CL2010001557A1 -
Compounds derived from substituted biphenyl, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising one of the compounds; and use of the composition in the preparation of medicaments to treat neurological, neurodegenerative and psychiatric disorders.
- Google Patents
Compounds derived from substituted biphenyl, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising one of the compounds; and use of the composition in the preparation of medicaments to treat neurological, neurodegenerative and psychiatric disorders.
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Application filed by Envivo Pharmaceuticals IncfiledCriticalEnvivo Pharmaceuticals Inc
Publication of CL2010001557A1publicationCriticalpatent/CL2010001557A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Compuestos derivados de bifenil sustituidos o fenil-piperidin sustituidos, inhibidores de la fosfodiesterasa 10; composición farmacéutica que los comprende; y su uso para tratar un desorden del sistema nervioso central y otros desórdenes que pueden afectar la función del mismo, tales como desórdenes neurológicos, neurodegenerativos y siquiátricos.Compounds derived from substituted biphenyl or substituted phenyl-piperidine, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising them; and its use to treat a disorder of the central nervous system and other disorders that may affect its function, such as neurological, neurodegenerative and psychiatric disorders.
CL2010001557A2008-06-252010-12-24
Compounds derived from substituted biphenyl, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising one of the compounds; and use of the composition in the preparation of medicaments to treat neurological, neurodegenerative and psychiatric disorders.
CL2010001557A1
(en)
Compounds derived from substituted biphenyl, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising one of the compounds; and use of the composition in the preparation of medicaments to treat neurological, neurodegenerative and psychiatric disorders.
Compounds derived from 1,3-disubstituted-4-phenyl-1h-pyridin-2-one, allosteric modulators of the glutamatergic receptor mglur2; Pharmaceutical composition and use of the compounds in the treatment of neurological and psychiatric conditions mediated by mglur2.
COMPOUNDS DERIVED FROM [1,6] -NAFTIRIDINONE, MODULATORS OF KINASE ACTIVITY; PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM; AND ITS USE TO TREAT PROLIFERATIVE, INFLAMMATORY, AUTO-IMMUNE DISORDERS, OF THE CENTRAL NERVOUS SYSTEM, AMONG OTHERS.
Condensed heterobicyclic compounds, phosphodiesterase type 10a inhibitors; pharmaceutical composition that includes them; and method to treat a disorder selected from neurological disorders and psychiatric disorders.
Compound derived from substituted pyrazolopyridine, lrrk2 kinase inhibitor; process of preparing said compound; pharmaceutical composition; pharmaceutical combination; use of the compound to prevent or treat a disorder selected from cancer and neurodegenerative diseases.
Compounds derived from pyrrolotriazinone as inhibitors of pi3k; pharmaceutical composition that includes them; pharmaceutical combination; use to treat respiratory, autoimmune, neurological, cardiovascular, metabolic disorders, among others.
COMPOUNDS DERIVED FROM PHENOTIAZINE; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO TREAT DIABETES, REDUCE THE LEVELS OF GLUCEMIA, ADDICTION TO NICOTINE, ADDICTION TO ALCOHOL, DISORDERS OF THE CENTRAL NERVOUS SYSTEM, BETWEEN
COMPOUNDS DERIVED FROM AZACICLILBENZAMIDAS, ANTAGONISTAS DE HISTAMINA-3; PREPARATION PROCEDURE; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUND; AND USE OF THE COMPOUND TO TREAT A NEURODEGENERATIVE DISORDER, AS ALZHEIMER, PARKINSO
DERIVATIVES OF 1-HYDROXI-2-OXO-HYDROQUINOLINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THE SAME TO TREAT COGNITIVE DEFICITS ASSOCIATED WITH SCHIZOPHRENIA AND OTHER PSYCHIATRIC AND / OR NEUROLOGICAL DISORDERS
Compounds derived from substituted biphenyl, phosphodiesterase 10 inhibitors; pharmaceutical composition comprising one of the compounds; and use of the composition in the preparation of medicaments to treat neurological, neurodegenerative and psychiatric disorders.
Heterocyclic compounds derived from substituted amide; pharmaceutical composition that includes them; and use of the compounds to treat mood disorders, cognitive disorders and schizophrenia.