DK72090A - Fremgangsmaade til fremstilling af et enzym, isaer tpa, ud fra celler, isaer cncm i-222-celler, samt saaledes fremstillet enzym - Google Patents

Fremgangsmaade til fremstilling af et enzym, isaer tpa, ud fra celler, isaer cncm i-222-celler, samt saaledes fremstillet enzym Download PDF

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Publication number
DK72090A
DK72090A DK072090A DK72090A DK72090A DK 72090 A DK72090 A DK 72090A DK 072090 A DK072090 A DK 072090A DK 72090 A DK72090 A DK 72090A DK 72090 A DK72090 A DK 72090A
Authority
DK
Denmark
Prior art keywords
isaer
enzym
cells
cncm
tpa
Prior art date
Application number
DK072090A
Other languages
English (en)
Other versions
DK72090D0 (da
Inventor
Michael John Kearns
Ian David Mcentee
John Robert North
Original Assignee
Porton Prod Ltd
Health Lab Service Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Porton Prod Ltd, Health Lab Service Board filed Critical Porton Prod Ltd
Publication of DK72090D0 publication Critical patent/DK72090D0/da
Publication of DK72090A publication Critical patent/DK72090A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK072090A 1987-10-01 1990-03-20 Fremgangsmaade til fremstilling af et enzym, isaer tpa, ud fra celler, isaer cncm i-222-celler, samt saaledes fremstillet enzym DK72090A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878723082A GB8723082D0 (en) 1987-10-01 1987-10-01 Enzyme production
PCT/GB1988/000758 WO1989002917A1 (en) 1987-10-01 1988-09-16 Production of plasminogen activator from cells at which lectin is added to the culture medium

Publications (2)

Publication Number Publication Date
DK72090D0 DK72090D0 (da) 1990-03-20
DK72090A true DK72090A (da) 1990-03-20

Family

ID=10624657

Family Applications (1)

Application Number Title Priority Date Filing Date
DK072090A DK72090A (da) 1987-10-01 1990-03-20 Fremgangsmaade til fremstilling af et enzym, isaer tpa, ud fra celler, isaer cncm i-222-celler, samt saaledes fremstillet enzym

Country Status (11)

Country Link
US (1) US5002877A (da)
EP (1) EP0395652A1 (da)
JP (1) JPH03500362A (da)
AU (1) AU613100B2 (da)
BR (1) BR8807724A (da)
DK (1) DK72090A (da)
FI (1) FI901664A7 (da)
GB (1) GB8723082D0 (da)
HU (1) HU205382B (da)
WO (1) WO1989002917A1 (da)
ZA (1) ZA887110B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9000629D0 (en) * 1990-01-11 1990-03-14 Porton Prod Ltd Tissue plasminogen activator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
FR2548211B1 (fr) * 1983-06-29 1985-10-18 Choay Sa Procede de production d'un activateur tissulaire du plasminogene et activateur obtenu par ce procede
US4757005A (en) * 1984-04-19 1988-07-12 Miles Inc. Method and cell line for obtaining plasminogen activators
US4889808A (en) * 1985-10-01 1989-12-26 American Home Products Method of enchancing t-PA and SCU-PA production
JPS63152977A (ja) * 1986-12-16 1988-06-25 Snow Brand Milk Prod Co Ltd 新規な型のプラスミノ−ゲン活性化因子の製造方法

Also Published As

Publication number Publication date
BR8807724A (pt) 1990-07-24
HU885490D0 (en) 1990-11-28
US5002877A (en) 1991-03-26
EP0395652A1 (en) 1990-11-07
JPH03500362A (ja) 1991-01-31
WO1989002917A1 (en) 1989-04-06
GB8723082D0 (en) 1987-11-04
AU2428888A (en) 1989-04-18
DK72090D0 (da) 1990-03-20
FI901664A0 (fi) 1990-04-02
HUT53935A (en) 1990-12-28
HU205382B (en) 1992-04-28
AU613100B2 (en) 1991-07-25
FI901664A7 (fi) 1990-04-02
ZA887110B (en) 1989-05-30

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment