DK578485A - Dihydropyridin-carboxylsyreamider, deres fremstilling og anvendelse i laegemidler - Google Patents
Dihydropyridin-carboxylsyreamider, deres fremstilling og anvendelse i laegemidler Download PDFInfo
- Publication number
- DK578485A DK578485A DK578485A DK578485A DK578485A DK 578485 A DK578485 A DK 578485A DK 578485 A DK578485 A DK 578485A DK 578485 A DK578485 A DK 578485A DK 578485 A DK578485 A DK 578485A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- carboxylic acid
- acid amides
- medicinal products
- dihydropyridine carboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843445852 DE3445852A1 (de) | 1984-12-15 | 1984-12-15 | Dihydropyridin-carbonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK578485D0 DK578485D0 (da) | 1985-12-13 |
| DK578485A true DK578485A (da) | 1986-06-16 |
Family
ID=6252899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK578485A DK578485A (da) | 1984-12-15 | 1985-12-13 | Dihydropyridin-carboxylsyreamider, deres fremstilling og anvendelse i laegemidler |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4707479A (fr) |
| EP (1) | EP0185964B1 (fr) |
| JP (1) | JPH0631224B2 (fr) |
| AT (1) | ATE50571T1 (fr) |
| AU (1) | AU5107085A (fr) |
| CA (1) | CA1259996A (fr) |
| DE (2) | DE3445852A1 (fr) |
| DK (1) | DK578485A (fr) |
| ES (4) | ES8700850A1 (fr) |
| HU (1) | HUT40081A (fr) |
| ZA (1) | ZA859550B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN164232B (fr) * | 1986-04-11 | 1989-02-04 | Hoechst India | |
| DE3712369A1 (de) * | 1987-04-11 | 1988-10-27 | Bayer Ag | Substituierte 5-nitro-1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung |
| DE3712371A1 (de) * | 1987-04-11 | 1988-10-27 | Bayer Ag | Substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung |
| DE3724909A1 (de) * | 1987-07-28 | 1989-02-09 | Bayer Ag | Neue substituierte nitro-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung |
| GB8804439D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Dihydropyridines |
| DE3833892A1 (de) * | 1988-10-05 | 1990-04-12 | Bayer Ag | Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| WO1990009377A1 (fr) * | 1989-02-17 | 1990-08-23 | Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr | Sels alcalins d'acide sulfonique 2-(2,6-dimethyle-3,5-diethoxycarbonyle-1,4-dihydropyridine-4-carboxamido) ethane et leur procede d'obtention |
| CA2069877A1 (fr) * | 1990-10-02 | 1992-04-03 | Michio Nakanishi | Derive ethynylphenylique a substitution par de la pyridazinone et medicament contre les troubles circulatoires qui en contient comme ingredient actif |
| US5100892A (en) * | 1990-11-13 | 1992-03-31 | Glaxo Inc. | Dihydropyridine vasodilator agents |
| DE4118707A1 (de) * | 1991-06-07 | 1992-12-10 | Bayer Ag | Pharmazeutische verwendung von 3-formyl-1,4-dihydropyridinen, neue verbindungen und verfahren zu ihrer herstellung |
| DE4202526A1 (de) * | 1992-01-30 | 1993-08-05 | Bayer Ag | Neue 4-cinnolinyl- und 4-naphthyridinyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE50103978D1 (de) * | 2000-02-04 | 2004-11-11 | Lonza Ag | Verfahren zur herstellung von acetoacetylierten aromatischen aminen |
| BR0315103A (pt) | 2002-10-07 | 2005-08-16 | Artesian Therapeutics Inc | Compostos de diidropiridina tendo capacidade simultânea de bloquear os canais de cálcio do tipo l e inibir a atividade da fosfodiesterase do tipo 3 |
| WO2018086703A1 (fr) | 2016-11-11 | 2018-05-17 | Bayer Pharma Aktiengesellschaft | Dihydropyridazinones substituées par des phénylurées |
| US20200360531A1 (en) | 2018-01-31 | 2020-11-19 | Bayer Aktiengesellschaft | Antibody drug conjugates (adcs) with nampt inhibitors |
| WO2021013693A1 (fr) | 2019-07-23 | 2021-01-28 | Bayer Pharma Aktiengesellschaft | Conjugués anticorps-médicament (adc) avec des inhibiteurs de nampt |
| JPWO2022114187A1 (fr) * | 2020-11-30 | 2022-06-02 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2752820A1 (de) * | 1977-11-26 | 1979-05-31 | Bayer Ag | Neue nitrosubstituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE3279123D1 (de) * | 1981-10-20 | 1988-11-24 | Mitsui Toatsu Chemicals | Novel pyridazinone derivatives |
| DE3319956A1 (de) * | 1983-06-01 | 1984-12-06 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
-
1984
- 1984-12-15 DE DE19843445852 patent/DE3445852A1/de not_active Withdrawn
-
1985
- 1985-11-30 AT AT85115209T patent/ATE50571T1/de not_active IP Right Cessation
- 1985-11-30 DE DE8585115209T patent/DE3576156D1/de not_active Expired - Lifetime
- 1985-11-30 EP EP85115209A patent/EP0185964B1/fr not_active Expired - Lifetime
- 1985-12-05 US US06/806,057 patent/US4707479A/en not_active Expired - Fee Related
- 1985-12-10 AU AU51070/85A patent/AU5107085A/en not_active Abandoned
- 1985-12-12 ES ES549873A patent/ES8700850A1/es not_active Expired
- 1985-12-13 HU HU854781A patent/HUT40081A/hu unknown
- 1985-12-13 JP JP60279387A patent/JPH0631224B2/ja not_active Expired - Lifetime
- 1985-12-13 DK DK578485A patent/DK578485A/da not_active Application Discontinuation
- 1985-12-13 CA CA000497582A patent/CA1259996A/fr not_active Expired
- 1985-12-13 ZA ZA859550A patent/ZA859550B/xx unknown
-
1986
- 1986-08-01 ES ES556986A patent/ES8801207A1/es not_active Expired
- 1986-08-01 ES ES556988A patent/ES8801208A1/es not_active Expired
- 1986-08-01 ES ES556987A patent/ES8707501A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK578485D0 (da) | 1985-12-13 |
| DE3445852A1 (de) | 1986-06-19 |
| ES556988A0 (es) | 1987-12-16 |
| ES8700850A1 (es) | 1986-11-16 |
| EP0185964B1 (fr) | 1990-02-28 |
| ZA859550B (en) | 1986-08-27 |
| EP0185964A3 (en) | 1986-12-03 |
| AU5107085A (en) | 1986-06-19 |
| DE3576156D1 (de) | 1990-04-05 |
| ES556986A0 (es) | 1987-12-16 |
| ES549873A0 (es) | 1986-11-16 |
| CA1259996A (fr) | 1989-09-26 |
| US4707479A (en) | 1987-11-17 |
| JPH0631224B2 (ja) | 1994-04-27 |
| ES556987A0 (es) | 1987-08-01 |
| ES8707501A1 (es) | 1987-08-01 |
| EP0185964A2 (fr) | 1986-07-02 |
| ES8801208A1 (es) | 1987-12-16 |
| HUT40081A (en) | 1986-11-28 |
| ATE50571T1 (de) | 1990-03-15 |
| JPS61145180A (ja) | 1986-07-02 |
| ES8801207A1 (es) | 1987-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |