DK547378A - 1-n-4,6-di-o(aminoglycosyl-)-1,3-dimino-cyclitol-derivater deres fremstilling og anvendelse - Google Patents

1-n-4,6-di-o(aminoglycosyl-)-1,3-dimino-cyclitol-derivater deres fremstilling og anvendelse

Info

Publication number
DK547378A
DK547378A DK547378A DK547378A DK547378A DK 547378 A DK547378 A DK 547378A DK 547378 A DK547378 A DK 547378A DK 547378 A DK547378 A DK 547378A DK 547378 A DK547378 A DK 547378A
Authority
DK
Denmark
Prior art keywords
aminoglycosyl
dimino
preparation
cyclitol
derivatives
Prior art date
Application number
DK547378A
Other languages
Danish (da)
English (en)
Inventor
U Petersen
E Voss
K G Metzger
P Stadler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK547378A publication Critical patent/DK547378A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK547378A 1977-12-02 1978-12-01 1-n-4,6-di-o(aminoglycosyl-)-1,3-dimino-cyclitol-derivater deres fremstilling og anvendelse DK547378A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772753769 DE2753769A1 (de) 1977-12-02 1977-12-02 1-n-4,6-di-o-(aminoglykosyl)-1,3- diamino-cyclitol-derivate, verfahren zu ihrer herstellung sowie ihre verwendung

Publications (1)

Publication Number Publication Date
DK547378A true DK547378A (da) 1979-06-03

Family

ID=6025197

Family Applications (1)

Application Number Title Priority Date Filing Date
DK547378A DK547378A (da) 1977-12-02 1978-12-01 1-n-4,6-di-o(aminoglycosyl-)-1,3-dimino-cyclitol-derivater deres fremstilling og anvendelse

Country Status (10)

Country Link
US (1) US4234572A (it)
EP (1) EP0002450B1 (it)
JP (1) JPS5484554A (it)
AT (1) AT363595B (it)
AU (1) AU524007B2 (it)
CA (1) CA1108608A (it)
DE (2) DE2753769A1 (it)
DK (1) DK547378A (it)
ES (1) ES475633A1 (it)
IT (1) IT7830404A0 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2936120A1 (de) * 1978-09-14 1980-03-27 Sandoz Ag Neue aminoglykoside, deren herstellung und deren verwendung als antimikrobielle mittel
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
JPS5629598A (en) * 1979-08-18 1981-03-24 Toyo Jozo Co Ltd Novel amino sugar antibiotic g-367-2 and its preparation
DE2921974A1 (de) * 1979-05-30 1980-12-11 Bayer Ag Selektiv geschuetzte 1-n-(omega-aminoalkyloxycarbonyl)-sisomicin-derivate
DE3000841A1 (de) * 1980-01-11 1981-07-16 Bayer Ag, 5090 Leverkusen Isolierung und reinigung von aminoglycosid-antibiotiaka
DE3101376A1 (de) 1981-01-17 1982-09-02 Bayer Ag, 5090 Leverkusen Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4493831A (en) * 1982-10-25 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives
FR2683223B1 (fr) * 1991-11-05 1995-04-28 Stepan Europe Composes amphiphiles, a double tete sucre agent tensioactif et agent vesiculaire comprenant un tel compose et procede de preparation dudit compose.
ES2613936T3 (es) 2007-11-21 2017-05-29 Achaogen, Inc. Análogos de aminoglucósido antibacterianos
CN106188175B (zh) * 2009-05-14 2020-08-11 轩竹(北京)医药科技有限公司 使用抗菌氨基糖苷化合物治疗肺炎克雷伯杆菌感染
AR076584A1 (es) * 2009-05-14 2011-06-22 Achaogen Inc Metodo para tratar infeccion bacteriana. regimenes de dosificacion de aminoglicosidos. un aminoglucosido
WO2010132777A2 (en) * 2009-05-14 2010-11-18 Achaogen, Inc. Treatment of urinary tract infections with antibacterial aminoglycoside compounds
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207582A1 (es) * 1974-03-19 1976-10-15 Scherico Ltd Procedimiento para preparar derivados de diaminociclitole
JPS5126876A (en) * 1974-08-08 1976-03-05 Suami T Shinkina nitorosonyosojudotaino seizohoho
US4062947A (en) * 1975-11-04 1977-12-13 Schering Corporation Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor
US4053591A (en) * 1976-06-30 1977-10-11 Schering Corporation 5-deoxy-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, method for their use as antibacterial agents and compositions useful therefor

Also Published As

Publication number Publication date
JPS5484554A (en) 1979-07-05
AU4211978A (en) 1979-06-07
DE2753769A1 (de) 1979-06-13
ATA856178A (de) 1981-01-15
IT7830404A0 (it) 1978-11-30
ES475633A1 (es) 1979-04-16
AU524007B2 (en) 1982-08-26
AT363595B (de) 1981-08-10
EP0002450A1 (de) 1979-06-27
CA1108608A (en) 1981-09-08
DE2860728D1 (en) 1981-08-27
US4234572A (en) 1980-11-18
EP0002450B1 (de) 1981-05-20

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Legal Events

Date Code Title Description
ATS Application withdrawn