DK93081A - Fremgangsmaade til fremstilling af en inhibitor for angiotensinkoverterende enzym (ace). - Google Patents
Fremgangsmaade til fremstilling af en inhibitor for angiotensinkoverterende enzym (ace).Info
- Publication number
- DK93081A DK93081A DK93081A DK93081A DK93081A DK 93081 A DK93081 A DK 93081A DK 93081 A DK93081 A DK 93081A DK 93081 A DK93081 A DK 93081A DK 93081 A DK93081 A DK 93081A
- Authority
- DK
- Denmark
- Prior art keywords
- angiotens
- enzym
- ace
- inquiry
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/121,188 US4692459A (en) | 1979-08-14 | 1980-03-03 | Anti-hypertensive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK93081A true DK93081A (da) | 1981-09-04 |
Family
ID=22395126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93081A DK93081A (da) | 1980-03-03 | 1981-03-02 | Fremgangsmaade til fremstilling af en inhibitor for angiotensinkoverterende enzym (ace). |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4692459A (fi) |
| EP (1) | EP0035383B1 (fi) |
| JP (1) | JPS56164115A (fi) |
| AT (1) | AT385038B (fi) |
| AU (1) | AU534945B2 (fi) |
| DD (1) | DD158238A5 (fi) |
| DE (1) | DE3163812D1 (fi) |
| DK (1) | DK93081A (fi) |
| FI (1) | FI76558C (fi) |
| IE (1) | IE51259B1 (fi) |
| IL (1) | IL62203A (fi) |
| NZ (1) | NZ194002A (fi) |
| PL (1) | PL229971A1 (fi) |
| PT (1) | PT70158A1 (fi) |
| ZA (1) | ZA803486B (fi) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
| JPS57209270A (en) * | 1981-06-19 | 1982-12-22 | Chugai Pharmaceut Co Ltd | Proline derivative |
| FI850948L (fi) * | 1984-03-12 | 1985-09-13 | Pfizer | Renin inhibitorer som innehaoller statin eller dess derivat. |
| US5025001A (en) * | 1988-06-15 | 1991-06-18 | Brigham And Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
| US5187183A (en) * | 1988-06-15 | 1993-02-16 | Brigham & Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
| US5356890A (en) * | 1988-06-15 | 1994-10-18 | Brigham And Women's Hospital | S-nitroso derivatives of ace inhibitors and the use thereof |
| DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| DE10115938A1 (de) * | 2001-03-30 | 2002-10-10 | Medigene Ag Ges Fuer Molekular | Verfahren zur Herstellung von Oxirancarbonsäuren und Derivaten davon |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| ES2797649T3 (es) | 2011-07-12 | 2020-12-03 | Icu Medical Inc | Dispositivo para entrega de agente antimicrobiano en un catéter transdérmico |
| WO2015168677A1 (en) | 2014-05-02 | 2015-11-05 | Excelsior Medical Corporation | Strip package for antiseptic cap |
| AU2016262400B2 (en) | 2015-05-08 | 2021-01-21 | Icu Medical, Inc. | Medical connectors configured to receive emitters of therapeutic agents |
| ES2929769T3 (es) | 2016-10-14 | 2022-12-01 | Icu Medical Inc | Tapas desinfectantes para conectores médicos |
| WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
| JP6600386B1 (ja) * | 2018-07-06 | 2019-10-30 | Ｋｙｂ株式会社 | 弁装置 |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| EP3883638A1 (en) | 2018-11-21 | 2021-09-29 | ICU Medical, Inc. | Antimicrobial device comprising a cap with ring and insert |
| CA3204371A1 (en) | 2020-12-07 | 2022-06-16 | Icu Medical, Inc. | Peritoneal dialysis caps, systems and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947575A (en) * | 1969-06-30 | 1976-03-30 | E. R. Squibb & Sons, Inc. | Peptides as argiotensin converting enzyme inhibitors |
| US3832337A (en) * | 1970-07-28 | 1974-08-27 | Squibb & Sons Inc | Peptide enzyme inhibitors |
| US3891616A (en) * | 1974-04-17 | 1975-06-24 | Squibb & Sons Inc | Hypotensive {62 -homoaminoacid nonapeptides |
| US4052511A (en) * | 1976-02-13 | 1977-10-04 | E. R. Squibb & Sons, Inc. | Carboxyacylproline derivatives |
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
| GR73585B (fi) * | 1978-09-11 | 1984-03-26 | Univ Miami |
