DK84583A - Plasmid til fremstilling af human insulin - Google Patents

Plasmid til fremstilling af human insulin

Info

Publication number
DK84583A
DK84583A DK84583A DK84583A DK84583A DK 84583 A DK84583 A DK 84583A DK 84583 A DK84583 A DK 84583A DK 84583 A DK84583 A DK 84583A DK 84583 A DK84583 A DK 84583A
Authority
DK
Denmark
Prior art keywords
plasmid
human insulin
manufacturing human
manufacturing
insulin
Prior art date
Application number
DK84583A
Other languages
English (en)
Other versions
DK84583D0 (da
Inventor
Chander Prakash Bahl
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK84583D0 publication Critical patent/DK84583D0/da
Publication of DK84583A publication Critical patent/DK84583A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK84583A 1981-06-29 1983-02-24 Plasmid til fremstilling af human insulin DK84583A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27833181A 1981-06-29 1981-06-29
PCT/US1982/000858 WO1983000164A1 (en) 1981-06-29 1982-06-25 Plasmid for producing human insulin

Publications (2)

Publication Number Publication Date
DK84583D0 DK84583D0 (da) 1983-02-24
DK84583A true DK84583A (da) 1983-02-24

Family

ID=23064574

Family Applications (1)

Application Number Title Priority Date Filing Date
DK84583A DK84583A (da) 1981-06-29 1983-02-24 Plasmid til fremstilling af human insulin

Country Status (12)

Country Link
US (1) USH245H (da)
EP (1) EP0070632A3 (da)
JP (1) JPS58501227A (da)
AU (1) AU556980B2 (da)
CA (1) CA1201074A (da)
DK (1) DK84583A (da)
ES (1) ES513522A0 (da)
IL (1) IL66102A0 (da)
NO (1) NO830682L (da)
PT (1) PT75075B (da)
WO (1) WO1983000164A1 (da)
ZA (1) ZA824218B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0090433A1 (en) * 1982-03-31 1983-10-05 Genetics Institute, Inc. Creation of DNA sequences encoding modified proinsulin precursors
DE3245665A1 (de) * 1982-05-04 1983-11-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung
US5670371A (en) * 1983-07-15 1997-09-23 Bio-Technology General Corp. Bacterial expression of superoxide dismutase
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US4767709A (en) 1984-06-28 1988-08-30 The Johns Hopkins University Growth-related hormones
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
US5496924A (en) * 1985-11-27 1996-03-05 Hoechst Aktiengesellschaft Fusion protein comprising an interleukin-2 fragment ballast portion
EP0561140B1 (en) * 1986-05-20 2002-01-30 The General Hospital Corporation Methods for pharmacokinetical studies of insulin expression involving non-human transgenic mammal
US6348327B1 (en) * 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents
US20180057920A1 (en) * 2016-08-31 2018-03-01 General Electric Company Grain refinement in in706 using laves phase precipitation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5210872B2 (da) * 1973-07-14 1977-03-26
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
FI792481A (fi) * 1978-08-11 1980-02-12 Univ California Syntes av enkaroytiskt protein genom anvaendning av mikro-organismer
GR70279B (da) * 1979-09-12 1982-09-03 Univ California
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
DK582381A (da) * 1981-01-02 1982-07-03 Univ New York Remkombinat plasmid til anvendelse ved bakteriel kloning

Also Published As

Publication number Publication date
ZA824218B (en) 1983-04-27
DK84583D0 (da) 1983-02-24
CA1201074A (en) 1986-02-25
AU556980B2 (en) 1986-11-27
NO830682L (no) 1983-02-28
PT75075B (en) 1983-12-28
EP0070632A2 (en) 1983-01-26
IL66102A0 (en) 1982-09-30
EP0070632A3 (en) 1983-06-29
WO1983000164A1 (en) 1983-01-20
AU8762382A (en) 1983-02-02
ES8304430A1 (es) 1983-03-01
ES513522A0 (es) 1983-03-01
USH245H (en) 1987-04-07
PT75075A (en) 1982-07-01
JPS58501227A (ja) 1983-07-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment