DK73278A - PROCEDURE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) -ALFAPHENYL-2-PYRIDINMETHANOL OR ACID ADDITIONAL SALTS thereof - Google Patents

PROCEDURE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) -ALFAPHENYL-2-PYRIDINMETHANOL OR ACID ADDITIONAL SALTS thereof

Info

Publication number
DK73278A
DK73278A DK73278A DK73278A DK73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A
Authority
DK
Denmark
Prior art keywords
alfaphenyl
pyridinmethanol
alfa
piperidinyl
cis
Prior art date
Application number
DK73278A
Other languages
Danish (da)
Other versions
DK143229B (en
DK143229C (en
Inventor
R W Fleming
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of DK73278A publication Critical patent/DK73278A/en
Publication of DK143229B publication Critical patent/DK143229B/en
Application granted granted Critical
Publication of DK143229C publication Critical patent/DK143229C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK73278A 1977-02-25 1978-02-17 METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS. DK143229C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77220377 1977-02-25
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols

Publications (3)

Publication Number Publication Date
DK73278A true DK73278A (en) 1978-08-26
DK143229B DK143229B (en) 1981-07-27
DK143229C DK143229C (en) 1981-11-30

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK73278A DK143229C (en) 1977-02-25 1978-02-17 METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS.

Country Status (11)

Country Link
JP (1) JPS53105479A (en)
AT (1) AT358040B (en)
BE (1) BE864033A (en)
CA (1) CA1096382A (en)
CH (1) CH635095A5 (en)
DE (1) DE2806654A1 (en)
DK (1) DK143229C (en)
ES (1) ES467100A1 (en)
FR (1) FR2381761A1 (en)
GB (1) GB1581096A (en)
PH (1) PH13125A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (en) * 1991-04-05 1998-10-30 シャープ株式会社 Multipurpose steam generator

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (en) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K NEW TERTIARY BUTANOLS WITH BASIC CONSTITUENTS

Also Published As

Publication number Publication date
DK143229B (en) 1981-07-27
FR2381761B1 (en) 1982-03-26
PH13125A (en) 1979-12-12
FR2381761A1 (en) 1978-09-22
CA1096382A (en) 1981-02-24
GB1581096A (en) 1980-12-10
DK143229C (en) 1981-11-30
AT358040B (en) 1980-08-11
ES467100A1 (en) 1978-11-01
BE864033A (en) 1978-06-16
DE2806654C2 (en) 1987-07-16
CH635095A5 (en) 1983-03-15
JPS53105479A (en) 1978-09-13
ATA117078A (en) 1980-01-15
DE2806654A1 (en) 1978-08-31
JPS6257632B2 (en) 1987-12-02

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