273 A DO P2005000273A DO 2005000273 A DO2005000273 A DO 2005000273A DO 2005000273 A DO2005000273 A DO 2005000273A DO P2005000273 A DOP2005000273 A DO P2005000273A
Authority
DO
Dominican Republic
Prior art keywords
compounds
relates
derivatives
pirrolidile
novedous
Prior art date
Application number
DO2005000273A
Other languages
Spanish (es)
Inventor
Thomas Allen Chappie
John Michael Humphrey
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Priority to DO2005000273A priority Critical patent/DOP2005000273A/en
Publication of DOP2005000273A publication Critical patent/DOP2005000273A/en

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Abstract

La invención se refiere a nuevos derivados pirrolidilo de compuestos heteroaromáticos aza benzo - condensados que siren como inhibidores eficaces de la fosfodiesterasa (PDE). La invención también se refiere a compuestos que son inhibidores selectivos de la PDE - 10. La invención se refiere adicionalmente a intermedios para la preparación de tales compuestos; composiciones farmacéuticas que comprenden tales compuestos; y el use de tales compuestos en procedimientos para tratar ciertos trastornos del sistema nervioso central (SNC) u otros. La invención se refiere también a procedimientos para tratar trastornos neurodegenerativos y psiquiátricos, por ejemplo psicosis y trastornos que comprenden cognición deficiente como un síntoma.The invention relates to novel pyrrolidyl derivatives of azo benzo-condensed heteroaromatic compounds that are effective phosphodiesterase (PDE) inhibitors. The invention also relates to compounds that are selective inhibitors of PDE-10. The invention further relates to intermediates for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and the use of such compounds in procedures to treat certain disorders of the central nervous system (CNS) or others. The invention also relates to methods for treating neurodegenerative and psychiatric disorders, for example psychosis and disorders comprising poor cognition as a symptom.

DO2005000273A 2005-12-21 2005-12-21 NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS DOP2005000273A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2005000273A DOP2005000273A (en) 2005-12-21 2005-12-21 NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2005000273A DOP2005000273A (en) 2005-12-21 2005-12-21 NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS

Publications (1)

Publication Number Publication Date
DOP2005000273A true DOP2005000273A (en) 2006-06-30

Family

ID=44340241

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2005000273A DOP2005000273A (en) 2005-12-21 2005-12-21 NOVEDOUS PIRROLIDILE DERIVATIVES OF HETEROAROMATIC COMPOUNDS

Country Status (1)

Country Link
DO (1) DOP2005000273A (en)

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