-
1979
- 1979-09-10 PT PT70158A patent/PT70158A1/pt unknown
-
1980
- 1980-03-03 US US06/121,188 patent/US4692459A/en not_active Expired - Lifetime
- 1980-06-11 NZ NZ194002A patent/NZ194002A/xx unknown
- 1980-06-11 AU AU59227/80A patent/AU534945B2/en not_active Ceased
- 1980-06-11 ZA ZA00803486A patent/ZA803486B/xx unknown
-
1981
- 1981-02-24 IL IL62203A patent/IL62203A/xx unknown
- 1981-02-27 DE DE8181300825T patent/DE3163812D1/de not_active Expired
- 1981-02-27 EP EP81300825A patent/EP0035383B1/en not_active Expired
- 1981-03-02 DK DK93081A patent/DK93081A/da not_active Application Discontinuation
- 1981-03-02 AT AT0097081A patent/AT385038B/de not_active IP Right Cessation
- 1981-03-03 FI FI810663A patent/FI76558C/fi not_active IP Right Cessation
- 1981-03-03 IE IE460/81A patent/IE51259B1/en unknown
- 1981-03-03 DD DD81228014A patent/DD158238A5/de not_active IP Right Cessation
- 1981-03-03 PL PL22997181A patent/PL229971A1/xx unknown
- 1981-03-03 JP JP3042981A patent/JPS56164115A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0035383B1 (en) | 1984-05-30 |
| US4692459A (en) | 1987-09-15 |
| AU534945B2 (en) | 1984-02-23 |
| JPH03386B2 (fi) | 1991-01-07 |
| NZ194002A (en) | 1982-12-21 |
| IL62203A (en) | 1984-07-31 |
| AT385038B (de) | 1988-02-10 |
| AU5922780A (en) | 1981-09-10 |
| FI76558C (fi) | 1988-11-10 |
| IE810460L (en) | 1981-09-03 |
| ZA803486B (en) | 1981-06-24 |
| FI810663L (fi) | 1981-09-04 |
| FI76558B (fi) | 1988-07-29 |
| ATA97081A (de) | 1987-07-15 |
| PL229971A1 (fi) | 1982-02-01 |
| PT70158A1 (en) | 1982-03-01 |
| EP0035383A1 (en) | 1981-09-09 |
| IE51259B1 (en) | 1986-11-26 |
| DE3163812D1 (en) | 1984-07-05 |
| JPS56164115A (en) | 1981-12-17 |
| DD158238A5 (de) | 1983-01-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK93081A (da) | Fremgangsmaade til fremstilling af en inhibitor for angiotensinkoverterende enzym (ace). | |
| DK247081A (da) | Fremgansmaade til fremstilling af derivater af forbindelse ml-236b. | |
| DK376381A (da) | Fremgangsmaade til mikroindkapsling | |
| DK480381A (da) | Fremgangsmaade til fremstilling af carbostyrilforbindelser | |
| DK321481A (da) | Fremgangsmaade til fejl-korrigering af data | |
| DK349481A (da) | Enzyminhibitorer | |
| DK73080A (da) | Fremgangsmaade til fremstilling af monacolin k. | |
| DK73180A (da) | Fremgangsmaade til fremstilling af monacolin k. | |
| DK217682A (da) | Fremgangsmaade til fremstilling af koenroeg | |
| DK433781A (da) | Fremgangsmaade til fremstilling af n-(2-pyrimidinyl) piperazinylalkylazespiroalkadioner | |
| DK407583A (da) | Fremgangsmaade ved og anlaeg til bestemmelse af lerholdige formationers karakteristika | |
| DK181281A (da) | Fremgangsmaade til fremstilling af medbringernoter paa vaerktoejer | |
| DK376179A (da) | Fremgangsmaade til fremstilling af en inhibitor for angiotensinkonverterende enzym (ace). | |
| DK249681A (da) | Fremgangsmaade til fremstilling af cephemforbindelser | |
| DK274981A (da) | R femgangsmaade til stabilisering af lyophiliserede betalactame | |
| IT8122510A0 (it) | Procedimento di fosfatazione. | |
| DK151273C (da) | Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a. | |
| DK550984A (da) | Fremgangsmaade til fremstilling af protease-inhibitorer | |
| DK107181A (da) | Fremgangsmaade til fremstilling af 1-(4-arylcyclohexyl)-piperidinderivater | |
| DK152004C (da) | Gennemloebsgrill, navnlig til boeffer | |
| NO812297L (no) | Understoettelse for broenn. | |
| FI73925B (fi) | Styrsystem foer fordon. | |
| DK226881A (da) | Fremgangsmaade til fremstilling af 3-picolin | |
| DK96881A (da) | Fremgangsmaade til fremstilling af et angiotensinomdannende enzym | |
| DK153326C (da) | Fremgangsmaade til fremstilling af azoforbindelser |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |